Motif ID: NR4A2.p2

Z-value: 2.693


Transcription factors associated with NR4A2.p2:

monomer

Gene SymbolEntrez IDGene Name
NR4A2 4929 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR4A2hg19_v1_chr2_-_157186681_157186700-0.183.2e-01Click!


Activity profile for motif NR4A2.p2.

activity profile for motif NR4A2.p2


Sorted Z-values histogram for motif NR4A2.p2

Sorted Z-values for motif NR4A2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR4A2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_236849753 20.476 NM_001103
ACTN2
actinin, alpha 2
chr20_-_62130390 13.017 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr5_+_80529138 10.506 NM_001099735
NM_001099736
NM_001825
CKMT2


creatine kinase, mitochondrial 2 (sarcomeric)


chrX_-_21776158 9.245 NM_014332
SMPX
small muscle protein, X-linked
chr3_-_42744318 9.195 NM_020707
HHATL
hedgehog acyltransferase-like
chr16_-_4292052 8.263 NM_001098814
SRL
sarcalumenin
chr2_+_88367298 8.255 NM_198274
SMYD1
SET and MYND domain containing 1
chr22_-_36019363 8.137 NM_203377
MB
myoglobin
chr8_+_67039130 7.889 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr17_+_4854383 7.423 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr3_-_194072004 7.194 NM_001080513
CPN2
carboxypeptidase N, polypeptide 2
chr11_-_64528186 6.993 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr6_-_53530505 6.727 NM_001003760
KLHL31
kelch-like 31 (Drosophila)
chr1_-_229569839 6.238 NM_001100
ACTA1
actin, alpha 1, skeletal muscle
chr1_-_154164551 6.086 NM_152263
TPM3
tropomyosin 3
chr4_+_41614725 6.000 LIMCH1
LIM and calponin homology domains 1
chr4_-_65275000 5.876 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr3_-_47957475 5.831


chr5_+_145316120 5.793 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr2_+_170366211 5.787 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr16_+_6069094 5.699 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr4_+_41614933 5.654 LIMCH1
LIM and calponin homology domains 1
chr1_+_228395740 5.533 NM_001098623
NM_052843
OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

chr7_-_44180911 5.440 NM_021223
MYL7
myosin, light chain 7, regulatory
chr3_+_159557649 5.246 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr12_+_56075418 5.204 METTL7B
methyltransferase like 7B
chr6_-_123957941 5.151 NM_001251987
NM_006073
TRDN

triadin

chr4_+_41614911 5.074 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr3_-_196242190 4.989 NM_001077657
C3orf43
chromosome 3 open reading frame 43
chr12_+_56075329 4.954 NM_152637
METTL7B
methyltransferase like 7B
chr19_-_4517715 4.789 NM_001080400
PLIN4
perilipin 4
chr2_+_168043792 4.775 NM_001199144
NM_001199145
XIRP2

xin actin-binding repeat containing 2

chr3_+_186435097 4.771 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr6_+_17282931 4.681 NM_153020
RBM24
RNA binding motif protein 24
chr2_+_220299699 4.642 NM_005876
SPEG
SPEG complex locus
chr11_-_119234628 4.575 USP2
ubiquitin specific peptidase 2
chr1_-_201346804 4.511 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr17_+_7533452 4.493 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr1_-_144994908 4.476 PDE4DIP
phosphodiesterase 4D interacting protein
chr11_-_45307617 4.472 NM_001247987
NM_020826
SYT13

synaptotagmin XIII

chr2_-_207024103 4.444 NM_001199981
NM_001199982
NM_001199983
NM_005006
NDUFS1



NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)



chr20_-_42816217 4.150 NM_020433
NM_175913
JPH2

junctophilin 2

chr22_+_31518923 4.143 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr12_+_119616594 4.082 NM_014365
HSPB8
heat shock 22kDa protein 8
chr10_-_76859247 4.066 NM_016364
DUSP13
dual specificity phosphatase 13
chr3_-_50340979 4.046 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr4_+_100495972 3.988 MTTP
microsomal triglyceride transfer protein
chr17_-_27948345 3.921 NM_032854
CORO6
coronin 6
chr8_+_1993157 3.911 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr1_+_160085519 3.901 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr5_-_142077508 3.834 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr1_+_167064086 3.763 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr3_+_159557745 3.762 SCHIP1
schwannomin interacting protein 1
chr12_-_56106061 3.747 NM_001144997
ITGA7
integrin, alpha 7
chr19_-_55668956 3.707 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr3_-_187009469 3.555 NM_001031849
NM_001879
NM_139125
MASP1


mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)


chr10_+_88428167 3.530 NM_001171610
LDB3
LIM domain binding 3
chr2_+_103236147 3.530 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr14_+_24600674 3.472 NM_203402
FITM1
fat storage-inducing transmembrane protein 1
chr2_-_211168315 3.408 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr16_-_2004670 3.371 NM_005061
RPL3L
ribosomal protein L3-like
chr5_+_149569519 3.342 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr15_-_40630272 3.305 C15orf52
chromosome 15 open reading frame 52
chr1_-_144994839 3.297 PDE4DIP
phosphodiesterase 4D interacting protein
chr2_+_27505296 3.295 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr9_+_139839697 3.293 NM_000606
C8G
complement component 8, gamma polypeptide
chr1_+_16062808 3.192 NM_207348
SLC25A34
solute carrier family 25, member 34
chr2_-_21225640 3.186 APOB
apolipoprotein B (including Ag(x) antigen)
chr12_-_70093064 3.170 NM_032735
BEST3
bestrophin 3
chr1_-_24434927 3.149 MYOM3
myomesin family, member 3
chr5_+_145317297 3.062 SH3RF2
SH3 domain containing ring finger 2
chr4_+_159593233 3.012 NM_004453
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr15_-_83621350 3.004 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr14_-_94442894 2.989 ASB2
ankyrin repeat and SOCS box containing 2
chr9_+_12693385 2.958 NM_000550
TYRP1
tyrosinase-related protein 1
chr10_-_50970321 2.936 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr9_-_112191105 2.923 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr10_-_115423640 2.899 NM_006175
NM_198060
NRAP

nebulin-related anchoring protein

chr16_+_58534045 2.874 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr18_-_43678230 2.857 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr17_+_7184978 2.849 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr1_+_145413190 2.846 NM_145277
NM_202004
NM_213652
NM_213653
HFE2



hemochromatosis type 2 (juvenile)



chr15_+_63050761 2.846 TLN2
talin 2
chr9_+_17578952 2.831 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr15_+_43885251 2.792 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr18_-_43678251 2.791 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr18_-_43678195 2.759 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr3_-_52488030 2.736 NM_003280
TNNC1
troponin C type 1 (slow)
chr12_+_109577201 2.717 NM_001093
ACACB
acetyl-CoA carboxylase beta
chr15_-_75230354 2.713 COX5A
cytochrome c oxidase subunit Va
chr9_-_138853146 2.712 NM_016172
UBAC1
UBA domain containing 1
chr19_-_4535202 2.680 NM_001013706
PLIN5
perilipin 5
chr6_-_33714681 2.674 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr1_-_116311330 2.672 CASQ2
calsequestrin 2 (cardiac muscle)
chr11_-_47470687 2.672 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr1_-_17380486 2.668 NM_003000
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr1_-_116311161 2.638 CASQ2
calsequestrin 2 (cardiac muscle)
chr4_-_111563278 2.629 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr11_-_73720281 2.610 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr18_-_43678233 2.606 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr12_-_96184346 2.601 NTN4
netrin 4
chr7_-_10979683 2.598 NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr2_-_152590983 2.593 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr9_-_97356007 2.587 NM_003837
FBP2
fructose-1,6-bisphosphatase 2
chr9_+_139846767 2.571 NM_178536
LCN12
lipocalin 12
chr4_+_72204769 2.543 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr1_+_64088886 2.539 NM_001172818
PGM1
phosphoglucomutase 1
chr16_+_30386097 2.525 NM_013292
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_+_103378489 2.485 NM_144632
TMEM182
transmembrane protein 182
chr16_+_72097124 2.475 NM_020995
HPR
haptoglobin-related protein
chr10_-_74714479 2.465 NM_032562
PLA2G12B
phospholipase A2, group XIIB
chr15_+_78441737 2.450 IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr13_+_29598746 2.418 NM_001033602
MTUS2
microtubule associated tumor suppressor candidate 2
chr14_+_21498344 2.416 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr8_+_145149985 2.403 CYC1
cytochrome c-1
chr4_-_177190258 2.399 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr5_+_53751430 2.390 NM_006308
HSPB3
heat shock 27kDa protein 3
chr19_+_35629727 2.381 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr1_-_151804225 2.369 NM_005060
RORC
RAR-related orphan receptor C
chr8_-_107782417 2.361 NM_139166
ABRA
actin-binding Rho activating protein
chr1_-_216978708 2.359 NM_001243514
ESRRG
estrogen-related receptor gamma
chr1_+_68151092 2.350 GADD45A
growth arrest and DNA-damage-inducible, alpha
chr9_-_138853007 2.345 UBAC1
UBA domain containing 1
chr11_+_34938112 2.338 PDHX
pyruvate dehydrogenase complex, component X
chr11_+_111896076 2.332 DLAT
dihydrolipoamide S-acetyltransferase
chr16_-_31439650 2.332 NM_005205
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr1_-_217113007 2.327 NM_001243512
NM_001243513
NM_001243510
NM_001243511
ESRRG



