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Motif ID: PAX2.p2

Z-value: 2.239

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_18122850	3.413	NM_198586	NHLRC1	NHL repeat containing 1
chr16_-_46782104	3.409	NM_182493	MYLK3	myosin light chain kinase 3
chr2_-_179659680	3.131		TTN	titin
chr14_-_65289812	3.112	NM_000347 NM_001024858	SPTB	spectrin, beta, erythrocytic
chr9_+_103340335	3.080	NM_001018116	MURC	muscle-related coiled-coil protein
chr1_+_6052758	2.819		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr5_-_90610218	2.694		LOC100505994	uncharacterized LOC100505994
chr17_+_33474835	2.653	NM_001033576 NM_173167	UNC45B	unc-45 homolog B (C. elegans)
chr1_+_6052699	2.484		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr18_+_32621299	2.412	NM_014268	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chrX_+_10124984	2.317	NM_001830	CLCN4	chloride channel 4
chr17_+_7348362	2.219	NM_000747	CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)
chr1_+_154377847	2.128		IL6R	interleukin 6 receptor
chr3_+_50654600	2.079		MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr1_+_154378044	2.057		IL6R	interleukin 6 receptor
chr1_+_236849753	1.983	NM_001103	ACTN2	actinin, alpha 2
chr3_+_50654589	1.974		MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr22_+_35695872	1.961		TOM1	target of myb1 (chicken)
chr4_+_106068009	1.933		TET2	tet methylcytosine dioxygenase 2
chr3_+_50654558	1.891	NM_001243925 NM_004635	MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr14_+_24584009	1.881		DCAF11	DDB1 and CUL4 associated factor 11
chr14_-_23904849	1.880	NM_000257	MYH7	myosin, heavy chain 7, cardiac muscle, beta
chr6_-_90121966	1.878	NM_021244	RRAGD	Ras-related GTP binding D
chr11_-_126081532	1.876	NM_001144827 NM_032795	RPUSD4	RNA pseudouridylate synthase domain containing 4
chr10_-_3827205	1.871		KLF6	Kruppel-like factor 6
chr14_+_24584321	1.836		DCAF11	DDB1 and CUL4 associated factor 11
chr2_+_86947570	1.835		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr16_-_4588738	1.833	NM_001199055 NM_001199056 NM_013399	C16orf5	chromosome 16 open reading frame 5
chr12_+_56109851	1.829		BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1
chrX_-_21676416	1.823	NM_153270	KLHL34	kelch-like 34 (Drosophila)
chr20_+_44520203	1.822		CTSA	cathepsin A
chr10_+_88428167	1.815	NM_001171610	LDB3	LIM domain binding 3
chr13_-_114107838	1.795	NM_138430	ADPRHL1	ADP-ribosylhydrolase like 1
chr1_-_100643770	1.794	NM_144620	LRRC39	leucine rich repeat containing 39
chr14_+_24584467	1.787	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr16_-_5083913	1.776		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr5_+_133706869	1.774	NM_003337	UBE2B	ubiquitin-conjugating enzyme E2B
chr11_-_36310934	1.771		COMMD9	COMM domain containing 9
chr13_+_48877886	1.751		RB1	retinoblastoma 1
chr11_-_119252267	1.731		USP2	ubiquitin specific peptidase 2
chr9_-_97356007	1.730	NM_003837	FBP2	fructose-1,6-bisphosphatase 2
chr9_-_139922595	1.695		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr4_-_164534656	1.690	NM_017923	MARCH1	membrane-associated ring finger (C3HC4) 1
chr6_-_86352650	1.681		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_+_148206155	1.678	NM_000024	ADRB2	adrenergic, beta-2-, receptor, surface
chr14_-_94442894	1.665		ASB2	ankyrin repeat and SOCS box containing 2
chrX_+_30671602	1.653		GK	glycerol kinase
chr12_-_46384317	1.629		SCAF11	SR-related CTD-associated factor 11
chr4_+_144106083	1.626		USP38	ubiquitin specific peptidase 38
chr1_+_154377668	1.622	NM_000565 NM_001206866 NM_181359	IL6R	interleukin 6 receptor
chr13_-_110438896	1.620	NM_003749	IRS2	insulin receptor substrate 2
chrX_+_100663213	1.601		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr12_+_105501537	1.598		KIAA1033	KIAA1033
chr12_+_56109817	1.594	NM_001487	BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1
chr12_+_105501545	1.593		KIAA1033	KIAA1033
chr10_+_23728197	1.581	NM_001145373	OTUD1	OTU domain containing 1
chr12_-_64616032	1.571	NM_152440	C12orf66	chromosome 12 open reading frame 66
