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Motif ID: T.p2

Z-value: 1.610

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_54320083	14.203	NM_002104	GZMK	granzyme K (granzyme 3; tryptase II)
chr14_-_107113943	11.666		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_128913881	10.445	NM_018990	SASH3	SAM and SH3 domain containing 3
chr14_-_107013474	10.375		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_130536417	9.761	NM_152552	SAMD3	sterile alpha motif domain containing 3
chr4_-_74847669	8.953	NM_002619	PF4	platelet factor 4
chrX_+_128913897	8.729		SASH3	SAM and SH3 domain containing 3
chr17_+_34431219	8.376	NM_002984	CCL4	chemokine (C-C motif) ligand 4
chr14_-_107211131	7.826		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_209941894	7.709		TRAF3IP3	TRAF3 interacting protein 3
chr1_-_205290756	7.401	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr5_-_39270708	6.942	NM_001243093	FYB	FYN binding protein
chr17_-_43502992	6.692	NM_199282	ARHGAP27	Rho GTPase activating protein 27
chr12_-_53074172	6.392	NM_006121	KRT1	keratin 1
chr2_-_219031646	6.199	NM_000634	CXCR1	chemokine (C-X-C motif) receptor 1
chr9_+_135894806	6.094		EEF1A1	eukaryotic translation elongation factor 1 alpha 1
chr6_+_167536240	5.901	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr1_-_114414245	5.657	NM_001193431 NM_012411 NM_015967	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr17_+_25958217	5.584		LGALS9	lectin, galactoside-binding, soluble, 9
chr1_-_200992510	5.560		KIF21B	kinesin family member 21B
chr9_-_37034358	5.321	NM_016734	PAX5	paired box 5
chr17_+_25958245	5.228		LGALS9	lectin, galactoside-binding, soluble, 9
chr11_-_111249902	5.169		POU2AF1	POU class 2 associating factor 1
chr17_+_34538464	5.134	NM_207007 NM_001001435	CCL4L2 CCL4L1	chemokine (C-C motif) ligand 4-like 2 chemokine (C-C motif) ligand 4-like 1
chrX_-_19688991	5.007	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr6_-_74229094	4.844		EEF1A1	eukaryotic translation elongation factor 1 alpha 1
chr17_+_25958151	4.680	NM_002308 NM_009587	LGALS9	lectin, galactoside-binding, soluble, 9
chr17_+_25958192	4.629		LGALS9	lectin, galactoside-binding, soluble, 9
chr5_+_96212167	4.532		ERAP2	endoplasmic reticulum aminopeptidase 2
chr2_-_152146373	4.451	NM_004688	NMI	N-myc (and STAT) interactor
chr11_+_69061599	4.328	NM_138768	MYEOV	myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chrX_+_37639306	4.175		CYBB	cytochrome b-245, beta polypeptide
chr1_-_26633110	3.934	NM_001077262 NM_183008	UBXN11	UBX domain protein 11
chr14_-_106994001	3.845		IGHV3-48 IGH@ IGHA1 IGHM	immunoglobulin heavy variable 3-48 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant mu
chr14_-_106692107	3.808		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr17_+_25958257	3.700		LGALS9	lectin, galactoside-binding, soluble, 9
chr19_-_17958773	3.645		JAK3	Janus kinase 3
chr2_-_100722328	3.594		AFF3	AF4/FMR2 family, member 3
chr16_-_67965754	3.391	NM_001907	CTRL	chymotrypsin-like
chr5_+_96211643	3.353	NM_001130140 NM_022350	ERAP2	endoplasmic reticulum aminopeptidase 2
chr16_+_12058963	3.301	NM_001192	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr14_-_24809031	3.216	NM_006871	RIPK3	receptor-interacting serine-threonine kinase 3
chr1_-_27953046	3.146	NM_001042729	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr7_-_36764000	3.025	NM_001177506 NM_001177507 NM_001637	AOAH	acyloxyacyl hydrolase (neutrophil)
chr12_+_69742140	2.969		LYZ	lysozyme
chr14_-_106714594	2.884
chr9_+_26066672	2.860	NM_001004352	LOC100506422	putative deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323
chr19_-_44174497	2.830	NM_001005376 NM_001005377 NM_002659	PLAUR	plasminogen activator, urokinase receptor
chr12_-_1920892	2.628		CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr17_+_56414563	2.616		LOC100506779	uncharacterized LOC100506779
chr9_-_117150217	2.511		AKNA	AT-hook transcription factor
chr16_+_69220940	2.509	NM_006750	SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr14_-_107218786	2.506		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr2_-_37544165	2.495	NM_005813	PRKD3	protein kinase D3
chr14_+_75894508	2.470	NM_001135047	JDP2	Jun dimerization protein 2
chr3_+_137728949	2.467	NM_016369	CLDN18	claudin 18
chr3_+_47029453	2.419		NBEAL2	neurobeachin-like 2
chrY_+_21729214	2.414		TXLNG2P	taxilin gamma 2, pseudogene
chr19_+_17638064	2.337		FAM129C	family with sequence similarity 129, member C
