Motif ID: POU1F1.p2

Z-value: 1.673


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU1F1hg19_v1_chr3_-_87325611_87325736-0.232.0e-01Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_196743929 12.183 NM_001166624
NM_021023
CFHR3

complement factor H-related 3

chr1_+_196857143 12.074 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr4_+_74270832 10.823 ALB
albumin
chr1_+_196946666 10.448 NM_030787
CFHR5
complement factor H-related 5
chr4_+_155484131 10.233 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr4_+_69681709 9.700 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr4_+_74269971 8.077 NM_000477
ALB
albumin
chr1_+_196912910 7.808 NM_005666
CFHR2
complement factor H-related 2
chr3_-_170744458 7.526 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr8_-_17752847 7.400 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr7_+_137761177 7.012 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr5_-_41213513 6.983 NM_000065
C6
complement component 6
chr2_-_88427535 6.814 NM_001443
FABP1
fatty acid binding protein 1, liver
chr19_-_48389514 6.670 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr4_+_74281884 6.394 ALB
albumin
chr2_+_234668914 5.932 NM_000463
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
chr2_-_88285308 5.681 NM_001024457
RGPD1
RANBP2-like and GRIP domain containing 1
chr11_+_59807747 5.639 NM_173801
PLAC1L
placenta-specific 1-like
chr2_+_211458078 5.367 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr3_-_170744529 4.980 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
Enrichment   P-value GO Accession GO Term
35.16 3.84e-02 GO:0006067 ethanol metabolic process
35.16 3.84e-02 GO:0006069 ethanol oxidation
35.16 3.84e-02 GO:0034308 primary alcohol metabolic process
32.23 3.08e-03 GO:0015721 bile acid and bile salt transport
24.40 6.11e-06 GO:0008206 bile acid metabolic process
21.49 1.71e-02 GO:0017144 drug metabolic process
18.42 4.13e-04 GO:0006956 complement activation
16.91 1.09e-05 GO:0072376 protein activation cascade
16.64 4.87e-02 GO:0006958 complement activation, classical pathway
11.64 2.28e-07 GO:0006805 xenobiotic metabolic process
11.64 2.28e-07 GO:0071466 cellular response to xenobiotic stimulus
11.55 2.49e-07 GO:0009410 response to xenobiotic stimulus
9.68 1.87e-02 GO:0006959 humoral immune response
8.25 7.27e-07 GO:0008202 steroid metabolic process
7.27 7.40e-03 GO:0002252 immune effector process
4.39 4.85e-02 GO:0032787 monocarboxylic acid metabolic process
3.83 2.22e-04 GO:0042180 cellular ketone metabolic process
3.71 7.33e-04 GO:0019752 carboxylic acid metabolic process
3.71 7.33e-04 GO:0043436 oxoacid metabolic process
3.62 1.03e-03 GO:0006082 organic acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
6.40 3.63e-05 GO:0042598 vesicular fraction
6.07 1.94e-04 GO:0005792 microsome
2.95 5.58e-03 GO:0005615 extracellular space
2.62 3.66e-02 GO:0005626 insoluble fraction
2.10 3.50e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
42.98 5.26e-03 GO:0004022 alcohol dehydrogenase (NAD) activity
23.03 3.05e-04 GO:0015020 glucuronosyltransferase activity
18.42 8.57e-03 GO:0016229 steroid dehydrogenase activity
10.40 1.63e-02 GO:0005319 lipid transporter activity
9.92 1.92e-04 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
8.90 4.39e-04 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
7.65 4.98e-03 GO:0008194 UDP-glycosyltransferase activity