chr1_+_222885895	1.567	NM_144695	BROX	BRO1 domain and CAAX motif containing
chr10_+_18240767	1.565	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chr8_+_67039130	1.548	NM_033058 NM_184085 NM_184086 NM_184087	TRIM55	tripartite motif containing 55
chr14_-_68283293	1.540	NM_015346	ZFYVE26	zinc finger, FYVE domain containing 26
chrX_+_100663229	1.519		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr19_-_40854410	1.518		C19orf47	chromosome 19 open reading frame 47
chr12_+_56109832	1.507		BLOC1S1-RDH5 BLOC1S1	BLOC1S1-RDH5 readthrough biogenesis of lysosomal organelles complex-1, subunit 1
chr5_-_150138081	1.507	NM_001135644	DCTN4	dynactin 4 (p62)
chr13_+_48878025	1.504		RB1	retinoblastoma 1
chr3_+_113465901	1.503		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr7_+_149571029	1.494		ATP6V0E2	ATPase, H+ transporting V0 subunit e2
chr11_-_113746205	1.482	NM_020886	USP28	ubiquitin specific peptidase 28
chr13_+_48877950	1.476		RB1	retinoblastoma 1
chr17_-_26903854	1.471		ALDOC	aldolase C, fructose-bisphosphate
chr16_-_5083933	1.471	NM_016256	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr5_-_150138554	1.465	NM_001135643 NM_016221	DCTN4	dynactin 4 (p62)
chrX_-_153640358	1.452	NM_001009932 NM_001009933 NM_001009934	DNASE1L1	deoxyribonuclease I-like 1
chr13_-_50366543	1.446		KPNA3	karyopherin alpha 3 (importin alpha 4)
chrX_+_100663205	1.445		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_+_207226594	1.443	NM_001018053 NM_006212	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr12_-_123849374	1.425		SBNO1	strawberry notch homolog 1 (Drosophila)
chr12_+_72148653	1.423	NM_014999	RAB21	RAB21, member RAS oncogene family
chr5_+_110074708	1.410		SLC25A46	solute carrier family 25, member 46
chr5_+_110074740	1.404	NM_138773	SLC25A46	solute carrier family 25, member 46
chr1_+_161284165	1.397	NM_001035511 NM_001035512 NM_001035513 NM_003001	SDHC	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr1_-_198906536	1.393		LOC100131234	familial acute myelogenous leukemia related factor
chr11_-_36310974	1.382	NM_001101653 NM_014186	COMMD9	COMM domain containing 9
chr6_+_64282449	1.376		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr6_-_53530505	1.374	NM_001003760	KLHL31	kelch-like 31 (Drosophila)
chr14_+_55738102	1.364		FBXO34	F-box protein 34
chrX_+_47420515	1.362	NM_001654	ARAF	v-raf murine sarcoma 3611 viral oncogene homolog
chr16_+_57662301	1.359	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr1_-_24434927	1.359		MYOM3	myomesin family, member 3
chr12_-_76953526	1.355		OSBPL8	oxysterol binding protein-like 8
chr3_+_50654868	1.348		MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr1_+_36690038	1.344		THRAP3	thyroid hormone receptor associated protein 3
chr19_-_40854283	1.341	NM_178830	C19orf47	chromosome 19 open reading frame 47
chr7_-_44365019	1.340	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr6_-_86352656	1.338		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_-_123849755	1.337		SBNO1	strawberry notch homolog 1 (Drosophila)
chr6_-_86352696	1.337		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr16_+_28996146	1.337	NM_001014989	LAT	linker for activation of T cells
chr20_+_44519924	1.334		CTSA	cathepsin A
chr13_-_50366703	1.333		KPNA3	karyopherin alpha 3 (importin alpha 4)
chr8_-_126104007	1.331		KIAA0196	KIAA0196
chr17_-_26903926	1.324	NM_005165	ALDOC	aldolase C, fructose-bisphosphate
chr3_+_42727010	1.322	NM_152393	KBTBD5	kelch repeat and BTB (POZ) domain containing 5
chr5_-_133706717	1.316		CDKL3	cyclin-dependent kinase-like 3
chr8_-_126104004	1.315		KIAA0196	KIAA0196
chr11_-_119252364	1.315	NM_001243759 NM_004205	USP2	ubiquitin specific peptidase 2
chr14_+_77564570	1.314	NM_033426	KIAA1737	KIAA1737
chr14_+_68086633	1.311		ARG2	arginase, type II
chr1_-_162381805	1.300	NM_053282	SH2D1B	SH2 domain containing 1B
chr2_+_27505296	1.298	NM_032546 NM_187841	TRIM54	tripartite motif containing 54
chr8_-_126103926	1.297		KIAA0196	KIAA0196
chr2_+_75061234	1.295		HK2	hexokinase 2
chr2_+_54342409	1.294	NM_138448	ACYP2	acylphosphatase 2, muscle type
