Motif ID: SRF.p3

Z-value: 4.472


Transcription factors associated with SRF.p3:

Gene SymbolEntrez IDGene Name
SRF 6722 serum response factor (c-fos serum response element-binding transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SRFhg19_v1_chr6_+_43139190_431391960.803.2e-08Click!


Activity profile for motif SRF.p3.

activity profile for motif SRF.p3


Sorted Z-values histogram for motif SRF.p3

Sorted Z-values for motif SRF.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_45826131 74.254 CKM
creatine kinase, muscle
chr19_-_45826232 46.446 NM_001824
CKM
creatine kinase, muscle
chr2_+_74120132 43.077 ACTG2
actin, gamma 2, smooth muscle, enteric
chr15_-_35087748 42.367 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr1_-_229569839 40.271 NM_001100
ACTA1
actin, alpha 1, skeletal muscle
chr2_+_74120092 39.327 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr20_+_35169876 32.651 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr14_-_94443065 29.473 NM_001202429
ASB2
ankyrin repeat and SOCS box containing 2
chr19_-_36247917 29.096 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr10_-_29923841 27.795


chr20_+_35169897 27.484 MYL9
myosin, light chain 9, regulatory
chr6_-_123957941 23.050 NM_001251987
NM_006073
TRDN

triadin

chr14_-_23877480 22.250 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr17_+_33474835 21.367 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr14_-_94442894 21.043 ASB2
ankyrin repeat and SOCS box containing 2
chr8_+_86351055 20.480 NM_005181
CA3
carbonic anhydrase III, muscle specific
chr10_+_88428263 20.267 NM_001080116
NM_001080114
NM_001080115
NM_001171611
NM_007078
LDB3




LIM domain binding 3




chr10_-_29923900 18.805 NM_021738
SVIL
supervillin
chr3_-_151987332 18.608 LOC401093
uncharacterized LOC401093
chr6_-_105584982 18.518 NM_001199563
BVES
blood vessel epicardial substance
chr1_-_16344438 17.631 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr2_+_88367298 17.619 NM_198274
SMYD1
SET and MYND domain containing 1
chr1_-_208084379 16.589 CD34
CD34 molecule
chr1_-_208084432 16.379 NM_001025109
NM_001773
CD34

CD34 molecule

chr11_+_117070039 15.130 NM_001001522
NM_003186
TAGLN

transgelin

chr2_-_161056762 15.047 ITGB6
integrin, beta 6
chr22_+_31480981 14.925 NM_001207018
SMTN
smoothelin
chr20_-_42815732 14.831 JPH2
junctophilin 2
chr10_+_88428167 14.428 NM_001171610
LDB3
LIM domain binding 3
chr10_-_131762374 13.895 EBF3
early B-cell factor 3
chr3_-_46904879 13.010 NM_000258
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_-_242162364 12.910 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr12_+_52445185 12.802 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr11_+_66314373 12.675 NM_001104
ACTN3
actinin, alpha 3
chr3_-_99594915 12.562 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr1_+_16085245 12.368 NM_017556
FBLIM1
filamin binding LIM protein 1
chr4_-_88450601 11.999 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr18_-_3219846 11.029 MYOM1
myomesin 1, 185kDa
chr10_-_90712510 10.565 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr5_+_42565963 10.470 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr4_+_24797084 10.469 NM_003102
SOD3
superoxide dismutase 3, extracellular
chr2_-_128432642 10.216 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr7_-_27183225 9.958 NM_019102
HOXA5
homeobox A5
chr2_-_106015423 9.831 NM_001039492
NM_001450
NM_201555
FHL2


