Motif ID: NR5A1,2.p2

Z-value: 2.120


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v1_chr1_+_199996729_1999970100.467.7e-03Click!
NR5A1hg19_v1_chr9_-_127269689_127269719-0.019.5e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_80529138 7.453 NM_001099735
NM_001099736
NM_001825
CKMT2


creatine kinase, mitochondrial 2 (sarcomeric)


chr11_-_119234628 6.129 USP2
ubiquitin specific peptidase 2
chr10_-_101190201 5.916 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr1_-_27240430 5.830 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr1_+_236849753 5.559 NM_001103
ACTN2
actinin, alpha 2
chr7_-_44105162 4.971 NM_000290
PGAM2
phosphoglycerate mutase 2 (muscle)
chr6_+_118869441 4.739 NM_002667
PLN
phospholamban
chr12_-_111358353 4.620 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr10_+_115310589 4.577 NM_001177660
HABP2
hyaluronan binding protein 2
chr4_+_41614911 4.518 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_-_70361578 4.385 NM_021139
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr7_+_116166346 4.328 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr19_-_45826131 4.306 CKM
creatine kinase, muscle
chr8_-_107782417 4.262 NM_139166
ABRA
actin-binding Rho activating protein
chr19_-_4535202 4.089 NM_001013706
PLIN5
perilipin 5
chr2_+_27505296 4.020 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr1_+_167064086 3.986 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr1_-_171621750 3.985 NM_000261
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr5_+_42565963 3.983 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr12_-_122296619 3.922 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr2_+_170366211 3.916 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr4_+_41614933 3.840 LIMCH1
LIM and calponin homology domains 1
chr5_-_41213513 3.800 NM_000065
C6
complement component 6
chr10_+_88428167 3.735 NM_001171610
LDB3
LIM domain binding 3
chr3_-_42744318 3.611 NM_020707
HHATL
hedgehog acyltransferase-like
chr2_-_179672056 3.606 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr4_+_41614725 3.560 LIMCH1
LIM and calponin homology domains 1
chr17_-_27948345 3.505 NM_032854
CORO6
coronin 6
chr20_-_62130390 3.468 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr12_+_119616594 3.411 NM_014365
HSPB8
heat shock 22kDa protein 8
chr12_+_7167979 3.401 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr22_+_41865112 3.294 NM_001098
ACO2
aconitase 2, mitochondrial
chr18_-_44336991 3.287 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr11_+_12960793 3.271 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr10_-_75415748 3.248 NM_001114133
SYNPO2L
synaptopodin 2-like
chr13_-_33859835 3.214 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr22_+_31518923 3.157 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr5_-_122372320 3.148 PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr7_+_123249076 3.138 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr5_+_145316120 3.116 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr3_+_119316694 3.084 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr3_-_47957475 3.074


chr19_-_55668956 3.057 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr1_+_32050510 3.053 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr4_+_77610610 3.046 SHROOM3
shroom family member 3
chr4_+_30721865 3.026 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr12_+_48516428 3.020 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr9_-_14314036 2.998 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr3_+_52812438 2.955 NM_001166434
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr22_-_36019363 2.934 NM_203377
MB
myoglobin
chr20_-_42815732 2.931 JPH2
junctophilin 2
chr11_+_1940798 2.927 NM_001042780
NM_001042781
NM_001042782
NM_006757
TNNT3



troponin T type 3 (skeletal, fast)



chr12_+_109577201 2.923 NM_001093
ACACB
acetyl-CoA carboxylase beta
chr20_+_30598244 2.906 NM_080625
C20orf160
chromosome 20 open reading frame 160
chr2_+_120189342 2.904 NM_183240
TMEM37
transmembrane protein 37
chrX_-_21776158 2.895 NM_014332
SMPX
small muscle protein, X-linked
chr11_+_114167197 2.881 NNMT
nicotinamide N-methyltransferase
chr1_-_144997110 2.870 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_217262946 2.864 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr17_-_73505914 2.829 NM_001142643
CASKIN2
CASK interacting protein 2
chr11_-_119234859 2.820 NM_171997
USP2
ubiquitin specific peptidase 2
chr2_-_238499713 2.812 NM_022449
RAB17
RAB17, member RAS oncogene family
chr12_-_106532447 2.804 NUAK1
NUAK family, SNF1-like kinase, 1
chr19_-_36643770 2.755 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr5_-_122372413 2.744 NM_000943
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr6_+_17282931 2.738 NM_153020
RBM24
RNA binding motif protein 24
chr10_-_97321094 2.738 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr12_+_57849086 2.737 NM_031479
INHBE
inhibin, beta E
chr21_-_27107184 2.690 ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr11_+_114167168 2.686 NNMT
nicotinamide N-methyltransferase
chr9_-_130639939 2.677 NM_000476
AK1
adenylate kinase 1
chr22_-_36013303 2.673 NM_005368
NM_203378
MB

