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Motif ID: NRF1.p2

Z-value: 5.189

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_260092	8.439	NM_001013672	C17orf97	chromosome 17 open reading frame 97
chr22_-_19279183	7.720	NM_001835 NM_007098	CLTCL1	clathrin, heavy chain-like 1
chr1_+_231473681	7.031	NM_001010984 NM_032018	C1orf124	chromosome 1 open reading frame 124
chr1_+_231473773	6.323		C1orf124	chromosome 1 open reading frame 124
chr6_-_33679435	5.644		C6orf125	chromosome 6 open reading frame 125
chr6_-_33679501	5.556	NM_032340	C6orf125	chromosome 6 open reading frame 125
chr17_-_7518124	5.545	NM_004860	FXR2	fragile X mental retardation, autosomal homolog 2
chr16_+_50099907	5.496		HEATR3	HEAT repeat containing 3
chr16_+_50099880	5.221	NM_182922	HEATR3	HEAT repeat containing 3
chr12_-_54070108	5.017	NM_005176	ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr19_-_46405854	4.882	NM_001012643	MYPOP	Myb-related transcription factor, partner of profilin
chr6_+_30614815	4.865	NM_001109938 NM_001161376 NM_145029	C6orf136	chromosome 6 open reading frame 136
chr8_+_42249383	4.657		VDAC3	voltage-dependent anion channel 3
chr7_-_44365019	4.652	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr1_+_167189948	4.542	NM_001198786 NM_002697	POU2F1	POU class 2 homeobox 1
chr4_-_56412968	4.399	NM_004898	CLOCK	clock homolog (mouse)
chr1_-_231473478	4.302	NM_175876	EXOC8	exocyst complex component 8
chr6_+_111408780	4.231	NM_018593	SLC16A10	solute carrier family 16, member 10 (aromatic amino acid transporter)
chr16_+_28565279	4.192		CCDC101	coiled-coil domain containing 101
chr1_-_202858225	4.144	NM_002871	RABIF	RAB interacting factor
chr6_-_135375829	4.131		HBS1L	HBS1-like (S. cerevisiae)
chr5_-_218235	4.113	NM_145265	CCDC127	coiled-coil domain containing 127
chr1_-_3773620	4.109		CEP104	centrosomal protein 104kDa
chr5_+_218355	4.095	NM_004168	SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr12_-_54069856	4.079		ATP5G2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr19_+_18794487	4.057		CRTC1	CREB regulated transcription coactivator 1
chr16_+_28565225	4.011	NM_138414	CCDC101	coiled-coil domain containing 101
chr8_+_42249278	4.002	NM_001135694 NM_005662	VDAC3	voltage-dependent anion channel 3
chr8_+_42249393	3.924		VDAC3	voltage-dependent anion channel 3
chr19_-_50432952	3.908	NM_016553	NUP62	nucleoporin 62kDa
chr3_+_49726961	3.770		RNF123	ring finger protein 123
chr17_-_7517849	3.748		FXR2	fragile X mental retardation, autosomal homolog 2
chr17_-_27278471	3.737	NM_001033561 NM_020889	PHF12	PHD finger protein 12
chr11_-_59436366	3.726		PATL1	protein associated with topoisomerase II homolog 1 (yeast)
chr12_-_48551269	3.720	NM_024095	ASB8	ankyrin repeat and SOCS box containing 8
chr15_-_42783293	3.714		ZFP106	zinc finger protein 106 homolog (mouse)
chr19_-_55770340	3.689		PPP6R1	protein phosphatase 6, regulatory subunit 1
chr19_-_50432731	3.684		NUP62	nucleoporin 62kDa
chr5_+_79783799	3.674	NM_205548	FAM151B	family with sequence similarity 151, member B
chr1_-_110052285	3.672	NM_020703	AMIGO1	adhesion molecule with Ig-like domain 1
chr19_-_40324747	3.638	NM_004714 NM_006483 NM_006484	DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr17_-_28257017	3.593	NM_033389	SSH2	slingshot homolog 2 (Drosophila)
chr12_-_49392909	3.584	NM_015086	DDN	dendrin
chr16_+_4475804	3.583	NM_001135110 NM_005147	DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3
chr3_+_49726974	3.582	NM_022064	RNF123	ring finger protein 123