four and a half LIM domains 2


chr15_-_65360297 9.478 NM_016563
RASL12
RAS-like, family 12
chr14_-_53417808 9.453 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr19_+_13135368 9.231 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_13134782 9.033 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr15_+_96869156 8.781 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_-_20306093 8.667 NM_001161729
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr5_-_33891967 8.395 NM_030955
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr17_+_41003184 7.740 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr4_-_88450243 7.407 SPARCL1
SPARC-like 1 (hevin)
chr7_-_107643330 7.369 NM_002291
LAMB1
laminin, beta 1
chr17_-_1389323 7.178 MYO1C
myosin IC
chr6_+_151561094 7.103 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr15_+_96873845 7.032 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_+_42565562 6.688 NM_001242406
GHR
growth hormone receptor
chr3_+_187930720 6.430 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_154164551 6.347 NM_152263
TPM3
tropomyosin 3
chr7_+_20686965 6.298 NM_001163942
NM_001163993
NM_178559
ABCB5


ATP-binding cassette, sub-family B (MDR/TAP), member 5


chr16_-_11375094 5.759 NM_002761
PRM1
protamine 1
chr18_-_3219986 5.746 NM_003803
NM_019856
MYOM1

myomesin 1, 185kDa

chr12_+_26348488 5.670 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chrX_+_99839789 5.664 NM_022144
TNMD
tenomodulin
chrX_-_153602928 5.624 FLNA
filamin A, alpha
chr17_+_32612686 5.418 NM_002986
CCL11
chemokine (C-C motif) ligand 11
chr20_+_4702499 5.411 NM_012409
PRND
prion protein 2 (dublet)
chr17_-_79792867 5.202 PPP1R27
protein phosphatase 1, regulatory subunit 27
chr5_-_33892292 5.171 ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr7_+_114055048 5.052 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr11_-_65667809 5.009 FOSL1
FOS-like antigen 1
chr10_+_75757847 4.944 NM_003373
NM_014000
VCL

vinculin

chr6_+_151561508 4.920 AKAP12
A kinase (PRKA) anchor protein 12
chr17_-_10560625 4.707 NM_002470
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr2_-_161056573 4.655 NM_000888
ITGB6
integrin, beta 6
chr6_+_116832807 4.485 NM_153711
FAM26E
family with sequence similarity 26, member E
chr7_-_94285477 4.381 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr7_-_94285372 4.361 SGCE
sarcoglycan, epsilon
chr5_+_88185090 4.244


chr6_+_43138919 4.113 NM_003131
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr7_-_94285426 4.110 SGCE
sarcoglycan, epsilon
chr6_-_76203256 4.049 NM_015687
FILIP1
filamin A interacting protein 1
chr11_-_65667860 4.046 NM_005438
FOSL1
FOS-like antigen 1
chr12_+_2162703 3.984 CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chrX_-_11284094 3.977 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr6_+_43139190 3.944 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr12_-_91505541 3.878 NM_002345
LUM
lumican
chr20_+_61147659 3.864 NM_178463
C20orf166
chromosome 20 open reading frame 166
chr10_+_123922940 3.850 TACC2
transforming, acidic coiled-coil containing protein 2
chr10_+_31610063 3.829 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr9_-_79520878 3.769 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chrX_-_153602998 3.764 NM_001110556
NM_001456
FLNA

filamin A, alpha

chr10_-_45474210 3.695 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr11_-_19223516 3.668 NM_001127656
NM_003476
CSRP3

cysteine and glycine-rich protein 3 (cardiac LIM protein)

chr17_-_79792923 3.644 NM_001007533
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr7_+_134464161 3.612 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr11_-_75921785 3.492 WNT11
wingless-type MMTV integration site family, member 11
chr1_-_168106810 3.484 GPR161
G protein-coupled receptor 161
chr11_-_2162167 3.456 IGF2
insulin-like growth factor 2 (somatomedin A)
chr7_-_44180911 3.423 NM_021223
MYL7
myosin, light chain 7, regulatory
chr3_+_187871473 3.401 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_-_32430370 3.363 NM_004011
NM_004012
DMD

