Motif ID: RREB1.p2

Z-value: 2.567


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RREB1hg19_v1_chr6_+_7107986_7108085-0.441.1e-02Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_119249774 11.792 NM_139282
RHOXF1
Rhox homeobox family, member 1
chr20_-_62103815 10.785 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr4_-_819879 8.949 NM_006651
CPLX1
complexin 1
chr17_+_42385780 7.591 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chrX_+_151086708 7.580 NM_001011550
MAGEA4
melanoma antigen family A, 4
chr4_-_5890142 7.431 CRMP1
collapsin response mediator protein 1
chr2_-_97560855 7.212 NM_001172667
FAM178B
family with sequence similarity 178, member B
chr19_+_55795766 7.149 BRSK1
BR serine/threonine kinase 1
chr1_+_1950745 6.952 NM_000815
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chr19_+_55795533 6.619 NM_032430
BRSK1
BR serine/threonine kinase 1
chrX_-_151903100 6.394 NM_001166386
NM_001166387
NM_005367
MAGEA12


melanoma antigen family A, 12


chrX_+_151085396 6.323 NM_001011549
MAGEA4
melanoma antigen family A, 4
chr19_-_47975074 6.229 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chrX_-_151938194 6.228 NM_005362
MAGEA3
melanoma antigen family A, 3
chr5_+_6448735 5.914 NM_001145161
UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr14_+_29236171 5.799 NM_005249
FOXG1
forkhead box G1
chr19_-_47975244 5.779 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr16_+_87636492 5.707 NM_020655
JPH3
junctophilin 3
chr10_-_135150474 5.608 NM_015722
CALY
calcyon neuron-specific vesicular protein
chrX_+_151903218 5.583 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chrX_-_153881757 5.572 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chrX_+_151867244 5.558 NM_005363
NM_175868
MAGEA2
MAGEA6

melanoma antigen family A, 2
melanoma antigen family A, 6

chrX_+_152224765 5.412 NM_013364
PNMA3
paraneoplastic antigen MA3
chr20_+_10199455 5.375 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr19_-_291335 5.359 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr10_-_135150368 5.318 CALY
calcyon neuron-specific vesicular protein
chr17_+_79989485 5.272 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_+_73144603 5.255 NM_004097
EMX1
empty spiracles homeobox 1
chrX_+_151081360 5.162 NM_001011548
MAGEA4
melanoma antigen family A, 4
chr19_-_49944613 5.144 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chrX_+_152224862 5.098 PNMA3
paraneoplastic antigen MA3
chr3_+_170139027 5.048 NM_001185056
CLDN11
claudin 11
chr7_-_4998744 4.828 NM_001100600
NM_198403
MMD2

monocyte to macrophage differentiation-associated 2

chrX_-_152486073 4.777 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr3_-_106959476 4.706


chr19_-_55866063 4.696 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr19_-_6502224 4.466 NM_006087
TUBB4A
tubulin, beta 4A class IVa
chrX_+_102585113 4.292 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chrX_+_102632108 4.285 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_-_151306959 4.256 NM_001204811
NM_001011543
NM_001251828
NM_021048
MAGEA10-MAGEA5
MAGEA10


MAGEA10-MAGEA5 readthrough
melanoma antigen family A, 10


chr4_-_5889992 4.226 CRMP1
collapsin response mediator protein 1
chr7_+_95401817 4.189 NM_001135556
NM_001135557
NM_004411
DYNC1I1


dynein, cytoplasmic 1, intermediate chain 1


chr4_-_5890266 4.185 NM_001313
CRMP1
collapsin response mediator protein 1
chr1_-_41131113 4.159 RIMS3
regulating synaptic membrane exocytosis 3
chr11_-_119293848 4.133 THY1
Thy-1 cell surface antigen
chr20_+_34742656 4.124 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr15_-_88799961 4.097 NM_001007156
NM_001012338
NM_001243101
NM_002530
NTRK3



neurotrophic tyrosine kinase, receptor, type 3



chr22_+_51039178 4.056 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr2_-_220173693 4.053 NM_001199764
PTPRN
protein tyrosine phosphatase, receptor type, N
chr21_+_27012067 4.041 JAM2
junctional adhesion molecule 2
chr5_+_92920592 4.018 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr12_-_49392909 3.979 NM_015086
DDN
dendrin
chr1_-_228604305 3.977 TRIM17
tripartite motif containing 17
chr7_-_100493481 3.975 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr15_-_56757239 3.931 NM_018365
MNS1
meiosis-specific nuclear structural 1
chr2_+_149633173 3.907


