• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: PAX4.p2

Z-value: 1.418

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_80267972	7.357		CD36	CD36 molecule (thrombospondin receptor)
chr7_+_80267922	7.259		CD36	CD36 molecule (thrombospondin receptor)
chr7_+_80267782	6.051	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr1_+_101702561	4.037		S1PR1	sphingosine-1-phosphate receptor 1
chr1_-_153348057	3.711	NM_005621	S100A12	S100 calcium binding protein A12
chr1_+_101702304	2.875	NM_001400	S1PR1	sphingosine-1-phosphate receptor 1
chr19_-_54784922	2.192	NM_001080978 NM_005874	LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr12_-_16759531	1.959	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr20_-_23062786	1.936		CD93	CD93 molecule
chr19_+_42300521	1.884	NM_001815	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3
chr19_-_54824343	1.853	NM_021250 NM_181879 NM_181985 NM_181986	LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr10_-_27703178	1.781	NM_001034842	PTCHD3	patched domain containing 3
chrX_+_71130619	1.766	NM_001013627	NHSL2	NHS-like 2
chr9_-_20622476	1.736	NM_004529	MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_-_86290333	1.646	NM_001128829 NM_001128830 NM_001128831 NM_001738	CA1	carbonic anhydrase I
chr9_-_20622433	1.640		MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_+_219125737	1.633	NM_001077191 NM_001077194 NM_170699	GPBAR1	G protein-coupled bile acid receptor 1
chr8_-_82395401	1.517	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr1_-_160681552	1.516	NM_001778	CD48	CD48 molecule
chr3_+_42530790	1.485	NM_001251882	VIPR1	vasoactive intestinal peptide receptor 1
chr8_-_21771111	1.469	NM_003974	DOK2	docking protein 2, 56kDa
chr19_+_55141907	1.382	NM_001081638 NM_001081639 NM_001081637	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr11_-_124622133	1.377		VSIG2	V-set and immunoglobulin domain containing 2
chr4_-_84030995	1.374	NM_001130716	PLAC8	placenta-specific 8
chr6_+_31554475	1.364	NM_205837	LST1	leukocyte specific transcript 1
chr9_+_79115548	1.359	NM_001097636	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2
chr22_-_31688329	1.334	NM_001135911 NM_052880	PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr17_-_46799879	1.310	NM_032391	PRAC	prostate cancer susceptibility candidate
chr11_+_1874199	1.310	NM_002339	LSP1	lymphocyte-specific protein 1
chr8_-_13133956	1.307
chr7_-_135613197	1.287		LUZP6	leucine zipper protein 6
chr12_-_16760935	1.273	NM_001001395 NM_001243609	LMO3	LIM domain only 3 (rhombotin-like 2)
chr9_-_85882093	1.249	NM_001244962	FRMD3	FERM domain containing 3
chr1_+_12123433	1.249	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr18_-_64271215	1.245	NM_021153	CDH19	cadherin 19, type 2
chr2_-_136873740	1.236	NM_001008540	CXCR4	chemokine (C-X-C motif) receptor 4
chr11_-_58980321	1.229	NM_001039396	MPEG1	macrophage expressed 1
chr7_-_86595203	1.211	NM_152748	KIAA1324L	KIAA1324-like
chr6_+_31553955	1.210	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr5_+_150157507	1.195	NM_032947	C5orf62	chromosome 5 open reading frame 62
chr16_-_28608367	1.195	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chrX_+_103031433	1.188	NM_001128834	PLP1	proteolipid protein 1
chr5_+_152870083	1.181	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chrX_+_103031753	1.174	NM_000533 NM_199478	PLP1	proteolipid protein 1
chr22_+_23229959	1.157	NM_001178126	IGLL5 IGLC1	immunoglobulin lambda-like polypeptide 5 immunoglobulin lambda constant 1 (Mcg marker)
chr3_+_46283871	1.156	NM_001164680 NM_001837 NM_178328 NM_178329	CCR3	chemokine (C-C motif) receptor 3
chr2_-_119605758	1.149	NM_001426	EN1	engrailed homeobox 1
chr11_-_78052925	1.128	NM_012296	GAB2	GRB2-associated binding protein 2
chr18_-_53089722	1.117	NM_001243233	TCF4	transcription factor 4
chr12_+_105153258	1.117		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr18_-_53255734	1.112	NM_001083962 NM_001243230 NM_003199	TCF4	transcription factor 4
