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Motif ID: RXRG_dimer.p3

Z-value: 1.718

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_+_116700620	14.878	NM_000040	APOC3	apolipoprotein C-III
chr20_+_56136136	9.758	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr11_-_116708334	8.788	NM_000039	APOA1	apolipoprotein A-I
chr3_+_46539484	7.767	NM_031440	RTP3	receptor (chemosensory) transporter protein 3
chr4_-_72671236	7.186	NM_001204306	GC	group-specific component (vitamin D binding protein)
chr1_-_173886464	6.734	NM_000488	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_+_31623688	6.290		APOM	apolipoprotein M
chr19_+_45116921	6.080	NM_001205280	IGSF23	immunoglobulin superfamily, member 23
chr1_-_120311466	5.921	NM_001166107 NM_005518	HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr2_+_219283809	5.638	NM_007127	VIL1	villin 1
chr6_+_31623668	5.633	NM_019101	APOM	apolipoprotein M
chr1_+_145727712	5.449		PDZK1	PDZ domain containing 1
chr10_-_96829074	5.314	NM_000770 NM_001198853 NM_001198854 NM_001198855	CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8
chr9_+_74764266	5.292	NM_001242505 NM_001242506 NM_004293	GDA	guanine deaminase
chr1_+_145727665	5.249	NM_001201325 NM_001201326 NM_002614	PDZK1	PDZ domain containing 1
chr9_+_74764394	4.537		GDA	guanine deaminase
chr10_-_52645430	4.502	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr10_+_102732285	4.414	NM_001203244 NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr12_+_56624500	4.398	NM_001135195	SLC39A5	solute carrier family 39 (metal ion transporter), member 5
chr3_-_48936227	4.263	NM_000387	SLC25A20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr1_-_173886401	4.144		SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr9_+_74764382	3.816		GDA	guanine deaminase
chr1_-_15911461	3.366	NM_024758	AGMAT	agmatine ureohydrolase (agmatinase)
chr10_-_52645384	3.256		A1CF	APOBEC1 complementation factor
chr17_+_7533452	3.134	NM_001040 NM_001146279 NM_001146280 NM_001146281	SHBG	sex hormone-binding globulin
chr20_+_42187705	3.093		SGK2	serum/glucocorticoid regulated kinase 2
chr13_+_100741268	3.022	NM_000282 NM_001127692 NM_001178004	PCCA	propionyl CoA carboxylase, alpha polypeptide
chr17_+_7533403	2.930		SHBG	sex hormone-binding globulin
chr9_+_74764354	2.869		GDA	guanine deaminase
chr20_+_36661849	2.837	NM_021215	RPRD1B	regulation of nuclear pre-mRNA domain containing 1B
chr9_+_74764417	2.568		GDA	guanine deaminase
chr9_-_27005649	2.549	NM_022901	LRRC19	leucine rich repeat containing 19
chr9_+_115142395	2.537		HSDL2	hydroxysteroid dehydrogenase like 2
chr2_-_28113211	2.537	NM_022128	RBKS	ribokinase
chr6_+_143771779	2.531	NM_003630	PEX3	peroxisomal biogenesis factor 3
chr9_+_115142188	2.508	NM_001195822 NM_032303	HSDL2	hydroxysteroid dehydrogenase like 2
chr2_-_207024103	2.505	NM_001199981 NM_001199982 NM_001199983 NM_005006	NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr20_+_36662138	2.480		RPRD1B	regulation of nuclear pre-mRNA domain containing 1B
chr17_-_2614926	2.409	NM_015229	KIAA0664	KIAA0664
chr17_-_36104874	2.329		HNF1B	HNF1 homeobox B
chr1_+_61547625	2.323	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr12_+_121416294	2.299		HNF1A	HNF1 homeobox A
chrX_+_111326252	2.263	NM_001004308	ZCCHC16	zinc finger, CCHC domain containing 16
chr8_-_80942488	2.231	NM_014018	MRPS28	mitochondrial ribosomal protein S28
chr17_-_36105005	2.216	NM_000458 NM_001165923	HNF1B	HNF1 homeobox B
chr1_+_196857143	2.204	NM_001201550 NM_001201551 NM_006684	CFHR4	complement factor H-related 4
