Motif ID: RXR{A,B,G}.p2

Z-value: 1.496


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RXRGhg19_v1_chr1_-_165414499_1654145910.345.9e-02Click!
RXRBhg19_v1_chr6_-_33168448_331684500.336.2e-02Click!
RXRAhg19_v1_chr9_+_137218324_1372184770.193.0e-01Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_7184978 6.021 NM_001042
 SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr7_+_116166346 4.783 NM_001172896
NM_001172897
 CAV1

caveolin 1, caveolae protein, 22kDa

chr19_-_49658645 4.538 NM_002152
 HRC
histidine rich calcium binding protein
chr11_-_2017822 3.854 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr11_-_2018446 3.767 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr12_+_54378929 3.767 NM_017409
 HOXC10
homeobox C10
chr19_-_36246411 3.556 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr11_-_2018334 3.261 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr19_-_36246206 3.003 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr2_+_27301693 2.879 EMILIN1
elastin microfibril interfacer 1
chr2_+_42275017 2.858 NM_138370
 PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr14_-_61190458 2.825 NM_017420
 SIX4
SIX homeobox 4
chr6_+_43738394 2.758 VEGFA
vascular endothelial growth factor A
chr6_+_43737937 2.740 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
 VEGFA

















vascular endothelial growth factor A

















chr3_-_123167391 2.736 NM_183357
 ADCY5
adenylate cyclase 5
chr12_-_54982271 2.719 NM_006741
 PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr1_+_202317798 2.716 NM_001167857
NM_001167858
NM_002481
 PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr15_+_41221530 2.713 NM_019074
 DLL4
delta-like 4 (Drosophila)
chr5_-_172755195 2.685 STC2
stanniocalcin 2
chr19_+_16999871 2.634 F2RL3
coagulation factor II (thrombin) receptor-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 34 entries
Enrichment   P-value GO Accession GO Term
130.91 4.64e-02 GO:0001765 membrane raft assembly
130.91 4.64e-02 GO:0030214 hyaluronan catabolic process
130.91 4.64e-02 GO:0070836 caveola assembly
15.59 1.27e-02 GO:0001570 vasculogenesis
11.56 1.02e-02 GO:0006937 regulation of muscle contraction
10.34 1.93e-02 GO:0090257 regulation of muscle system process
7.38 1.01e-02 GO:0045165 cell fate commitment
7.07 3.49e-04 GO:0048514 blood vessel morphogenesis
6.84 4.31e-05 GO:0001568 blood vessel development
6.41 9.00e-03 GO:0007517 muscle organ development
6.36 1.02e-04 GO:0001944 vasculature development
6.22 4.25e-05 GO:0001501 skeletal system development
5.06 2.27e-02 GO:0061061 muscle structure development
4.87 1.34e-04 GO:0072358 cardiovascular system development
4.87 1.34e-04 GO:0072359 circulatory system development
4.72 4.13e-02 GO:0048729 tissue morphogenesis
4.67 1.89e-02 GO:0044057 regulation of system process
4.23 4.64e-02 GO:0048598 embryonic morphogenesis
4.11 5.77e-04 GO:0009887 organ morphogenesis
3.78 9.05e-04 GO:0009790 embryo development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
20.68 4.70e-02 GO:0005811 lipid particle
4.72 4.48e-04 GO:0031012 extracellular matrix
4.29 1.41e-02 GO:0005578 proteinaceous extracellular matrix
2.71 4.85e-03 GO:0044421 extracellular region part
2.66 3.88e-02 GO:0005626 insoluble fraction
2.41 3.68e-02 GO:0000267 cell fraction
2.13 3.44e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
30.22 2.00e-02 GO:0001968 fibronectin binding
28.06 2.53e-02 GO:0043394 proteoglycan binding
18.71 9.71e-03 GO:0005158 insulin receptor binding
16.90 1.47e-02 GO:0016504 peptidase activator activity
11.46 4.23e-04 GO:0005201 extracellular matrix structural constituent
5.41 2.00e-02 GO:0010843 promoter binding
5.19 2.64e-02 GO:0000975 regulatory region DNA binding
5.19 2.64e-02 GO:0001067 regulatory region nucleic acid binding
5.19 2.64e-02 GO:0044212 transcription regulatory region DNA binding
4.52 2.91e-02 GO:0032403 protein complex binding
3.06 1.84e-02 GO:0043565 sequence-specific DNA binding
3.03 4.42e-04 GO:0030528 transcription regulator activity
2.69 1.24e-02 GO:0001071 nucleic acid binding transcription factor activity
2.69 1.24e-02 GO:0003700 sequence-specific DNA binding transcription factor activity