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Motif ID: NR6A1.p2

Z-value: 1.753

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_48264039	15.219		COL1A1	collagen, type I, alpha 1
chr14_-_106453162	14.061		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_+_7169192	13.785
chr19_-_6720585	12.306	NM_000064	C3	complement component 3
chr22_+_23229959	11.441	NM_001178126	IGLL5 IGLC1	immunoglobulin lambda-like polypeptide 5 immunoglobulin lambda constant 1 (Mcg marker)
chr7_-_150038689	11.120	NM_002889	RARRES2	retinoic acid receptor responder (tazarotene induced) 2
chr6_+_31973358	11.014	NM_000500 NM_001128590	CYP21A2	cytochrome P450, family 21, subfamily A, polypeptide 2
chr14_-_106967528	10.507		IGHA1 IGHA2 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr9_-_14313509	9.928		NFIB	nuclear factor I/B
chr9_-_14314036	9.681	NM_001190737 NM_005596	NFIB	nuclear factor I/B
chr7_+_100199881	7.388	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr19_-_7796977	6.944	NM_001244856 NM_198492	CLEC4G	C-type lectin domain family 4, member G
chr9_-_14313899	6.306		NFIB	nuclear factor I/B
chr14_-_106539099	6.168		IGHA1 IGHG1 IGHG3	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr15_+_101420004	5.309	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr9_-_38069082	5.306		SHB	Src homology 2 domain containing adaptor protein B
chr15_+_101420032	5.144		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr14_-_106471439	4.836		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr10_-_71892514	4.809		AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2
chr9_-_14313943	4.626		NFIB	nuclear factor I/B
chr11_+_111789658	4.609		C11orf52	chromosome 11 open reading frame 52
chr1_+_176432306	4.584	NM_020318 NM_021936	PAPPA2	pappalysin 2
chr10_+_89419352	4.519	NM_001015880 NM_004670	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr3_-_126236593	4.404	NM_001165974 NM_144639	UROC1	urocanase domain containing 1
chr12_+_100897137	4.400	NM_001206992 NM_001206993	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr11_+_65192284	4.006		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr11_+_111789600	3.794	NM_080659	C11orf52	chromosome 11 open reading frame 52
chr6_+_129204285	3.719	NM_000426 NM_001079823	LAMA2	laminin, alpha 2
chr3_+_46619075	3.418	NM_003212	TDGF1	teratocarcinoma-derived growth factor 1
chr9_+_35792405	3.359	NM_003995	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr2_+_18059923	3.358	NM_002252	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr12_+_109273856	3.161	NM_001917	DAO	D-amino-acid oxidase
chr1_+_78511588	3.091	NM_017655	GIPC2	GIPC PDZ domain containing family, member 2
chrX_+_48620153	3.013	NM_001080489	GLOD5	glyoxalase domain containing 5
chr6_-_133035180	2.972	NM_004666	VNN1	vanin 1
chr3_+_186383770	2.910	NM_000412	HRG	histidine-rich glycoprotein
chr14_-_106111114	2.906		IGHG2	immunoglobulin heavy constant gamma 2 (G2m marker)
chr5_+_63802427	2.884	NM_001029875	RGS7BP	regulator of G-protein signaling 7 binding protein
chr10_-_71892596	2.727	NM_001198696 NM_032797	AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2
chr16_+_56642477	2.628	NM_005953	MT2A	metallothionein 2A
chr1_-_161168816	2.549	NM_005099	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr10_-_125651494	2.517	NM_198148	CPXM2	carboxypeptidase X (M14 family), member 2
chr5_-_41213513	2.431	NM_000065	C6	complement component 6