chr7_+_137761177	1.913	NM_001190906 NM_001190907 NM_005989	AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
chr10_-_21814610	1.827	NM_207371	C10orf140	chromosome 10 open reading frame 140
chr8_-_144815888	1.789	NM_198488	FAM83H	family with sequence similarity 83, member H
chr16_-_87970107	1.788	NM_001739	CA5A	carbonic anhydrase VA, mitochondrial
chr17_+_7123246	1.778		ACADVL	acyl-CoA dehydrogenase, very long chain
chr12_-_7125727	1.747	NM_005768	LPCAT3	lysophosphatidylcholine acyltransferase 3
chr7_-_74489572	1.666		WBSCR16	Williams-Beuren syndrome chromosome region 16
chr1_-_55089068	1.663	NM_176782	FAM151A	family with sequence similarity 151, member A
chr1_-_217250230	1.650	NM_001243507 NM_001243509	ESRRG	estrogen-related receptor gamma
chr4_+_140587086	1.634		MGST2	microsomal glutathione S-transferase 2
chr2_+_120125141	1.611	NM_001079863	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr7_-_100844192	1.587	NM_178176	MOGAT3	monoacylglycerol O-acyltransferase 3
chr20_+_36662207	1.547
chr2_-_176046120	1.538	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr1_+_101491401	1.538
chr19_+_10362912	1.522		MRPL4	mitochondrial ribosomal protein L4
chr3_-_113464640	1.459		NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_178257371	1.458	NM_003659	AGPS	alkylglycerone phosphate synthase
chr8_-_124286489	1.450		ZHX1	zinc fingers and homeoboxes 1
chrX_+_106171328	1.449		CLDN2	claudin 2
chr1_-_6761839	1.429		DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr1_-_6761878	1.397		DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr7_-_143105897	1.381	NM_005232	EPHA1	EPH receptor A1
chr7_-_74489686	1.368	NM_030798	WBSCR16	Williams-Beuren syndrome chromosome region 16
chrX_+_105937067	1.337	NM_024539	RNF128	ring finger protein 128
chr2_+_178257488	1.287		AGPS	alkylglycerone phosphate synthase
chr1_-_95538443	1.246	NM_144988	ALG14	asparagine-linked glycosylation 14 homolog (S. cerevisiae)
chr6_+_33172418	1.239	NM_014234	HSD17B8	hydroxysteroid (17-beta) dehydrogenase 8
chr7_-_74489636	1.207		WBSCR16	Williams-Beuren syndrome chromosome region 16
chr12_+_121416548	1.175	NM_000545	HNF1A	HNF1 homeobox A
chr19_+_50016490	1.174		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr1_-_101491308	1.163	NM_001077394 NM_001077395 NM_015958	DPH5	DPH5 homolog (S. cerevisiae)
chr19_+_10196972	1.149		C19orf66	chromosome 19 open reading frame 66
chr4_-_4543690	1.140		STX18	syntaxin 18
chr20_+_42187634	1.123	NM_170693	SGK2	serum/glucocorticoid regulated kinase 2
chr18_+_54318561	1.114	NM_015285 NM_052834	WDR7	WD repeat domain 7
chr20_+_44509847	1.113	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr5_+_132209354	1.104	NM_052971	LEAP2	liver expressed antimicrobial peptide 2
chr18_+_29598444	1.086	NM_017831	RNF125	ring finger protein 125
chr14_+_50087400	1.081	NM_002408	MGAT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr2_+_219646448	1.079	NM_000784	CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1
chr19_+_10362886	1.046		MRPL4	mitochondrial ribosomal protein L4
chr5_+_42548314	1.028	NM_001242403	GHR	growth hormone receptor
chr20_-_32899607	1.020	NM_001161766	AHCY	adenosylhomocysteinase
chr12_-_7079616	1.013		PHB2	prohibitin 2
chr4_-_7069755	1.005	NM_025196	GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr19_+_16308664	0.991	NM_001130524 NM_032493	AP1M1	adaptor-related protein complex 1, mu 1 subunit
chr16_+_4714709	0.977		MGRN1	mahogunin, ring finger 1
chrX_+_106143393	0.968	NM_001171092	CLDN2	claudin 2
