Motif ID: SMAD1..7,9.p2

Z-value: 1.165


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMAD9hg19_v1_chr13_-_37494370_374944080.476.5e-03Click!
SMAD6hg19_v1_chr15_+_67000929_670009290.421.5e-02Click!
SMAD1hg19_v1_chr4_+_146403955_1464039620.402.3e-02Click!
SMAD4hg19_v1_chr18_+_48556483_485565860.355.0e-02Click!
SMAD7hg19_v1_chr18_-_46475702_46475702-0.115.6e-01Click!
SMAD5hg19_v1_chr5_+_135468522_1354685370.086.7e-01Click!
SMAD2hg19_v1_chr18_-_45457454_45457524-0.077.0e-01Click!
SMAD3hg19_v1_chr15_+_67458492_674585000.048.2e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_45826131 4.487 CKM
creatine kinase, muscle
chr19_-_45826232 3.535 NM_001824
 CKM
creatine kinase, muscle
chr5_-_146833150 2.562 NM_001387
 DPYSL3
dihydropyrimidinase-like 3
chr1_-_16345284 2.506 NM_014424
 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr2_-_97509733 2.375 NM_144994
 ANKRD23
ankyrin repeat domain 23
chr3_+_35681008 2.288 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr22_-_24640850 2.107 NM_001099781
NM_001099782
NM_004121
 GGT5


gamma-glutamyltransferase 5


chr2_+_220283098 2.006 NM_001927
 DES
desmin
chr11_-_2018885 2.001 H19
RPS12
H19, imprinted maternally expressed transcript (non-protein coding)
ribosomal protein S12
chr12_+_53443834 1.998 NM_170754
 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr11_+_66824308 1.981 RHOD
ras homolog gene family, member D
chr10_+_88428263 1.853 NM_001080116
NM_001080114
NM_001080115
NM_001171611
NM_007078
 LDB3




LIM domain binding 3




chr15_-_42448769 1.762 NM_213600
 PLA2G4F
phospholipase A2, group IVF
chr3_-_195306274 1.742 APOD
apolipoprotein D
chr11_-_2019007 1.740 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr11_+_47608229 1.691 NM_001164379
 FAM180B
family with sequence similarity 180, member B
chr17_-_37353731 1.670 NM_000723
NM_199247
NM_199248
 CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chr1_+_110009099 1.654 NM_001040709
 SYPL2
synaptophysin-like 2
chr2_+_233404436 1.606 NM_005199
 CHRNG
cholinergic receptor, nicotinic, gamma
chr20_+_30598244 1.575 NM_080625
 C20orf160
chromosome 20 open reading frame 160

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
52.47 8.08e-03 GO:0030239 myofibril assembly
40.81 1.76e-02 GO:0031032 actomyosin structure organization
29.99 3.05e-03 GO:0055002 striated muscle cell development
26.72 4.86e-03 GO:0055001 muscle cell development
18.85 1.94e-02 GO:0051146 striated muscle cell differentiation
14.59 7.39e-03 GO:0042692 muscle cell differentiation
10.69 3.27e-02 GO:0003012 muscle system process
8.53 2.19e-02 GO:0061061 muscle structure development

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
30.61 7.27e-04 GO:0031674 I band
26.24 6.38e-07 GO:0030017 sarcomere
22.76 1.73e-06 GO:0044449 contractile fiber part
22.17 2.07e-06 GO:0030016 myofibril
20.91 3.12e-06 GO:0043292 contractile fiber

Nothing significant found in function category.