chr14_-_106967080	2.203		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_-_211090146	2.157	NM_001608	ACADL	acyl-CoA dehydrogenase, long chain
chr14_-_106733392	2.024		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106641585	1.848		IGHV4-31 IGHA1 IGHA2 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_63063186	1.796	NM_014495	ANGPTL3	angiopoietin-like 3
chr9_-_114362100	1.737	NM_001146108 NM_001146109	PTGR1	prostaglandin reductase 1
chr15_-_41166336	1.734	NM_133639	RHOV	ras homolog gene family, member V
chr1_+_225997742	1.676	NM_001136018	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr5_-_14011846	1.673		DNAH5	dynein, axonemal, heavy chain 5
chr18_+_33767420	1.644	NM_017947	MOCOS	molybdenum cofactor sulfurase
chr2_-_21231406	1.586		APOB	apolipoprotein B (including Ag(x) antigen)
chr1_+_225997804	1.583		EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr19_+_10196972	1.561		C19orf66	chromosome 19 open reading frame 66
chr12_-_110252600	1.560	NM_001177431 NM_001177428 NM_001177433 NM_147204	TRPV4	transient receptor potential cation channel, subfamily V, member 4
chr1_-_159825136	1.544	NM_001134233	C1orf204	chromosome 1 open reading frame 204
chr12_-_7261788	1.491	NM_016546	C1RL	complement component 1, r subcomponent-like
chr16_+_56995761	1.486	NM_000078	CETP	cholesteryl ester transfer protein, plasma
chr2_-_162930500	1.461		DPP4	dipeptidyl-peptidase 4
chr14_-_106452693	1.460		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_38069207	1.444	NM_003028	SHB	Src homology 2 domain containing adaptor protein B
chr16_-_67223998	1.441	NM_178516	EXOC3L1	exocyst complex component 3-like 1
chr9_-_130679210	1.320	NM_175039 NM_175040	ST6GALNAC4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr1_+_117452359	1.234	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr20_-_7921068	1.229	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr20_-_43024303	1.221
chr1_+_33231260	1.156		KIAA1522	KIAA1522
chr8_-_93115453	1.153	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_133465204	1.127		TF	transferrin
chr12_-_16760935	1.117	NM_001001395 NM_001243609	LMO3	LIM domain only 3 (rhombotin-like 2)
chr11_+_111957611	1.114		SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein
chr2_+_95963026	1.084	NM_013434	KCNIP3	Kv channel interacting protein 3, calsenilin
chr6_-_56407681	1.083
chr1_+_212738675	1.070	NM_001030287	ATF3	activating transcription factor 3
chr3_+_133464883	1.054	NM_001063	TF	transferrin
chr1_+_19923457	1.043	NM_001204088 NM_001204089 NM_001032363 NM_001204082 NM_001204083	C1orf151-NBL1 MINOS1	C1orf151-NBL1 readthrough mitochondrial inner membrane organizing system 1
chr9_+_124043719	1.037		GSN	gelsolin
chr5_-_42175355	0.972
chr1_+_45274153	0.881	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr4_-_48014960	0.880	NM_000087	CNGA1	cyclic nucleotide gated channel alpha 1
chr1_+_113236679	0.877		MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)
chr12_-_6484389	0.837	NM_001159576	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr7_+_73868111	0.836	NM_001199207 NM_005685 NM_016328	GTF2IRD1	GTF2I repeat domain containing 1
chr7_-_100240334	0.835		TFR2	transferrin receptor 2
chr12_+_54410893	0.806		HOXC5 HOXC6	homeobox C5 homeobox C6
chr11_-_108464344	0.788	NM_015065	EXPH5	exophilin 5
chr19_+_10197023	0.768		C19orf66	chromosome 19 open reading frame 66
chr4_+_41614725	0.765		LIMCH1	LIM and calponin homology domains 1
