Motif ID: RREB1.p2

Z-value: 2.567


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RREB1hg19_v1_chr6_+_7107986_7108085-0.441.1e-02Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_119249774 11.792 NM_139282
 RHOXF1
Rhox homeobox family, member 1
chr20_-_62103815 10.785 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
 KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr4_-_819879 8.949 NM_006651
 CPLX1
complexin 1
chr17_+_42385780 7.591 NM_001144825
NM_001144826
NM_006695
 RUNDC3A


RUN domain containing 3A


chrX_+_151086708 7.580 NM_001011550
 MAGEA4
melanoma antigen family A, 4
chr4_-_5890142 7.431 CRMP1
collapsin response mediator protein 1
chr2_-_97560855 7.212 NM_001172667
 FAM178B
family with sequence similarity 178, member B
chr19_+_55795766 7.149 BRSK1
BR serine/threonine kinase 1
chr1_+_1950745 6.952 NM_000815
 GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr19_+_55795533 6.619 NM_032430
 BRSK1
BR serine/threonine kinase 1
chrX_-_151903100 6.394 NM_001166386
NM_001166387
NM_005367
 MAGEA12


melanoma antigen family A, 12


chrX_+_151085396 6.323 NM_001011549
 MAGEA4
melanoma antigen family A, 4
chr19_-_47975074 6.229 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chrX_-_151938194 6.228 NM_005362
 MAGEA3
melanoma antigen family A, 3
chr5_+_6448735 5.914 NM_001145161
 UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr14_+_29236171 5.799 NM_005249
 FOXG1
forkhead box G1
chr19_-_47975244 5.779 NM_015063
 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr16_+_87636492 5.707 NM_020655
 JPH3
junctophilin 3
chr10_-_135150474 5.608 NM_015722
 CALY
calcyon neuron-specific vesicular protein
chrX_+_151903218 5.583 NM_001102576
NM_153478
 CSAG1

chondrosarcoma associated gene 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 51 entries
Enrichment   P-value GO Accession GO Term
13.87 3.12e-03 GO:0014047 glutamate secretion
11.56 1.07e-02 GO:0007214 gamma-aminobutyric acid signaling pathway
7.59 3.98e-02 GO:0030516 regulation of axon extension
6.24 1.56e-02 GO:0001764 neuron migration
4.96 4.23e-02 GO:0048638 regulation of developmental growth
4.17 4.84e-14 GO:0007268 synaptic transmission
4.16 4.21e-02 GO:0051924 regulation of calcium ion transport
4.11 5.57e-04 GO:0006813 potassium ion transport
4.03 2.84e-02 GO:0050804 regulation of synaptic transmission
3.95 4.93e-14 GO:0019226 transmission of nerve impulse
3.95 4.93e-14 GO:0035637 multicellular organismal signaling
3.92 1.89e-02 GO:0051969 regulation of transmission of nerve impulse
3.80 1.36e-02 GO:0031644 regulation of neurological system process
3.36 3.25e-02 GO:0030900 forebrain development
3.16 5.89e-08 GO:0007417 central nervous system development
3.12 5.38e-05 GO:0007420 brain development
3.09 6.36e-11 GO:0030182 neuron differentiation
3.06 4.48e-07 GO:0000904 cell morphogenesis involved in differentiation
3.04 2.31e-14 GO:0022008 neurogenesis
3.04 7.12e-06 GO:0048667 cell morphogenesis involved in neuron differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
26.01 2.47e-02 GO:0060199 clathrin sculpted glutamate transport vesicle
26.01 2.47e-02 GO:0060203 clathrin sculpted glutamate transport vesicle membrane
10.40 4.05e-03 GO:0044304 main axon
6.38 8.41e-07 GO:0008076 voltage-gated potassium channel complex
6.38 8.41e-07 GO:0034705 potassium channel complex
5.55 2.20e-02 GO:0044309 neuron spine
5.40 7.62e-08 GO:0034703 cation channel complex
4.83 4.14e-03 GO:0014069 postsynaptic density
4.69 2.50e-06 GO:0045211 postsynaptic membrane
4.67 2.91e-09 GO:0034702 ion channel complex
4.56 1.65e-02 GO:0033267 axon part
4.34 3.02e-11 GO:0044456 synapse part
4.11 7.67e-14 GO:0045202 synapse
4.06 6.75e-06 GO:0030425 dendrite
3.75 2.13e-04 GO:0030424 axon
3.55 2.04e-02 GO:0031225 anchored to membrane
3.35 3.23e-08 GO:0043005 neuron projection
2.88 1.93e-08 GO:0030054 cell junction
2.22 4.57e-02 GO:0044463 cell projection part
1.99 1.37e-03 GO:0042995 cell projection

Gene overrepresentation in function category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
34.68 8.07e-03 GO:0004965 GABA-B receptor activity
14.19 1.53e-06 GO:0016917 GABA receptor activity
10.95 3.71e-03 GO:0004890 GABA-A receptor activity
7.43 4.13e-02 GO:0008066 glutamate receptor activity
5.62 5.84e-09 GO:0022843 voltage-gated cation channel activity
5.31 4.34e-05 GO:0005249 voltage-gated potassium channel activity
4.96 7.31e-06 GO:0005267 potassium channel activity
4.82 1.32e-02 GO:0005230 extracellular ligand-gated ion channel activity
4.45 3.06e-07 GO:0005244 voltage-gated ion channel activity
4.45 3.06e-07 GO:0022832 voltage-gated channel activity
4.15 1.48e-10 GO:0022836 gated channel activity
3.94 5.03e-08 GO:0005261 cation channel activity
3.77 4.45e-11 GO:0022838 substrate-specific channel activity
3.73 1.17e-10 GO:0005216 ion channel activity
3.65 1.25e-10 GO:0015267 channel activity
3.64 1.36e-10 GO:0022803 passive transmembrane transporter activity
3.61 2.21e-02 GO:0015276 ligand-gated ion channel activity
3.61 2.21e-02 GO:0022834 ligand-gated channel activity
2.65 4.43e-06 GO:0008324 cation transmembrane transporter activity
2.56 1.67e-07 GO:0015075 ion transmembrane transporter activity