dystrophin

chr16_+_70657894 3.350 NM_001172772
IL34
interleukin 34
chr2_+_26915390 3.335 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr5_+_149546340 3.297 NM_001804
CDX1
caudal type homeobox 1
chr2_-_216248184 3.278 FN1
fibronectin 1
chr11_+_75273245 3.267 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr4_+_120056938 3.225 NM_016599
MYOZ2
myozenin 2
chr6_+_43139201 3.204 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr3_-_123339423 3.186 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr5_-_58295758 3.171 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_87928083 3.156 NM_005935
AFF1
AF4/FMR2 family, member 1
chr2_+_108602978 3.004 NM_021815
SLC5A7
solute carrier family 5 (choline transporter), member 7
chrX_-_45060081 2.985 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr17_-_46671043 2.969 NM_002147
HOXB5
homeobox B5
chr1_-_147245483 2.966 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr1_+_113263188 2.926 NM_001004440
NM_182759
FAM19A3

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

chr19_+_35849487 2.890 NM_005304
FFAR3
free fatty acid receptor 3
chr16_+_31483066 2.872 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr2_+_101179395 2.857 NM_024065
PDCL3
phosducin-like 3
chr14_+_63671101 2.830 NM_020663
RHOJ
ras homolog gene family, member J
chr4_+_87968191 2.801 AFF1
AF4/FMR2 family, member 1
chr15_+_33603162 2.791 NM_001036
NM_001243996
RYR3

ryanodine receptor 3

chr19_+_49376488 2.788 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr17_-_39684585 2.731 NM_002276
KRT19
keratin 19
chr6_-_29527477 2.716 UBD
ubiquitin D
chr2_-_151344145 2.699 NM_005168
RND3
Rho family GTPase 3
chrX_-_10851808 2.660 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr10_+_6186758 2.627 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_-_123065836 2.618 CLMP
CXADR-like membrane protein
chr12_-_50616425 2.593 NM_001113547
LIMA1
LIM domain and actin binding 1
chr15_+_45406518 2.564 NM_207581
DUOXA2
dual oxidase maturation factor 2
chr15_+_40643225 2.562 NM_001145643
PHGR1
proline/histidine/glycine-rich 1
chr19_+_16178170 2.481 NM_001145160
TPM4
tropomyosin 4
chr3_-_123339178 2.414 MYLK
myosin light chain kinase
chr20_-_62680880 2.391 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr1_-_31845818 2.343 NM_004102
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr20_+_207898 2.271 NM_080831
DEFB129
defensin, beta 129
chr7_+_115863004 2.248 NM_152829
TES
testis derived transcript (3 LIM domains)
chr6_-_29527701 2.233 NM_006398
UBD
ubiquitin D
chr16_+_30077120 2.222 ALDOA
aldolase A, fructose-bisphosphate
chr4_+_15376174 2.199 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr17_+_41003360 2.199


chr21_-_47704166 2.162 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr15_+_74218962 2.153 LOXL1
lysyl oxidase-like 1
chr19_-_46283763 2.151 NM_001081563
DMPK
dystrophia myotonica-protein kinase
chr20_+_33146500 2.141 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr16_+_30077146 2.127 ALDOA
aldolase A, fructose-bisphosphate
chr10_-_16859408 2.107 NM_012425
NM_152724
RSU1

Ras suppressor protein 1

chr19_-_42894419 2.088 NM_032488
CNFN
cornifelin
chr7_-_559479 2.054 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr5_-_169816637 2.012 NM_004137
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr10_-_16859389 1.993 RSU1
Ras suppressor protein 1
chr19_+_54372659 1.971 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr2_-_96810775 1.963 DUSP2
dual specificity phosphatase 2
chrX_+_70521627 1.942 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr16_+_30076993 1.928 NM_001243177
NM_184041
ALDOA