chr10_-_27389319	3.572	NM_014915	ANKRD26	ankyrin repeat domain 26
chr17_+_57970486	3.559		RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr19_-_50432734	3.522	NM_012346 NM_153718 NM_153719 NM_001193357 NM_172374	NUP62 IL4I1	nucleoporin 62kDa interleukin 4 induced 1
chrX_-_142722869	3.514	NM_173078	SLITRK4	SLIT and NTRK-like family, member 4
chr5_+_218428	3.462		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr2_+_26256728	3.457	NM_016131	RAB10	RAB10, member RAS oncogene family
chr1_+_150336584	3.426		RPRD2	regulation of nuclear pre-mRNA domain containing 2
chr3_-_53080038	3.401	NM_001005158 NM_016329	SFMBT1	Scm-like with four mbt domains 1
chr9_+_110045822	3.395		RAD23B	RAD23 homolog B (S. cerevisiae)
chr6_+_111408648	3.388		SLC16A10	solute carrier family 16, member 10 (aromatic amino acid transporter)
chr17_+_43971868	3.368		MAPT	microtubule-associated protein tau
chr9_-_139839072	3.331		FBXW5	F-box and WD repeat domain containing 5
chr9_-_124922049	3.323	NM_014222	NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr3_+_49727014	3.320		RNF123	ring finger protein 123
chr16_-_4166021	3.312		ADCY9	adenylate cyclase 9
chr10_-_98592186	3.283
chr17_-_7154994	3.279	NM_001143775	CTDNEP1	CTD nuclear envelope phosphatase 1
chr19_-_55769920	3.271	NM_014931	PPP6R1	protein phosphatase 6, regulatory subunit 1
chr16_+_89574804	3.269	NM_003119 NM_199367	SPG7	spastic paraplegia 7 (pure and complicated autosomal recessive)
chr10_-_127511832	3.252	NM_000375	UROS	uroporphyrinogen III synthase
chr17_+_43971998	3.208		MAPT	microtubule-associated protein tau
chr19_-_50432679	3.181		NUP62 IL4I1	nucleoporin 62kDa interleukin 4 induced 1
chr6_-_135375954	3.170	NM_001145158 NM_001145207 NM_006620	HBS1L	HBS1-like (S. cerevisiae)
chr4_+_7045095	3.167		TADA2B	transcriptional adaptor 2B
chr15_-_65477645	3.163		CLPX	ClpX caseinolytic peptidase X homolog (E. coli)
chr19_+_7968820	3.152		MAP2K7	mitogen-activated protein kinase kinase 7
chr11_+_66886735	3.120	NM_012308	KDM2A	lysine (K)-specific demethylase 2A
chr8_+_23104120	3.108		CHMP7	charged multivesicular body protein 7
chr9_+_110045551	3.093		RAD23B	RAD23 homolog B (S. cerevisiae)
chr1_-_160232269	3.088		DCAF8	DDB1 and CUL4 associated factor 8
chr19_+_18794391	3.082	NM_001098482 NM_015321	CRTC1	CREB regulated transcription coactivator 1
chr19_-_50432678	3.056		NUP62	nucleoporin 62kDa
chr16_+_8715473	3.049	NM_024109	METTL22	methyltransferase like 22
chr3_+_127634317	3.045		KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr17_+_3572089	3.045	NM_001014764 NM_031298	TMEM93	transmembrane protein 93
chrX_-_30907408	3.045	NM_152787	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr12_+_57916607	3.041	NM_052897	MBD6	methyl-CpG binding domain protein 6
chr1_-_243418482	3.033		CEP170	centrosomal protein 170kDa
chr11_-_59436488	2.992	NM_152716	PATL1	protein associated with topoisomerase II homolog 1 (yeast)
chr15_-_65477441	2.991	NM_006660	CLPX	ClpX caseinolytic peptidase X homolog (E. coli)
chrX_-_347689	2.985	NM_013239	PPP2R3B	protein phosphatase 2, regulatory subunit B'', beta
chr3_+_44379923	2.944	NM_001029839 NM_173826	C3orf23	chromosome 3 open reading frame 23
chr17_+_43972014	2.936		MAPT	microtubule-associated protein tau
chr1_-_16678927	2.934	NM_018994	FBXO42	F-box protein 42
chr14_+_102430767	2.923	NM_001376	DYNC1H1	dynein, cytoplasmic 1, heavy chain 1