chr12_-_122750954	1.292		VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr17_+_33570079	1.292	NM_144975	SLFN5	schlafen family member 5
chr8_-_126104021	1.289		KIAA0196	KIAA0196
chr9_+_120466625	1.288		TLR4	toll-like receptor 4
chr18_+_54318561	1.287	NM_015285 NM_052834	WDR7	WD repeat domain 7
chr11_+_121323065	1.286		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr19_-_38916801	1.281	NM_001146202 NM_001146203 NM_001146204 NM_001146205 NM_001146206 NM_001146207 NM_170604	RASGRP4	RAS guanyl releasing protein 4
chr2_+_86947429	1.278		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr15_+_90544608	1.276	NM_198526	ZNF710	zinc finger protein 710
chr12_+_112856756	1.274		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chrX_+_30671456	1.272	NM_000167 NM_001128127 NM_001205019 NM_203391	GK	glycerol kinase
chr14_+_64971226	1.270	NM_001123329 NM_014950	ZBTB1	zinc finger and BTB domain containing 1
chr11_-_6640645	1.270		TPP1	tripeptidyl peptidase I
chr10_-_76868853	1.262	NM_001007271 NM_001007272 NM_001007273	DUSP13	dual specificity phosphatase 13
chr2_-_240964807	1.253	NM_004544	NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr11_-_6640578	1.251		TPP1	tripeptidyl peptidase I
chr15_-_75230354	1.248		COX5A	cytochrome c oxidase subunit Va
chr17_+_46019022	1.244		PNPO	pyridoxamine 5'-phosphate oxidase
chr22_+_26138110	1.242	NM_032608	MYO18B	myosin XVIIIB
chr6_+_160390128	1.241	NM_000876	IGF2R	insulin-like growth factor 2 receptor
chr14_-_94443065	1.234	NM_001202429	ASB2	ankyrin repeat and SOCS box containing 2
chrY_-_15591799	1.233		UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
chrX_-_106960028	1.224		TSC22D3	TSC22 domain family, member 3
chr11_-_6640644	1.221		TPP1	tripeptidyl peptidase I
chrX_+_48555135	1.216		SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr16_+_31119730	1.215		BCKDK	branched chain ketoacid dehydrogenase kinase
chrX_+_77359768	1.215		PGK1	phosphoglycerate kinase 1
chr7_+_140396463	1.214	NM_004546	NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr1_+_77747602	1.212	NM_174858	AK5	adenylate kinase 5
chr6_-_31745048	1.205	NM_025258	C6orf27	chromosome 6 open reading frame 27
chr6_-_90121911	1.204		RRAGD	Ras-related GTP binding D
chr2_-_211179765	1.200	NM_079420	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr16_+_30077146	1.199		ALDOA	aldolase A, fructose-bisphosphate
chr1_+_6052357	1.198	NM_001199861	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr2_-_240964717	1.197		NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr18_+_77155943	1.190		NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_+_64282429	1.189		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr1_+_117544371	1.187	NM_004258	CD101	CD101 molecule
chr6_+_29913400	1.184
chr8_-_71581419	1.175	NM_016027	LACTB2	lactamase, beta 2
chr6_-_86352564	1.175	NM_001159674 NM_001253771	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_112856701	1.172		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chr11_-_85779821	1.167		PICALM	phosphatidylinositol binding clathrin assembly protein
chr16_+_30077120	1.163		ALDOA	aldolase A, fructose-bisphosphate
chr5_+_43603312	1.161		NNT	nicotinamide nucleotide transhydrogenase
chr19_-_48018163	1.158		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr5_-_168006413	1.153	NM_024594	PANK3	pantothenate kinase 3
chr2_-_220042731	1.133		CNPPD1	cyclin Pas1/PHO80 domain containing 1
chr2_-_176866925	1.126	NM_030650	KIAA1715	KIAA1715
chr19_-_48018277	1.122		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_9599546	1.117		SLC25A33	solute carrier family 25, member 33
chr10_-_3827418	1.116	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr12_+_56660724	1.113		COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr8_-_66754276	1.113		PDE7A	phosphodiesterase 7A
chr8_-_126104045	1.099	NM_014846	KIAA0196	KIAA0196
chr22_+_18121540	1.098		BCL2L13	BCL2-like 13 (apoptosis facilitator)
chr5_-_168006297	1.097		PANK3	pantothenate kinase 3
chr20_+_44519965	1.096		CTSA	cathepsin A
