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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: RUNX1..3.p2

Z-value: 5.717

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_114414245	29.288	NM_001193431 NM_012411 NM_015967	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr21_-_36421558	27.791		RUNX1	runt-related transcription factor 1
chr1_-_25291474	24.713	NM_001031680	RUNX3	runt-related transcription factor 3
chr11_+_60739114	24.347	NM_006725	CD6	CD6 molecule
chr16_+_29674568	23.229	NM_003123	SPN	sialophorin
chr6_+_45296053	22.492	NM_001015051 NM_001024630	RUNX2	runt-related transcription factor 2
chr17_-_29641094	21.175	NM_006495	EVI2B	ecotropic viral integration site 2B
chr6_-_128222175	20.999	NM_001010923 NM_001164685	THEMIS	thymocyte selection associated
chr1_-_168513201	20.429	NM_003175	XCL1 XCL2	chemokine (C motif) ligand 1 chemokine (C motif) ligand 2
chr12_-_68553322	20.320	NM_000619	IFNG	interferon, gamma
chr21_-_36421578	20.030		RUNX1	runt-related transcription factor 1
chr17_-_29641068	19.595		EVI2B	ecotropic viral integration site 2B
chr2_-_158300517	19.316	NM_004288	CYTIP	cytohesin 1 interacting protein
chr4_+_71091787	19.183	NM_152997	C4orf7	chromosome 4 open reading frame 7
chr6_-_32163299	18.855	NM_022107	GPSM3	G-protein signaling modulator 3
chr21_-_36421461	18.320		RUNX1	runt-related transcription factor 1
chr17_-_29641087	17.918		EVI2B	ecotropic viral integration site 2B
chr12_-_10542616	17.656	NM_007360	KLRK1	killer cell lectin-like receptor subfamily K, member 1
chr4_-_84035888	17.634		PLAC8	placenta-specific 8
chr4_-_84035908	17.431	NM_001130715 NM_016619	PLAC8	placenta-specific 8
chr1_+_209929378	17.348	NM_025228	TRAF3IP3	TRAF3 interacting protein 3
chr5_+_35856990	17.207	NM_002185	IL7R	interleukin 7 receptor
chr1_+_206730591	16.926		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr16_+_29674564	16.855		SPN	sialophorin
chr14_-_106780535	16.848		IGHA1 IGHA2 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_-_150920946	16.643	NM_013308	GPR171	G protein-coupled receptor 171
chr1_+_198608244	16.572		PTPRC	protein tyrosine phosphatase, receptor type, C
chr16_-_68033355	16.493	NM_022355	DPEP2	dipeptidase 2
chr11_-_58343308	16.099	NM_004811	LPXN	leupaxin
chr17_-_34524054	15.990	NM_001001437 NM_021006	CCL3L3 CCL3 CCL3L1	chemokine (C-C motif) ligand 3-like 3 chemokine (C-C motif) ligand 3 chemokine (C-C motif) ligand 3-like 1
chr1_+_198608216	15.710		PTPRC	protein tyrosine phosphatase, receptor type, C
chr4_-_71532341	15.544	NM_144646	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_204571197	15.343	NM_001243077 NM_001243078 NM_006139	CD28	CD28 molecule
chr4_-_71532206	15.221		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_198608136	15.172	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr1_+_206730893	15.101		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr1_+_32716839	14.993	NM_005356	LCK	lymphocyte-specific protein tyrosine kinase
chr11_-_67205151	14.795	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr21_-_36421195	14.448		RUNX1	runt-related transcription factor 1
chr21_-_36421586	14.309	NM_001754	RUNX1	runt-related transcription factor 1
chr1_+_172628157	14.306	NM_000639	FASLG	Fas ligand (TNF superfamily, member 6)
chr2_+_204571379	14.209		CD28	CD28 molecule
chrX_+_78200828	13.879	NM_014499 NM_198333	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chrX_-_30595883	13.794	NM_025159	CXorf21	chromosome X open reading frame 21
