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• Activity deltas table
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Motif ID: PAX6.p2

Z-value: 0.996

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_77610610	4.628		SHROOM3	shroom family member 3
chr4_-_174320616	4.597	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr11_+_117947785	4.151		TMPRSS4	transmembrane protease, serine 4
chr11_+_117947726	3.620	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr13_+_53602829	3.198	NM_006418	OLFM4	olfactomedin 4
chr12_-_71031174	3.133	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr3_-_119379269	2.512	NM_022135	POPDC2	popeye domain containing 2
chr9_-_116861336	2.468	NM_138424	KIF12	kinesin family member 12
chr17_-_39041436	2.391	NM_019010	KRT20	keratin 20
chr5_+_40909558	2.366	NM_000587	C7	complement component 7
chr16_+_72097124	1.925	NM_020995	HPR	haptoglobin-related protein
chr5_-_142077508	1.917	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr7_+_80267972	1.872		CD36	CD36 molecule (thrombospondin receptor)
chrX_-_13835213	1.779		GPM6B	glycoprotein M6B
chr1_+_150480584	1.740		ECM1	extracellular matrix protein 1
chr3_-_58652469	1.726	NM_138805	FAM3D	family with sequence similarity 3, member D
chr11_+_111789658	1.664		C11orf52	chromosome 11 open reading frame 52
chr13_-_110802708	1.662		COL4A1	collagen, type IV, alpha 1
chr1_+_94057518	1.662		LOC100129046	uncharacterized LOC100129046
chr3_-_195310770	1.550		APOD	apolipoprotein D
chr1_+_94057581	1.516		LOC100129046	uncharacterized LOC100129046
chr5_+_40909487	1.495		C7	complement component 7
chr4_+_77356252	1.464	NM_020859	SHROOM3	shroom family member 3
chr16_+_72088507	1.429	NM_001126102 NM_005143	HP	haptoglobin
chr4_-_65275000	1.394	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chrX_-_130423199	1.389		IGSF1	immunoglobulin superfamily, member 1
chr5_-_141338626	1.379	NM_016580	PCDH12	protocadherin 12
chr2_+_170366211	1.375	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr9_-_95166827	1.268	NM_014057 NM_033014	OGN	osteoglycin
chr11_+_111789600	1.262	NM_080659	C11orf52	chromosome 11 open reading frame 52
chrX_-_130423387	1.207	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr5_+_42756919	1.120	NM_001134848	CCDC152	coiled-coil domain containing 152
chr12_+_109551041	0.919
chr4_+_113970784	0.903	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr2_-_163008913	0.839	NM_002054	GCG	glucagon
chr11_+_14926542	0.788		CALCB	calcitonin-related polypeptide beta
chr3_+_111717585	0.774	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr9_-_116861506	0.760		KIF12	kinesin family member 12
chr17_+_58499854	0.750	NM_181707	C17orf64	chromosome 17 open reading frame 64
chr12_+_18414473	0.750	NM_004570	PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide
chr1_+_114522029	0.738	NM_020190	OLFML3	olfactomedin-like 3
chr21_-_31588242	0.732	NM_199328	CLDN8	claudin 8
chrX_-_13835187	0.720		GPM6B	glycoprotein M6B
chr16_+_82068958	0.716		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr17_+_8213555	0.697	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr17_+_9745847	0.686		GLP2R	glucagon-like peptide 2 receptor
chr16_+_82068910	0.655		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr10_-_82049178	0.648	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr1_+_150480486	0.648	NM_001202858 NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chrX_-_65259839	0.646	NM_001100431 NM_001184830 NM_001184831 NM_007268	VSIG4	V-set and immunoglobulin domain containing 4
chr10_-_7659186	0.638		ITIH5	inter-alpha-trypsin inhibitor heavy chain family, member 5
chr4_-_10686314	0.631	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chrX_+_148769902	0.602	NM_001011544	MAGEA11	melanoma antigen family A, 11
chr7_+_22766765	0.590	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr16_+_82068830	0.583	NM_002153	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr7_+_80267922	0.569		CD36	CD36 molecule (thrombospondin receptor)
chr20_+_32250089	0.562	NM_080825	C20orf144	chromosome 20 open reading frame 144
chr15_+_65337707	0.561	NM_178859	OSTBETA	organic solute transporter beta
chr7_+_80267782	0.561	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr3_+_108015392	0.560		HHLA2	HERV-H LTR-associating 2
chr20_-_44144263	0.559	NM_006652	SPINT3	serine peptidase inhibitor, Kunitz type, 3
chr5_+_79615789	0.558	NM_032567	SPZ1	spermatogenic leucine zipper 1
chrX_-_13835313	0.544	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr1_+_209878135	0.543	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr3_-_149051258	0.541	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr4_+_88896801	0.523	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr9_+_103340335	0.511	NM_001018116	MURC	muscle-related coiled-coil protein
chr20_+_9288446	0.508	NM_000933	PLCB4	phospholipase C, beta 4
chr17_+_8214139	0.505	NM_025014	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr4_+_100495972	0.496		MTTP	microsomal triglyceride transfer protein
chrX_-_15332680	0.496	NM_001012428	ASB11	ankyrin repeat and SOCS box containing 11
chr18_+_61420276	0.494	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_147374945	0.477	NM_005267	GJA8	gap junction protein, alpha 8, 50kDa
chrX_-_13835012	0.452		GPM6B	glycoprotein M6B
chr8_-_62602285	0.448	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr20_-_1309809	0.444	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr17_-_9694613	0.437	NM_001105571 NM_001220493	DHRS7C	dehydrogenase/reductase (SDR family) member 7C
chr11_+_19372270	0.427	NM_001111018	NAV2	neuron navigator 2
chr16_-_48266181	0.424	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr4_-_184241926	0.420	NM_001111319	CLDN22	claudin 22
chr9_+_124048396	0.414		GSN	gelsolin
chr9_-_95244750	0.409	NM_001193335 NM_017680	ASPN	asporin
chr6_-_10412606	0.402	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_25470067	0.396		RARB	retinoic acid receptor, beta
chr2_-_133539627	0.396		NCKAP5	NCK-associated protein 5
chr1_+_108992903	0.392	NM_001143987 NM_001143988	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chrX_+_2670092	0.374	NM_001141919 NM_001141920 NM_175569	XGPY2 XG	Xg pseudogene, Y-linked 2 Xg blood group
chr21_-_39870303	0.371	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr6_-_76203256	0.356	NM_015687	FILIP1	filamin A interacting protein 1
chr3_+_119500930	0.356		NR1I2	nuclear receptor subfamily 1, group I, member 2
chrX_-_106449543	0.342	NM_017681	NUP62CL	nucleoporin 62kDa C-terminal like
chr12_+_56915587	0.338	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr6_-_131291480	0.331	NM_001199389	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr9_-_16870664	0.330		BNC2	basonuclin 2
chr1_-_182922504	0.324	NM_030933	SHCBP1L	SHC SH2-domain binding protein 1-like
chr3_-_128186090	0.319	NM_153330	DNAJB8	DnaJ (Hsp40) homolog, subfamily B, member 8
chr5_+_85913755	0.318		COX7C	cytochrome c oxidase subunit VIIc
chr15_+_45544427	0.313	NM_004212	SLC28A2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr1_-_211666258	0.311	NM_001164688 NM_183059	RD3	retinal degeneration 3
chr8_-_7673137	0.310	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr8_+_7705401	0.301	NM_058203 NM_001081552	SPAG11B SPAG11A	sperm associated antigen 11B sperm associated antigen 11A
chr11_-_117747331	0.290		FXYD6	FXYD domain containing ion transport regulator 6
chr6_-_49989647	0.282	NM_001037497 NM_001037728	DEFB110	defensin, beta 110 locus
chr1_-_31345361	0.281		SDC3	syndecan 3
chr4_+_187148624	0.278	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr2_+_115822246	0.276	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr4_-_26491888	0.276	NM_000730	CCKAR	cholecystokinin A receptor
chr9_-_85946875	0.273	NM_001244961	FRMD3	FERM domain containing 3
chr1_-_108786663	0.270	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr10_+_124030820	0.267	NM_144587	BTBD16	BTB (POZ) domain containing 16
chr6_-_48078909	0.266		C6orf138	chromosome 6 open reading frame 138
chr4_+_15429628	0.263	NM_031911	C1QTNF7	C1q and tumor necrosis factor related protein 7
chr21_-_31933607	0.256	NM_181614	KRTAP19-7	keratin associated protein 19-7
chr18_+_18822168	0.246	NM_001142966	GREB1L	growth regulation by estrogen in breast cancer-like
chr5_+_140254930	0.246	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr3_+_133495925	0.234		TF	transferrin
chr3_+_121286777	0.230	NM_001012659	ARGFX	arginine-fifty homeobox
chr17_-_34503914	0.227	NM_001001417	TBC1D3B TBC1D3C TBC1D3G	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G
chr7_+_80275634	0.202	NM_001127443 NM_001127444	CD36	CD36 molecule (thrombospondin receptor)
chr20_+_4702499	0.200	NM_012409	PRND	prion protein 2 (dublet)
chr6_+_101846668	0.199		GRIK2	glutamate receptor, ionotropic, kainate 2
chr5_+_140174443	0.195	NM_018905 NM_031495	PCDHA2	protocadherin alpha 2
chr4_+_71263598	0.193	NM_021225	PROL1	proline rich, lacrimal 1
chrX_-_15333726	0.191	NM_001201583 NM_080873	ASB11	ankyrin repeat and SOCS box containing 11
chr5_+_175223519	0.188	NM_006650	CPLX2	complexin 2
