Motif ID: NR3C1.p2

Z-value: 1.681


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR3C1hg19_v1_chr5_-_142783288_1427834460.212.4e-01Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_92680784 12.091 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_92681025 9.802 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr3_-_111314181 9.638 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr5_-_172755418 5.636 STC2
stanniocalcin 2
chr7_-_122339186 5.401 NM_139175
RNF133
ring finger protein 133
chr8_+_103563847 5.146 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr3_-_19975671 5.140 NM_144715
EFHB
EF-hand domain family, member B
chr17_+_45286713 4.945 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr11_+_111126706 4.945 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr6_+_134210264 4.927 TCF21
transcription factor 21
chr7_-_16844606 4.892 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chr7_+_105603656 4.717 NM_152750
CDHR3
cadherin-related family member 3
chr6_+_134210247 4.682 NM_198392
NM_003206
TCF21

transcription factor 21

chr5_+_94727047 4.610 NM_152548
FAM81B
family with sequence similarity 81, member B
chr2_-_56412904 4.442 LOC100129434
uncharacterized LOC100129434
chr1_-_183622447 4.371 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr4_-_139163222 4.179 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr7_-_88425030 4.169 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr19_-_36643770 4.113 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr12_-_91572328 4.087 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr7_+_117864711 4.041 NM_019644
ANKRD7
ankyrin repeat domain 7
chr18_-_24442534 3.957 NM_004028
AQP4
aquaporin 4
chr1_-_153085963 3.929 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr11_-_65638672 3.777 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr5_+_137203559 3.772 MYOT
myotilin
chr2_-_85895863 3.692 NM_000542
NM_198843
SFTPB

surfactant protein B

chr16_+_30386097 3.665 NM_013292
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr1_-_178840079 3.562 NM_004673
ANGPTL1
angiopoietin-like 1
chr7_+_23286384 3.521 GPNMB
glycoprotein (transmembrane) nmb
chr3_-_149375584 3.496 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr20_+_20033157 3.474 NM_015585
C20orf26
chromosome 20 open reading frame 26
chr7_+_23286390 3.425 GPNMB
glycoprotein (transmembrane) nmb
chr10_+_24755459 3.360 KIAA1217
KIAA1217
chr6_+_150690027 3.314 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr7_+_23286386 3.293 GPNMB
glycoprotein (transmembrane) nmb
chr19_-_35625989 3.233 NM_139284
LGI4
leucine-rich repeat LGI family, member 4
chrY_+_16168097 3.156 NM_181880
NM_004679
VCY1B
VCX3A
VCY
variable charge, Y-linked 1B
variable charge, X-linked 3A
variable charge, Y-linked
chr17_+_61562177 3.065 NM_001178057
NM_152830
ACE

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

chr19_-_45826232 3.030 NM_001824
CKM
creatine kinase, muscle
chr20_+_30598244 2.942 NM_080625
C20orf160
chromosome 20 open reading frame 160
chr1_-_147232684 2.913 NM_181703
GJA5
gap junction protein, alpha 5, 40kDa
chrX_-_70326637 2.825 NM_001025265
CXorf65
chromosome X open reading frame 65
chr10_+_24755440 2.724 KIAA1217
KIAA1217
chr5_+_180467224 2.654 NM_152547
BTNL9
butyrophilin-like 9
chr14_-_21058388 2.640 NM_145250
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr20_+_138121 2.634 NM_139074
DEFB127
defensin, beta 127
chr14_-_21029089 2.629 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr7_-_122342965 2.619 NM_198085
RNF148
ring finger protein 148
chr17_+_37824506 2.606 NM_002686
PNMT
phenylethanolamine N-methyltransferase
chr13_+_76194569 2.597 NM_005358
LMO7
LIM domain 7
chr11_-_118047145 2.591 SCN2B
sodium channel, voltage-gated, type II, beta
chr12_-_71551564 2.507 TSPAN8
tetraspanin 8
chr11_-_36619776 2.449 NM_000536
NM_001243785
NM_001243786
RAG2


recombination activating gene 2


chrX_+_18709044 2.440 NM_006240
NM_152224
NM_152226
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr2_+_159651828 2.436 NM_001017920
DAPL1
death associated protein-like 1
chr5_+_180467265 2.428 BTNL9
butyrophilin-like 9
chr19_-_35625610 2.373 LGI4
leucine-rich repeat LGI family, member 4
chr17_-_46115135 2.359 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr6_-_47009992 2.307 NM_025048
NM_153840
GPR110

