Motif ID: PPARG.p2

Z-value: 1.223


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PPARGhg19_v1_chr3_+_12329332_123295810.086.6e-01Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_33447527 6.858 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr22_+_22758538 5.282


chr19_+_50016606 5.182 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr10_+_114135937 4.057 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_-_72362513 3.868 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr11_+_46740769 3.590 F2
coagulation factor II (thrombin)
chr2_+_219283809 3.563 NM_007127
VIL1
villin 1
chr11_+_46740736 3.489 NM_000506
F2
coagulation factor II (thrombin)
chr14_-_106208695 3.090


chr10_+_114135965 3.072 ACSL5
acyl-CoA synthetase long-chain family member 5
chr20_+_816710 2.898 NM_207121
FAM110A
family with sequence similarity 110, member A
chr14_+_105953256 2.827 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr22_+_22550112 2.713


chr6_-_52441815 2.691 NM_012288
TRAM2
translocation associated membrane protein 2
chr22_+_23229959 2.682 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_22550159 2.653 IGLV6-57
immunoglobulin lambda variable 6-57
chr22_+_23154240 2.606


chr10_+_114136014 2.556 ACSL5
acyl-CoA synthetase long-chain family member 5
chr15_-_90347173 2.547 ANPEP
alanyl (membrane) aminopeptidase
chr1_-_31230594 2.500 LAPTM5
lysosomal protein transmembrane 5
chr1_+_207925381 2.454 NM_002389
NM_153826
NM_172350
NM_172351
NM_172352
NM_172353
NM_172359
NM_172361
CD46







CD46 molecule, complement regulatory protein







chr7_+_75932865 2.249 HSPB1
heat shock 27kDa protein 1
chr12_-_121476770 2.181 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr14_-_106453162 2.165 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_100425035 2.104 NM_004444
EPHB4
EPH receptor B4
chr15_-_76603806 2.023 NM_000126
NM_001127716
ETFA

electron-transfer-flavoprotein, alpha polypeptide

chr1_+_207925409 2.008 CD46
CD46 molecule, complement regulatory protein
chr19_+_49669404 1.939 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr12_-_53600999 1.926 NM_000889
ITGB7
integrin, beta 7
chr11_-_59952138 1.891 NM_001247999
NM_152852
MS4A6A

membrane-spanning 4-domains, subfamily A, member 6A

chr15_-_76603728 1.890 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr16_+_82068958 1.799 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr15_-_76603742 1.798 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr15_-_76603791 1.784 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr11_+_2923528 1.771 SLC22A18
solute carrier family 22, member 18
chr1_-_31230673 1.764 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr11_+_46740759 1.755 F2
coagulation factor II (thrombin)
chr8_+_11351509 1.684 NM_001715
BLK
B lymphoid tyrosine kinase
chr15_-_90347534 1.639 ANPEP
alanyl (membrane) aminopeptidase
chr7_+_75932992 1.600 HSPB1
heat shock 27kDa protein 1
chr19_+_18451365 1.586 NM_017712
PGPEP1
pyroglutamyl-peptidase I
chr19_+_42388445 1.560 NM_199002
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr19_+_50016435 1.557 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr15_+_81517639 1.521 NM_172217
IL16
interleukin 16
chr1_-_236228382 1.517 NID1
nidogen 1
chr11_-_67771527 1.512 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr11_+_308106 1.460 NM_006435
IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr19_-_4540035 1.455 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr6_-_52441714 1.453 TRAM2
translocation associated membrane protein 2
chr10_-_99052429 1.452 NM_001204300
NM_032900
ARHGAP19

Rho GTPase activating protein 19

chr19_+_50016500 1.418 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr22_+_22676814 1.415


chr17_-_34207308 1.385 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr11_+_2923559 1.379 SLC22A18
solute carrier family 22, member 18
chr17_-_62097937 1.363 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr17_+_25958192 1.337 LGALS9
lectin, galactoside-binding, soluble, 9
chr1_-_159895279 1.312 NM_003564
TAGLN2
transgelin 2
chr19_+_49660997 1.298 NM_001195227
NM_017636
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr14_-_106714594 1.273


chr19_+_1000295 1.264 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr8_-_27850368 1.247 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr19_-_55740631 1.192 NM_173804
TMEM86B
transmembrane protein 86B
chr14_+_105046055 1.149 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr19_-_13213669 1.123 LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_159895258 1.098 TAGLN2
transgelin 2
chr22_-_43027436 1.095


chr8_-_9009050 1.089 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr9_+_101984558 1.053 NM_006808
SEC61B
Sec61 beta subunit
chr12_-_96390002 1.038 NM_002108
HAL
histidine ammonia-lyase
chr5_+_178977559 1.031 NM_025158
RUFY1
RUN and FYVE domain containing 1
chr11_-_5255712 1.019 NM_000519
HBD
hemoglobin, delta
chr22_+_50312333 0.970 CRELD2
cysteine-rich with EGF-like domains 2
chr11_+_14665396 0.956 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr12_-_57504935 0.955 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr22_+_50312278 0.954 NM_001135101
NM_024324
CRELD2