chr14_-_106725620	2.287		IGHV4-31 IGHV3-23 IGHA1 IGHG1 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-23 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr12_-_7848324	2.271	NM_020634	GDF3	growth differentiation factor 3
chr19_-_13947101	2.233		LOC284454	uncharacterized LOC284454
chr10_+_70847817	2.225	NM_002727	SRGN	serglycin
chr22_+_22676814	2.222
chr5_-_138725544	2.214	NM_016459	MZB1	marginal zone B and B1 cell-specific protein
chr4_+_74719012	2.202	NM_002620	PF4V1	platelet factor 4 variant 1
chr7_-_28220342	2.129	NM_175061	JAZF1	JAZF zinc finger 1
chr5_+_35856990	2.104	NM_002185	IL7R	interleukin 7 receptor
chr5_-_39203061	2.095		FYB	FYN binding protein
chr12_+_69742130	2.074	NM_000239	LYZ	lysozyme
chr10_+_70847857	2.060		SRGN	serglycin
chrX_+_16804531	2.060	NM_001168683 NM_018360	TXLNG	taxilin gamma
chr20_+_35973083	1.999	NM_005417	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr7_-_81399286	1.983	NM_000601 NM_001010931 NM_001010932 NM_001010933 NM_001010934	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_-_106725232	1.903		ZCWPW2 IGHV3-23 IGKV3-20 IGK@	zinc finger, CW type with PWWP domain 2 immunoglobulin heavy variable 3-23 immunoglobulin kappa variable 3-20 immunoglobulin kappa locus
chr11_-_59950498	1.858	NM_022349 NM_152851	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A
chr11_-_66112537	1.855	NM_001024957 NM_015399	BRMS1	breast cancer metastasis suppressor 1
chr11_+_60223281	1.841	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr1_-_161039586	1.840		ARHGAP30	Rho GTPase activating protein 30
chr6_-_97731051	1.827	NM_198468	MMS22L	MMS22-like, DNA repair protein
chr1_+_192127591	1.820	NM_130782	RGS18	regulator of G-protein signaling 18
chr17_+_7461591	1.747	NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13
chr11_-_44972227	1.730	NM_001076787 NM_006034	TP53I11	tumor protein p53 inducible protein 11
chr8_-_145060563	1.698		PARP10	poly (ADP-ribose) polymerase family, member 10
chr19_+_55281262	1.679	NM_014218	KIR2DL1 KIR2DS4	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
chr1_+_28585959	1.677	NM_031459	SESN2	sestrin 2
chr8_-_145060594	1.661	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr11_+_122709205	1.661	NM_019604	CRTAM	cytotoxic and regulatory T cell molecule
chr14_-_107078578	1.625
chr14_-_106691698	1.603
chr1_+_174844655	1.592	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr11_-_111750144	1.588	NM_138378	FDXACB1	ferredoxin-fold anticodon binding domain containing 1
chr1_-_161039413	1.553		ARHGAP30	Rho GTPase activating protein 30
chr19_-_54311958	1.548	NM_033297	NLRP12	NLR family, pyrin domain containing 12
chr1_-_12908141	1.518	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr11_+_68857483	1.500
chr5_+_14664764	1.463	NM_138348	FAM105B	family with sequence similarity 105, member B
chr17_-_40306988	1.446		RAB5C	RAB5C, member RAS oncogene family
chr4_-_5711274	1.441	NM_001166136	EVC2	Ellis van Creveld syndrome 2
chr12_-_120687956	1.425	NM_025157	PXN	paxillin
chr10_-_23003443	1.418	NM_005028	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr2_+_171571936	1.373
chr4_+_155484131	1.364	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr9_+_75766777	1.346	NM_000700	ANXA1	annexin A1
chr2_+_171571800	1.342	NM_001003845	SP5	Sp5 transcription factor
chr3_-_10332408	1.316	NM_001134941 NM_016362	GHRL	ghrelin/obestatin prepropeptide
chr17_-_40306935	1.294		RAB5C	RAB5C, member RAS oncogene family
chr17_-_79881304	1.293	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr11_-_111749810	1.239		FDXACB1	ferredoxin-fold anticodon binding domain containing 1
chr3_+_128532267	1.236
chr20_-_50179338	1.220		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr16_-_4323055	1.207		TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr4_-_151936648	1.198	NM_006726	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr19_+_2289996	1.194
chr7_+_143013218	1.183	NM_000083	CLCN1	chloride channel 1, skeletal muscle
chr10_+_135051407	1.178	NM_014468	VENTX	VENT homeobox
chr7_-_5570188	1.175	NM_001101	ACTB	actin, beta
chr9_+_75766794	1.162		ANXA1	annexin A1
chr16_+_77233348	1.161	NM_001129979	SYCE1L	synaptonemal complex central element protein 1-like
chr19_-_11688508	1.142	NM_001611	ACP5	acid phosphatase 5, tartrate resistant
chr10_-_125853102	1.116		CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr15_-_80263460	1.110	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr1_+_27101217	1.103		ARID1A	AT rich interactive domain 1A (SWI-like)