chr15_-_22473092	13.659
chr22_-_37640287	13.642	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_-_160832466	13.542	NM_001166663 NM_001166664 NM_016382	CD244	CD244 molecule, natural killer cell receptor 2B4
chr11_+_65647283	13.514	NM_001335	CTSW	cathepsin W
chr19_-_42636559	13.358	NM_001207025 NM_001207026 NM_001247994 NM_002698	POU2F2	POU class 2 homeobox 2
chr22_+_23054862	13.163		IGLV3-21 IGLJ3 IGLC1	immunoglobulin lambda variable 3-21 immunoglobulin lambda joining 3 immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_40297085	13.017	NM_004810	GRAP2	GRB2-related adaptor protein 2
chr9_-_130540911	12.963	NM_170600	SH2D3C	SH2 domain containing 3C
chrX_-_49121171	12.918	NM_001114377 NM_014009	FOXP3	forkhead box P3
chr20_+_44637539	12.852	NM_004994	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr2_+_85921413	12.795	NM_006433 NM_012483	GNLY	granulysin
chr1_+_17634689	12.753	NM_012387	PADI4	peptidyl arginine deiminase, type IV
chr6_+_31543340	12.731	NM_000594	TNF	tumor necrosis factor
chrX_-_70838298	12.653	NM_001142797 NM_001504	CXCR3	chemokine (C-X-C motif) receptor 3
chr1_+_168545710	12.554	NM_002995	XCL1	chemokine (C motif) ligand 1
chr16_+_23847271	12.396	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr22_+_23154240	12.253
chr1_+_203734283	12.243	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr4_-_38858407	12.205	NM_006068	TLR6	toll-like receptor 6
chr16_+_23847321	12.202		PRKCB	protein kinase C, beta
chr20_-_1600589	12.196	NM_001083910 NM_001135844 NM_006065	SIRPB1	signal-regulatory protein beta 1
chr11_+_1889902	12.188	NM_001013253	LSP1	lymphocyte-specific protein 1
chr16_+_31366468	12.073	NM_000887	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_+_90077732	11.929
chr12_+_47610244	11.706		FAM113B	family with sequence similarity 113, member B
chr21_-_36421630	11.531		RUNX1	runt-related transcription factor 1
chr16_+_72088507	11.360	NM_001126102 NM_005143	HP	haptoglobin
chr14_+_93118576	11.352		RIN3	Ras and Rab interactor 3
chr6_-_41168923	11.326	NM_024807	TREML2	triggering receptor expressed on myeloid cells-like 2
chr8_-_21771111	11.042	NM_003974	DOK2	docking protein 2, 56kDa
chr19_+_17634109	11.010	NM_001098524 NM_173544	FAM129C	family with sequence similarity 129, member C
chr16_+_29674282	11.004	NM_001030288	SPN	sialophorin
chr17_-_34417386	10.997	NM_002983	CCL3	chemokine (C-C motif) ligand 3
chr1_+_53099015	10.996	NM_001042693	FAM159A	family with sequence similarity 159, member A
chr17_-_73840495	10.893		UNC13D	unc-13 homolog D (C. elegans)
chr16_+_30194925	10.888		CORO1A	coronin, actin binding protein, 1A
chr22_+_23222897	10.848		CYAT1	immunoglobulin lambda light chain-like
chr8_-_126963395	10.846		LOC100130231	uncharacterized LOC100130231
chr19_-_14785626	10.842	NM_032571	EMR3	egf-like module containing, mucin-like, hormone receptor-like 3
chr22_+_22786283	10.838
chr8_-_134072404	10.793	NM_006748	SLA	Src-like-adaptor
chr19_+_51645556	10.774	NM_014385 NM_016543	SIGLEC7	sialic acid binding Ig-like lectin 7
chr22_+_22712091	10.714		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr22_-_37640187	10.692		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr17_-_73840587	10.581	NM_199242	UNC13D	unc-13 homolog D (C. elegans)
chr14_-_106478129	10.534		IGHV4-31 IGHD IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr20_+_54987167	10.520	NM_001164116 NM_001164114 NM_001164115 NM_020356	CASS4	Cas scaffolding protein family member 4