myoglobin

chr12_-_53298765 2.661 NM_002273
KRT8
keratin 8
chr12_+_52306112 2.659 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr3_-_187009469 2.654 NM_001031849
NM_001879
NM_139125
MASP1


mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)


chr1_+_145413190 2.646 NM_145277
NM_202004
NM_213652
NM_213653
HFE2



hemochromatosis type 2 (juvenile)



chr10_-_76818271 2.627 NM_001003892
DUPD1
dual specificity phosphatase and pro isomerase domain containing 1
chr15_-_83621350 2.587 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr7_-_82072804 2.582 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr20_+_30193083 2.525 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr4_+_120056938 2.511 NM_016599
MYOZ2
myozenin 2
chr7_+_116139619 2.511 NM_001206747
NM_001233
NM_198212
CAV2


caveolin 2


chr2_-_218843541 2.475 TNS1
tensin 1
chr13_+_23755059 2.461 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr17_+_37821598 2.456 NM_003673
TCAP
titin-cap (telethonin)
chr14_-_61115906 2.452 NM_005982
SIX1
SIX homeobox 1
chr20_-_42816217 2.445 NM_020433
NM_175913
JPH2

junctophilin 2

chr6_-_135271206 2.441 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr5_+_42565562 2.432 NM_001242406
GHR
growth hormone receptor
chr8_+_136469557 2.420 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr10_+_88426538 2.417 LDB3
LIM domain binding 3
chr15_-_74043815 2.412 NM_001039614
C15orf59
chromosome 15 open reading frame 59
chr3_+_121312169 2.390 NM_016298
FBXO40
F-box protein 40
chr7_-_82073020 2.380 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr1_+_54359859 2.359 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chrX_-_43741500 2.331 MAOB
monoamine oxidase B
chr2_-_238499317 2.327 RAB17
RAB17, member RAS oncogene family
chr12_-_9268440 2.315 A2M
alpha-2-macroglobulin
chr13_-_114103452 2.305 NM_199162
ADPRHL1
ADP-ribosylhydrolase like 1
chr16_-_75285383 2.298 NM_001170717
NM_014567
BCAR1

breast cancer anti-estrogen resistance 1

chr5_+_32710742 2.294 NM_001204376
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chrX_+_152770083 2.279 BGN
biglycan
chr15_+_63050761 2.276 TLN2
talin 2
chr10_-_50970321 2.271 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr14_-_61190458 2.231 NM_017420
SIX4
SIX homeobox 4
chr15_-_35087748 2.225 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr16_+_20420854 2.216 NM_017888
ACSM5
acyl-CoA synthetase medium-chain family member 5
chr5_-_138842291 2.215 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr17_-_48265912 2.210 COL1A1
collagen, type I, alpha 1
chr2_+_241375030 2.203 NM_002081
GPC1
glypican 1
chr20_+_39969420 2.191 NM_022896
LPIN3
lipin 3
chr20_+_36974823 2.184 NM_004139
LBP
lipopolysaccharide binding protein
chr5_+_87564729 2.183 LOC100505894
uncharacterized LOC100505894
chr2_+_98262497 2.178 NM_001862
COX5B
cytochrome c oxidase subunit Vb
chr12_-_9268475 2.164 A2M
alpha-2-macroglobulin
chr17_-_10452939 2.161 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr12_-_9268513 2.160 A2M
alpha-2-macroglobulin
chr11_-_10590078 2.148 NM_006691
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr9_+_72658735 2.148 MAMDC2
MAM domain containing 2
chr1_-_217263195 2.145 NM_001243505
ESRRG
estrogen-related receptor gamma
chr11_-_58499368 2.144 NM_005838
NM_201648
GLYAT