chr3_-_146323025	0.184		PLSCR5	phospholipid scramblase family, member 5
chr5_-_35048239	0.183	NM_031900	AGXT2	alanine--glyoxylate aminotransferase 2
chr17_+_36283959	0.163	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chr5_+_140734767	0.160	NM_018917 NM_032053	PCDHGA4	protocadherin gamma subfamily A, 4
chr9_-_14779530	0.156	NM_001177704	FREM1	FRAS1 related extracellular matrix 1
chr12_-_2986299	0.156	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr8_+_39792473	0.155	NM_194294	IDO2	indoleamine 2,3-dioxygenase 2
chr6_-_131321868	0.153	NM_001252660	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chrY_-_27198250	0.145	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chrY_+_25130409	0.143	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chr1_+_61924621	0.132		NFIA	nuclear factor I/A
chrY_+_26764150	0.130	NM_001002760 NM_001002761 NM_004678	BPY2B BPY2C BPY2	basic charge, Y-linked, 2B basic charge, Y-linked, 2C basic charge, Y-linked, 2
chr6_+_167704802	0.127	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr1_+_186798031	0.124	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr8_-_11853759	0.123	NM_001033019	DEFB134	defensin, beta 134
chr3_+_119501556	0.119	NM_022002	NR1I2	nuclear receptor subfamily 1, group I, member 2
chr17_-_8661876	0.117	NM_001128076	SPDYE4	speedy homolog E4 (Xenopus laevis)
chr19_-_14910947	0.116	NM_198944	OR7C1	olfactory receptor, family 7, subfamily C, member 1
chr7_+_73275488	0.113	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr18_-_45663667	0.110	NM_001039360	ZBTB7C	zinc finger and BTB domain containing 7C
chr11_+_71903172	0.106	NM_016729	FOLR1	folate receptor 1 (adult)
chr8_-_93111915	0.093	NM_001198628	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_136788012	0.092	NM_001198615	MAP7	microtubule-associated protein 7
chr1_+_47533046	0.088	NM_178134	CYP4Z1	cytochrome P450, family 4, subfamily Z, polypeptide 1
chr11_+_844445	0.083	NM_001025237	TSPAN4	tetraspanin 4
chr2_+_62934030	0.074	NM_001142614	EHBP1	EH domain binding protein 1
chr11_-_57298180	0.073	NM_012456	TIMM10	translocase of inner mitochondrial membrane 10 homolog (yeast)
chr5_-_58334936	0.071	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr8_+_124194873	0.070		FAM83A	family with sequence similarity 83, member A
chr19_+_9203854	0.067	NM_001004456	OR1M1	olfactory receptor, family 1, subfamily M, member 1
chr18_+_32073343	0.065		DTNA	dystrobrevin, alpha
chr16_-_51184507	0.062	NM_001127892	SALL1	sal-like 1 (Drosophila)
chr3_+_49506079	0.062	NM_001177643	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr1_+_184356186	0.060		C1orf21	chromosome 1 open reading frame 21
chr1_+_159409511	0.058	NM_012351	OR10J1	olfactory receptor, family 10, subfamily J, member 1
chr16_-_27899477	0.054	NM_144675	GSG1L	GSG1-like
chr4_+_71226477	0.042	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr12_-_16430618	0.041	NM_001170798	SLC15A5	solute carrier family 15, member 5
chr17_-_34591958	0.040	NM_001001418	TBC1D3C TBC1D3G	TBC1 domain family, member 3C TBC1 domain family, member 3G
chr17_-_36348585	0.038	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chr1_-_13611532	0.038	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chr9_-_140142165	0.032	NM_001001710	FAM166A	family with sequence similarity 166, member A
chr1_+_160147200	0.030	NM_001001734	ATP1A4	ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr17_-_34756980	0.029	NM_001123392	TBC1D3C TBC1D3G TBC1D3 TBC1D3H	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H
chr10_+_102222797	0.027	NM_003393	WNT8B	wingless-type MMTV integration site family, member 8B
chr10_-_79628870	0.027		DLG5	discs, large homolog 5 (Drosophila)
chr12_-_7848324	0.026	NM_020634	GDF3	growth differentiation factor 3
chr6_-_28483563	0.025	NM_182701	GPX6	glutathione peroxidase 6 (olfactory)
chr5_+_147715121	0.023	NM_001040433	SPINK9	serine peptidase inhibitor, Kazal type 9
chrX_-_84363973	0.015	NM_001012980	SATL1	spermidine/spermine N1-acetyl transferase-like 1
chr14_+_29241989	0.008		C14orf23	chromosome 14 open reading frame 23
chr6_-_75994631	0.007	NM_001143958 NM_018247	TMEM30A	transmembrane protein 30A
chr15_-_85197502	0.004		WDR73	WD repeat domain 73
chr14_+_102276125	0.004	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
4.47	8.10e-05	GO:0005576	extracellular region
5.86	1.19e-03	GO:0044421	extracellular region part
5.71	1.75e-02	GO:0005615	extracellular space
9.24	3.22e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
234.58	5.92e-04	GO:0030492	hemoglobin binding