chr19_-_55580896	0.967	NM_138412	RDH13	retinol dehydrogenase 13 (all-trans/9-cis)
chr1_-_6761897	0.927	NM_018198	DNAJC11	DnaJ (Hsp40) homolog, subfamily C, member 11
chr18_-_47340208	0.926	NM_006111	ACAA2	acetyl-CoA acyltransferase 2
chr22_+_25003610	0.924	NM_001032365	GGT1	gamma-glutamyltransferase 1
chr6_+_142468382	0.914		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr14_-_75643309	0.909		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr14_-_75643286	0.908		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr2_+_138721807	0.902	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr19_+_50016435	0.901	NM_004107	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr8_-_82607206	0.897	NM_001010893	SLC10A5	solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr14_-_75643333	0.894		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr16_+_4475804	0.884	NM_001135110 NM_005147	DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3
chr2_-_198364997	0.880	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr19_+_10197023	0.862		C19orf66	chromosome 19 open reading frame 66
chr1_-_151138330	0.860	NM_212551 NM_001136543	LYSMD1	LysM, putative peptidoglycan-binding, domain containing 1
chr20_-_20033005	0.846		CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr18_-_47339854	0.839		ACAA2	acetyl-CoA acyltransferase 2
chr11_-_45939361	0.821		PEX16	peroxisomal biogenesis factor 16
chr6_+_142468415	0.813		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr10_-_129691047	0.796
chr7_+_97841565	0.778	NM_177455	BHLHA15	basic helix-loop-helix family, member a15
chr10_+_695887	0.764		C10orf108	chromosome 10 open reading frame 108
chr7_-_65447187	0.751		GUSB	glucuronidase, beta
chr18_+_29598787	0.751		RNF125	ring finger protein 125
chr12_+_50135953	0.750		TMBIM6	transmembrane BAX inhibitor motif containing 6
chr6_+_142468401	0.732	NM_016485	VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr14_-_75643335	0.730	NM_006827	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr19_+_50016500	0.719		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr7_+_100318422	0.708	NM_000799	EPO	erythropoietin
chr22_+_30163351	0.703	NM_001003684 NM_013387	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X
chr1_-_40042461	0.699		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr5_+_14664803	0.695		FAM105B	family with sequence similarity 105, member B
chr22_+_41865112	0.685	NM_001098	ACO2	aconitase 2, mitochondrial
chr3_+_31574119	0.670		STT3B	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr14_-_95623665	0.667	NM_177438	DICER1	dicer 1, ribonuclease type III
chr19_-_51017124	0.662	NM_001114598	ASPDH	aspartate dehydrogenase domain containing
chr4_+_159593233	0.659	NM_004453	ETFDH	electron-transferring-flavoprotein dehydrogenase
chr4_-_7069801	0.637		GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr12_-_51422012	0.636	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_45097669	0.620		RNF220	ring finger protein 220
chr5_+_1801493	0.601	NM_004553	NDUFS6	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr8_-_124286566	0.598	NM_001204180 NM_001017926 NM_007222	ZHX1-C8ORF76 ZHX1	ZHX1-C8ORF76 readthrough zinc fingers and homeoboxes 1
chr1_-_40042519	0.592	NM_001135653 NM_001135654 NM_003819	PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr12_+_96252770	0.591		SNRPF	small nuclear ribonucleoprotein polypeptide F
chr17_+_7123149	0.589	NM_000018 NM_001033859	ACADVL	acyl-CoA dehydrogenase, very long chain