chr1_+_206643830	10.476		IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr14_-_107083398	10.471		IGH@ IGHA1 IGHG1	immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_45810609	10.463	NM_013351	TBX21	T-box 21
chr1_-_157522151	10.351	NM_001195388 NM_031281	FCRL5	Fc receptor-like 5
chr11_+_122709205	10.210	NM_019604	CRTAM	cytotoxic and regulatory T cell molecule
chr2_+_103035148	10.181	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr22_+_40297183	10.167		GRAP2	GRB2-related adaptor protein 2
chr5_+_54398473	10.134	NM_006144	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr1_-_92951593	10.058	NM_001127216	GFI1	growth factor independent 1 transcription repressor
chr1_+_206643786	9.990		IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr1_-_161039413	9.924		ARHGAP30	Rho GTPase activating protein 30
chr2_-_89165652	9.868
chr9_-_117692874	9.836	NM_001244 NM_001252290	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8
chr2_-_73928466	9.836	NM_016347	NAT8B	N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
chr4_-_74847669	9.684	NM_002619	PF4	platelet factor 4
chr1_-_161039745	9.632	NM_001025598 NM_181720	ARHGAP30	Rho GTPase activating protein 30
chr2_+_204732509	9.594	NM_001037631 NM_005214	CTLA4	cytotoxic T-lymphocyte-associated protein 4
chr19_-_50868877	9.511	NM_004851	NAPSA	napsin A aspartic peptidase
chr14_-_106829736	9.394		IGHA1 IGHD IGHG3 IGHM SKAP2	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu src kinase associated phosphoprotein 2
chr2_-_175462428	9.391		WIPF1	WAS/WASL interacting protein family, member 1
chr1_-_207095198	9.362	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr1_-_161039649	9.361		ARHGAP30	Rho GTPase activating protein 30
chr14_+_75988765	9.153	NM_006399	BATF	basic leucine zipper transcription factor, ATF-like
chr5_-_39203061	9.142		FYB	FYN binding protein
chr1_+_32739711	9.138	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase
chr6_+_31540092	9.089	NM_000595	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr19_+_16254454	9.080		HSH2D	hematopoietic SH2 domain containing
chr12_+_105153258	9.061		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr5_-_39219578	9.060	NM_001465 NM_199335	FYB	FYN binding protein
chr10_-_6104113	9.014	NM_000417	IL2RA	interleukin 2 receptor, alpha
chr16_+_23847496	8.995		PRKCB	protein kinase C, beta
chr1_+_206730497	8.979		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr5_-_39270708	8.917	NM_001243093	FYB	FYN binding protein
chr14_+_75988838	8.713		BATF	basic leucine zipper transcription factor, ATF-like
chr3_-_151047309	8.684	NM_176894	P2RY13	purinergic receptor P2Y, G-protein coupled, 13
chr13_-_28674646	8.601	NM_004119	FLT3	fms-related tyrosine kinase 3
chr1_+_206730456	8.587	NM_182665	RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr17_-_72542244	8.478	NM_006678	CD300C	CD300c molecule
chr1_-_161039586	8.461		ARHGAP30	Rho GTPase activating protein 30
chr22_-_37975937	8.460	NM_006498	LGALS2	lectin, galactoside-binding, soluble, 2
chrX_+_48542193	8.452		WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr5_-_140895407	8.420		DIAPH1	diaphanous homolog 1 (Drosophila)
chr1_-_161039703	8.375		ARHGAP30	Rho GTPase activating protein 30
chr6_-_32784727	8.367	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr9_+_95709600	8.277	NM_001083536	FGD3	FYVE, RhoGEF and PH domain containing 3
chr11_-_128457452	8.259	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr10_+_70847857	8.156		SRGN	serglycin