aldolase A, fructose-bisphosphate

chr8_-_22550708 1.910 NM_004430
EGR3
early growth response 3
chr9_+_139249251 1.906 NM_001200003
GPSM1
G-protein signaling modulator 1
chr17_-_1389013 1.902 NM_001080950
MYO1C
myosin IC
chr12_+_54426831 1.886 NM_018953
HOXC5
homeobox C5
chrX_-_153599719 1.884 FLNA
filamin A, alpha
chr15_-_45406345 1.796 NM_014080
DUOX2
dual oxidase 2
chr3_+_63953419 1.770 NM_001128149
ATXN7
ataxin 7
chr5_+_169816490 1.769


chr11_-_4718948 1.758 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr7_-_80548322 1.720 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_80548666 1.716 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_+_114055234 1.713 FOXP2
forkhead box P2
chr4_-_76957139 1.668 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr6_+_144612872 1.589 NM_007124
UTRN
utrophin
chr10_+_64280206 1.581 NM_199452
ZNF365
zinc finger protein 365
chr18_+_61144143 1.567 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_+_50497790 1.553 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr1_+_181057835 1.540 IER5
immediate early response 5
chr1_+_43148048 1.515 NM_004559
YBX1
Y box binding protein 1
chr17_-_10372875 1.505 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr17_-_41132019 1.497 NM_025267
AARSD1
alanyl-tRNA synthetase domain containing 1
chr17_-_73505914 1.494 NM_001142643
CASKIN2
CASK interacting protein 2
chr17_-_46671322 1.451 HOXB5
homeobox B5
chr7_+_114055171 1.450 FOXP2
forkhead box P2
chr19_+_1026582 1.435 CNN2
calponin 2
chr3_-_101405400 1.428 NM_000986
RPL24
ribosomal protein L24
chr13_-_78549663 1.415 NM_000115
EDNRB
endothelin receptor type B
chr6_-_29644930 1.409 NM_001109809
ZFP57
zinc finger protein 57 homolog (mouse)
chr5_-_124080773 1.391 NM_020747
ZNF608
zinc finger protein 608
chr10_+_6186903 1.376 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr4_+_186064416 1.372 NM_001151
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr11_-_65667858 1.353 FOSL1
FOS-like antigen 1
chr6_-_86388419 1.309 SNHG5
small nucleolar RNA host gene 5 (non-protein coding)
chr15_-_45406322 1.297 DUOX2
dual oxidase 2
chr1_-_935469 1.275 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr17_+_3379295 1.237 NM_000049
ASPA
aspartoacylase
chr1_-_89591685 1.208 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr22_+_38004676 1.205 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr10_+_6186878 1.182 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr22_+_38004865 1.159 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr20_+_61147924 1.144 C20orf166
chromosome 20 open reading frame 166
chr1_+_19970674 1.129 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
17.59 2.41e-22 GO:0006936 muscle contraction
16.16 2.38e-21 GO:0003012 muscle system process
11.04 6.66e-12 GO:0007517 muscle organ development
8.32 7.02e-11 GO:0030029 actin filament-based process
8.26 3.26e-10 GO:0061061 muscle structure development
28.89 8.47e-10 GO:0030049 muscle filament sliding
28.89 8.47e-10 GO:0033275 actin-myosin filament sliding
23.06 9.15e-10 GO:0030048 actin filament-based movement
28.13 1.14e-09 GO:0070252 actin-mediated cell contraction
1.86 1.44e-07 GO:0032501 multicellular organismal process
2.59 6.07e-06 GO:0048513 organ development
2.63 1.75e-05 GO:0003008 system process
2.01 2.66e-05 GO:0007275 multicellular organismal development
1.89 1.25e-04 GO:0032502 developmental process
2.01 1.51e-04 GO:0048856 anatomical structure development
2.06 2.30e-04 GO:0048731 system development
5.97 2.33e-04 GO:0030036 actin cytoskeleton organization
8.29 2.87e-04 GO:0060537 muscle tissue development
8.16 1.28e-03 GO:0014706 striated muscle tissue development
7.58 2.37e-03 GO:0034329 cell junction assembly
3.03 2.69e-03 GO:0009888 tissue development
19.80 3.60e-03 GO:0031032 actomyosin structure organization
9.85 5.47e-03 GO:0007015 actin filament organization
6.83 5.59e-03 GO:0034330 cell junction organization
4.62 9.55e-03 GO:0048729 tissue morphogenesis
10.69 1.57e-02 GO:0008360 regulation of cell shape
10.35 1.90e-02 GO:0007519 skeletal muscle tissue development
7.88 2.38e-02 GO:0003007 heart morphogenesis
7.80 2.55e-02 GO:0031589 cell-substrate adhesion
9.72 2.73e-02 GO:0060538 skeletal muscle organ development
20.36 3.05e-02 GO:0030239 myofibril assembly
9.44 3.24e-02 GO:0006937 regulation of muscle contraction
2.24 3.46e-02 GO:0009653 anatomical structure morphogenesis
4.80 3.76e-02 GO:0007507 heart development
2.85 4.98e-02 GO:0071844 cellular component assembly at cellular level