chr12_+_67663364	0.583		CAND1	cullin-associated and neddylation-dissociated 1
chr7_-_65447233	0.581	NM_000181	GUSB	glucuronidase, beta
chr17_+_26800657	0.573	NM_001145975 NM_001145976 NM_003984	SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr7_-_72936447	0.570		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr12_+_107168336	0.557	NM_018157	RIC8B	resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr12_+_69202796	0.538		MDM2	Mdm2 p53 binding protein homolog (mouse)
chr4_-_4543719	0.528		STX18	syntaxin 18
chr17_+_7531275	0.520		SHBG	sex hormone-binding globulin
chr16_-_4401265	0.516	NM_016069	PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr2_+_28113612	0.510		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr2_-_198364522	0.508		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr12_+_14538232	0.506		ATF7IP	activating transcription factor 7 interacting protein
chr11_+_86748870	0.504	NM_001168724 NM_022918	TMEM135	transmembrane protein 135
chrX_-_18372777	0.499	NM_006089	SCML2	sex comb on midleg-like 2 (Drosophila)
chr1_+_78354199	0.496	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr8_+_96037186	0.496	NM_152416	C8orf38	chromosome 8 open reading frame 38
chr19_+_50016606	0.495		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr7_-_72936592	0.488	NM_032408	BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr7_-_65447206	0.481		GUSB	glucuronidase, beta
chr7_-_139763520	0.477	NM_022750	PARP12	poly (ADP-ribose) polymerase family, member 12
chr12_+_67663147	0.471		CAND1	cullin-associated and neddylation-dissociated 1
chr5_+_14664764	0.456	NM_138348	FAM105B	family with sequence similarity 105, member B
chr1_+_45274153	0.441	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr11_+_118230348	0.429		UBE4A	ubiquitination factor E4A
chr2_-_220034706	0.424	NM_001144889 NM_001144890 NM_144712	SLC23A3	solute carrier family 23 (nucleobase transporters), member 3
chr9_-_116138340	0.418	NM_031219	HDHD3	haloacid dehalogenase-like hydrolase domain containing 3
chr6_+_96025343	0.411	NM_024641	MANEA	mannosidase, endo-alpha
chr14_-_21566497	0.411		ZNF219	zinc finger protein 219
chr7_-_65447162	0.410		GUSB	glucuronidase, beta
chr7_-_25164902	0.399	NM_018947	CYCS	cytochrome c, somatic
chr19_+_44100734	0.399	NM_001145347	ZNF576	zinc finger protein 576
chr1_-_120484230	0.398		NOTCH2	notch 2
chr1_-_160313029	0.398		COPA	coatomer protein complex, subunit alpha
chr1_-_160312959	0.393
chr22_-_44893436	0.393		LDOC1L	leucine zipper, down-regulated in cancer 1-like
chr7_-_25164869	0.391		CYCS	cytochrome c, somatic
chr2_-_159312955	0.387	NM_001171637 NM_138803	CCDC148	coiled-coil domain containing 148
chr12_-_118810550	0.384		TAOK3	TAO kinase 3
chr11_+_118230320	0.381		UBE4A	ubiquitination factor E4A
chr20_-_36661822	0.367	NM_014657	TTI1	TELO2 interacting protein 1
chr4_-_83931861	0.362		LIN54	lin-54 homolog (C. elegans)
chr15_-_82554990	0.359		EFTUD1	elongation factor Tu GTP binding domain containing 1
chr12_+_96252705	0.358	NM_003095	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr6_+_7108184	0.358		RREB1	ras responsive element binding protein 1
chrX_-_64254592	0.355	NM_001178032 NM_001243804	ZC4H2	zinc finger, C4H2 domain containing
chr2_+_73441344	0.355	NM_006062	SMYD5	SMYD family member 5
chr20_+_44486219	0.355	NM_080752	ZSWIM3	zinc finger, SWIM-type containing 3
chr11_-_73720281	0.353	NM_003356 NM_022803	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)
chr20_+_54967572	0.351	NM_001324	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr4_-_83931973	0.349	NM_001115008 NM_194282	LIN54	lin-54 homolog (C. elegans)