chr2_+_182321618	8.136	NM_000885	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr3_+_98250742	8.031	NM_005290	GPR15	G protein-coupled receptor 15
chr16_+_23847359	7.980		PRKCB	protein kinase C, beta
chr20_-_35274557	7.960	NM_032214 NM_175077	SLA2	Src-like-adaptor 2
chr19_+_55085273	7.940		LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr3_+_114012832	7.781	NM_173799	TIGIT	T cell immunoreceptor with Ig and ITIM domains
chr1_-_157670280	7.724	NM_052939	FCRL3	Fc receptor-like 3
chr13_-_46756295	7.624		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_29648631	7.617	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr13_-_46756291	7.606		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_38806410	7.450	NM_003263	TLR1	toll-like receptor 1
chr10_+_70847817	7.439	NM_002727	SRGN	serglycin
chr5_-_176326314	7.425	NM_002115	HK3	hexokinase 3 (white cell)
chr1_-_27732069	7.419		WASF2	WAS protein family, member 2
chr11_-_58345593	7.376	NM_001143995	LPXN	leupaxin
chr9_-_86584079	7.223		HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr18_+_21572736	7.199	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr11_+_35198199	7.170		CD44	CD44 molecule (Indian blood group)
chr11_+_36397534	7.094	NM_001160168 NM_024841	PRR5L	proline rich 5 like
chrX_+_48542159	7.065	NM_000377	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr9_-_123688352	6.962		TRAF1	TNF receptor-associated factor 1
chr9_-_130517552	6.882	NM_001142534 NM_001142533	SH2D3C	SH2 domain containing 3C
chr17_-_72542148	6.879		CD300C	CD300c molecule
chr1_-_169680677	6.872	NM_000655	SELL	selectin L
chr14_-_106691698	6.852
chr16_+_27438578	6.838	NM_021798	IL21R	interleukin 21 receptor
chr2_-_89442551	6.745		IGKC IGK@	immunoglobulin kappa constant immunoglobulin kappa locus
chr4_-_153601085	6.682	NM_152680	TMEM154	transmembrane protein 154
chr6_-_149806116	6.679	NM_207360	ZC3H12D	zinc finger CCCH-type containing 12D
chr16_+_28505920	6.649	NM_018690	APOBR	apolipoprotein B receptor
chr1_+_206643585	6.558	NM_001193321 NM_001193322 NM_014002	IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr1_-_159046555	6.556	NM_004833	AIM2	absent in melanoma 2
chr1_+_26872306	6.554		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr3_-_71834187	6.471	NM_001126128 NM_021935	PROK2	prokineticin 2
chr19_-_36233311	6.414	NM_024660	IGFLR1	IGF-like family receptor 1
chr14_+_93118793	6.403		RIN3	Ras and Rab interactor 3
chr19_+_2289996	6.386
chr19_-_18197632	6.382	NM_005535 NM_153701	IL12RB1	interleukin 12 receptor, beta 1
chrX_-_19817907	6.316	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr17_+_72462521	6.314	NM_007261	CD300A	CD300a molecule
chr5_+_176784947	6.232
chr14_+_21423627	6.228	NM_002934	RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chrX_-_47489703	6.224	NM_002621	CFP	complement factor properdin
chr2_+_128175989	6.174	NM_000312	PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr12_+_93130264	6.099	NM_001004330	PLEKHG7	pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr22_+_23134980	6.076
chr22_-_24096551	6.067	NM_013378	VPREB3	pre-B lymphocyte 3
chr11_+_36422546	5.994	NM_001160169	PRR5L	proline rich 5 like
chrX_-_19817854	5.991		SH3KBP1	SH3-domain kinase binding protein 1
chr22_+_39378404	5.982	NM_004900	APOBEC3D APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr20_-_1638359	5.961	NM_001039508 NM_018556 NM_080816	SIRPG	signal-regulatory protein gamma