chr8_-_126103873	1.095		KIAA0196	KIAA0196
chr5_+_67586466	1.091	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_6640661	1.091	NM_000391	TPP1	tripeptidyl peptidase I
chr1_-_6662681	1.090		KLHL21	kelch-like 21 (Drosophila)
chr16_+_31119748	1.086		BCKDK	branched chain ketoacid dehydrogenase kinase
chr1_-_113498828	1.085	NM_003051	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr12_-_46384346	1.084		SCAF11	SR-related CTD-associated factor 11
chr20_+_58515408	1.084	NM_001190827 NM_022106	C20orf177	chromosome 20 open reading frame 177
chr3_+_158519888	1.083		MFSD1	major facilitator superfamily domain containing 1
chr1_-_113498615	1.081	NM_001166496	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr1_+_174843523	1.080	NM_001243763	RABGAP1L	RAB GTPase activating protein 1-like
chr6_-_86352635	1.080	NM_001159673	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_16035287	1.079	NM_007178	STRAP	serine/threonine kinase receptor associated protein
chr22_+_35695792	1.069	NM_001135730 NM_001135732 NM_005488	TOM1	target of myb1 (chicken)
chr12_+_56661026	1.069	NM_001099337	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr8_-_33457279	1.069		DUSP26	dual specificity phosphatase 26 (putative)
chr16_+_30076993	1.064	NM_001243177 NM_184041	ALDOA	aldolase A, fructose-bisphosphate
chr1_+_10092990	1.062	NM_001105562 NM_006048	UBE4B	ubiquitination factor E4B
chr6_+_155538096	1.058	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr11_+_107879985	1.055		CUL5	cullin 5
chr12_+_56660913	1.051		COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr16_-_69419540	1.049		TERF2	telomeric repeat binding factor 2
chr11_-_82782870	1.046		RAB30	RAB30, member RAS oncogene family
chr10_+_11060105	1.045		CELF2	CUGBP, Elav-like family member 2
chr12_+_50898768	1.043		DIP2B	DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr13_+_48877900	1.043		RB1	retinoblastoma 1
chr21_+_38739193	1.041		DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr8_+_98656428	1.037		MTDH	metadherin

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.32	2.17e-04	GO:0009987	cellular process
16.82	1.25e-03	GO:0006096	glycolysis
2.99	3.51e-03	GO:0006793	phosphorus metabolic process
2.99	3.51e-03	GO:0006796	phosphate metabolic process
1.88	3.55e-03	GO:0051179	localization
12.98	5.88e-03	GO:0006007	glucose catabolic process
1.55	6.45e-03	GO:0044237	cellular metabolic process
16.66	1.03e-02	GO:0006941	striated muscle contraction
1.92	1.15e-02	GO:0051234	establishment of localization
7.26	1.34e-02	GO:0006006	glucose metabolic process
1.46	1.68e-02	GO:0008152	metabolic process
1.90	1.91e-02	GO:0006810	transport
10.42	2.12e-02	GO:0019320	hexose catabolic process
10.00	2.68e-02	GO:0046365	monosaccharide catabolic process
4.07	3.70e-02	GO:0006091	generation of precursor metabolites and energy
6.25	3.95e-02	GO:0006936	muscle contraction

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.79	5.20e-08	GO:0044444	cytoplasmic part
1.50	5.93e-06	GO:0005737	cytoplasm
11.33	1.74e-05	GO:0030017	sarcomere
9.82	5.95e-05	GO:0044449	contractile fiber part
9.57	7.45e-05	GO:0030016	myofibril
9.03	1.23e-04	GO:0043292	contractile fiber
2.59	1.13e-03	GO:0005739	mitochondrion
1.27	1.83e-03	GO:0044424	intracellular part
6.90	3.78e-03	GO:0005769	early endosome
3.81	6.75e-03	GO:0031966	mitochondrial membrane
1.24	9.63e-03	GO:0005622	intracellular
3.11	1.01e-02	GO:0044429	mitochondrial part
3.65	1.06e-02	GO:0005740	mitochondrial envelope
1.52	1.19e-02	GO:0044422	organelle part
2.96	1.80e-02	GO:0031967	organelle envelope
2.91	2.21e-02	GO:0031975	envelope
10.11	2.36e-02	GO:0005746	mitochondrial respiratory chain
1.49	2.99e-02	GO:0044446	intracellular organelle part
9.35	3.43e-02	GO:0070469	respiratory chain
3.45	3.50e-02	GO:0005768	endosome
4.26	4.90e-02	GO:0000323	lytic vacuole
4.26	4.90e-02	GO:0005764	lysosome

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.61	1.37e-03	GO:0003824	catalytic activity
82.18	3.72e-02	GO:0004332	fructose-bisphosphate aldolase activity
2.59	3.83e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups