Motif ID: PDX1.p2

Z-value: 1.055


Transcription factors associated with PDX1.p2:

Gene SymbolEntrez IDGene Name
PDX1 3651 pancreatic and duodenal homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PDX1hg19_v1_chr13_+_28494136_28494272-0.476.4e-03Click!


Activity profile for motif PDX1.p2.

activity profile for motif PDX1.p2


Sorted Z-values histogram for motif PDX1.p2

Sorted Z-values for motif PDX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_63063186 7.959 NM_014495
 ANGPTL3
angiopoietin-like 3
chr6_-_133035180 7.434 NM_004666
 VNN1
vanin 1
chr2_-_158300517 6.032 NM_004288
 CYTIP
cytohesin 1 interacting protein
chr19_-_7766978 3.670 NM_001220500
NM_002002
 FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

chr15_-_40398286 3.000 NM_001003942
NM_001003943
 BMF

Bcl2 modifying factor

chr12_+_10460416 2.575 NM_002262
NM_007334
 KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr1_+_40862471 2.560 NM_001198980
 SMAP2
small ArfGAP2
chr15_-_44969085 2.551 NM_001145112
 PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr15_+_48498497 2.228 NM_000338
NM_001184832
 SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr4_-_48136245 2.087 NM_003328
 TXK
TXK tyrosine kinase
chr4_+_74606222 2.019 NM_000584
 IL8
interleukin 8
chr11_+_22696381 1.919 GAS2
growth arrest-specific 2
chr19_-_50847957 1.829 NAPSB
napsin B aspartic peptidase pseudogene
chr21_-_46348633 1.771 NM_001127491
 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_161601251 1.742 NM_001244753
 FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr6_-_41254392 1.714 NM_001242589
NM_001242590
NM_018643
 TREM1


triggering receptor expressed on myeloid cells 1


chr4_+_74281884 1.698 ALB
albumin
chr16_+_29674979 1.629 SPN
sialophorin
chr3_-_120400957 1.613 HGD
homogentisate 1,2-dioxygenase
chr19_-_14785626 1.589 NM_032571
 EMR3
egf-like module containing, mucin-like, hormone receptor-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
7.09 1.25e-02 GO:0002684 positive regulation of immune system process
7.02 1.33e-02 GO:0050776 regulation of immune response
5.90 3.83e-03 GO:0002682 regulation of immune system process
4.58 2.81e-02 GO:0009611 response to wounding
4.09 1.14e-02 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
4.45 2.22e-02 GO:0005615 extracellular space
2.83 2.23e-02 GO:0005576 extracellular region
2.34 1.02e-03 GO:0071944 cell periphery
2.27 3.20e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
51.51 3.00e-02 GO:0019865 immunoglobulin binding
28.11 7.16e-03 GO:0043498 cell surface binding