Motif ID: SNAI1..3.p2

Z-value: 4.615


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SNAI3hg19_v1_chr16_-_88752788_88752875-0.291.1e-01Click!
SNAI1hg19_v1_chr20_+_48599511_485995960.232.0e-01Click!
SNAI2hg19_v1_chr8_-_49833823_498339980.057.9e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_7165788 24.977 CLDN7
claudin 7
chr19_+_6464259 23.859 NM_139161
NM_174881
 CRB3

crumbs homolog 3 (Drosophila)

chr9_-_97401588 23.793 FBP1
fructose-1,6-bisphosphatase 1
chr17_-_7166263 21.700 NM_001185023
NM_001307
 CLDN7

claudin 7

chr2_-_166650546 19.155 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr9_-_97401746 18.628 FBP1
fructose-1,6-bisphosphatase 1
chr1_+_151483861 18.319 NM_020770
 CGN
cingulin
chr2_-_166650770 18.312 NM_004482
 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr9_-_97401833 16.969 NM_000507
 FBP1
fructose-1,6-bisphosphatase 1
chr19_-_10697907 16.741 NM_005498
 AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_38755238 15.729 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr8_+_120220554 15.347 NM_052886
 MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr15_+_50474357 15.345 NM_001159629
NM_003645
 SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr1_+_60280462 15.242 NM_015888
 HOOK1
hook homolog 1 (Drosophila)
chr16_+_68771214 14.945 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr16_+_68771192 14.187 NM_004360
 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr20_+_44098392 13.967 NM_006103
 WFDC2
WAP four-disulfide core domain 2
chr19_+_38755097 13.907 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr17_-_46035109 13.585 NM_024320
 PRR15L
proline rich 15-like
chr7_-_73184535 13.441 NM_001306
 CLDN3
claudin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
9.99 2.69e-02 GO:0060428 lung epithelium development
2.34 9.59e-04 GO:0016477 cell migration
2.18 4.56e-03 GO:0048870 cell motility
2.18 4.56e-03 GO:0051674 localization of cell
2.03 8.14e-03 GO:0006928 cellular component movement
1.92 2.51e-04 GO:0006811 ion transport
1.90 6.90e-04 GO:0009888 tissue development
1.90 3.07e-02 GO:0048878 chemical homeostasis
1.85 4.61e-03 GO:0055085 transmembrane transport
1.84 2.83e-03 GO:0040011 locomotion
1.57 1.29e-02 GO:0009653 anatomical structure morphogenesis
1.51 6.17e-04 GO:0042221 response to chemical stimulus
1.43 3.68e-02 GO:0065008 regulation of biological quality
1.35 5.88e-03 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
5.04 5.35e-07 GO:0043296 apical junction complex
4.87 1.02e-06 GO:0016327 apicolateral plasma membrane
4.84 1.65e-05 GO:0005923 tight junction
4.84 1.65e-05 GO:0070160 occluding junction
4.51 1.47e-11 GO:0016324 apical plasma membrane
4.11 6.36e-12 GO:0045177 apical part of cell
3.43 6.26e-07 GO:0005911 cell-cell junction
2.90 2.52e-02 GO:0031253 cell projection membrane
1.81 1.06e-03 GO:0005624 membrane fraction
1.78 1.54e-03 GO:0005626 insoluble fraction
1.73 2.17e-04 GO:0000267 cell fraction
1.72 5.11e-10 GO:0044459 plasma membrane part
1.51 2.40e-04 GO:0005576 extracellular region
1.45 5.62e-09 GO:0071944 cell periphery
1.44 2.92e-08 GO:0005886 plasma membrane
1.36 9.70e-11 GO:0044425 membrane part
1.33 4.75e-13 GO:0016020 membrane
1.30 1.22e-05 GO:0031224 intrinsic to membrane
1.30 1.97e-05 GO:0016021 integral to membrane

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
17.32 1.07e-02 GO:0015205 nucleobase transmembrane transporter activity
14.43 3.09e-02 GO:0003840 gamma-glutamyltransferase activity
5.96 6.48e-04 GO:0003823 antigen binding
4.33 3.53e-03 GO:0005496 steroid binding
4.11 2.98e-02 GO:0015300 solute:solute antiporter activity
3.83 1.37e-05 GO:0015293 symporter activity
3.53 1.87e-02 GO:0015294 solute:cation symporter activity
3.52 2.63e-07 GO:0015291 secondary active transmembrane transporter activity
2.68 3.36e-06 GO:0022804 active transmembrane transporter activity
1.93 2.22e-04 GO:0015075 ion transmembrane transporter activity
1.89 7.35e-05 GO:0022891 substrate-specific transmembrane transporter activity
1.88 3.80e-05 GO:0022857 transmembrane transporter activity
1.72 1.47e-03 GO:0022892 substrate-specific transporter activity
1.70 3.90e-02 GO:0042802 identical protein binding
1.66 1.10e-03 GO:0005215 transporter activity