G protein-coupled receptor 110

chr16_-_5115939 2.287 C16orf89
chromosome 16 open reading frame 89
chr6_-_89927495 2.251 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr2_+_231860838 2.246 NM_139073
SPATA3
spermatogenesis associated 3
chr11_-_119187811 2.220 NM_006500
MCAM
melanoma cell adhesion molecule
chr7_+_23286401 2.200 GPNMB
glycoprotein (transmembrane) nmb
chr14_+_63671101 2.170 NM_020663
RHOJ
ras homolog gene family, member J
chr3_+_132316080 2.145 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr5_+_55062712 2.102 NM_001166534
DDX4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr3_+_11267666 2.075 NM_001098211
HRH1
histamine receptor H1
chr17_+_11786218 2.066 NM_004662
DNAH9
dynein, axonemal, heavy chain 9
chr17_+_7328934 2.050 NM_175734
C17orf74
chromosome 17 open reading frame 74
chr17_+_21308447 2.039 NM_001194958
KCNJ18
potassium inwardly-rectifying channel, subfamily J, member 18
chr11_-_102826433 2.036 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr11_-_8739398 2.030 ST5
suppression of tumorigenicity 5
chr3_+_51860898 1.999 NM_001085479
NM_001207023
IQCF3

IQ motif containing F3

chr19_+_15121538 1.972 NM_173482
CCDC105
coiled-coil domain containing 105
chr7_+_20655244 1.965 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr7_-_156468369 1.955


chr16_-_67517715 1.936 NM_001138
AGRP
agouti related protein homolog (mouse)
chr11_-_33722285 1.921 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr1_-_153521717 1.903 NM_002960
S100A3
S100 calcium binding protein A3
chr7_+_94539209 1.838 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr18_+_32398225 1.807 NM_001198942
NM_001198944
NM_032980
NM_032981
DTNA



dystrobrevin, alpha



chr17_+_45286427 1.795 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr1_+_162602308 1.790 DDR2
discoidin domain receptor tyrosine kinase 2
chrX_-_100548044 1.781 NM_024885
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr14_-_21058880 1.776 NM_001024822
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr21_-_31588242 1.751 NM_199328
CLDN8
claudin 8
chr1_-_182922504 1.736 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr5_-_149324282 1.719 NM_000440
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr7_-_84751246 1.691 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr5_-_16738346 1.683 MYO10
myosin X
chrX_+_115301957 1.678 NM_000686
AGTR2
angiotensin II receptor, type 2
chr14_-_80697396 1.666 NM_000793
DIO2
deiodinase, iodothyronine, type II
chr9_+_90532876 1.663 NM_001145124
FAM75C1
family with sequence similarity 75, member C1
chr12_+_3068442 1.655 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chrY_-_20935503 1.609 NM_001001877
NM_153716
NM_152584
NM_033108
HSFY2

HSFY1

heat shock transcription factor, Y linked 2

heat shock transcription factor, Y-linked 1

chr5_+_140560979 1.601 NM_020957
PCDHB16
protocadherin beta 16
chr22_-_17073440 1.596 NM_014406
CCT8L2
chaperonin containing TCP1, subunit 8 (theta)-like 2
chrY_+_20708556 1.594 NM_153716
NM_001001877
NM_033108
NM_152584
HSFY2

HSFY1

heat shock transcription factor, Y linked 2

heat shock transcription factor, Y-linked 1

chr14_+_20295607 1.589 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr14_-_92333856 1.579 NM_001128596
TC2N
tandem C2 domains, nuclear
chr3_-_146213721 1.576 NM_001199979
PLSCR2
phospholipid scramblase 2
chr6_-_48078909 1.573 C6orf138
chromosome 6 open reading frame 138
chr3_-_116164363 1.542 NM_002338
LSAMP
limbic system-associated membrane protein
chr1_-_10856704 1.538 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr17_-_80797889 1.534 NM_024702
ZNF750
zinc finger protein 750
chr8_-_30891230 1.514 NM_001015508
PURG
purine-rich element binding protein G
chr7_+_23286277 1.498 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr6_-_49844808 1.487 NM_001205220
CRISP1
cysteine-rich secretory protein 1
chr11_-_121986800 1.475 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr15_-_70994608 1.465 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_-_117747017 1.448 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr7_-_97501680 1.445 ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr6_-_52628272 1.433 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr12_+_81101407 1.405 NM_002469
MYF6
myogenic factor 6 (herculin)
chr7_+_123565908 1.400 NM_001174045
NM_001174046
SPAM1

sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)

chrX_-_45060081 1.393 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr6_+_36644236 1.390 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr7_+_116395440 1.389


chr3_-_151176496 1.387 NM_178822
IGSF10
immunoglobulin superfamily, member 10
chr10_+_112404104 1.379 NM_001134363
RBM20
RNA binding motif protein 20
chr7_+_123565285 1.372 NM_001174044
NM_003117
NM_153189
SPAM1


sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)


chr7_-_7575449 1.351 NM_001037763
COL28A1
collagen, type XXVIII, alpha 1
chr5_+_137203544 1.337 NM_001135940
NM_006790
MYOT

myotilin

chr5_-_95018659 1.333 NM_031952
SPATA9
spermatogenesis associated 9
chr1_+_162602198 1.333 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chrX_+_48114796 1.322 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr9_-_90749899 1.318 NM_001166137
FAM75C2
family with sequence similarity 75, member C2
chr10_-_101690655 1.314 DNMBP
dynamin binding protein
chr19_-_9609243 1.301 NM_152476
ZNF560
zinc finger protein 560
chr5_+_140710203 1.296 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr5_+_147648374 1.290 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr5_-_169816637 1.289 NM_004137
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr21_+_41239346 1.281 NM_006198
PCP4
Purkinje cell protein 4
chr1_-_54483802 1.279 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr1_+_183114214 1.275 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr7_+_128355425 1.266 NM_032599
FAM71F1
family with sequence similarity 71, member F1
chr16_+_67381252 1.263 NM_001161575
LRRC36
leucine rich repeat containing 36
chr13_+_113777112 1.262 NM_000504
F10
coagulation factor X
chr14_-_65346554 1.258 SPTB
spectrin, beta, erythrocytic
chr19_+_58570606 1.249 NM_001164527
NM_001164529
NM_001164530
NM_003436
NM_007134
ZNF135




zinc finger protein 135




chrX_+_65382627 1.249 HEPH
hephaestin
chr3_+_130279177 1.231 NM_001102608
COL6A6
collagen, type VI, alpha 6
chr4_+_120056938 1.217 NM_016599
MYOZ2
myozenin 2
chr7_-_48068644 1.216 NM_001030019
NM_152782
SUN3

Sad1 and UNC84 domain containing 3

chrX_-_43741500 1.212 MAOB
monoamine oxidase B
chr1_+_43766565 1.211 NM_001253357
NM_005424
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chrX_+_48687282 1.211 NM_181532
ERAS
ES cell expressed Ras
chr4_+_37962055 1.202 NM_006607
PTTG2
pituitary tumor-transforming 2
chr6_-_50016363 1.190 NM_001037498
DEFB112
defensin, beta 112
chr6_-_123957941 1.184 NM_001251987
NM_006073
TRDN

triadin

chr3_+_148583042 1.177 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr9_-_95298251 1.164 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr11_+_101785924 1.164 KIAA1377
KIAA1377
chr12_+_5153084 1.163 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr15_-_42448769 1.161 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr18_-_53068942 1.146


chr7_-_104567089 1.142 LOC723809
uncharacterized LOC723809
chr1_+_33004771 1.135 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr15_+_67000929 1.127 NM_001142861
SMAD6
SMAD family member 6
chr14_-_74025643 1.116 NM_001220484
NM_203309
HEATR4

HEAT repeat containing 4

chr10_-_47173917 1.114 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr4_-_77328457 1.105 NM_001042784
CCDC158
coiled-coil domain containing 158
chr22_-_37403838 1.090 NM_001163857
NM_178552
C22orf33

chromosome 22 open reading frame 33

chr8_+_24298442 1.083 NM_003817
ADAM7
ADAM metallopeptidase domain 7
chr5_+_140529619 1.080 NM_018939
PCDHB6
protocadherin beta 6
chr1_+_35225341 1.075 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr15_+_90234027 1.065 NM_020212
WDR93
WD repeat domain 93
chr11_-_26743545 1.057 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr2_+_48807725 1.054 NM_001198594
STON1
STON1-GTF2A1L
stonin 1
STON1-GTF2A1L readthrough
chr1_+_179560747 1.051 NM_001199091
NM_001199085
NM_173533
TDRD5


tudor domain containing 5


chr18_-_53068755 1.047 TCF4
transcription factor 4
chr13_+_46276445 1.043 NM_152719
SPERT
spermatid associated
chr10_-_76868853 1.041 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr1_+_159173802 1.031 NM_002036
DARC
Duffy blood group, chemokine receptor
chr11_-_102651321 1.030 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chrX_+_114423962 1.026 NM_001145346
RBMXL3
RNA binding motif protein, X-linked-like 3
chr16_+_90089007 1.009 NM_001481
GAS8
growth arrest-specific 8
chr7_+_123249076 1.003 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr6_-_49834188 1.002 NM_001131
NM_170609
CRISP1

cysteine-rich secretory protein 1

chr7_+_55980330 0.992 NM_182633
ZNF713
zinc finger protein 713
chr2_-_237172987 0.992 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr15_+_59908724 0.991 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr8_-_13372183 0.983 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr9_-_71590754 0.977


chrX_-_52736210 0.974 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chr1_+_84874033 0.973 NM_058248
DNASE2B
deoxyribonuclease II beta
chr1_-_242162364 0.972 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr1_-_117753476 0.957 NM_001253850
NM_024626
VTCN1

V-set domain containing T cell activation inhibitor 1

chr12_-_117742856 0.953 NM_001204213
NOS1
nitric oxide synthase 1 (neuronal)
chr10_-_69455926 0.935 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr11_-_3803310 0.935 NUP98
nucleoporin 98kDa
chr7_+_127233688 0.934 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr17_+_42925278 0.931 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr16_-_5115919 0.922 C16orf89
chromosome 16 open reading frame 89
chr20_-_42815732 0.915 JPH2
junctophilin 2
chr8_-_12973752 0.899 NM_001164271
DLC1
deleted in liver cancer 1
chr4_+_113970784 0.896 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr20_+_43343523 0.888 WISP2
WNT1 inducible signaling pathway protein 2
chr19_-_51334747 0.888 NM_017509
NM_138563
NM_138564
KLK15


kallikrein-related peptidase 15



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.16 3.73e-03 GO:0005509 calcium ion binding