cysteine-rich with EGF-like domains 2

chr20_-_62610990 0.948 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr6_+_7108864 0.942 RREB1
ras responsive element binding protein 1
chr4_+_15704572 0.937 NM_004334
BST1
bone marrow stromal cell antigen 1
chr20_+_36932551 0.936 NM_001725
BPI
bactericidal/permeability-increasing protein
chr10_-_99052358 0.932 ARHGAP19
Rho GTPase activating protein 19
chr21_-_36231794 0.930 RUNX1
runt-related transcription factor 1
chr22_-_36784001 0.925 MYH9
myosin, heavy chain 9, non-muscle
chr14_+_24630421 0.920 NM_006084
IRF9
interferon regulatory factor 9
chr16_-_4466961 0.905 NM_001201479
NM_001201472
NM_001201473
NM_024535
CORO7-PAM16
CORO7


CORO7-PAM16 readthrough
coronin 7


chr9_-_130524696 0.893 NM_001142532
NM_001142531
SH2D3C

SH2 domain containing 3C

chr22_+_23165273 0.890


chr14_-_106610338 0.877 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_-_99052391 0.876 ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough
Rho GTPase activating protein 19
chr11_+_14665268 0.858 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr19_-_5839702 0.849 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr10_-_72362441 0.839 PRF1
perforin 1 (pore forming protein)
chr11_+_14665338 0.838 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr1_-_160832466 0.823 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr17_-_8815799 0.818 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr6_+_31465826 0.817 NM_005931
MICB
MHC class I polypeptide-related sequence B
chr1_-_236228374 0.811 NID1
nidogen 1
chr14_-_106994001 0.808 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr22_-_24096551 0.807 NM_013378
VPREB3
pre-B lymphocyte 3
chr3_+_46395574 0.790 CCR2
chemokine (C-C motif) receptor 2
chr22_-_36783851 0.789 MYH9
myosin, heavy chain 9, non-muscle
chr17_+_45286713 0.785 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr9_+_34329503 0.776 NM_001161
NM_001244390
NM_147172
NM_147173
NUDT2



nudix (nucleoside diphosphate linked moiety X)-type motif 2



chr3_-_170744529 0.758 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr11_+_14665308 0.754 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr1_+_155279514 0.746 FDPS
farnesyl diphosphate synthase
chr22_-_36783977 0.745 MYH9
myosin, heavy chain 9, non-muscle
chr14_-_106208537 0.743


chr11_+_75526236 0.739 UVRAG
UV radiation resistance associated gene
chr1_-_67896098 0.739 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr17_+_25958151 0.734 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr14_-_106691698 0.728


chr12_+_57849086 0.726 NM_031479
INHBE
inhibin, beta E
chr7_-_38375172 0.721 TRGV7
T cell receptor gamma variable 7 (pseudogene)
chr12_-_46384365 0.719 NM_004719
SCAF11
SR-related CTD-associated factor 11
chr16_-_28518131 0.711 NM_145659
IL27
interleukin 27
chr11_+_313852 0.705 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr11_+_75526211 0.700 NM_003369
UVRAG
UV radiation resistance associated gene
chr19_+_50016490 0.685 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr17_-_44302716 0.676 NM_001193465
KIAA1267
KIAA1267
chr1_+_150521786 0.667 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr16_-_3627353 0.655 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr7_-_134854225 0.642 NM_001243753
NM_001243755
C7orf49

chromosome 7 open reading frame 49

chr9_-_136242933 0.639 SURF4
surfeit 4
chr5_-_180076616 0.638 NM_002020
NM_182925
FLT4

fms-related tyrosine kinase 4

chr4_+_110481315 0.635 NM_017918
CCDC109B
coiled-coil domain containing 109B
chr17_+_45331218 0.614 ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr17_-_38721701 0.612 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_+_201798330 0.604 IPO9
importin 9
chr9_-_136242969 0.596 NM_033161
SURF4
surfeit 4
chr11_+_126226095 0.592 NM_006278
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr19_-_54746599 0.590 NM_024318
LILRB3
LILRA6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr8_+_98656329 0.576 NM_178812
MTDH
metadherin
chr11_+_66742747 0.574 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr19_-_4540078 0.572 LRG1
leucine-rich alpha-2-glycoprotein 1
chrX_-_107019001 0.567 NM_198057
TSC22D3
TSC22 domain family, member 3
chr9_-_117150217 0.560 AKNA
AT-hook transcription factor
chr1_+_203274646 0.558 NM_006763
BTG2
BTG family, member 2
chr17_-_39728304 0.557 NM_000226
KRT9
keratin 9
chr19_-_39368889 0.542 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr19_+_7968701 0.536 MAP2K7
mitogen-activated protein kinase kinase 7
chr22_-_36783930 0.529 MYH9
myosin, heavy chain 9, non-muscle
chr1_-_120311466 0.527 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr9_-_136242925 0.524 SURF4
surfeit 4
chr2_+_47168362 0.521 TTC7A
tetratricopeptide repeat domain 7A
chr1_-_206288646 0.511 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr6_-_31628509 0.509 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr13_-_73355969 0.504 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr15_+_69745156 0.501 NM_001003
NM_213725
RPLP1

