Motif ID: SRY.p2

Z-value: 1.033


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SRYhg19_v1_chrY_-_2655478_2655791-0.241.8e-01Click!


Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_39509069 7.036 NM_182935
 MOBP
myelin-associated oligodendrocyte basic protein
chr18_+_29171729 6.108 NM_000371
 TTR
transthyretin
chr9_-_104198045 5.039 NM_000035
 ALDOB
aldolase B, fructose-bisphosphate
chr7_+_107110501 3.864 NM_005295
 GPR22
G protein-coupled receptor 22
chr11_-_35440514 3.343 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_-_65409445 2.902 NM_002083
 GPX2
glutathione peroxidase 2 (gastrointestinal)
chr4_-_176733413 2.608 GPM6A
glycoprotein M6A
chr5_-_39364562 2.486 NM_001737
 C9
complement component 9
chr12_-_21487831 2.410 NM_021094
 SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr2_-_21230572 2.392 APOB
apolipoprotein B (including Ag(x) antigen)
chr7_+_26400503 2.368 NM_001199837
 SNX10
sorting nexin 10
chr12_-_10151689 2.297 NM_001099431
NM_016509
 CLEC1B

C-type lectin domain family 1, member B

chr2_+_102927961 2.205 NM_016232
 IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr4_+_74269971 2.205 NM_000477
 ALB
albumin
chr9_+_77112251 2.185 NM_006914
 RORB
RAR-related orphan receptor B
chr1_-_193155723 2.149 NM_003783
 B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_+_135596185 2.097 NM_138326
 ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr2_-_158182154 2.062 NM_020711
 ERMN
ermin, ERM-like protein
chr5_+_173472737 2.034 HMP19
HMP19 protein
chr17_-_26697224 2.026 VTN
vitronectin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
154.94 2.27e-02 GO:0001907 killing by symbiont of host cells
154.94 2.27e-02 GO:0019836 hemolysis by symbiont of host erythrocytes
154.94 2.27e-02 GO:0044004 disruption by symbiont of host cells
154.94 2.27e-02 GO:0044179 hemolysis in other organism
154.94 2.27e-02 GO:0051715 cytolysis in other organism
154.94 2.27e-02 GO:0051801 cytolysis in other organism involved in symbiotic interaction
154.94 2.27e-02 GO:0052025 modification by symbiont of host cell membrane
154.94 2.27e-02 GO:0052043 modification by symbiont of host cellular component
154.94 2.27e-02 GO:0052111 modification by symbiont of host structure
154.94 2.27e-02 GO:0052185 modification of structure of other organism involved in symbiotic interaction
154.94 2.27e-02 GO:0052188 modification of cellular component in other organism involved in symbiotic interaction
154.94 2.27e-02 GO:0052331 hemolysis in other organism involved in symbiotic interaction
154.94 2.27e-02 GO:0052332 modification by organism of cell membrane in other organism involved in symbiotic interaction
5.67 4.51e-02 GO:0008202 steroid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
88.54 6.97e-06 GO:0005577 fibrinogen complex
23.25 3.43e-02 GO:0044304 main axon
14.91 2.54e-03 GO:0031983 vesicle lumen
13.19 2.92e-02 GO:0031093 platelet alpha granule lumen
12.92 3.17e-02 GO:0034774 secretory granule lumen
12.40 3.71e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
4.00 2.41e-02 GO:0045202 synapse
3.54 6.01e-04 GO:0005615 extracellular space
3.05 1.36e-03 GO:0044421 extracellular region part
2.28 2.18e-03 GO:0005576 extracellular region
1.98 4.80e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
46.49 4.61e-03 GO:0050997 quaternary ammonium group binding