chr18_-_60795878	1.080		BCL2	B-cell CLL/lymphoma 2
chr2_+_102979096	1.075	NM_003855	IL18R1	interleukin 18 receptor 1
chr12_-_16759430	1.066		LMO3	LIM domain only 3 (rhombotin-like 2)
chr5_+_161494647	1.042	NM_000816 NM_198903 NM_198904	GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr7_-_38313232	1.031	NM_001003799 NM_001003806	TARP TRGV9	TCR gamma alternate reading frame protein T cell receptor gamma variable 9
chr2_+_218990735	1.024	NM_001557	CXCR2	chemokine (C-X-C motif) receptor 2
chr1_-_72748147	1.023	NM_173808	NEGR1	neuronal growth regulator 1
chr5_+_180467224	1.018	NM_152547	BTNL9	butyrophilin-like 9
chr1_-_72748491	0.999
chr6_+_29894105	0.994
chr6_+_31582978	0.988	NM_004847 NM_001623	AIF1	allograft inflammatory factor 1
chr8_-_109095836	0.988	NM_178565	RSPO2	R-spondin 2
chr4_+_81952118	0.986	NM_001201	BMP3	bone morphogenetic protein 3
chr12_+_121570630	0.968	NM_002562	P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7
chr3_-_142166862	0.966		XRN1	5'-3' exoribonuclease 1
chr19_-_4916814	0.950
chr1_+_207070787	0.939	NM_001185156 NM_001185157 NM_001185158 NM_006850	IL24	interleukin 24
chr1_-_182357757	0.916		GLUL	glutamate-ammonia ligase
chr3_+_51895644	0.916	NM_203424	IQCF2	IQ motif containing F2
chr19_+_55105046	0.899	NM_006863	LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr4_+_40198526	0.885	NM_004310	RHOH	ras homolog gene family, member H
chr12_-_8088629	0.875	NM_006931	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3
chr15_+_52201590	0.872		TMOD3	tropomodulin 3 (ubiquitous)
chr11_-_114466471	0.855	NM_001077639 NM_017678	FAM55D	family with sequence similarity 55, member D
chr8_+_39771327	0.828	NM_002164	IDO1	indoleamine 2,3-dioxygenase 1
chr10_-_116286570	0.824		ABLIM1	actin binding LIM protein 1
chr4_-_87770267	0.820	NM_197965	SLC10A6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr5_-_146460991	0.815	NM_181677 NM_181678	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr12_-_16758839	0.798	NM_001243612	LMO3	LIM domain only 3 (rhombotin-like 2)
chr10_+_95326397	0.797	NM_001195755 NM_181745	O3FAR1	omega-3 fatty acid receptor 1
chr19_+_14544216	0.787		PKN1	protein kinase N1
chr12_+_10124007	0.786	NM_138337 NM_201623	CLEC12A CLEC12B	C-type lectin domain family 12, member A C-type lectin domain family 12, member B
chr20_-_47874147	0.768		ZNFX1	zinc finger, NFX1-type containing 1
chr4_-_120987890	0.767	NM_002358	MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)
chr1_-_182357871	0.767		GLUL	glutamate-ammonia ligase
chr7_+_69064580	0.764		AUTS2	autism susceptibility candidate 2
chr14_-_69259654	0.751		ZFP36L1	zinc finger protein 36, C3H type-like 1
chr11_+_63273555	0.751		LGALS12	lectin, galactoside-binding, soluble, 12
chr3_-_21792815	0.745	NM_024697	ZNF385D	zinc finger protein 385D
chr2_-_96987618	0.744
chr5_+_139876504	0.733		ANKHD1	ankyrin repeat and KH domain containing 1
chr11_+_114549199	0.732	NM_182495	FAM55B	family with sequence similarity 55, member B
chr15_+_67418053	0.725	NM_001145102	SMAD3	SMAD family member 3
chr5_-_175395544	0.725	NM_032361	THOC3	THO complex 3
chr1_+_26644380	0.720	NM_001803	CD52	CD52 molecule
chr1_-_182360889	0.718		GLUL	glutamate-ammonia ligase
chr3_+_111260925	0.712	NM_005816 NM_198196	CD96	CD96 molecule
chr16_+_31366468	0.712	NM_000887	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr12_-_120687956	0.708	NM_025157	PXN	paxillin
chr16_-_84273303	0.705	NM_172347	KCNG4	potassium voltage-gated channel, subfamily G, member 4
chr5_-_58882274	0.696	NM_006203	PDE4D	phosphodiesterase 4D, cAMP-specific
chr1_-_151032082	0.694	NM_001038707 NM_020239	CDC42SE1	CDC42 small effector 1
chr7_-_23509972	0.686	NM_006547	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr3_-_9921933	0.682	NM_001199551 NM_001199552	CIDEC	cell death-inducing DFFA-like effector c
chr4_-_82126200	0.677	NM_006259	PRKG2	protein kinase, cGMP-dependent, type II
