Motif ID: SP1.p2

Z-value: 1.914


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SP1hg19_v1_chr12_+_53774422_53774427-0.241.9e-01Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_114018365 5.357 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr15_+_80445177 4.629 NM_000137
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr14_+_104552015 4.122 NM_001080464
ASPG
asparaginase homolog (S. cerevisiae)
chr15_+_80445340 4.049 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr13_-_114018201 3.767 GRTP1
growth hormone regulated TBC protein 1
chr15_+_80445129 3.665 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr9_+_139685816 3.553


chr1_+_955609 3.461 AGRN
agrin
chr22_-_50746000 3.355 NM_012401
PLXNB2
plexin B2
chr21_+_45875368 3.293 NM_030891
LRRC3
leucine rich repeat containing 3
chr10_-_135171512 2.951 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr3_-_128840605 2.906 NM_001204886
NM_001204887
NM_001204888
NM_198490
NM_001204885
RAB43




RAB43, member RAS oncogene family




chr1_+_955468 2.866 NM_198576
AGRN
agrin
chr4_+_1005609 2.720 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr6_-_18155283 2.621 NM_000367
TPMT
thiopurine S-methyltransferase
chr21_-_44496423 2.605 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr21_-_44495894 2.596 NM_000071
CBS
cystathionine-beta-synthase
chr19_-_50832633 2.503 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr8_-_144815888 2.462 NM_198488
FAM83H
family with sequence similarity 83, member H
chr21_+_44073650 2.452 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A




















Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
16.92 8.59e-03 GO:0046626 regulation of insulin receptor signaling pathway
3.10 2.61e-03 GO:0009725 response to hormone stimulus
2.83 1.14e-02 GO:0009719 response to endogenous stimulus

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
8.15 2.70e-04 GO:0043296 apical junction complex
7.87 3.61e-04 GO:0016327 apicolateral plasma membrane
7.17 9.23e-03 GO:0005923 tight junction
7.17 9.23e-03 GO:0070160 occluding junction
3.98 3.91e-02 GO:0005911 cell-cell junction

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
13.90 6.45e-03 GO:0005158 insulin receptor binding