Motif ID: SOX{8,9,10}.p2

Z-value: 1.093


Transcription factors associated with SOX{8,9,10}.p2:

Gene SymbolEntrez IDGene Name
SOX10 6663 SRY (sex determining region Y)-box 10
SOX8 30812 SRY (sex determining region Y)-box 8
SOX9 6662 SRY (sex determining region Y)-box 9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX9hg19_v1_chr17_+_70117154_701171640.431.5e-02Click!
SOX8hg19_v1_chr16_+_1032063_10320850.173.4e-01Click!
SOX10hg19_v1_chr22_-_38380538_383805690.173.6e-01Click!


Activity profile for motif SOX{8,9,10}.p2.

activity profile for motif SOX{8,9,10}.p2


Sorted Z-values histogram for motif SOX{8,9,10}.p2

Sorted Z-values for motif SOX{8,9,10}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX{8,9,10}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_46904879 4.632 NM_000258
 MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_+_156589085 3.228 NM_021817
 HAPLN2
hyaluronan and proteoglycan link protein 2
chr2_-_158182154 2.879 NM_020711
 ERMN
ermin, ERM-like protein
chr3_-_185826748 2.490 NM_004454
 ETV5
ets variant 5
chr19_-_49658645 2.417 NM_002152
 HRC
histidine rich calcium binding protein
chr6_-_46293215 2.341 RCAN2
regulator of calcineurin 2
chrX_+_49126326 2.148 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr1_-_205912546 2.090 NM_052934
NM_134325
 SLC26A9

solute carrier family 26, member 9

chr6_-_46293404 1.925 RCAN2
regulator of calcineurin 2
chr14_-_102975996 1.871 ANKRD9
ankyrin repeat domain 9
chr8_-_70745403 1.849 NM_001146009
 SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_-_15130773 1.723 NM_001039844
 ACBD7
acyl-CoA binding domain containing 7
chr4_-_186732047 1.706 NM_001145672
 SORBS2
sorbin and SH3 domain containing 2
chr11_-_35440514 1.697 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_139613114 1.671 NM_153235
 TXLNB
taxilin beta
chr14_-_102976096 1.645 NM_152326
 ANKRD9
ankyrin repeat domain 9
chr10_-_97321094 1.590 NM_015385
NM_024991
 SORBS1

sorbin and SH3 domain containing 1

chr4_+_41614911 1.556 NM_001112719
NM_001112720
 LIMCH1

LIM and calponin homology domains 1

chr8_+_144295067 1.514 NM_178172
 GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr5_-_83680191 1.504 EDIL3
EGF-like repeats and discoidin I-like domains 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
2.47 1.04e-03 GO:0048731 system development
2.30 2.54e-03 GO:0048856 anatomical structure development
2.25 1.46e-03 GO:0007275 multicellular organismal development
2.12 3.38e-03 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
19.29 4.79e-03 GO:0031674 I band

Nothing significant found in function category.