chrX_+_151883074 3.880 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr5_-_16179896 3.864 NM_001102562
MARCH11
membrane-associated ring finger (C3HC4) 11
chr1_-_99470177 3.860 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr13_-_37494370 3.846 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chrX_-_148669108 3.795 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chrX_-_151922329 3.776 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr22_-_44258210 3.751 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chrX_+_153813417 3.705 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr1_+_210111575 3.653 SYT14
synaptotagmin XIV
chr19_+_3880617 3.562 NM_033064
ATCAY
ataxia, cerebellar, Cayman type
chr7_-_767286 3.557 NM_001164758
NM_001164759
PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

chr19_+_3880675 3.527 ATCAY
ataxia, cerebellar, Cayman type
chr12_+_79258517 3.515 SYT1
synaptotagmin I
chr5_-_136834231 3.508 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr12_+_79258588 3.495 SYT1
synaptotagmin I
chr7_+_128432049 3.484 NM_022742
CCDC136
coiled-coil domain containing 136
chr19_-_55658310 3.469 TNNT1
troponin T type 1 (skeletal, slow)
chr19_+_589849 3.428 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chrX_+_148863592 3.421 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr22_+_51039100 3.397 NM_012324
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr19_-_46476556 3.382 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr12_+_79258794 3.380 SYT1
synaptotagmin I
chr2_+_115919512 3.348 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr4_-_46391771 3.338 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr1_+_163041694 3.336 NM_001113380
RGS4
regulator of G-protein signaling 4
chr9_+_132934685 3.320 NM_014286
NCS1
neuronal calcium sensor 1
chr16_-_30042123 3.308 NM_031478
FAM57B
family with sequence similarity 57, member B
chr7_+_101006121 3.291 NM_133457
EMID2
EMI domain containing 2
chr7_-_98467663 3.243 NM_001134450
NM_001134451
NM_152913
TMEM130


transmembrane protein 130


chrX_+_102631408 3.229 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_-_156217717 3.210 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr19_-_51071279 3.192 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chrY_+_16168097 3.169 NM_181880
NM_004679
VCY1B
VCX3A
VCY
variable charge, Y-linked 1B
variable charge, X-linked 3A
variable charge, Y-linked
chr16_+_89989686 3.147 NM_006086
TUBB3
tubulin, beta 3 class III
chr6_-_46459010 3.141 NM_001251974
RCAN2
regulator of calcineurin 2
chr6_-_29595746 3.134 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_-_55660557 3.127 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr20_+_44098392 3.101 NM_006103
WFDC2
WAP four-disulfide core domain 2
chrX_+_151084708 3.096 NM_002362
MAGEA4
melanoma antigen family A, 4
chr19_-_15090349 3.086 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr15_-_82338348 3.074 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr21_+_27011766 3.074 JAM2
junctional adhesion molecule 2
chr4_-_154710207 3.072 NM_003013
SFRP2
secreted frizzled-related protein 2
chr21_+_27012045 3.071 JAM2
junctional adhesion molecule 2
chr3_-_42744318 3.052 NM_020707
HHATL
hedgehog acyltransferase-like
chr7_-_766875 3.041 NM_001164760
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr11_-_8739398 3.035 ST5
suppression of tumorigenicity 5
chr9_-_101470836 3.026 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr21_-_10990838 3.010 NM_199259
NM_199260
NM_199261
TPTE


transmembrane phosphatase with tensin homology


chrX_-_132091223 3.004 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr5_-_142065586 3.002 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chrX_+_103031753 3.002 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr11_-_125366048 3.001 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr4_-_119273874 2.998 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr1_-_228604582 2.990 NM_001024940
NM_001134855
NM_016102
TRIM17