chr2_-_214015053	0.674	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chrX_+_155227245	0.666	NM_002186	IL9R	interleukin 9 receptor
chr19_+_10959105	0.664	NM_001136482	C19orf38	chromosome 19 open reading frame 38
chr18_-_60986508	0.663	NM_000633 NM_000657	BCL2	B-cell CLL/lymphoma 2
chrY_+_59330251	0.661	NM_002186	IL9R	interleukin 9 receptor
chr12_-_8693391	0.661	NM_014358	CLEC4E	C-type lectin domain family 4, member E
chr22_-_39640956	0.660	NM_002608	PDGFB	platelet-derived growth factor beta polypeptide
chr1_-_20445991	0.659	NM_012400	PLA2G2D	phospholipase A2, group IID
chr1_-_182360181	0.654		GLUL	glutamate-ammonia ligase
chr3_+_122296432	0.654	NM_001113523	PARP15	poly (ADP-ribose) polymerase family, member 15
chr6_+_32407618	0.653	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr6_+_29855349	0.649		HLA-H	major histocompatibility complex, class I, H (pseudogene)
chr12_+_104850986	0.648		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr12_+_116997185	0.645	NM_001085481	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2
chr4_-_176733413	0.642		GPM6A	glycoprotein M6A
chr3_+_119298522	0.640	NM_001125	ADPRH	ADP-ribosylarginine hydrolase
chr11_-_114466397	0.640		FAM55D	family with sequence similarity 55, member D
chr16_+_50731049	0.637	NM_022162	NOD2	nucleotide-binding oligomerization domain containing 2
chr5_-_175394949	0.637		THOC3	THO complex 3
chr6_-_32557431	0.632	NM_001243965 NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr16_+_71879858	0.632
chr12_-_95044205	0.625	NM_020698	TMCC3	transmembrane and coiled-coil domain family 3
chr3_-_71632741	0.618	NM_001244808 NM_001012505 NM_001244810 NM_032682	FOXP1	forkhead box P1
chr21_+_19289656	0.610	NM_001204175 NM_001204176 NM_001204177 NM_001204178	CHODL	chondrolectin
chr4_-_176733378	0.605		GPM6A	glycoprotein M6A
chr7_+_134233848	0.604	NM_001080538	AKR1B15	aldo-keto reductase family 1, member B15
chr17_-_1412995	0.599		INPP5K	inositol polyphosphate-5-phosphatase K
chr22_-_17700265	0.598		CECR1	cat eye syndrome chromosome region, candidate 1
chr16_-_28621279	0.597	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_-_45996470	0.592	NM_206901	RTN2	reticulon 2
chrX_-_101410761	0.588	NM_001159560 NM_001012978	BEX5	brain expressed, X-linked 5
chr17_+_72322350	0.585	NM_153209	KIF19	kinesin family member 19
chr3_+_194406614	0.577	NM_153690	FAM43A	family with sequence similarity 43, member A
chr11_-_94964209	0.576	NM_144665	SESN3	sestrin 3
chr7_-_83278478	0.570	NM_012431	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_74109417	0.569	NM_173582	PGM2L1	phosphoglucomutase 2-like 1
chr19_-_16250695	0.568
chr7_-_96654128	0.567	NM_005221	DLX5	distal-less homeobox 5
chr5_+_108083522	0.551	NM_005246	FER	fer (fps/fes related) tyrosine kinase
chr12_-_16759420	0.547		LMO3	LIM domain only 3 (rhombotin-like 2)
chr5_-_95748688	0.540	NM_001177876	PCSK1	proprotein convertase subtilisin/kexin type 1
chr6_-_137494719	0.534	NM_052962 NM_181309 NM_181310	IL22RA2	interleukin 22 receptor, alpha 2
chr22_-_32651317	0.526	NM_014227	SLC5A4	solute carrier family 5 (low affinity glucose cotransporter), member 4
chr6_-_31560497	0.524	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr5_-_142783059	0.523		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_+_72848108	0.522	NM_003508	FZD9	frizzled family receptor 9
chr11_-_124622034	0.521		VSIG2	V-set and immunoglobulin domain containing 2
chr6_-_149806025	0.517		ZC3H12D	zinc finger CCCH-type containing 12D
chr20_-_52210780	0.514		ZNF217	zinc finger protein 217
chr11_+_60102294	0.503	NM_139249	MS4A6E	membrane-spanning 4-domains, subfamily A, member 6E
chr12_-_57644905	0.502	NM_145064	STAC3	SH3 and cysteine rich domain 3
chr5_+_147258273	0.496	NM_054023	SCGB3A2	secretoglobin, family 3A, member 2
chr19_+_14544100	0.491	NM_002741	PKN1	protein kinase N1
chr4_-_176733901	0.488		GPM6A	glycoprotein M6A
chr7_+_18330044	0.488		HDAC9	histone deacetylase 9