glycine-N-acyltransferase

chr19_-_45826232 2.132 NM_001824
CKM
creatine kinase, muscle
chr2_-_161056762 2.131 ITGB6
integrin, beta 6
chr3_-_49460110 2.118 NM_000481
NM_001164710
NM_001164711
NM_001164712
AMT



aminomethyltransferase



chr16_+_57481336 2.115 NM_020312
COQ9
coenzyme Q9 homolog (S. cerevisiae)
chr3_+_52813936 2.108 NM_001166435
NM_001166436
ITIH1

inter-alpha-trypsin inhibitor heavy chain 1

chr4_-_152096655 2.087 NM_001128924
SH3D19
SH3 domain containing 19
chr10_-_115423640 2.084 NM_006175
NM_198060
NRAP

nebulin-related anchoring protein

chr5_+_176516550 2.080 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr3_+_14860468 2.080 NM_152536
FGD5
FYVE, RhoGEF and PH domain containing 5
chr5_-_134914968 2.073 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr7_+_95115212 2.069 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr12_+_56075418 2.069 METTL7B
methyltransferase like 7B
chr4_+_111397181 2.068 NM_001977
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr12_-_9268522 2.067 NM_000014
A2M
alpha-2-macroglobulin
chr9_-_14313509 2.063 NFIB
nuclear factor I/B
chr5_+_145317297 2.060 SH3RF2
SH3 domain containing ring finger 2
chr17_-_10421858 2.057 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr5_-_11903964 2.055 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr17_-_79792923 2.041 NM_001007533
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr9_-_14086901 2.040 NFIB
nuclear factor I/B
chr15_-_75230354 2.023 COX5A
cytochrome c oxidase subunit Va
chr16_-_67223998 2.020 NM_178516
EXOC3L1
exocyst complex component 3-like 1
chr12_+_56075329 2.016 NM_152637
METTL7B
methyltransferase like 7B
chr5_+_71403040 2.012 NM_005909
MAP1B
microtubule-associated protein 1B
chr1_-_144994908 2.007 PDE4DIP
phosphodiesterase 4D interacting protein
chr11_+_7506599 2.000 NM_198474
OLFML1
olfactomedin-like 1
chr11_-_47470687 1.994 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr5_+_137203559 1.993 MYOT
myotilin
chr2_+_241375235 1.987 GPC1
glypican 1
chr17_-_79792867 1.986 PPP1R27
protein phosphatase 1, regulatory subunit 27
chrX_+_152954965 1.980 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr6_+_31973358 1.975 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr2_-_161056573 1.969 NM_000888
ITGB6
integrin, beta 6
chr6_+_101846860 1.965 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr3_-_38691118 1.959 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr10_+_60937226 1.956 NM_001143774
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr19_-_4517715 1.953 NM_001080400
PLIN4
perilipin 4
chr22_+_30792929 1.952 NM_001204204
NM_012429
NM_033382
SEC14L2


SEC14-like 2 (S. cerevisiae)


chr5_-_38556682 1.948 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr1_+_162351519 1.941 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr1_+_38022514 1.940 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr17_-_48266572 1.940 COL1A1
collagen, type I, alpha 1
chr6_+_32006092 1.912 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr1_-_86043932 1.905 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr19_+_35550794 1.900 HPN
hepsin
chr18_-_56296188 1.900 NM_052947
ALPK2
alpha-kinase 2
chr16_-_75150617 1.893 LDHD
lactate dehydrogenase D
chr19_-_46916825 1.890 NM_032040
CCDC8
coiled-coil domain containing 8
chr19_+_11350282 1.877 NM_018687
C19orf80
chromosome 19 open reading frame 80
chr13_+_24883715 1.873 NM_178540
C1QTNF9
C1q and tumor necrosis factor related protein 9
chr11_-_64528186 1.873 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chrX_+_23926122 1.869 NM_001169574
NM_152761
CXorf58

