Motif ID: ONECUT1,2.p2

Z-value: 1.450


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
ONECUT1 3175 one cut homeobox 1
ONECUT2 9480 one cut homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ONECUT2hg19_v1_chr18_+_55102777_551029540.631.2e-04Click!
ONECUT1hg19_v1_chr15_-_53082087_530823020.621.5e-04Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_29171729 5.799 NM_000371
 TTR
transthyretin
chr6_+_30130982 5.620 NM_033229
 TRIM15
tripartite motif containing 15
chr7_+_151653463 5.496 NM_145292
 GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr1_+_159557615 5.306 NM_001639
 APCS
amyloid P component, serum
chr4_-_155511838 4.778 NM_000508
NM_021871
 FGA

fibrinogen alpha chain

chr4_-_69536314 4.751 NM_001076
 UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr4_+_156824846 4.683 NM_005651
 TDO2
tryptophan 2,3-dioxygenase
chr7_-_100239136 4.667 NM_003227
 TFR2
transferrin receptor 2
chr2_+_135596185 4.193 NM_138326
 ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr10_+_7745325 4.041 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_63137260 4.015 NM_080866
 SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr1_+_63063186 3.957 NM_014495
 ANGPTL3
angiopoietin-like 3
chr10_+_7745341 3.923 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745284 3.855 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745229 3.829 NM_002216
 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745354 3.758 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_170744767 3.756 NM_000340
 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr1_-_67594219 3.504 NM_001013674
 C1orf141
chromosome 1 open reading frame 141
chr14_+_100789674 2.997 NM_207117
 SLC25A47
solute carrier family 25, member 47
chr1_+_196946666 2.973 NM_030787
 CFHR5
complement factor H-related 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
117.28 5.16e-04 GO:0031639 plasminogen activation
52.13 3.82e-04 GO:0051917 regulation of fibrinolysis
52.13 1.06e-02 GO:0031638 zymogen activation
36.09 3.54e-02 GO:0006957 complement activation, alternative pathway
22.35 1.46e-02 GO:0030195 negative regulation of blood coagulation
21.58 1.69e-02 GO:0050819 negative regulation of coagulation
20.06 2.39e-03 GO:0030193 regulation of blood coagulation
18.62 3.48e-03 GO:0050818 regulation of coagulation
17.95 5.95e-05 GO:0072376 protein activation cascade
16.30 6.80e-03 GO:0061041 regulation of wound healing
5.72 4.11e-02 GO:0008202 steroid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
5.35 1.36e-02 GO:0005792 microsome
5.18 1.71e-02 GO:0042598 vesicular fraction
3.16 8.07e-03 GO:0005615 extracellular space
2.14 1.37e-02 GO:0005576 extracellular region
1.48 3.69e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
78.19 3.43e-02 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
78.19 3.43e-02 GO:0034875 caffeine oxidase activity
22.35 4.08e-03 GO:0015020 glucuronosyltransferase activity
14.22 2.50e-02 GO:0043498 cell surface binding