chr15_+_63335904	0.765		TPM1	tropomyosin 1 (alpha)
chr11_+_65383631	0.757	NM_032223	PCNXL3	pecanex-like 3 (Drosophila)
chr1_-_211666258	0.702	NM_001164688 NM_183059	RD3	retinal degeneration 3
chr22_-_24059436	0.646
chr7_+_37960162	0.637	NM_001242946 NM_017549	EPDR1	ependymin related protein 1 (zebrafish)
chr2_-_224903324	0.631	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr11_+_111957533	0.621	NM_003002	SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein
chr3_-_38178463	0.599		ACAA1	acetyl-CoA acyltransferase 1
chr22_-_24059524	0.596		GUSBP11	glucuronidase, beta pseudogene 11
chr18_+_8609407	0.595	NM_001025300	RAB12	RAB12, member RAS oncogene family
chr10_-_63212924	0.533		TMEM26	transmembrane protein 26
chr1_-_935469	0.533	NM_001142467 NM_021170	HES4	hairy and enhancer of split 4 (Drosophila)
chr7_-_65447162	0.501		GUSB	glucuronidase, beta
chr7_-_65447206	0.494		GUSB	glucuronidase, beta
chr8_+_11188494	0.493	NM_054028	SLC35G5	solute carrier family 35, member G5
chr22_-_24059502	0.483		GUSBP11	glucuronidase, beta pseudogene 11
chr8_-_145690737	0.481	NM_032687 NM_001129888	CYHR1	cysteine/histidine-rich 1
chr16_+_31494438	0.479	NM_003041	SLC5A2	solute carrier family 5 (sodium/glucose cotransporter), member 2
chr21_-_43916298	0.465	NM_080860	RSPH1	radial spoke head 1 homolog (Chlamydomonas)
chr7_+_37960418	0.464		EPDR1	ependymin related protein 1 (zebrafish)
chr2_-_162930544	0.459		DPP4	dipeptidyl-peptidase 4
chr19_-_5846465	0.433		FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr5_+_140749830	0.414	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr7_-_65447233	0.411	NM_000181	GUSB	glucuronidase, beta
chr2_-_31361591	0.410	NM_001253826 NM_024572	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_+_40997232	0.397	NM_152373	ZNF684	zinc finger protein 684
chr2_+_26568991	0.387		EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr7_+_73868236	0.387		GTF2IRD1	GTF2I repeat domain containing 1
chr3_+_133465098	0.372		TF	transferrin
chr17_-_29624249	0.362	NM_002544	OMG	oligodendrocyte myelin glycoprotein
chr7_-_87936202	0.362	NM_001205315 NM_001205316 NM_024636	STEAP4	STEAP family member 4
chr21_-_37914897	0.338	NM_001146078	CLDN14	claudin 14
chr22_+_32010152	0.329		SFI1	Sfi1 homolog, spindle assembly associated (yeast)
chr5_-_60458228	0.327	NM_001048249	C5orf43	chromosome 5 open reading frame 43
chr11_-_111957417	0.316	NM_012459	TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr2_-_162929928	0.302		DPP4	dipeptidyl-peptidase 4
chr12_+_2921786	0.281	NM_018463	ITFG2	integrin alpha FG-GAP repeat containing 2
chr6_-_30899926	0.270	NM_205854	SFTA2	surfactant associated 2
chr2_+_33172368	0.267	NM_206943	LTBP1	latent transforming growth factor beta binding protein 1
chr7_-_97601564	0.265		MGC72080	MGC72080 pseudogene
chr11_-_64764388	0.264	NM_138456	BATF2	basic leucine zipper transcription factor, ATF-like 2
chr10_+_106014467	0.258	NM_001191002 NM_004832	GSTO1	glutathione S-transferase omega 1
chr10_-_126107454	0.251		OAT	ornithine aminotransferase
chr2_+_26568900	0.236	NM_033505	EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr21_-_45682098	0.231	NM_013369 NM_175867	DNMT3L	DNA (cytosine-5-)-methyltransferase 3-like
chr1_+_9299902	0.225		H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr9_-_21228132	0.206	NM_021268	IFNA17	interferon, alpha 17