chr18_-_60987212	0.486		BCL2	B-cell CLL/lymphoma 2
chr18_-_53255361	0.486		TCF4	transcription factor 4
chr6_-_32805819	0.485		TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr12_-_95945226	0.485	NM_032147	USP44	ubiquitin specific peptidase 44
chr13_-_41593491	0.483	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr6_-_32806009	0.483		TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_72363545	0.480	NM_181790	GPR142	G protein-coupled receptor 142
chr5_-_142783288	0.480		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_-_136875629	0.474	NM_003467	CXCR4	chemokine (C-X-C motif) receptor 4
chr17_-_41738901	0.474	NM_004527 NM_013999	MEOX1	mesenchyme homeobox 1
chr7_+_26191732	0.473	NM_004289	NFE2L3	nuclear factor (erythroid-derived 2)-like 3
chr9_-_27573444	0.471	NM_018325	C9orf72	chromosome 9 open reading frame 72
chr13_-_114898013	0.470		RASA3	RAS p21 protein activator 3
chr4_-_140060601	0.469	NM_201999	ELF2	E74-like factor 2 (ets domain transcription factor)
chrX_+_2609224	0.468	NM_001122898 NM_002414	CD99	CD99 molecule
chr11_-_124622085	0.453	NM_014312	VSIG2	V-set and immunoglobulin domain containing 2
chr12_-_10562142	0.451	NM_013431	KLRC4-KLRK1 KLRC4	KLRC4-KLRK1 readthrough killer cell lectin-like receptor subfamily C, member 4
chr1_+_26644458	0.450		CD52	CD52 molecule
chr17_+_43299277	0.450	NM_005892	FMNL1	formin-like 1
chr13_-_114898057	0.450		RASA3	RAS p21 protein activator 3
chr3_+_69134057	0.448	NM_006407	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chrX_-_19688991	0.436	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr9_-_91793375	0.431		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr9_-_123676849	0.430	NM_001190947	TRAF1	TNF receptor-associated factor 1
chr2_+_157291979	0.429		GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr1_+_168545710	0.426	NM_002995	XCL1	chemokine (C motif) ligand 1
chr1_-_26699225	0.426	NM_001114759 NM_173574	ZNF683	zinc finger protein 683
chr12_+_10460416	0.421	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr4_-_109089444	0.419	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr9_-_135282164	0.417	NM_001205296 NM_007344	TTF1	transcription termination factor, RNA polymerase I
chr6_+_29910246	0.416	NM_001242758 NM_002116	HLA-A	major histocompatibility complex, class I, A
chr22_+_37447615	0.416	NM_024681	KCTD17	potassium channel tetramerisation domain containing 17
chrY_+_2559224	0.414	NM_001122898 NM_002414	CD99	CD99 molecule
chr2_-_87018802	0.414	NM_001768 NM_171827	CD8A	CD8a molecule
chr14_-_92333856	0.406	NM_001128596	TC2N	tandem C2 domains, nuclear
chr2_+_122407564	0.405		LOC254128	uncharacterized LOC254128
chr22_+_36960325	0.403
chr10_+_114135013	0.402	NM_203380	ACSL5	acyl-CoA synthetase long-chain family member 5
chr1_+_25598883	0.402	NM_001127691 NM_016124	RHD	Rh blood group, D antigen

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
6.12	9.05e-05	GO:0006952	defense response
27.82	3.80e-03	GO:0006968	cellular defense response
4.06	6.45e-03	GO:0002376	immune system process
8.18	2.52e-02	GO:0019932	second-messenger-mediated signaling

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.26	1.25e-05	GO:0031224	intrinsic to membrane
2.22	3.79e-05	GO:0016021	integral to membrane
1.94	4.53e-04	GO:0044425	membrane part
1.71	2.67e-03	GO:0016020	membrane
62.57	2.71e-02	GO:0043209	myelin sheath

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
20.87	2.08e-05	GO:0019955	cytokine binding
3.83	6.58e-05	GO:0004872	receptor activity
3.33	1.91e-04	GO:0004871	signal transducer activity
3.33	1.91e-04	GO:0060089	molecular transducer activity
56.31	1.08e-03	GO:0001637	G-protein chemoattractant receptor activity
56.31	1.08e-03	GO:0004950	chemokine receptor activity
51.19	1.45e-03	GO:0019956	chemokine binding
3.82	2.15e-03	GO:0004888	transmembrane receptor activity
125.11	5.81e-03	GO:0016494	C-X-C chemokine receptor activity
107.24	8.13e-03	GO:0019958	C-X-C chemokine binding