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Motif ID: PDX1.p2

Z-value: 1.055

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_63063186	7.959	NM_014495	ANGPTL3	angiopoietin-like 3
chr6_-_133035180	7.434	NM_004666	VNN1	vanin 1
chr2_-_158300517	6.032	NM_004288	CYTIP	cytohesin 1 interacting protein
chr19_-_7766978	3.670	NM_001220500 NM_002002	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr15_-_40398286	3.000	NM_001003942 NM_001003943	BMF	Bcl2 modifying factor
chr12_+_10460416	2.575	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr1_+_40862471	2.560	NM_001198980	SMAP2	small ArfGAP2
chr15_-_44969085	2.551	NM_001145112	PATL2	protein associated with topoisomerase II homolog 2 (yeast)
chr15_+_48498497	2.228	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr4_-_48136245	2.087	NM_003328	TXK	TXK tyrosine kinase
chr4_+_74606222	2.019	NM_000584	IL8	interleukin 8
chr11_+_22696381	1.919		GAS2	growth arrest-specific 2
chr19_-_50847957	1.829		NAPSB	napsin B aspartic peptidase pseudogene
chr21_-_46348633	1.771	NM_001127491	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_161601251	1.742	NM_001244753	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr6_-_41254392	1.714	NM_001242589 NM_001242590 NM_018643	TREM1	triggering receptor expressed on myeloid cells 1
chr4_+_74281884	1.698		ALB	albumin
chr16_+_29674979	1.629		SPN	sialophorin
chr3_-_120400957	1.613		HGD	homogentisate 1,2-dioxygenase
chr19_-_14785626	1.589	NM_032571	EMR3	egf-like module containing, mucin-like, hormone receptor-like 3
chr6_+_130339715	1.552	NM_001007102 NM_032438	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr3_+_52813936	1.547	NM_001166435 NM_001166436	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr17_-_7082654	1.518	NM_001197216 NM_001671	ASGR1	asialoglycoprotein receptor 1
chr3_+_108541544	1.504	NM_016388	TRAT1	T cell receptor associated transmembrane adaptor 1
chr9_+_136501484	1.474	NM_000787	DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr11_+_5410606	1.466	NM_001004756	OR51M1	olfactory receptor, family 51, subfamily M, member 1
chr1_-_157670280	1.463	NM_052939	FCRL3	Fc receptor-like 3
chr2_+_185463235	1.452		ZNF804A	zinc finger protein 804A
chr12_+_47610051	1.445	NM_138371	FAM113B	family with sequence similarity 113, member B
chr6_+_33043702	1.445	NM_002121	HLA-DPB1	major histocompatibility complex, class II, DP beta 1
chr17_+_7482961	1.438		CD68	CD68 molecule
chr15_-_40398573	1.390	NM_033503	BMF	Bcl2 modifying factor
chr17_+_7482938	1.381		CD68	CD68 molecule
chr6_-_55740387	1.331		BMP5	bone morphogenetic protein 5
chrX_+_123480131	1.308	NM_001114937 NM_002351	SH2D1A	SH2 domain containing 1A
chr4_+_187187342	1.280		F11	coagulation factor XI
chr17_+_7482980	1.229		CD68	CD68 molecule
chr4_+_108814419	1.122	NM_001136257 NM_152621	SGMS2	sphingomyelin synthase 2
chr8_+_32579350	1.118	NM_001159996	NRG1	neuregulin 1
chr12_-_57873364	1.108	NM_001080157	ARHGAP9	Rho GTPase activating protein 9
chrX_+_123234462	1.100		STAG2	stromal antigen 2
chr2_+_185463292	1.099		ZNF804A	zinc finger protein 804A
chr7_+_80267972	1.071		CD36	CD36 molecule (thrombospondin receptor)
chrY_+_16733900	1.070	NM_001164238	NLGN4Y	neuroligin 4, Y-linked
chr12_-_9885859	1.059	NM_001253748 NM_001253750 NM_172004	CLECL1	C-type lectin-like 1
chr12_+_47610244	1.058		FAM113B	family with sequence similarity 113, member B
chr4_+_78432905	1.026	NM_006419	CXCL13	chemokine (C-X-C motif) ligand 13
chrX_-_131547536	1.010	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chrX_+_49091926	0.993	NM_014008	CCDC22	coiled-coil domain containing 22
chr7_-_92777657	0.992	NM_152703	SAMD9L	sterile alpha motif domain containing 9-like
chr16_-_67517715	0.964	NM_001138	AGRP	agouti related protein homolog (mouse)
chr7_+_120965420	0.948	NM_016087	WNT16	wingless-type MMTV integration site family, member 16
