Motif ID: NRF1.p2

Z-value: 5.189


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NRF1hg19_v1_chr7_+_129251579_1292516450.154.0e-01Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_260092 8.439 NM_001013672
 C17orf97
chromosome 17 open reading frame 97
chr22_-_19279183 7.720 NM_001835
NM_007098
 CLTCL1

clathrin, heavy chain-like 1

chr1_+_231473681 7.031 NM_001010984
NM_032018
 C1orf124

chromosome 1 open reading frame 124

chr1_+_231473773 6.323 C1orf124
chromosome 1 open reading frame 124
chr6_-_33679435 5.644 C6orf125
chromosome 6 open reading frame 125
chr6_-_33679501 5.556 NM_032340
 C6orf125
chromosome 6 open reading frame 125
chr17_-_7518124 5.545 NM_004860
 FXR2
fragile X mental retardation, autosomal homolog 2
chr16_+_50099907 5.496 HEATR3
HEAT repeat containing 3
chr16_+_50099880 5.221 NM_182922
 HEATR3
HEAT repeat containing 3
chr12_-_54070108 5.017 NM_005176
 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr19_-_46405854 4.882 NM_001012643
 MYPOP
Myb-related transcription factor, partner of profilin
chr6_+_30614815 4.865 NM_001109938
NM_001161376
NM_145029
 C6orf136


chromosome 6 open reading frame 136


chr8_+_42249383 4.657 VDAC3
voltage-dependent anion channel 3
chr7_-_44365019 4.652 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
 CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr1_+_167189948 4.542 NM_001198786
NM_002697
 POU2F1

POU class 2 homeobox 1

chr4_-_56412968 4.399 NM_004898
 CLOCK
clock homolog (mouse)
chr1_-_231473478 4.302 NM_175876
 EXOC8
exocyst complex component 8
chr6_+_111408780 4.231 NM_018593
 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr16_+_28565279 4.192 CCDC101
coiled-coil domain containing 101
chr1_-_202858225 4.144 NM_002871
 RABIF
RAB interacting factor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
2.15 3.00e-03 GO:0046907 intracellular transport
2.04 7.04e-03 GO:0045184 establishment of protein localization
2.03 1.01e-02 GO:0015031 protein transport
1.88 1.53e-02 GO:0008104 protein localization
1.77 2.11e-03 GO:0006996 organelle organization
1.71 1.40e-04 GO:0090304 nucleic acid metabolic process
1.62 2.73e-02 GO:0006464 protein modification process
1.60 2.82e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 2.13e-03 GO:0044267 cellular protein metabolic process
1.58 2.18e-08 GO:0044260 cellular macromolecule metabolic process
1.54 4.53e-04 GO:0034641 cellular nitrogen compound metabolic process
1.50 1.57e-03 GO:0006807 nitrogen compound metabolic process
1.47 2.67e-06 GO:0043170 macromolecule metabolic process
1.38 6.20e-06 GO:0044237 cellular metabolic process
1.32 5.23e-05 GO:0008152 metabolic process
1.32 1.20e-03 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
Enrichment   P-value GO Accession GO Term
4.72 5.28e-03 GO:0046930 pore complex
4.16 1.85e-03 GO:0044455 mitochondrial membrane part
3.42 2.76e-04 GO:0005813 centrosome
2.42 3.55e-02 GO:0005815 microtubule organizing center
2.13 2.90e-03 GO:0044429 mitochondrial part
2.10 2.29e-03 GO:0044451 nucleoplasm part
1.98 1.90e-02 GO:0031967 organelle envelope
1.97 1.48e-05 GO:0005654 nucleoplasm
1.94 2.73e-02 GO:0031975 envelope
1.90 1.08e-04 GO:0005739 mitochondrion
1.75 9.52e-05 GO:0031981 nuclear lumen
1.73 1.17e-05 GO:0044428 nuclear part
1.72 1.04e-05 GO:0070013 intracellular organelle lumen
1.70 8.64e-06 GO:0031974 membrane-enclosed lumen
1.68 2.30e-07 GO:0043234 protein complex
1.68 2.79e-05 GO:0043233 organelle lumen
1.60 2.60e-07 GO:0032991 macromolecular complex
1.50 6.34e-10 GO:0005634 nucleus
1.39 1.06e-05 GO:0044446 intracellular organelle part
1.37 3.50e-05 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
8.02 4.30e-04 GO:0003899 DNA-directed RNA polymerase activity
8.02 4.30e-04 GO:0034062 RNA polymerase activity
6.74 2.20e-02 GO:0043130 ubiquitin binding
6.40 3.12e-02 GO:0032182 small conjugating protein binding
1.34 4.74e-07 GO:0005515 protein binding
1.28 2.90e-02 GO:0003824 catalytic activity
1.12 2.26e-02 GO:0005488 binding