chromosome X open reading frame 58

chr11_-_16424391 1.865 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr1_+_162039469 1.863 NM_001164757
NM_014697
NOS1AP

nitric oxide synthase 1 (neuronal) adaptor protein

chr12_-_114843888 1.855 NM_181486
TBX5
T-box 5
chr5_-_42811959 1.852 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr8_+_144295067 1.839 NM_178172
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr17_-_38520941 1.839 NM_152219
GJD3
gap junction protein, delta 3, 31.9kDa
chr1_+_203096835 1.837 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr1_-_144994943 1.825 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr1_-_151798552 1.806 NM_001001523
RORC
RAR-related orphan receptor C
chr5_+_218428 1.783 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr7_+_30791744 1.781 NM_001199219
NM_006774
INMT-FAM188B
INMT

INMT-FAM188B readthrough (non-protein coding)
indolethylamine N-methyltransferase

chr19_+_19626535 1.761 NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr2_+_228029280 1.752 NM_000091
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr10_-_21786186 1.750 C10orf114
chromosome 10 open reading frame 114
chr18_-_43678195 1.750 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr11_-_63933204 1.740 MACROD1
MACRO domain containing 1
chr10_+_88428263 1.738 NM_001080116
NM_001080114
NM_001080115
NM_001171611
NM_007078
LDB3




LIM domain binding 3




chr8_-_17658385 1.735 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr14_-_102975996 1.734 ANKRD9
ankyrin repeat domain 9
chr8_-_17658711 1.734


chr12_-_91505215 1.732 LUM
lumican
chr20_-_32031425 1.729 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr16_-_66959418 1.720 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr2_-_45236521 1.714 NM_016932
SIX2
SIX homeobox 2
chr17_+_7608413 1.705 NM_001406
EFNB3
ephrin-B3
chr18_-_43678230 1.702 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr19_+_11649578 1.694 NM_001299
CNN1
calponin 1, basic, smooth muscle