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
19.99 1.32e-21 GO:0043292 contractile fiber
20.28 9.45e-21 GO:0030016 myofibril
19.87 1.49e-19 GO:0044449 contractile fiber part
9.35 2.75e-15 GO:0015629 actin cytoskeleton
18.55 4.47e-15 GO:0030017 sarcomere
3.13 2.03e-09 GO:0005856 cytoskeleton
12.96 1.89e-08 GO:0005925 focal adhesion
12.34 3.40e-08 GO:0005924 cell-substrate adherens junction
11.88 5.31e-08 GO:0030055 cell-substrate junction
20.05 7.49e-08 GO:0031674 I band
25.92 7.81e-08 GO:0042641 actomyosin
26.73 7.69e-07 GO:0001725 stress fiber
24.94 1.30e-06 GO:0032432 actin filament bundle
8.61 2.17e-06 GO:0005912 adherens junction
7.78 6.80e-06 GO:0070161 anchoring junction
3.96 1.07e-05 GO:0030054 cell junction
13.37 1.95e-05 GO:0016459 myosin complex
29.70 7.28e-05 GO:0005859 muscle myosin complex
2.03 9.75e-05 GO:0043228 non-membrane-bounded organelle
2.03 9.75e-05 GO:0043232 intracellular non-membrane-bounded organelle
26.73 1.30e-04 GO:0016460 myosin II complex
16.88 1.83e-04 GO:0030018 Z disc
5.61 2.34e-04 GO:0016323 basolateral plasma membrane
35.63 4.80e-04 GO:0043034 costamere
32.89 6.88e-04 GO:0031672 A band
2.68 8.50e-04 GO:0044430 cytoskeletal part
15.72 2.10e-03 GO:0005884 actin filament
23.76 2.84e-03 GO:0032982 myosin filament
2.00 2.89e-03 GO:0044459 plasma membrane part
8.91 7.98e-03 GO:0042383 sarcolemma
2.44 1.39e-02 GO:0044421 extracellular region part
1.89 2.56e-02 GO:0005829 cytosol
24.67 2.99e-02 GO:0005865 striated muscle thin filament
1.30 4.44e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
27.35 2.72e-11 GO:0008307 structural constituent of muscle
6.13 1.61e-07 GO:0003779 actin binding
4.36 2.67e-06 GO:0008092 cytoskeletal protein binding
3.53 3.44e-04 GO:0005198 structural molecule activity
26.73 2.22e-03 GO:0000146 microfilament motor activity
3.59 7.09e-03 GO:0042803 protein homodimerization activity
17.11 1.44e-02 GO:0017022 myosin binding
1.19 4.20e-02 GO:0005488 binding
71.26 4.67e-02 GO:0002162 dystroglycan binding