ribosomal protein, large, P1

chr12_-_57118263 0.495 NACA
nascent polypeptide-associated complex alpha subunit
chr19_+_45452427 0.494 APOC2
apolipoprotein C-II
chr8_-_30515665 0.481 NM_002095
GTF2E2
general transcription factor IIE, polypeptide 2, beta 34kDa
chr11_+_2923487 0.476 NM_002555
SLC22A18
solute carrier family 22, member 18
chr19_+_49661031 0.475 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr16_-_21663962 0.475 NM_005849
IGSF6
immunoglobulin superfamily, member 6
chr17_+_7942351 0.462 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr11_-_320775 0.447 NM_021034
IFITM3
interferon induced transmembrane protein 3
chr19_-_49926598 0.443 NM_178449
PTH2
parathyroid hormone 2
chr11_+_2924504 0.438 SLC22A18
solute carrier family 22, member 18
chr3_+_33840077 0.435 PDCD6IP
programmed cell death 6 interacting protein
chr3_+_69812620 0.434 NM_001184967
MITF
microphthalmia-associated transcription factor
chr8_-_82024277 0.434 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr17_+_25958257 0.429 LGALS9
lectin, galactoside-binding, soluble, 9
chr1_+_16693582 0.429 NM_001114600
NM_015609
C1orf144

chromosome 1 open reading frame 144

chr1_-_47407094 0.425 CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr17_+_16318848 0.424 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr1_-_3816704 0.424 C1orf174
chromosome 1 open reading frame 174
chr1_+_158323485 0.423 NM_001042583
NM_001042584
NM_001042585
NM_001042586
NM_001042587
NM_001185107
NM_001185108
NM_001185110
NM_001185112
NM_001185113
NM_001185114
NM_001185115
NM_030893
CD1E












CD1e molecule












chrX_-_107018889 0.419 TSC22D3
TSC22 domain family, member 3
chr6_+_6588933 0.417 NM_004271
LY86
lymphocyte antigen 86
chr16_-_4466570 0.414 CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr3_-_46505077 0.411 NM_001199149
LTF
lactotransferrin
chr17_+_77704881 0.411 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chrX_-_118827060 0.407 SEPT6
septin 6
chr2_+_112813079 0.404 TMEM87B
transmembrane protein 87B
chr15_-_70341870 0.398 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr22_-_36784055 0.392 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr3_-_170744458 0.392 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr7_-_20256942 0.391 NM_182762
MACC1
metastasis associated in colon cancer 1
chr1_-_6526150 0.372 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr1_+_10459084 0.370 NM_002631
PGD
phosphogluconate dehydrogenase
chr17_-_7297826 0.365 PLSCR3
phospholipid scramblase 3
chr5_-_1494872 0.361 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr11_-_64052123 0.361 BAD
BCL2-associated agonist of cell death
chr13_-_73356058 0.353 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr2_-_32490688 0.347 NM_001199139
NM_021209
NLRC4

NLR family, CARD domain containing 4

chr17_-_38077909 0.345 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr21_-_46293598 0.345 PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr1_-_47080793 0.343 NM_145279
MOB3C
MOB kinase activator 3C
chr12_-_56122792 0.341 CD63
CD63 molecule
chr11_+_76494132 0.337 NM_015516
TSKU
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr20_-_34195409 0.335 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr18_+_29671817 0.335 NM_016271
RNF138
ring finger protein 138
chr7_+_150759633 0.331 NM_001199693
NM_001199694
SLC4A2

solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)

chr1_-_67896066 0.328 SERBP1
SERPINE1 mRNA binding protein 1
chr6_-_28891409 0.322 TRIM27
tripartite motif containing 27
chr9_-_136242818 0.320 SURF4
surfeit 4
chr17_-_40337384 0.320 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr21_-_43771069 0.310 NM_005423
TFF2
trefoil factor 2
chr1_-_32687939 0.304 TMEM234
transmembrane protein 234
chr5_-_180076599 0.297 FLT4
fms-related tyrosine kinase 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.13 2.61e-03 GO:0002376 immune system process
5.19 5.15e-03 GO:0006955 immune response
234.56 7.83e-03 GO:0002407 dendritic cell chemotaxis

Nothing significant found in compartment category.

Nothing significant found in function category.