chr7_+_2552162	5.961	NM_001166355	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_182322265	5.938		ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr12_+_10457044	5.934	NM_001114396	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr21_-_36260086	5.908		RUNX1	runt-related transcription factor 1
chr11_-_5275904	5.893	NM_000184	HBG1 HBG2	hemoglobin, gamma A hemoglobin, gamma G
chr12_+_9980076	5.880	NM_016523	KLRF1	killer cell lectin-like receptor subfamily F, member 1
chr19_-_54746599	5.868	NM_024318	LILRB3 LILRA6	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr19_+_42300521	5.809	NM_001815	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3
chr11_+_64107687	5.716	NM_032251	CCDC88B	coiled-coil domain containing 88B
chr19_-_44285012	5.696		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr6_+_31539875	5.665	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.94	5.35e-47	GO:0002376	immune system process
4.48	4.98e-36	GO:0006955	immune response
3.80	1.54e-22	GO:0002682	regulation of immune system process
3.53	2.09e-22	GO:0006952	defense response
1.63	4.65e-22	GO:0050896	response to stimulus
1.94	1.52e-19	GO:0007165	signal transduction
4.17	2.36e-19	GO:0001775	cell activation
1.83	2.02e-17	GO:0023052	signaling
2.10	5.38e-17	GO:0006950	response to stress
6.09	3.04e-16	GO:0046649	lymphocyte activation
2.27	1.42e-15	GO:0007166	cell surface receptor linked signaling pathway
2.95	1.95e-15	GO:0009611	response to wounding
4.00	2.04e-15	GO:0002684	positive regulation of immune system process
3.96	3.21e-15	GO:0050776	regulation of immune response
1.72	3.40e-15	GO:0051716	cellular response to stimulus
2.20	1.34e-14	GO:0048583	regulation of response to stimulus
5.15	1.71e-14	GO:0045321	leukocyte activation
4.88	3.14e-13	GO:0050865	regulation of cell activation
4.48	1.09e-12	GO:0050778	positive regulation of immune response
4.81	3.04e-12	GO:0002694	regulation of leukocyte activation
2.72	1.29e-10	GO:0048584	positive regulation of response to stimulus
4.72	1.80e-10	GO:0051249	regulation of lymphocyte activation
4.59	4.14e-10	GO:0002253	activation of immune response
4.05	3.31e-09	GO:0001817	regulation of cytokine production
4.85	7.12e-09	GO:0002757	immune response-activating signal transduction
1.33	9.44e-09	GO:0065007	biological regulation
1.35	1.20e-08	GO:0050789	regulation of biological process
4.74	1.27e-08	GO:0002764	immune response-regulating signaling pathway
3.46	1.48e-08	GO:0045087	innate immune response
1.36	3.25e-08	GO:0050794	regulation of cellular process
3.04	3.67e-08	GO:0007596	blood coagulation
3.04	3.67e-08	GO:0050817	coagulation
3.02	4.61e-08	GO:0007599	hemostasis
5.72	5.36e-08	GO:0042110	T cell activation
1.71	7.40e-08	GO:0048518	positive regulation of biological process
4.84	2.67e-07	GO:0002697	regulation of immune effector process
2.76	3.84e-07	GO:0050878	regulation of body fluid levels
4.46	6.53e-07	GO:0050863	regulation of T cell activation
3.57	8.74e-07	GO:0006954	inflammatory response
3.02	1.58e-06	GO:0007243	intracellular protein kinase cascade
3.02	1.58e-06	GO:0023014	signal transduction via phosphorylation event
2.77	1.98e-06	GO:0080134	regulation of response to stress
7.29	2.24e-06	GO:0050866	negative regulation of cell activation
3.25	5.15e-06	GO:0031347	regulation of defense response
7.41	6.38e-06	GO:0002695	negative regulation of leukocyte activation
5.50	6.65e-06	GO:0002683	negative regulation of immune system process
6.74	7.31e-06	GO:0002703	regulation of leukocyte mediated immunity
4.41	9.68e-06	GO:0050900	leukocyte migration