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
6.72 2.32e-10 GO:0003012 muscle system process
6.70 2.55e-09 GO:0006936 muscle contraction
6.02 7.86e-09 GO:0007517 muscle organ development
7.34 5.84e-08 GO:0014706 striated muscle tissue development
14.31 2.03e-07 GO:0006941 striated muscle contraction
6.72 2.67e-07 GO:0060537 muscle tissue development
4.46 1.49e-06 GO:0061061 muscle structure development
9.31 6.61e-06 GO:0007519 skeletal muscle tissue development
8.75 1.40e-05 GO:0060538 skeletal muscle organ development
3.44 6.98e-05 GO:0006091 generation of precursor metabolites and energy
11.71 7.00e-05 GO:0030049 muscle filament sliding
11.71 7.00e-05 GO:0033275 actin-myosin filament sliding
11.40 9.01e-05 GO:0070252 actin-mediated cell contraction
9.44 1.14e-04 GO:0030048 actin filament-based movement
1.82 1.53e-04 GO:0042221 response to chemical stimulus
1.84 1.79e-04 GO:0065008 regulation of biological quality
1.68 4.18e-04 GO:0048731 system development
2.02 5.11e-04 GO:0009653 anatomical structure morphogenesis
7.06 5.75e-04 GO:0002576 platelet degranulation
3.76 6.23e-04 GO:0015980 energy derivation by oxidation of organic compounds
1.43 7.83e-04 GO:0032501 multicellular organismal process
1.60 1.89e-03 GO:0048856 anatomical structure development
2.24 4.61e-03 GO:0055114 oxidation-reduction process
7.10 6.29e-03 GO:0072376 protein activation cascade
1.53 8.52e-03 GO:0007275 multicellular organismal development
2.23 8.53e-03 GO:0040011 locomotion
7.86 9.91e-03 GO:0055002 striated muscle cell development
48.11 1.27e-02 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
48.11 1.27e-02 GO:0051451 myoblast migration
2.68 1.83e-02 GO:0072358 cardiovascular system development
2.68 1.83e-02 GO:0072359 circulatory system development
1.47 1.84e-02 GO:0032502 developmental process
2.44 2.04e-02 GO:0009725 response to hormone stimulus
10.69 2.27e-02 GO:0031032 actomyosin structure organization
7.00 2.40e-02 GO:0055001 muscle cell development
4.86 2.40e-02 GO:0005976 polysaccharide metabolic process
2.05 3.21e-02 GO:0009605 response to external stimulus
8.02 3.27e-02 GO:0006956 complement activation
2.37 3.31e-02 GO:0032989 cellular component morphogenesis
1.74 4.21e-02 GO:0003008 system process
19.25 4.99e-02 GO:0006599 phosphagen metabolic process
19.25 4.99e-02 GO:0006600 creatine metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
10.79 1.82e-17 GO:0030016 myofibril
10.17 8.81e-17 GO:0043292 contractile fiber
11.29 8.51e-16 GO:0030017 sarcomere
10.22 1.89e-15 GO:0044449 contractile fiber part
2.05 4.83e-08 GO:0005576 extracellular region
2.49 5.60e-07 GO:0044421 extracellular region part
11.03 7.23e-07 GO:0031674 I band
2.72 1.01e-06 GO:0005615 extracellular space
10.18 1.79e-06 GO:0031983 vesicle lumen
3.87 8.12e-06 GO:0015629 actin cytoskeleton
10.24 8.23e-06 GO:0031093 platelet alpha granule lumen
10.03 1.02e-05 GO:0034774 secretory granule lumen
11.40 1.49e-05 GO:0030018 Z disc
9.63 1.54e-05 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
8.44 5.70e-05 GO:0031091 platelet alpha granule
18.51 1.00e-03 GO:0031672 A band
3.57 1.51e-03 GO:0016323 basolateral plasma membrane
9.63 1.52e-03 GO:0032994 protein-lipid complex
9.63 1.52e-03 GO:0034358 plasma lipoprotein particle
12.03 1.79e-03 GO:0034364 high-density lipoprotein particle
1.34 2.13e-03 GO:0044444 cytoplasmic part
4.20 3.39e-03 GO:0005912 adherens junction
2.63 6.19e-03 GO:0031966 mitochondrial membrane
2.27 6.39e-03 GO:0044429 mitochondrial part
12.66 8.15e-03 GO:0005811 lipid particle
36.09 8.27e-03 GO:0034363 intermediate-density lipoprotein particle
3.79 9.99e-03 GO:0070161 anchoring junction
12.03 1.07e-02 GO:0034361 very-low-density lipoprotein particle
12.03 1.07e-02 GO:0034385 triglyceride-rich lipoprotein particle
2.52 1.23e-02 GO:0005740 mitochondrial envelope
4.63 1.45e-02 GO:0005924 cell-substrate adherens junction
16.04 1.88e-02 GO:0034362 low-density lipoprotein particle
16.04 1.88e-02 GO:0042627 chylomicron
4.46 2.00e-02 GO:0030055 cell-substrate junction
5.35 2.86e-02 GO:0042383 sarcolemma
24.06 4.01e-02 GO:0031430 M band
2.75 4.19e-02 GO:0005743 mitochondrial inner membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.68 1.59e-05 GO:0003779 actin binding
5.28 2.28e-05 GO:0004866 endopeptidase inhibitor activity
5.07 4.02e-05 GO:0061135 endopeptidase regulator activity
5.00 4.82e-05 GO:0030414 peptidase inhibitor activity
3.72 9.48e-05 GO:0004857 enzyme inhibitor activity
4.45 1.08e-04 GO:0061134 peptidase regulator activity
8.95 8.65e-04 GO:0008307 structural constituent of muscle
2.62 1.32e-03 GO:0008092 cytoskeletal protein binding
6.02 2.10e-03 GO:0005201 extracellular matrix structural constituent
2.43 3.87e-03 GO:0005198 structural molecule activity
5.53 4.49e-03 GO:0004867 serine-type endopeptidase inhibitor activity
2.66 7.87e-03 GO:0008289 lipid binding
3.94 1.00e-02 GO:0001871 pattern binding
3.94 1.00e-02 GO:0030247 polysaccharide binding
1.97 1.51e-02 GO:0005102 receptor binding
5.92 2.02e-02 GO:0005496 steroid binding
3.93 2.05e-02 GO:0005539 glycosaminoglycan binding