chr10_-_126107493	0.202	NM_000274 NM_001171814	OAT	ornithine aminotransferase
chr17_+_12692779	0.174	NM_014859	ARHGAP44	Rho GTPase activating protein 44
chr6_+_117803779	0.162	NM_173674	DCBLD1	discoidin, CUB and LCCL domain containing 1
chr2_-_31361364	0.138
chr7_-_2883649	0.132	NM_007353	GNA12	guanine nucleotide binding protein (G protein) alpha 12
chr10_+_106013951	0.116	NM_001191003	GSTO1	glutathione S-transferase omega 1
chr1_+_40420837	0.095		MFSD2A	major facilitator superfamily domain containing 2A
chr9_+_37485911	0.094	NM_022490	POLR1E	polymerase (RNA) I polypeptide E, 53kDa
chr19_-_16738986	0.089	NM_004831	MED26	mediator complex subunit 26
chr1_-_20834609	0.074	NM_024544	MUL1	mitochondrial E3 ubiquitin protein ligase 1
chr8_-_145701139	0.071		FOXH1	forkhead box H1
chr1_+_219347195	0.067		LYPLAL1	lysophospholipase-like 1
chr1_+_40420802	0.065		MFSD2A	major facilitator superfamily domain containing 2A
chrY_-_1460901	0.056	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr6_-_43484503	0.048		YIPF3	Yip1 domain family, member 3
chr6_-_43484701	0.038	NM_015388	YIPF3	Yip1 domain family, member 3
chr1_-_40236926	0.037	NM_022120	OXCT2	3-oxoacid CoA transferase 2
chr3_+_46411632	0.037	NM_000579 NM_001100168	CCR5	chemokine (C-C motif) receptor 5
chrX_+_48916515	0.031	NM_001163322 NM_033626 NM_001163321 NM_001163323	CCDC120	coiled-coil domain containing 120
chr19_-_43709692	0.029	NM_002780 NM_213633	PSG4	pregnancy specific beta-1-glycoprotein 4
chr16_+_776957	0.029	NM_032304	HAGHL	hydroxyacylglutathione hydrolase-like
chr1_+_219347123	0.026	NM_138794	LYPLAL1	lysophospholipase-like 1
chr1_+_76190042	0.013	NM_000016 NM_001127328	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr21_+_42688660	0.003	NM_058186 NM_206964	FAM3B	family with sequence similarity 3, member B

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
40.22	6.27e-05	GO:0002455	humoral immune response mediated by circulating immunoglobulin
4.06	4.31e-04	GO:0002376	immune system process
25.60	6.37e-04	GO:0016064	immunoglobulin mediated immune response
25.15	6.97e-04	GO:0019724	B cell mediated immunity
4.98	1.63e-03	GO:0006955	immune response
36.33	1.87e-03	GO:0006958	complement activation, classical pathway
20.41	1.98e-03	GO:0002449	lymphocyte mediated immunity
19.03	2.80e-03	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
18.53	3.20e-03	GO:0002250	adaptive immune response
17.61	4.12e-03	GO:0006959	humoral immune response
281.47	5.62e-03	GO:0001969	regulation of activation of membrane attack complex
281.47	5.62e-03	GO:0001970	positive regulation of activation of membrane attack complex
281.47	5.62e-03	GO:0045917	positive regulation of complement activation
281.47	5.62e-03	GO:2000259	positive regulation of protein activation cascade
16.19	6.21e-03	GO:0002443	leukocyte mediated immunity
26.82	6.47e-03	GO:0006956	complement activation
18.47	2.87e-02	GO:0072376	protein activation cascade
6.72	3.42e-02	GO:0032787	monocarboxylic acid metabolic process
5.54	3.96e-02	GO:0002684	positive regulation of immune system process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
3.56	7.80e-07	GO:0005576	extracellular region
4.09	4.81e-04	GO:0044421	extracellular region part
4.55	8.84e-04	GO:0005615	extracellular space
3.70	3.04e-02	GO:0005624	membrane fraction
3.58	3.92e-02	GO:0005626	insoluble fraction

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
49.27	8.57e-09	GO:0003823	antigen binding