5.66	1.14e-05	GO:0001818	negative regulation of cytokine production
2.55	1.16e-05	GO:0042060	wound healing
4.16	1.37e-05	GO:0051251	positive regulation of lymphocyte activation
3.97	1.60e-05	GO:0050867	positive regulation of cell activation
1.95	2.72e-05	GO:0051239	regulation of multicellular organismal process
6.01	3.87e-05	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
3.45	4.15e-05	GO:0051241	negative regulation of multicellular organismal process
7.73	5.07e-05	GO:0032675	regulation of interleukin-6 production
3.87	5.33e-05	GO:0002696	positive regulation of leukocyte activation
5.85	5.66e-05	GO:0002250	adaptive immune response
6.88	6.13e-05	GO:0002706	regulation of lymphocyte mediated immunity
4.33	1.42e-04	GO:0001819	positive regulation of cytokine production
1.60	1.94e-04	GO:0048522	positive regulation of cellular process
4.99	2.05e-04	GO:0030098	lymphocyte differentiation
4.20	2.33e-04	GO:0050870	positive regulation of T cell activation
1.85	2.38e-04	GO:0035556	intracellular signal transduction
4.30	3.49e-04	GO:0002521	leukocyte differentiation
4.74	4.28e-04	GO:0050670	regulation of lymphocyte proliferation
4.70	4.93e-04	GO:0002429	immune response-activating cell surface receptor signaling pathway
4.70	4.93e-04	GO:0032944	regulation of mononuclear cell proliferation
7.09	5.12e-04	GO:0032649	regulation of interferon-gamma production
6.35	5.35e-04	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
6.24	6.57e-04	GO:0002819	regulation of adaptive immune response
4.56	7.45e-04	GO:0070663	regulation of leukocyte proliferation
4.52	8.52e-04	GO:0002768	immune response-regulating cell surface receptor signaling pathway
4.78	9.17e-04	GO:0050851	antigen receptor-mediated signaling pathway
3.03	9.81e-04	GO:0048534	hemopoietic or lymphoid organ development
6.65	1.02e-03	GO:0051250	negative regulation of lymphocyte activation
8.60	1.06e-03	GO:0031341	regulation of cell killing
16.16	1.10e-03	GO:0050710	negative regulation of cytokine secretion
2.92	1.26e-03	GO:0002520	immune system development
12.20	1.33e-03	GO:0050709	negative regulation of protein secretion
5.35	1.40e-03	GO:0042113	B cell activation
2.41	1.47e-03	GO:0048585	negative regulation of response to stimulus
8.08	1.91e-03	GO:0046651	lymphocyte proliferation
1.56	2.06e-03	GO:0048519	negative regulation of biological process
14.81	2.14e-03	GO:0032715	negative regulation of interleukin-6 production
5.14	2.28e-03	GO:0002699	positive regulation of immune effector process
1.89	2.29e-03	GO:0010941	regulation of cell death
2.30	2.30e-03	GO:0006928	cellular component movement
6.04	2.88e-03	GO:0006968	cellular defense response
3.10	3.09e-03	GO:0030168	platelet activation
7.62	3.28e-03	GO:0032943	mononuclear cell proliferation
4.09	3.36e-03	GO:0042742	defense response to bacterium
3.52	3.77e-03	GO:0031349	positive regulation of defense response
8.78	3.86e-03	GO:0032655	regulation of interleukin-12 production
8.78	3.86e-03	GO:0032729	positive regulation of interferon-gamma production
7.41	4.25e-03	GO:0070661	leukocyte proliferation
6.44	4.61e-03	GO:0002700	regulation of production of molecular mediator of immune response
6.44	4.61e-03	GO:0032680	regulation of tumor necrosis factor production
4.19	5.08e-03	GO:0007204	elevation of cytosolic calcium ion concentration
8.47	5.24e-03	GO:0001910	regulation of leukocyte mediated cytotoxicity
3.00	5.29e-03	GO:0030097	hemopoiesis
1.94	5.60e-03	GO:0051704	multi-organism process