chr5_+_218447	2.922		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr10_-_133795311	2.915	NM_004052	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3
chrX_-_7066146	2.910	NM_001135565 NM_001178135 NM_001178136 NM_012080	HDHD1	haloacid dehalogenase-like hydrolase domain containing 1
chr3_-_48647085	2.885	NM_003365	UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr5_+_218441	2.881		SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr2_+_190526124	2.871	NM_019048	ASNSD1	asparagine synthetase domain containing 1
chr17_+_3627133	2.869	NM_031965	GSG2	germ cell associated 2 (haspin)
chr7_-_6388408	2.857	NM_001037163	C7orf70	chromosome 7 open reading frame 70
chr19_-_49575878	2.846		KCNA7	potassium voltage-gated channel, shaker-related subfamily, member 7
chr9_-_139378192	2.843		SEC16A	SEC16 homolog A (S. cerevisiae)
chr16_-_4166185	2.811	NM_001116	ADCY9	adenylate cyclase 9
chr3_-_48647052	2.810		UQCRC1	ubiquinol-cytochrome c reductase core protein I
chr20_-_35580175	2.808		SAMHD1	SAM domain and HD domain 1
chr10_-_74856590	2.779		P4HA1	prolyl 4-hydroxylase, alpha polypeptide I
chr5_-_1594617	2.776		SDHAP3	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
chr7_+_100027253	2.776	NM_019606	MEPCE	methylphosphate capping enzyme
chr19_-_48867149	2.757	NM_018273	TMEM143	transmembrane protein 143
chr22_+_24666749	2.755	NM_001145468 NM_015330	SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1-like
chr9_-_139010627	2.726		C9orf69	chromosome 9 open reading frame 69
chr9_+_115142395	2.722		HSDL2	hydroxysteroid dehydrogenase like 2
chr17_+_36452988	2.721	NM_032351	MRPL45	mitochondrial ribosomal protein L45
chr2_-_37311415	2.715		HEATR5B	HEAT repeat containing 5B
chr9_-_124921981	2.715		NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr1_-_243418340	2.713		CEP170	centrosomal protein 170kDa
chr1_-_3773760	2.707	NM_014704	CEP104	centrosomal protein 104kDa
chr3_-_47517316	2.704		SCAP	SREBF chaperone
chr19_+_56111600	2.688	NM_153219	ZNF524	zinc finger protein 524
chr4_+_7045222	2.685		TADA2B	transcriptional adaptor 2B
chr3_+_133292404	2.673	NM_001134422 NM_017548	CDV3	CDV3 homolog (mouse)
chr8_-_70747200	2.668	NM_030958	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chr10_-_133795447	2.667		BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3
chr19_-_16582753	2.650	NM_021235	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1
chr1_-_84971848	2.643		GNG5	guanine nucleotide binding protein (G protein), gamma 5
chr9_+_71395079	2.639
chr19_+_42724498	2.622		ZNF526	zinc finger protein 526
chr17_+_36453124	2.619		MRPL45	mitochondrial ribosomal protein L45
chr19_+_19144370	2.615	NM_001199196 NM_033415	ARMC6	armadillo repeat containing 6
chr9_+_115142188	2.614	NM_001195822 NM_032303	HSDL2	hydroxysteroid dehydrogenase like 2
chr10_-_73611050	2.612	NM_001042465 NM_001042466 NM_002778	PSAP	prosaposin
chr16_+_3019341	2.611	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr9_+_140513451	2.606		EHMT1	euchromatic histone-lysine N-methyltransferase 1
chr7_+_100027404	2.588		MEPCE	methylphosphate capping enzyme
chr22_+_45559879	2.588		NUP50	nucleoporin 50kDa
chr7_-_139876718	2.574	NM_030647	JHDM1D	jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chrX_+_47420515	2.566	NM_001654	ARAF	v-raf murine sarcoma 3611 viral oncogene homolog
chr1_-_160232214	2.561		DCAF8	DDB1 and CUL4 associated factor 8
chr17_+_57970442	2.557	NM_003161	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr19_+_19144520	2.554		ARMC6	armadillo repeat containing 6
