Motif ID: POU3F1..4.p2

Z-value: 1.321


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU3F4hg19_v1_chrX_+_82763268_827633300.402.2e-02Click!
POU3F3hg19_v1_chr2_+_105471745_1054720510.318.7e-02Click!
POU3F1hg19_v1_chr1_-_38512446_385124530.154.2e-01Click!
POU3F2hg19_v1_chr6_+_99282597_992827480.106.0e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_40909617 9.610 C7
complement component 7
chr5_+_40909558 9.286 NM_000587
 C7
complement component 7
chrX_+_65384078 8.151 NM_001130860
NM_014799
 HEPH

hephaestin

chr6_-_46889620 7.722 NM_001098518
 GPR116
G protein-coupled receptor 116
chr12_+_100897137 6.400 NM_001206992
NM_001206993
 NR1H4

nuclear receptor subfamily 1, group H, member 4

chr12_-_91505215 6.080 LUM
lumican
chr4_+_88896838 5.485 SPP1
secreted phosphoprotein 1
chr4_+_88896868 5.478 SPP1
secreted phosphoprotein 1
chr4_-_100242487 5.191 NM_000668
 ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr5_+_150399980 5.009 NM_002084
 GPX3
glutathione peroxidase 3 (plasma)
chr2_+_189839113 4.950 COL3A1
collagen, type III, alpha 1
chrX_+_102585113 4.719 NM_152278
 TCEAL7
transcription elongation factor A (SII)-like 7
chr11_+_71903172 4.475 NM_016729
 FOLR1
folate receptor 1 (adult)
chr5_-_41213513 4.439 NM_000065
 C6
complement component 6
chr13_-_78492906 4.406 NM_001122659
NM_003991
 EDNRB

endothelin receptor type B

chr1_+_47264669 4.394 NM_000779
NM_001099772
 CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

chr13_-_78493902 4.383 NM_001201397
 EDNRB
endothelin receptor type B
chr3_-_168865521 4.201 NM_001164000
 MECOM
MDS1 and EVI1 complex locus
chr2_+_189839132 3.896 COL3A1
collagen, type III, alpha 1
chr2_+_189839078 3.847 NM_000090
 COL3A1
collagen, type III, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
45.16 8.54e-04 GO:0006067 ethanol metabolic process
45.16 8.54e-04 GO:0006069 ethanol oxidation
45.16 8.54e-04 GO:0034308 primary alcohol metabolic process
29.22 5.93e-03 GO:0007597 blood coagulation, intrinsic pathway
24.84 1.18e-02 GO:0072378 blood coagulation, fibrin clot formation
18.33 8.89e-07 GO:0072376 protein activation cascade
14.79 1.41e-02 GO:0006956 complement activation
9.32 3.02e-02 GO:0006959 humoral immune response
8.41 8.56e-04 GO:0006805 xenobiotic metabolic process
8.41 8.56e-04 GO:0071466 cellular response to xenobiotic stimulus
8.35 9.11e-04 GO:0009410 response to xenobiotic stimulus
6.27 1.02e-03 GO:0032101 regulation of response to external stimulus
3.93 3.92e-02 GO:0016477 cell migration
3.87 2.23e-02 GO:0048870 cell motility
3.87 2.23e-02 GO:0051674 localization of cell
3.75 3.06e-02 GO:0072358 cardiovascular system development
3.75 3.06e-02 GO:0072359 circulatory system development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
4.17 1.42e-07 GO:0005615 extracellular space
3.73 7.46e-08 GO:0044421 extracellular region part
2.74 7.09e-08 GO:0005576 extracellular region
2.26 4.78e-02 GO:0005887 integral to plasma membrane
1.90 4.07e-02 GO:0044459 plasma membrane part
1.76 5.78e-04 GO:0071944 cell periphery
1.75 8.52e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
55.19 8.68e-05 GO:0004022 alcohol dehydrogenase (NAD) activity
8.96 5.58e-04 GO:0008201 heparin binding
6.76 4.42e-03 GO:0005539 glycosaminoglycan binding
6.25 7.75e-03 GO:0001871 pattern binding
6.25 7.75e-03 GO:0030247 polysaccharide binding