chr18_-_51690988	0.926		MBD2	methyl-CpG binding domain protein 2
chr1_+_158979681	0.919	NM_001206567 NM_005531	IFI16	interferon, gamma-inducible protein 16
chr15_+_80364902	0.917	NM_001242915 NM_001242916	ZFAND6	zinc finger, AN1-type domain 6
chrX_+_49091931	0.902		CCDC22	coiled-coil domain containing 22
chr16_+_70557724	0.893		SF3B3	splicing factor 3b, subunit 3, 130kDa
chr1_-_161519817	0.874	NM_000569 NM_001127592	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr4_+_86396251	0.855	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr2_-_166060552	0.847	NM_001081676 NM_001081677 NM_006922	SCN3A	sodium channel, voltage-gated, type III, alpha subunit
chr16_+_29674282	0.833	NM_001030288	SPN	sialophorin
chr2_+_113735595	0.828	NM_019618	IL36G	interleukin 36, gamma
chr16_+_70557726	0.820		SF3B3	splicing factor 3b, subunit 3, 130kDa
chr17_+_7482804	0.795	NM_001251 NM_001040059	CD68	CD68 molecule
chr8_-_20040612	0.789	NM_001135691 NM_001142324 NM_001142325 NM_003053	SLC18A1	solute carrier family 18 (vesicular monoamine), member 1
chr1_-_33841142	0.789	NM_198040	PHC2	polyhomeotic homolog 2 (Drosophila)
chr5_+_54398473	0.784	NM_006144	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr17_-_39637351	0.758	NM_002280	KRT35	keratin 35
chr12_-_4488707	0.740	NM_020638	FGF23	fibroblast growth factor 23
chr1_+_186265404	0.730	NM_001127708 NM_001127709 NM_001127710 NM_005807	PRG4	proteoglycan 4
chr4_-_72649734	0.714	NM_000583	GC	group-specific component (vitamin D binding protein)
chr16_+_70557688	0.705	NM_012426	SF3B3	splicing factor 3b, subunit 3, 130kDa
chr10_+_35484829	0.705	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chr6_-_39072412	0.673		C6orf64	chromosome 6 open reading frame 64
chr1_+_101003692	0.654	NM_022049	GPR88	G protein-coupled receptor 88
chr16_+_28505920	0.650	NM_018690	APOBR	apolipoprotein B receptor
chr17_-_42144001	0.648		LSM12	LSM12 homolog (S. cerevisiae)
chr1_+_57320442	0.642	NM_000562	C8A	complement component 8, alpha polypeptide
chr4_+_71457974	0.619	NM_016519	AMBN	ameloblastin (enamel matrix protein)
chr6_-_134498973	0.617	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr2_+_169757749	0.612	NM_001081686 NM_021176	G6PC2	glucose-6-phosphatase, catalytic, 2
chr21_+_46020496	0.606	NM_198689	KRTAP10-7	keratin associated protein 10-7
chr12_-_53012332	0.598	NM_175068	KRT73	keratin 73
chrX_+_37639306	0.587		CYBB	cytochrome b-245, beta polypeptide
chr16_+_8814567	0.581	NM_001127448	ABAT	4-aminobutyrate aminotransferase
chr17_-_29641094	0.578	NM_006495	EVI2B	ecotropic viral integration site 2B
chr10_+_70980058	0.571	NM_025130	HKDC1	hexokinase domain containing 1
chr8_+_76452202	0.571	NM_004133	HNF4G	hepatocyte nuclear factor 4, gamma
chr3_+_52811601	0.559	NM_002215	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr9_+_82187469	0.554		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_+_17997785	0.551	NM_001105569	MSGN1	mesogenin 1
chr6_-_32731266	0.540	NM_001198858	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr15_+_67841341	0.527	NM_001206804	MAP2K5	mitogen-activated protein kinase kinase 5
chr11_-_116663106	0.526	NM_001166598 NM_052968	APOA5	apolipoprotein A-V
chr7_+_129269916	0.516	NM_001040110	NRF1	nuclear respiratory factor 1
chr11_-_104905849	0.515		CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr13_-_41593491	0.497	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr19_+_37180301	0.496	NM_152603	ZNF567	zinc finger protein 567
chr2_+_24807345	0.487	NM_003743 NM_147223 NM_147233	NCOA1	nuclear receptor coactivator 1
chr3_-_143567163	0.483	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr6_-_55740358	0.472	NM_021073	BMP5	bone morphogenetic protein 5
chr8_-_80993009	0.472	NM_001025252	TPD52	tumor protein D52
chr17_-_39156106	0.466	NM_031959	KRTAP3-2	keratin associated protein 3-2
chr2_+_204055404	0.452		RPL12	ribosomal protein L12