tripartite motif containing 17


chrX_+_103031433 2.981 NM_001128834
PLP1
proteolipid protein 1
chr3_+_192958892 2.980 NM_020386
HRASLS
HRAS-like suppressor
chr14_+_65007163 2.973 NM_021979
HSPA2
heat shock 70kDa protein 2
chrX_-_137793826 2.951 NM_004114
FGF13
fibroblast growth factor 13
chr16_+_56225301 2.931 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr2_-_220174058 2.916 PTPRN
protein tyrosine phosphatase, receptor type, N
chrY_-_16098319 2.904 NM_181880
NM_004679
VCY1B
VCX3A
VCY
variable charge, Y-linked 1B
variable charge, X-linked 3A
variable charge, Y-linked
chr11_-_790103 2.901 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chr5_+_7396030 2.893 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr10_-_98945662 2.891 NM_003061
SLIT1
slit homolog 1 (Drosophila)
chr17_+_41177247 2.867 NM_005440
RND2
Rho family GTPase 2
chr17_+_7554711 2.850 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr20_-_62130390 2.850 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr3_-_116164363 2.849 NM_002338
LSAMP
limbic system-associated membrane protein
chr19_-_35625610 2.830 LGI4
leucine-rich repeat LGI family, member 4
chr1_+_233749749 2.820 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr12_-_45444881 2.818 NM_001004329
DBX2
developing brain homeobox 2
chr2_+_42275017 2.816 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr1_+_159141376 2.811 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr12_+_79258448 2.804 NM_005639
SYT1
synaptotagmin I
chr17_-_72889704 2.803 NM_178128
FADS6
fatty acid desaturase domain family, member 6
chr19_+_708766 2.785 NM_001040134
NM_002579
PALM

paralemmin

chr22_+_51113069 2.760 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr22_+_32750871 2.734 NM_006604
RFPL3
ret finger protein-like 3
chr1_+_46669005 2.730 NM_001013615
C1orf190
chromosome 1 open reading frame 190
chr8_+_99439249 2.723 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chrX_+_100474932 2.707 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr11_+_45907198 2.707 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr2_+_233734993 2.700 NM_206895
C2orf82
chromosome 2 open reading frame 82
chrX_+_134555867 2.699 LINC00086
long intergenic non-protein coding RNA 86
chr2_+_27498288 2.699 NM_173650
DNAJC5G
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr20_-_44144263 2.676 NM_006652
SPINT3
serine peptidase inhibitor, Kunitz type, 3
chr14_+_94640648 2.672 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr12_+_56546203 2.667 NM_001199629
NM_002475
MYL6B

myosin, light chain 6B, alkali, smooth muscle and non-muscle

chr15_-_74043815 2.665 NM_001039614
C15orf59
chromosome 15 open reading frame 59
chr7_+_154002194 2.663 NM_001936
DPP6
dipeptidyl-peptidase 6
chr1_+_210111537 2.653 NM_001146261
NM_001146262
NM_001146264
NM_153262
SYT14



synaptotagmin XIV



chr19_+_55999859 2.650 NM_001144950
NM_001195267
SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chr9_+_77112251 2.649 NM_006914
RORB
RAR-related orphan receptor B
chr7_-_752083 2.639 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_-_65155965 2.634 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_-_136834418 2.625 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chrX_-_153847390 2.622 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chrX_+_154610359 2.598 NM_001017991
NM_001017990
NM_080720
H2AFB2
H2AFB1
H2AFB3
H2A histone family, member B2
H2A histone family, member B1
H2A histone family, member B3
chrX_-_137793394 2.590 FGF13
fibroblast growth factor 13
chr19_-_11564568 2.587 ELAVL3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr22_-_22901421 2.531 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr1_+_33352071 2.526 NM_002143
HPCA
hippocalcin
chr10_-_104178569 2.525 PSD
pleckstrin and Sec7 domain containing
chr13_+_111973014 2.519 NM_152324
C13orf16
chromosome 13 open reading frame 16
chr4_-_6474009 2.513 PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr1_-_208059254 2.494


chr7_+_44144002 2.491 AEBP1
AE binding protein 1
chr19_+_51815095 2.483 NM_001101372
IGLON5
IgLON family member 5
chr2_+_219824346 2.457 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr11_-_118047145 2.447 SCN2B
sodium channel, voltage-gated, type II, beta
chr13_-_102068705 2.447 NM_052867
NALCN
sodium leak channel, non-selective
chr4_-_87374282 2.412 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr1_+_36549714 2.410 TEKT2
tektin 2 (testicular)
chrX_-_70150925 2.401 NM_001048164
NM_032803
SLC7A3

solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

chrX_+_154113248 2.379 NM_001017990
NM_080720
H2AFB2
H2AFB1
H2AFB3
H2A histone family, member B2
H2A histone family, member B1
H2A histone family, member B3
chr12_+_51985016 2.374 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chrX_-_71525763 2.365 NM_001144885
NM_001144887
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr12_-_48152180 2.357 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr2_-_220174201 2.338 NM_001199763
NM_002846
PTPRN

protein tyrosine phosphatase, receptor type, N

chr15_-_83240499 2.336 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr19_+_54926604 2.332 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr12_+_70759974 2.329 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr9_-_23821477 2.323 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_752132 2.306 NM_002735
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr4_-_6474172 2.283 PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr5_-_136834887 2.281 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr8_-_110986923 2.279 NM_014379
KCNV1
potassium channel, subfamily V, member 1
chr2_+_231729623 2.266 ITM2C
integral membrane protein 2C
chr13_+_100633977 2.265 NM_007129
ZIC2
Zic family member 2
chr16_+_12995454 2.264 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr7_+_94285736 2.252 PEG10
paternally expressed 10
chr1_-_202612580 2.251 NM_001136504
SYT2
synaptotagmin II
chr16_-_755718 2.248 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr12_+_58005217 2.240 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr17_-_6459746 2.238 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr19_-_291168 2.227 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr2_+_48757063 2.217 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr10_-_61122219 2.216 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr1_+_36549675 2.211 NM_014466
TEKT2
tektin 2 (testicular)
chr19_+_55999921 2.205 SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr3_+_181429711 2.205 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr16_-_54962707 2.200 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr11_-_575848 2.194 LOC143666
uncharacterized LOC143666