chr3_-_53079959	2.546		SFMBT1	Scm-like with four mbt domains 1
chr1_+_35734558	2.545	NM_005095	ZMYM4	zinc finger, MYM-type 4
chr3_+_44379590	2.545	NM_001029840	C3orf23	chromosome 3 open reading frame 23
chr7_-_6487573	2.543	NM_001142936 NM_139179	DAGLB	diacylglycerol lipase, beta
chr1_+_227127993	2.527		ADCK3	aarF domain containing kinase 3
chr18_-_5296013	2.518	NM_001143823 NM_003409	ZFP161	zinc finger protein 161 homolog (mouse)
chr19_+_7968765	2.518		MAP2K7	mitogen-activated protein kinase kinase 7
chr14_+_75229995	2.507	NM_019589	YLPM1	YLP motif containing 1
chr19_-_633526	2.504		POLRMT	polymerase (RNA) mitochondrial (DNA directed)
chr20_-_35580045	2.488		SAMHD1	SAM domain and HD domain 1
chr19_+_19144617	2.484		ARMC6	armadillo repeat containing 6
chr10_-_69834950	2.470		HERC4	hect domain and RLD 4
chr3_-_15140648	2.465		ZFYVE20	zinc finger, FYVE domain containing 20
chr9_+_110045565	2.460		RAD23B	RAD23 homolog B (S. cerevisiae)
chr21_-_38444814	2.457	NM_153681	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr10_-_127511795	2.456		UROS	uroporphyrinogen III synthase
chr17_+_18087091	2.448		ALKBH5	alkB, alkylation repair homolog 5 (E. coli)
chr1_-_229569839	2.431	NM_001100	ACTA1	actin, alpha 1, skeletal muscle
chr10_-_127511693	2.415		UROS	uroporphyrinogen III synthase
chr3_-_47517417	2.414	NM_012235	SCAP	SREBF chaperone
chr3_+_120315176	2.410		NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr8_-_145515014	2.403		BOP1	block of proliferation 1
chr16_-_90038869	2.401		CENPBD1	CENPB DNA-binding domains containing 1
chr1_-_84971882	2.399		GNG5	guanine nucleotide binding protein (G protein), gamma 5
chr5_-_88178964	2.393		MEF2C	myocyte enhancer factor 2C
chr10_-_74856656	2.384	NM_000917 NM_001017962 NM_001142595 NM_001142596	P4HA1	prolyl 4-hydroxylase, alpha polypeptide I
chr6_-_31620142	2.376	NM_001098534	BAG6	BCL2-associated athanogene 6
chr11_+_64073040	2.373	NM_004451	ESRRA	estrogen-related receptor alpha
chr16_+_84733611	2.366		USP10	ubiquitin specific peptidase 10
chr10_+_15139181	2.357	NM_001097590 NM_006414 NM_183005	RPP38	ribonuclease P/MRP 38kDa subunit
chr17_-_7155258	2.357	NM_015343	CTDNEP1	CTD nuclear envelope phosphatase 1
chr22_+_45559858	2.353		NUP50	nucleoporin 50kDa
chr2_-_223520762	2.351	NM_005687	FARSB	phenylalanyl-tRNA synthetase, beta subunit
chr9_-_139010716	2.341	NM_152833	C9orf69	chromosome 9 open reading frame 69
chr19_+_984316	2.339	NM_024100	WDR18	WD repeat domain 18
chr10_-_73611041	2.336		PSAP	prosaposin
chr6_-_36515060	2.328		STK38	serine/threonine kinase 38
chr21_-_38445389	2.324	NM_153682	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr2_-_33824294	2.321	NM_015475	FAM98A	family with sequence similarity 98, member A
chr1_+_197871681	2.319	NM_001024594	C1orf53	chromosome 1 open reading frame 53
chr14_+_102430897	2.317		DYNC1H1	dynein, cytoplasmic 1, heavy chain 1
chr3_+_137906080	2.313	NM_014154 NM_015396 NM_213654	ARMC8	armadillo repeat containing 8
chr19_+_18118921	2.312	NM_015683	ARRDC2	arrestin domain containing 2
chr9_-_139010379	2.300		C9orf69	chromosome 9 open reading frame 69
chr9_-_139981102	2.261		LOC100289341	uncharacterized LOC100289341
chr21_+_45553546	2.260		C21orf33	chromosome 21 open reading frame 33
chr14_+_101193313	2.259		DLK1	delta-like 1 homolog (Drosophila)
chr16_+_84733554	2.245	NM_005153	USP10	ubiquitin specific peptidase 10
chr16_+_27214806	2.239	NM_024773	JMJD5	jumonji domain containing 5
chr17_+_18086813	2.231	NM_017758	ALKBH5	alkB, alkylation repair homolog 5 (E. coli)