chr4_+_88720701	0.441	NM_004967	IBSP	integrin-binding sialoprotein
chr12_+_15475190	0.436	NM_002848 NM_030667	PTPRO	protein tyrosine phosphatase, receptor type, O
chr9_+_82187599	0.433		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_+_148287656	0.431	NM_145304	C7orf33	chromosome 7 open reading frame 33
chr12_+_105153258	0.431		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr17_-_42144986	0.418	NM_152344	LSM12	LSM12 homolog (S. cerevisiae)
chr17_-_29641068	0.412		EVI2B	ecotropic viral integration site 2B
chr12_-_91398757	0.411	NM_004950	EPYC	epiphycan
chr17_-_29641087	0.405		EVI2B	ecotropic viral integration site 2B
chr5_+_68667280	0.404	NM_133339	RAD17	RAD17 homolog (S. pombe)
chr6_+_167536240	0.403	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr7_-_87342569	0.393	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr2_+_38893051	0.391	NM_138801	GALM	galactose mutarotase (aldose 1-epimerase)
chr2_+_38893238	0.387		GALM	galactose mutarotase (aldose 1-epimerase)
chr2_+_169921298	0.387	NM_005771	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr9_+_141106636	0.378	NM_001145249	FAM157B	family with sequence similarity 157, member B
chr7_+_26400503	0.362	NM_001199837	SNX10	sorting nexin 10
chr4_-_39523132	0.359		UGDH	UDP-glucose 6-dehydrogenase
chr3_-_108672547	0.358	NM_005459	GUCA1C	guanylate cyclase activator 1C
chr6_+_25754926	0.357	NM_005495	SLC17A4	solute carrier family 17 (sodium phosphate), member 4
chr12_-_91398744	0.349		EPYC	epiphycan
chr9_+_33624214	0.336		ANXA2P2	annexin A2 pseudogene 2
chr12_-_103311380	0.335	NM_000277	PAH	phenylalanine hydroxylase
chr1_-_16763887	0.334	NM_198546	SPATA21	spermatogenesis associated 21
chr20_+_43990576	0.332	NM_001197129	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr7_+_104681378	0.329		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr4_+_169013687	0.322	NM_007193	ANXA10	annexin A10
chr6_+_144612872	0.312	NM_007124	UTRN	utrophin
chr6_-_143266283	0.307	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr9_+_97521930	0.297	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr4_-_10023094	0.293	NM_020041	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9
chr17_+_47923271	0.285	NM_001242791	FLJ45513	uncharacterized LOC729220
chr11_+_22696318	0.275	NM_005256	GAS2	growth arrest-specific 2
chr17_+_38119225	0.273	NM_178171	GSDMA	gasdermin A
chrX_+_118708540	0.272		UBE2A	ubiquitin-conjugating enzyme E2A
chr16_-_28620648	0.271	NM_177530 NM_177534	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_+_88911039	0.270	NM_000372	TYR	tyrosinase (oculocutaneous albinism IA)
chr17_+_39555993	0.268		GAST	gastrin
chr8_-_145060594	0.263	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr6_+_42531736	0.249	NM_001184801 NM_015255	UBR2	ubiquitin protein ligase E3 component n-recognin 2
chr16_-_71782165	0.249		AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr5_+_147648374	0.249	NM_001040129	SPINK13	serine peptidase inhibitor, Kazal type 13 (putative)
chr21_-_35899046	0.243	NM_203418	RCAN1	regulator of calcineurin 1
chr14_-_81864726	0.238	NM_033104	STON2	stonin 2
chr3_+_197879236	0.232	NM_001145248	FAM157A	family with sequence similarity 157, member A
chr17_-_42143937	0.231		LSM12	LSM12 homolog (S. cerevisiae)
chr17_+_76000248	0.231	NM_001142640 NM_018996	TNRC6C	trinucleotide repeat containing 6C
chr2_+_169926084	0.229		DHRS9	dehydrogenase/reductase (SDR family) member 9
chr1_+_28764660	0.226	NM_023923	PHACTR4	phosphatase and actin regulator 4
chr7_+_93535819	0.224	NM_021955	GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr5_-_16509106	0.222	NM_019000	FAM134B	family with sequence similarity 134, member B
chr6_+_131571298	0.216	NM_004842 NM_138633	AKAP7	A kinase (PRKA) anchor protein 7
chr3_-_45017600	0.211	NM_001135179 NM_016598	ZDHHC3	zinc finger, DHHC-type containing 3
chr10_+_94594469	0.210	NM_001013848	EXOC6	exocyst complex component 6