5.15	5.66e-03	GO:0002449	lymphocyte mediated immunity
2.94	7.65e-03	GO:0000165	MAPKKK cascade
1.55	7.86e-03	GO:0048523	negative regulation of cellular process
5.43	8.58e-03	GO:0050864	regulation of B cell activation
6.84	8.74e-03	GO:0050868	negative regulation of T cell activation
1.84	9.56e-03	GO:0042981	regulation of apoptosis
2.43	1.03e-02	GO:0051707	response to other organism
23.70	1.19e-02	GO:0002710	negative regulation of T cell mediated immunity
1.83	1.24e-02	GO:0043067	regulation of programmed cell death
2.85	1.26e-02	GO:0009617	response to bacterium
2.25	1.36e-02	GO:0009607	response to biotic stimulus
7.41	1.57e-02	GO:0050777	negative regulation of immune response
6.35	1.68e-02	GO:0045639	positive regulation of myeloid cell differentiation
1.91	1.71e-02	GO:0040011	locomotion
4.62	1.85e-02	GO:0042035	regulation of cytokine biosynthetic process
8.64	1.93e-02	GO:0002637	regulation of immunoglobulin production
3.74	2.17e-02	GO:0051480	cytosolic calcium ion homeostasis
2.62	2.28e-02	GO:0034097	response to cytokine stimulus
4.19	2.38e-02	GO:0002758	innate immune response-activating signal transduction
10.46	2.48e-02	GO:0030101	natural killer cell activation
1.52	2.53e-02	GO:0065008	regulation of biological quality
8.30	2.60e-02	GO:0002763	positive regulation of myeloid leukocyte differentiation
4.10	3.02e-02	GO:0002218	activation of innate immune response
1.66	3.20e-02	GO:0009966	regulation of signal transduction
4.72	3.47e-02	GO:0050708	regulation of protein secretion
19.75	3.49e-02	GO:0002820	negative regulation of adaptive immune response
19.75	3.49e-02	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
9.88	3.61e-02	GO:0032653	regulation of interleukin-10 production
2.91	3.80e-02	GO:0071345	cellular response to cytokine stimulus
3.34	4.67e-02	GO:0002252	immune effector process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.61	4.30e-12	GO:0005886	plasma membrane
1.59	1.01e-11	GO:0071944	cell periphery
1.85	5.95e-10	GO:0044459	plasma membrane part
2.07	5.91e-08	GO:0005887	integral to plasma membrane
2.06	6.19e-08	GO:0031226	intrinsic to plasma membrane
2.35	2.28e-07	GO:0005615	extracellular space
1.34	6.02e-07	GO:0044425	membrane part
1.37	3.82e-06	GO:0016021	integral to membrane
1.69	4.42e-06	GO:0005576	extracellular region
1.35	8.46e-06	GO:0031224	intrinsic to membrane
1.26	1.35e-05	GO:0016020	membrane
4.08	4.80e-05	GO:0009897	external side of plasma membrane
1.93	9.78e-05	GO:0044421	extracellular region part
2.44	1.70e-03	GO:0009986	cell surface
22.22	3.65e-02	GO:0070382	exocytic vesicle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.97	7.01e-12	GO:0004871	signal transducer activity
1.97	7.01e-12	GO:0060089	molecular transducer activity
2.01	4.12e-10	GO:0004872	receptor activity
10.37	7.61e-09	GO:0003823	antigen binding
4.28	2.87e-08	GO:0005125	cytokine activity
4.12	6.74e-07	GO:0005126	cytokine receptor binding
3.74	9.44e-06	GO:0005529	sugar binding
12.48	3.03e-05	GO:0005164	tumor necrosis factor receptor binding
6.97	3.22e-05	GO:0042379	chemokine receptor binding
1.85	6.28e-05	GO:0004888	transmembrane receptor activity
7.09	9.30e-05	GO:0008009	chemokine activity
2.68	9.97e-05	GO:0030246	carbohydrate binding
3.62	1.25e-04	GO:0001664	G-protein-coupled receptor binding
1.93	1.81e-04	GO:0005102	receptor binding
6.05	1.54e-03	GO:0005070	SH3/SH2 adaptor activity
7.65	2.21e-03	GO:0032813	tumor necrosis factor receptor superfamily binding
4.94	1.01e-02	GO:0035591	signaling adaptor activity