Motif ID: PAX4.p2

Z-value: 1.418


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX4hg19_v1_chr7_-_127255574_127255779-0.192.9e-01Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_80267972 7.357 CD36
CD36 molecule (thrombospondin receptor)
chr7_+_80267922 7.259 CD36
CD36 molecule (thrombospondin receptor)
chr7_+_80267782 6.051 NM_000072
NM_001001548
 CD36

CD36 molecule (thrombospondin receptor)

chr1_+_101702561 4.037 S1PR1
sphingosine-1-phosphate receptor 1
chr1_-_153348057 3.711 NM_005621
 S100A12
S100 calcium binding protein A12
chr1_+_101702304 2.875 NM_001400
 S1PR1
sphingosine-1-phosphate receptor 1
chr19_-_54784922 2.192 NM_001080978
NM_005874
 LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

chr12_-_16759531 1.959 NM_018640
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr20_-_23062786 1.936 CD93
CD93 molecule
chr19_+_42300521 1.884 NM_001815
 CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr19_-_54824343 1.853 NM_021250
NM_181879
NM_181985
NM_181986
 LILRA5



leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5



chr10_-_27703178 1.781 NM_001034842
 PTCHD3
patched domain containing 3
chrX_+_71130619 1.766 NM_001013627
 NHSL2
NHS-like 2
chr9_-_20622476 1.736 NM_004529
 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_-_86290333 1.646 NM_001128829
NM_001128830
NM_001128831
NM_001738
 CA1



carbonic anhydrase I



chr9_-_20622433 1.640 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_+_219125737 1.633 NM_001077191
NM_001077194
NM_170699
 GPBAR1


G protein-coupled bile acid receptor 1


chr8_-_82395401 1.517 NM_001442
 FABP4
fatty acid binding protein 4, adipocyte
chr1_-_160681552 1.516 NM_001778
 CD48
CD48 molecule
chr3_+_42530790 1.485 NM_001251882
 VIPR1
vasoactive intestinal peptide receptor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
27.82 3.80e-03 GO:0006968 cellular defense response
8.18 2.52e-02 GO:0019932 second-messenger-mediated signaling
6.12 9.05e-05 GO:0006952 defense response
4.06 6.45e-03 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
62.57 2.71e-02 GO:0043209 myelin sheath
2.26 1.25e-05 GO:0031224 intrinsic to membrane
2.22 3.79e-05 GO:0016021 integral to membrane
1.94 4.53e-04 GO:0044425 membrane part
1.71 2.67e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
125.11 5.81e-03 GO:0016494 C-X-C chemokine receptor activity
107.24 8.13e-03 GO:0019958 C-X-C chemokine binding
56.31 1.08e-03 GO:0001637 G-protein chemoattractant receptor activity
56.31 1.08e-03 GO:0004950 chemokine receptor activity
51.19 1.45e-03 GO:0019956 chemokine binding
20.87 2.08e-05 GO:0019955 cytokine binding
3.83 6.58e-05 GO:0004872 receptor activity
3.82 2.15e-03 GO:0004888 transmembrane receptor activity
3.33 1.91e-04 GO:0004871 signal transducer activity
3.33 1.91e-04 GO:0060089 molecular transducer activity