estrogen-related receptor gamma



chr11_+_116700620 2.325 NM_000040
APOC3
apolipoprotein C-III
chr11_-_66139064 2.323 NM_001532
SLC29A2
solute carrier family 29 (nucleoside transporters), member 2
chr18_-_3219846 2.318 MYOM1
myomesin 1, 185kDa
chr6_-_24489738 2.318 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr18_-_43678257 2.309 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr3_+_158991035 2.306 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr20_-_33999760 2.303 UQCC
ubiquinol-cytochrome c reductase complex chaperone
chr1_-_27240430 2.292 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr18_-_44336991 2.258 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chrX_+_70521627 2.254 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr10_+_123872440 2.248 TACC2
transforming, acidic coiled-coil containing protein 2
chr11_-_107582733 2.248 NM_003063
SLN
sarcolipin
chr5_-_150727088 2.229 NM_181776
SLC36A2
solute carrier family 36 (proton/amino acid symporter), member 2
chr19_+_33166312 2.211 NM_207391
RGS9BP
regulator of G protein signaling 9 binding protein
chrX_+_152954965 2.207 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr1_+_44412640 2.187 IPO13
importin 13
chr2_+_26467615 2.170 NM_000183
HADHB
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
chr17_+_42836546 2.158 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr15_-_75230386 2.154 NM_004255
COX5A
cytochrome c oxidase subunit Va
chr7_-_10979752 2.152 NM_002489
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr12_-_57039785 2.147 NM_001686
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr7_+_37960162 2.142 NM_001242946
NM_017549
EPDR1

ependymin related protein 1 (zebrafish)

chr7_+_123249076 2.135 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr8_-_124553253 2.126 FBXO32
F-box protein 32
chr12_-_57039736 2.124 ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr1_+_44412582 2.120 IPO13
importin 13
chr9_+_74764394 2.102 GDA
guanine deaminase
chr1_+_16348365 2.097 NM_001042704
NM_004070
CLCNKA

CLCNKB
chloride channel Ka

chloride channel Kb
chr20_+_17207680 2.095 PCSK2
proprotein convertase subtilisin/kexin type 2
chr12_-_96184510 2.088 NM_021229
NTN4
netrin 4
chr15_+_78441678 2.085 NM_005530
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr6_+_146348781 2.084 NM_000838
NM_001114329
GRM1

glutamate receptor, metabotropic 1

chr18_-_43678273 2.075 NM_004046
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr15_+_78441733 2.069 IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr12_-_111358353 2.059 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr4_+_71494460 2.058 NM_031889
ENAM
enamelin
chrX_-_21676416 2.047 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr2_-_219696511 2.041 NM_017431
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr6_+_158734902 2.040


chr15_-_42783293 2.037 ZFP106
zinc finger protein 106 homolog (mouse)
chrX_-_129299680 2.026 AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr7_-_99381703 1.986 NM_001202855
NM_017460
CYP3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

chr17_+_27370155 1.986 PIPOX
pipecolic acid oxidase
chr8_+_145729464 1.983 NM_005309
GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
chr11_+_22696318 1.979 NM_005256
GAS2
growth arrest-specific 2
chrX_+_135230736 1.974 NM_001159700
FHL1
four and a half LIM domains 1
chr16_+_31225341 1.971 NM_001008274
TRIM72
tripartite motif containing 72
chr12_-_81991959 1.971 NM_001220477
NM_001220478
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr15_+_52311432 1.968 MAPK6
mitogen-activated protein kinase 6
chr11_-_118550354 1.961 NM_007180
TREH
trehalase (brush-border membrane glycoprotein)
chr22_-_24110054 1.959 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr10_-_74714563 1.957 PLA2G12B
phospholipase A2, group XIIB
chr4_-_140216951 1.942 NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr3_-_38691118 1.938 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr5_-_133340380 1.933 VDAC1
voltage-dependent anion channel 1
chr2_+_26467809 1.933 HADHB
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
chr11_+_20044362 1.933 NAV2
neuron navigator 2
chr5_-_133340389 1.931 VDAC1
voltage-dependent anion channel 1
chr1_+_54359859 1.928 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr12_-_122296619 1.923 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr9_+_95947211 1.911 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr5_-_133340358 1.901 VDAC1
voltage-dependent anion channel 1
chr2_-_21231406 1.900 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_-_8129378 1.867 ABLIM2
actin binding LIM protein family, member 2
chr1_-_46685962 1.866 NM_001243766
POMGNT1
protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase
chr20_+_57875647 1.860 EDN3
endothelin 3
chr19_+_13134782 1.856 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_19223516 1.853 NM_001127656
NM_003476
CSRP3

cysteine and glycine-rich protein 3 (cardiac LIM protein)

chr5_-_133340427 1.850 VDAC1
voltage-dependent anion channel 1
chr17_-_27949814 1.841 CORO6
coronin 6
chr3_-_48647085 1.838 NM_003365
UQCRC1
ubiquinol-cytochrome c reductase core protein I
chr13_+_76334796 1.837 NM_015842
LMO7
LIM domain 7
chr3_-_46718898 1.831 NM_182775
ALS2CL
ALS2 C-terminal like

