Motif ID: PAX2.p2

Z-value: 2.239


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX2hg19_v1_chr10_+_102505337_102505467-0.467.4e-03Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_18122850 3.413 NM_198586
 NHLRC1
NHL repeat containing 1
chr16_-_46782104 3.409 NM_182493
 MYLK3
myosin light chain kinase 3
chr2_-_179659680 3.131 TTN
titin
chr14_-_65289812 3.112 NM_000347
NM_001024858
 SPTB

spectrin, beta, erythrocytic

chr9_+_103340335 3.080 NM_001018116
 MURC
muscle-related coiled-coil protein
chr1_+_6052758 2.819 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr5_-_90610218 2.694 LOC100505994
uncharacterized LOC100505994
chr17_+_33474835 2.653 NM_001033576
NM_173167
 UNC45B

unc-45 homolog B (C. elegans)

chr1_+_6052699 2.484 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr18_+_32621299 2.412 NM_014268
 MAPRE2
microtubule-associated protein, RP/EB family, member 2
chrX_+_10124984 2.317 NM_001830
 CLCN4
chloride channel 4
chr17_+_7348362 2.219 NM_000747
 CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr1_+_154377847 2.128 IL6R
interleukin 6 receptor
chr3_+_50654600 2.079 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr1_+_154378044 2.057 IL6R
interleukin 6 receptor
chr1_+_236849753 1.983 NM_001103
 ACTN2
actinin, alpha 2
chr3_+_50654589 1.974 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr22_+_35695872 1.961 TOM1
target of myb1 (chicken)
chr4_+_106068009 1.933 TET2
tet methylcytosine dioxygenase 2
chr3_+_50654558 1.891 NM_001243925
NM_004635
 MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
16.82 1.25e-03 GO:0006096 glycolysis
16.66 1.03e-02 GO:0006941 striated muscle contraction
12.98 5.88e-03 GO:0006007 glucose catabolic process
10.42 2.12e-02 GO:0019320 hexose catabolic process
10.00 2.68e-02 GO:0046365 monosaccharide catabolic process
7.26 1.34e-02 GO:0006006 glucose metabolic process
6.25 3.95e-02 GO:0006936 muscle contraction
4.07 3.70e-02 GO:0006091 generation of precursor metabolites and energy
2.99 3.51e-03 GO:0006793 phosphorus metabolic process
2.99 3.51e-03 GO:0006796 phosphate metabolic process
1.92 1.15e-02 GO:0051234 establishment of localization
1.90 1.91e-02 GO:0006810 transport
1.88 3.55e-03 GO:0051179 localization
1.55 6.45e-03 GO:0044237 cellular metabolic process
1.46 1.68e-02 GO:0008152 metabolic process
1.32 2.17e-04 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
11.33 1.74e-05 GO:0030017 sarcomere
10.11 2.36e-02 GO:0005746 mitochondrial respiratory chain
9.82 5.95e-05 GO:0044449 contractile fiber part
9.57 7.45e-05 GO:0030016 myofibril
9.35 3.43e-02 GO:0070469 respiratory chain
9.03 1.23e-04 GO:0043292 contractile fiber
6.90 3.78e-03 GO:0005769 early endosome
4.26 4.90e-02 GO:0000323 lytic vacuole
4.26 4.90e-02 GO:0005764 lysosome
3.81 6.75e-03 GO:0031966 mitochondrial membrane
3.65 1.06e-02 GO:0005740 mitochondrial envelope
3.45 3.50e-02 GO:0005768 endosome
3.11 1.01e-02 GO:0044429 mitochondrial part
2.96 1.80e-02 GO:0031967 organelle envelope
2.91 2.21e-02 GO:0031975 envelope
2.59 1.13e-03 GO:0005739 mitochondrion
1.79 5.20e-08 GO:0044444 cytoplasmic part
1.52 1.19e-02 GO:0044422 organelle part
1.50 5.93e-06 GO:0005737 cytoplasm
1.49 2.99e-02 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
82.18 3.72e-02 GO:0004332 fructose-bisphosphate aldolase activity
2.59 3.83e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.61 1.37e-03 GO:0003824 catalytic activity