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.85 3.14e-21 GO:0007399 nervous system development
3.04 2.31e-14 GO:0022008 neurogenesis
4.17 4.84e-14 GO:0007268 synaptic transmission
3.95 4.93e-14 GO:0019226 transmission of nerve impulse
3.95 4.93e-14 GO:0035637 multicellular organismal signaling
2.91 8.43e-12 GO:0048699 generation of neurons
3.09 6.36e-11 GO:0030182 neuron differentiation
2.93 2.14e-10 GO:0007267 cell-cell signaling
1.76 1.03e-09 GO:0048856 anatomical structure development
1.81 1.56e-09 GO:0048731 system development
2.60 6.08e-09 GO:0048468 cell development
1.68 1.26e-08 GO:0007275 multicellular organismal development
2.48 1.40e-08 GO:0007154 cell communication
3.16 5.89e-08 GO:0007417 central nervous system development
1.48 8.70e-08 GO:0032501 multicellular organismal process
1.90 2.11e-07 GO:0030154 cell differentiation
3.06 4.48e-07 GO:0000904 cell morphogenesis involved in differentiation
1.58 5.64e-07 GO:0032502 developmental process
2.87 6.99e-07 GO:0048666 neuron development
1.84 9.66e-07 GO:0048869 cellular developmental process
2.70 7.02e-06 GO:0000902 cell morphogenesis
3.04 7.12e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
2.63 1.08e-05 GO:0032989 cellular component morphogenesis
2.99 1.12e-05 GO:0048812 neuron projection morphogenesis
2.87 1.30e-05 GO:0031175 neuron projection development
2.29 2.10e-05 GO:0006811 ion transport
2.97 3.47e-05 GO:0007409 axonogenesis
2.53 4.75e-05 GO:0030030 cell projection organization
3.12 5.38e-05 GO:0007420 brain development
2.74 6.60e-05 GO:0048858 cell projection morphogenesis
2.72 8.23e-05 GO:0032990 cell part morphogenesis
1.89 1.07e-04 GO:0009653 anatomical structure morphogenesis
2.73 1.12e-04 GO:0030001 metal ion transport
4.11 5.57e-04 GO:0006813 potassium ion transport
2.39 1.85e-03 GO:0006812 cation transport
2.95 2.05e-03 GO:0060284 regulation of cell development
13.87 3.12e-03 GO:0014047 glutamate secretion
2.84 3.97e-03 GO:0015672 monovalent inorganic cation transport
1.68 6.79e-03 GO:0003008 system process
2.95 8.88e-03 GO:0051960 regulation of nervous system development
1.77 9.69e-03 GO:0050877 neurological system process
11.56 1.07e-02 GO:0007214 gamma-aminobutyric acid signaling pathway
3.80 1.36e-02 GO:0031644 regulation of neurological system process
6.24 1.56e-02 GO:0001764 neuron migration
3.92 1.89e-02 GO:0051969 regulation of transmission of nerve impulse
4.03 2.84e-02 GO:0050804 regulation of synaptic transmission
3.36 3.25e-02 GO:0030900 forebrain development
7.59 3.98e-02 GO:0030516 regulation of axon extension
4.16 4.21e-02 GO:0051924 regulation of calcium ion transport
4.96 4.23e-02 GO:0048638 regulation of developmental growth
2.58 4.67e-02 GO:0044057 regulation of system process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.11 7.67e-14 GO:0045202 synapse
4.34 3.02e-11 GO:0044456 synapse part
4.67 2.91e-09 GO:0034702 ion channel complex
1.87 7.62e-09 GO:0044459 plasma membrane part
2.88 1.93e-08 GO:0030054 cell junction
3.35 3.23e-08 GO:0043005 neuron projection
5.40 7.62e-08 GO:0034703 cation channel complex
6.38 8.41e-07 GO:0008076 voltage-gated potassium channel complex
6.38 8.41e-07 GO:0034705 potassium channel complex
4.69 2.50e-06 GO:0045211 postsynaptic membrane
4.06 6.75e-06 GO:0030425 dendrite
1.46 1.30e-05 GO:0005886 plasma membrane
1.44 3.54e-05 GO:0071944 cell periphery
1.31 7.79e-05 GO:0044425 membrane part
1.88 1.78e-04 GO:0031226 intrinsic to plasma membrane
1.89 1.98e-04 GO:0005887 integral to plasma membrane
3.75 2.13e-04 GO:0030424 axon
1.99 1.37e-03 GO:0042995 cell projection
1.31 1.73e-03 GO:0031224 intrinsic to membrane
1.23 2.66e-03 GO:0016020 membrane
10.40 4.05e-03 GO:0044304 main axon
4.83 4.14e-03 GO:0014069 postsynaptic density
4.56 1.65e-02 GO:0033267 axon part
3.55 2.04e-02 GO:0031225 anchored to membrane
5.55 2.20e-02 GO:0044309 neuron spine
26.01 2.47e-02 GO:0060199 clathrin sculpted glutamate transport vesicle
26.01 2.47e-02 GO:0060203 clathrin sculpted glutamate transport vesicle membrane
1.26 4.45e-02 GO:0016021 integral to membrane
2.22 4.57e-02 GO:0044463 cell projection part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.77 4.45e-11 GO:0022838 substrate-specific channel activity
3.73 1.17e-10 GO:0005216 ion channel activity
3.65 1.25e-10 GO:0015267 channel activity
3.64 1.36e-10 GO:0022803 passive transmembrane transporter activity
4.15 1.48e-10 GO:0022836 gated channel activity
5.62 5.84e-09 GO:0022843 voltage-gated cation channel activity
3.94 5.03e-08 GO:0005261 cation channel activity
2.56 1.67e-07 GO:0015075 ion transmembrane transporter activity
4.45 3.06e-07 GO:0005244 voltage-gated ion channel activity
4.45 3.06e-07 GO:0022832 voltage-gated channel activity
14.19 1.53e-06 GO:0016917 GABA receptor activity
2.65 4.43e-06 GO:0008324 cation transmembrane transporter activity
2.27 4.69e-06 GO:0022891 substrate-specific transmembrane transporter activity
4.96 7.31e-06 GO:0005267 potassium channel activity
2.19 9.77e-06 GO:0022857 transmembrane transporter activity
5.31 4.34e-05 GO:0005249 voltage-gated potassium channel activity
1.99 2.76e-04 GO:0022892 substrate-specific transporter activity
1.89 2.81e-04 GO:0005215 transporter activity
10.95 3.71e-03 GO:0004890 GABA-A receptor activity
34.68 8.07e-03 GO:0004965 GABA-B receptor activity
4.82 1.32e-02 GO:0005230 extracellular ligand-gated ion channel activity
3.61 2.21e-02 GO:0015276 ligand-gated ion channel activity
3.61 2.21e-02 GO:0022834 ligand-gated channel activity
7.43 4.13e-02 GO:0008066 glutamate receptor activity