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
9.08 2.72e-19 GO:0003012 muscle system process
9.28 2.65e-18 GO:0006936 muscle contraction
9.70 7.28e-15 GO:0045333 cellular respiration
11.31 2.18e-14 GO:0022904 respiratory electron transport chain
4.94 4.50e-13 GO:0006091 generation of precursor metabolites and energy
5.73 4.54e-12 GO:0015980 energy derivation by oxidation of organic compounds
8.13 3.53e-11 GO:0022900 electron transport chain
2.89 1.54e-08 GO:0055114 oxidation-reduction process
14.07 2.03e-07 GO:0030049 muscle filament sliding
14.07 2.03e-07 GO:0033275 actin-myosin filament sliding
13.70 2.80e-07 GO:0070252 actin-mediated cell contraction
5.40 4.29e-07 GO:0007517 muscle organ development
11.13 6.03e-07 GO:0030048 actin filament-based movement
11.83 1.59e-06 GO:0042773 ATP synthesis coupled electron transport
11.83 1.59e-06 GO:0042775 mitochondrial ATP synthesis coupled electron transport
10.62 5.51e-06 GO:0006119 oxidative phosphorylation
4.02 4.17e-05 GO:0061061 muscle structure development
11.51 6.74e-05 GO:0006941 striated muscle contraction
2.64 2.11e-04 GO:0019752 carboxylic acid metabolic process
2.64 2.11e-04 GO:0043436 oxoacid metabolic process
2.59 3.57e-04 GO:0042180 cellular ketone metabolic process
2.58 3.70e-04 GO:0006082 organic acid metabolic process
6.85 6.50e-04 GO:0090257 regulation of muscle system process
10.51 7.96e-04 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
6.96 1.84e-03 GO:0006937 regulation of muscle contraction
1.84 1.87e-03 GO:0044281 small molecule metabolic process
10.04 5.66e-03 GO:0009060 aerobic respiration
12.90 5.73e-03 GO:0006942 regulation of striated muscle contraction
12.90 5.73e-03 GO:0034367 macromolecular complex remodeling
12.90 5.73e-03 GO:0034368 protein-lipid complex remodeling
12.90 5.73e-03 GO:0034369 plasma lipoprotein particle remodeling
3.06 1.20e-02 GO:0044057 regulation of system process
1.78 1.47e-02 GO:0003008 system process
10.92 1.64e-02 GO:0071825 protein-lipid complex subunit organization
10.92 1.64e-02 GO:0071827 plasma lipoprotein particle organization
3.16 2.25e-02 GO:0030029 actin filament-based process
2.37 2.82e-02 GO:0048878 chemical homeostasis
4.18 3.84e-02 GO:0006006 glucose metabolic process
4.41 4.92e-02 GO:0014706 striated muscle tissue development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
11.16 4.41e-20 GO:0043292 contractile fiber
11.42 1.20e-19 GO:0030016 myofibril
11.31 8.93e-19 GO:0044449 contractile fiber part
11.59 7.93e-17 GO:0030017 sarcomere
5.88 7.30e-16 GO:0005743 mitochondrial inner membrane
5.53 1.97e-15 GO:0019866 organelle inner membrane
3.72 1.93e-13 GO:0044429 mitochondrial part
4.50 3.67e-13 GO:0031966 mitochondrial membrane
1.45 4.09e-13 GO:0005737 cytoplasm
1.60 1.27e-12 GO:0044444 cytoplasmic part
4.30 1.63e-12 GO:0005740 mitochondrial envelope
2.55 1.92e-10 GO:0005739 mitochondrion
3.19 1.39e-09 GO:0031967 organelle envelope
7.49 1.89e-09 GO:0044455 mitochondrial membrane part
3.13 2.54e-09 GO:0031975 envelope
10.04 1.91e-08 GO:0070469 respiratory chain
14.07 4.06e-08 GO:0016529 sarcoplasmic reticulum
13.70 5.61e-08 GO:0016528 sarcoplasm
4.14 5.28e-07 GO:0015629 actin cytoskeleton
9.31 1.09e-06 GO:0005746 mitochondrial respiratory chain
9.86 1.21e-05 GO:0031674 I band
1.83 2.80e-05 GO:0031090 organelle membrane
21.83 3.10e-05 GO:0031672 A band
1.40 1.43e-04 GO:0044422 organelle part
9.96 2.48e-04 GO:0030018 Z disc
9.71 3.06e-04 GO:0005747 mitochondrial respiratory chain complex I
9.71 3.06e-04 GO:0030964 NADH dehydrogenase complex
9.71 3.06e-04 GO:0045271 respiratory chain complex I
3.60 3.94e-04 GO:0005759 mitochondrial matrix
19.71 6.87e-04 GO:0042627 chylomicron
18.20 1.10e-03 GO:0005865 striated muscle thin filament
6.65 1.80e-03 GO:0016459 myosin complex
1.78 5.79e-03 GO:0005856 cytoskeleton
11.83 1.17e-02 GO:0034361 very-low-density lipoprotein particle
11.83 1.17e-02 GO:0034385 triglyceride-rich lipoprotein particle
11.27 1.51e-02 GO:0033017 sarcoplasmic reticulum membrane
1.15 1.97e-02 GO:0044424 intracellular part
8.11 1.97e-02 GO:0032994 protein-lipid complex
8.11 1.97e-02 GO:0034358 plasma lipoprotein particle
28.38 2.16e-02 GO:0033018 sarcoplasmic reticulum lumen
3.04 3.43e-02 GO:0005792 microsome
1.30 3.74e-02 GO:0044446 intracellular organelle part
23.65 4.25e-02 GO:0031430 M band
2.93 4.96e-02 GO:0042598 vesicular fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.07 2.43e-07 GO:0003779 actin binding
12.10 3.49e-07 GO:0008307 structural constituent of muscle
2.83 1.09e-06 GO:0016491 oxidoreductase activity
3.13 1.55e-06 GO:0008092 cytoskeletal protein binding
2.22 1.49e-04 GO:0022892 substrate-specific transporter activity
2.08 2.18e-04 GO:0005215 transporter activity
10.23 2.85e-04 GO:0003954 NADH dehydrogenase activity
10.23 2.85e-04 GO:0008137 NADH dehydrogenase (ubiquinone) activity
10.23 2.85e-04 GO:0050136 NADH dehydrogenase (quinone) activity
3.72 3.46e-04 GO:0048037 cofactor binding
4.16 5.72e-04 GO:0015077 monovalent inorganic cation transmembrane transporter activity
3.66 8.40e-04 GO:0022890 inorganic cation transmembrane transporter activity
8.80 9.59e-04 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
5.37 2.17e-03 GO:0015078 hydrogen ion transmembrane transporter activity
2.13 4.58e-03 GO:0022891 substrate-specific transmembrane transporter activity
2.21 6.17e-03 GO:0015075 ion transmembrane transporter activity
2.02 1.04e-02 GO:0022857 transmembrane transporter activity
2.30 2.68e-02 GO:0008324 cation transmembrane transporter activity
9.86 4.27e-02 GO:0004129 cytochrome-c oxidase activity
9.86 4.27e-02 GO:0015002 heme-copper terminal oxidase activity
9.86 4.27e-02 GO:0016675 oxidoreductase activity, acting on a heme group of donors
9.86 4.27e-02 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
1.31 4.73e-02 GO:0003824 catalytic activity