chr19_+_48828627	0.203	NM_001425	EMP3	epithelial membrane protein 3
chr6_-_51952368	0.202	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr5_-_172083569	0.200
chr21_-_31538970	0.193	NM_012131	CLDN17	claudin 17
chr2_-_47134945	0.188		MCFD2	multiple coagulation factor deficiency 2
chr1_+_79086087	0.182	NM_006820	IFI44L	interferon-induced protein 44-like
chr12_+_10183275	0.180	NM_207345	CLEC9A	C-type lectin domain family 9, member A
chr1_+_247654369	0.180	NM_001004698	OR2W5	olfactory receptor, family 2, subfamily W, member 5
chr11_-_66445318	0.175		RBM4B	RNA binding motif protein 4B
chrX_-_62780748	0.175		LOC92249	uncharacterized LOC92249
chr4_+_95376396	0.174		PDLIM5	PDZ and LIM domain 5
chr7_+_129984629	0.173	NM_001127441 NM_001127442 NM_080385	CPA5	carboxypeptidase A5
chr2_-_100046262	0.170		REV1	REV1 homolog (S. cerevisiae)
chr3_+_183770834	0.163	NM_130770	HTR3C	5-hydroxytryptamine (serotonin) receptor 3, family member C
chr11_+_28131830	0.161		METTL15	methyltransferase like 15
chr10_+_118187381	0.160	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr14_+_23789396	0.144	NM_004643	PABPN1	poly(A) binding protein, nuclear 1
chrX_-_133931146	0.144	NM_001166599 NM_001166600 NM_001170757	FAM122B	family with sequence similarity 122B
chr1_-_152061529	0.142	NM_001008536	TCHHL1	trichohyalin-like 1
chr11_-_6913730	0.139	NM_003700	OR2D2	olfactory receptor, family 2, subfamily D, member 2
chr13_-_95131718	0.139	NM_001129889 NM_001922	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)
chr7_-_44580857	0.134	NM_001101648 NM_013389	NPC1L1	NPC1 (Niemann-Pick disease, type C1, gene)-like 1
chr6_+_167704802	0.128	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr17_-_39197663	0.126	NM_030967	KRTAP1-3 KRTAP1-1	keratin associated protein 1-3 keratin associated protein 1-1
chr6_+_147524866	0.125		STXBP5	syntaxin binding protein 5 (tomosyn)
chr2_-_200213802	0.118		SATB2	SATB homeobox 2
chr5_-_142815076	0.114	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_7960201	0.107
chr3_+_151531860	0.104	NM_001086	AADAC	arylacetamide deacetylase (esterase)
chr10_-_56560947	0.103	NM_001142763 NM_001142764 NM_001142765 NM_001142766 NM_001142767 NM_001142768 NM_001142769 NM_001142770 NM_001142771 NM_001142772 NM_001142773 NM_033056	PCDH15	protocadherin-related 15
chr7_-_41742666	0.103	NM_002192	INHBA	inhibin, beta A
chrX_-_118726852	0.101	NM_001173488	NKRF	NFKB repressing factor
chr11_-_4791146	0.098	NM_001004752	OR51F1	olfactory receptor, family 51, subfamily F, member 1
chr17_-_38859976	0.091	NM_019016	KRT24	keratin 24
chr10_+_115310589	0.088	NM_001177660	HABP2	hyaluronan binding protein 2
chr20_+_42574535	0.084	NM_001098798	TOX2	TOX high mobility group box family member 2
chr12_-_10962673	0.082	NM_023917	TAS2R9	taste receptor, type 2, member 9
chr1_+_10057254	0.080	NM_052960	RBP7	retinol binding protein 7, cellular
chr21_-_32253843	0.076	NM_175858	KRTAP11-1	keratin associated protein 11-1
chr1_-_155649597	0.075	NM_001198899	YY1AP1	YY1 associated protein 1
chr10_+_86184685	0.075		FAM190B	family with sequence similarity 190, member B
chr17_-_1412995	0.074		INPP5K	inositol polyphosphate-5-phosphatase K

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
5.90	3.83e-03	GO:0002682	regulation of immune system process
4.09	1.14e-02	GO:0002376	immune system process
7.09	1.25e-02	GO:0002684	positive regulation of immune system process
7.02	1.33e-02	GO:0050776	regulation of immune response
4.58	2.81e-02	GO:0009611	response to wounding

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.34	1.02e-03	GO:0071944	cell periphery
2.27	3.20e-03	GO:0005886	plasma membrane
4.45	2.22e-02	GO:0005615	extracellular space
2.83	2.23e-02	GO:0005576	extracellular region

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
28.11	7.16e-03	GO:0043498	cell surface binding
51.51	3.00e-02	GO:0019865	immunoglobulin binding