chr20_-_35580186	2.226	NM_015474	SAMHD1	SAM domain and HD domain 1
chr19_-_16582810	2.223		EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1
chr13_-_49107250	2.220	NM_001268	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_-_152684933	2.215		ARL5A	ADP-ribosylation factor-like 5A
chr2_+_207630111	2.212	NM_001136193 NM_001136194 NM_014929	FASTKD2	FAST kinase domains 2
chr8_+_23104153	2.206		CHMP7	charged multivesicular body protein 7
chr6_+_24403144	2.202	NM_020662	MRS2	MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr1_+_35734610	2.201		ZMYM4	zinc finger, MYM-type 4
chr21_-_34863779	2.201	NM_017833	DNAJC28	DnaJ (Hsp40) homolog, subfamily C, member 28
chr16_+_30969458	2.200
chr2_-_17935008	2.195		SMC6	structural maintenance of chromosomes 6
chr1_+_229407015	2.193		RAB4A	RAB4A, member RAS oncogene family

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.58	2.18e-08	GO:0044260	cellular macromolecule metabolic process
1.47	2.67e-06	GO:0043170	macromolecule metabolic process
1.38	6.20e-06	GO:0044237	cellular metabolic process
1.32	5.23e-05	GO:0008152	metabolic process
1.71	1.40e-04	GO:0090304	nucleic acid metabolic process
1.60	2.82e-04	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54	4.53e-04	GO:0034641	cellular nitrogen compound metabolic process
1.32	1.20e-03	GO:0044238	primary metabolic process
1.50	1.57e-03	GO:0006807	nitrogen compound metabolic process
1.77	2.11e-03	GO:0006996	organelle organization
1.59	2.13e-03	GO:0044267	cellular protein metabolic process
2.15	3.00e-03	GO:0046907	intracellular transport
2.04	7.04e-03	GO:0045184	establishment of protein localization
2.03	1.01e-02	GO:0015031	protein transport
1.88	1.53e-02	GO:0008104	protein localization
1.62	2.73e-02	GO:0006464	protein modification process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.24	1.41e-11	GO:0005622	intracellular
1.35	1.57e-11	GO:0043231	intracellular membrane-bounded organelle
1.25	1.85e-11	GO:0044424	intracellular part
1.35	1.87e-11	GO:0043227	membrane-bounded organelle
1.50	6.34e-10	GO:0005634	nucleus
1.27	8.10e-09	GO:0043229	intracellular organelle
1.27	1.07e-08	GO:0043226	organelle
1.68	2.30e-07	GO:0043234	protein complex
1.60	2.60e-07	GO:0032991	macromolecular complex
1.70	8.64e-06	GO:0031974	membrane-enclosed lumen
1.72	1.04e-05	GO:0070013	intracellular organelle lumen
1.39	1.06e-05	GO:0044446	intracellular organelle part
1.73	1.17e-05	GO:0044428	nuclear part
1.97	1.48e-05	GO:0005654	nucleoplasm
1.68	2.79e-05	GO:0043233	organelle lumen
1.37	3.50e-05	GO:0044422	organelle part
1.75	9.52e-05	GO:0031981	nuclear lumen
1.90	1.08e-04	GO:0005739	mitochondrion
3.42	2.76e-04	GO:0005813	centrosome
4.16	1.85e-03	GO:0044455	mitochondrial membrane part
2.10	2.29e-03	GO:0044451	nucleoplasm part
2.13	2.90e-03	GO:0044429	mitochondrial part
4.72	5.28e-03	GO:0046930	pore complex
1.20	1.21e-02	GO:0005737	cytoplasm
1.98	1.90e-02	GO:0031967	organelle envelope
1.26	2.03e-02	GO:0044444	cytoplasmic part
1.94	2.73e-02	GO:0031975	envelope
2.42	3.55e-02	GO:0005815	microtubule organizing center

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.34	4.74e-07	GO:0005515	protein binding
8.02	4.30e-04	GO:0003899	DNA-directed RNA polymerase activity
8.02	4.30e-04	GO:0034062	RNA polymerase activity
6.74	2.20e-02	GO:0043130	ubiquitin binding
1.12	2.26e-02	GO:0005488	binding
1.28	2.90e-02	GO:0003824	catalytic activity
6.40	3.12e-02	GO:0032182	small conjugating protein binding