chr1_-_40042415	0.342		PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr16_-_30546145	0.339	NM_023931	ZNF747	zinc finger protein 747
chr22_-_44893179	0.338		LDOC1L	leucine zipper, down-regulated in cancer 1-like
chr2_+_198365012	0.337		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr22_+_38201113	0.330	NM_005318	H1F0	H1 histone family, member 0
chr11_+_117049387	0.328		SIDT2	SID1 transmembrane family, member 2
chr19_-_41812991	0.328
chr2_+_26568991	0.328		EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr2_+_28113481	0.317	NM_199193 NM_199194 NM_004899 NM_199191 NM_199192	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr11_+_117049838	0.314	NM_001040455	SIDT2	SID1 transmembrane family, member 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
8.36	2.71e-05	GO:0008610	lipid biosynthetic process
4.92	3.36e-05	GO:0006629	lipid metabolic process
8.99	5.81e-05	GO:0032787	monocarboxylic acid metabolic process
5.74	1.20e-04	GO:0044255	cellular lipid metabolic process
62.10	1.82e-04	GO:0043691	reverse cholesterol transport
3.26	4.72e-04	GO:0044281	small molecule metabolic process
17.04	5.71e-04	GO:0008203	cholesterol metabolic process
16.17	7.78e-04	GO:0006694	steroid biosynthetic process
15.85	8.76e-04	GO:0016125	sterol metabolic process
65.98	4.76e-03	GO:0034377	plasma lipoprotein particle assembly
65.98	4.76e-03	GO:0065005	protein-lipid complex assembly
8.94	5.33e-03	GO:0006631	fatty acid metabolic process
26.40	6.56e-03	GO:0030301	cholesterol transport
25.76	7.24e-03	GO:0015918	sterol transport
8.45	7.68e-03	GO:0008202	steroid metabolic process
10.86	7.79e-03	GO:0006869	lipid transport
56.56	7.84e-03	GO:0034375	high-density lipoprotein particle remodeling
4.54	1.05e-02	GO:0006082	organic acid metabolic process
5.68	1.10e-02	GO:0006066	alcohol metabolic process
9.97	1.26e-02	GO:0010876	lipid localization
175.92	1.82e-02	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
41.68	2.06e-02	GO:0034381	plasma lipoprotein particle clearance
39.59	2.42e-02	GO:0006699	bile acid biosynthetic process
37.71	2.81e-02	GO:0033344	cholesterol efflux
8.48	3.12e-02	GO:0010817	regulation of hormone levels
36.00	3.25e-02	GO:0034367	macromolecular complex remodeling
36.00	3.25e-02	GO:0034368	protein-lipid complex remodeling
36.00	3.25e-02	GO:0034369	plasma lipoprotein particle remodeling
131.95	3.64e-02	GO:0032488	Cdc42 protein signal transduction
4.22	4.66e-02	GO:0019752	carboxylic acid metabolic process
4.22	4.66e-02	GO:0043436	oxoacid metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
98.96	2.32e-04	GO:0034366	spherical high-density lipoprotein particle
3.41	8.11e-04	GO:0005739	mitochondrion
4.58	1.82e-03	GO:0044429	mitochondrial part
7.40	3.39e-03	GO:0005759	mitochondrial matrix
39.59	4.57e-03	GO:0034361	very-low-density lipoprotein particle
39.59	4.57e-03	GO:0034385	triglyceride-rich lipoprotein particle
33.00	8.02e-03	GO:0034364	high-density lipoprotein particle
6.21	1.02e-02	GO:0005743	mitochondrial inner membrane
5.70	1.74e-02	GO:0019866	organelle inner membrane
4.81	1.91e-02	GO:0005740	mitochondrial envelope
22.63	2.52e-02	GO:0032994	protein-lipid complex
22.63	2.52e-02	GO:0034358	plasma lipoprotein particle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
20.31	4.55e-04	GO:0005496	steroid binding
5.71	2.48e-03	GO:0008289	lipid binding
175.92	4.28e-03	GO:0070653	high-density lipoprotein particle receptor binding
30.46	1.27e-02	GO:0032934	sterol binding