chr4_-_151936864	1.096		LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chrX_+_57313109	1.084	NM_174912	FAAH2	fatty acid amide hydrolase 2
chr7_+_17382900	1.083		AHR	aryl hydrocarbon receptor
chr2_+_219246751	1.077	NM_000578	SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr17_+_56406294	1.070		LOC100506779	uncharacterized LOC100506779
chr16_-_4323000	1.067	NM_003223	TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr19_-_58864820	1.063	NM_130786	A1BG	alpha-1-B glycoprotein
chr1_-_1141932	1.057	NM_004195 NM_148901 NM_148902	TNFRSF18	tumor necrosis factor receptor superfamily, member 18
chr19_+_7828034	1.055	NM_001144904 NM_001144905 NM_001144906 NM_001144907 NM_001144908 NM_001144909 NM_001144910 NM_001144911 NM_014257	CLEC4M	C-type lectin domain family 4, member M
chr15_-_40600025	1.005		PLCB2	phospholipase C, beta 2
chr15_-_31523049	0.995	NM_001243538	LOC283710	uncharacterized LOC283710
chr17_+_57970442	0.992	NM_003161	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr6_+_109762204	0.986		SMPD2	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr17_+_34640030	0.984	NM_207007 NM_001001435	CCL4L2 CCL4L1	chemokine (C-C motif) ligand 4-like 2 chemokine (C-C motif) ligand 4-like 1
chr20_-_52199635	0.982	NM_006526	ZNF217	zinc finger protein 217
chr4_+_153864134	0.976	NM_033393	FHDC1	FH2 domain containing 1
chr5_-_49737198	0.972		EMB	embigin
chr19_-_11688441	0.952		ACP5	acid phosphatase 5, tartrate resistant
chr5_+_14664803	0.947		FAM105B	family with sequence similarity 105, member B
chr10_+_111765725	0.927	NM_019903	ADD3	adducin 3 (gamma)
chr9_+_141106636	0.924	NM_001145249	FAM157B	family with sequence similarity 157, member B
chr21_-_15918635	0.923	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_128222175	0.923	NM_001010923 NM_001164685	THEMIS	thymocyte selection associated
chr6_+_132873829	0.922	NM_053278	TAAR8	trace amine associated receptor 8
chr20_-_62199106	0.917	NM_033405	PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285
chr1_+_39456887	0.895	NM_001136275 NM_024595	AKIRIN1	akirin 1
chr1_+_45266048	0.875		PLK3	polo-like kinase 3
chr1_+_66797775	0.873	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chr6_-_32634287	0.871	NM_001243961 NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr8_-_143833924	0.857	NM_205545	LYPD2	LY6/PLAUR domain containing 2
chr6_-_6320875	0.846		F13A1	coagulation factor XIII, A1 polypeptide
chr17_-_40307015	0.846	NM_001252039 NM_004583 NM_201434	RAB5C	RAB5C, member RAS oncogene family
chr19_-_44174271	0.845		PLAUR	plasminogen activator, urokinase receptor
chr8_-_119123804	0.839	NM_000127	EXT1	exostosin 1
chr7_+_99816870	0.833	NM_024070	PVRIG	poliovirus receptor related immunoglobulin domain containing
chr5_-_49737216	0.832	NM_198449	EMB	embigin
chr12_+_56324945	0.826	NM_001345	DGKA	diacylglycerol kinase, alpha 80kDa
chr16_-_88717395	0.818	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr19_-_44285012	0.813		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr5_-_138718941	0.813		SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr6_-_31681845	0.811
chr1_-_40562917	0.809		PPT1	palmitoyl-protein thioesterase 1
chr8_+_22019167	0.789	NM_001172357 NM_001172410 NM_003018	SFTPC	surfactant protein C
chr17_+_7462064	0.770		TNFSF13	tumor necrosis factor (ligand) superfamily, member 13
chr2_+_228678556	0.767	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr3_-_71542628	0.766		FOXP1	forkhead box P1
chr1_-_205601999	0.753	NM_001973 NM_021795	ELK4	ELK4, ETS-domain protein (SRF accessory protein 1)
chr16_+_56995761	0.738	NM_000078	CETP	cholesteryl ester transfer protein, plasma
chr17_+_1619816	0.726	NM_001163673 NM_152348	WDR81	WD repeat domain 81
chr14_-_51411118	0.715	NM_001163940 NM_002863	PYGL	phosphorylase, glycogen, liver
chr9_-_130533509	0.709	NM_001252334 NM_005489	SH2D3C	SH2 domain containing 3C
chrY_+_24636543	0.682	NM_001002758 NM_004676	PRY2 PRY	PTPN13-like, Y-linked 2 PTPN13-like, Y-linked
chr7_+_72396799	0.673		POM121	POM121 membrane glycoprotein
chr1_-_40562909	0.672		PPT1	palmitoyl-protein thioesterase 1
chr1_+_156123321	0.663	NM_001193300 NM_022367 NM_001193302	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_+_11546085	0.656	NM_001001329 NM_002743	PRKCSH	protein kinase C substrate 80K-H
chr10_+_114133838	0.654	NM_203379	ACSL5	acyl-CoA synthetase long-chain family member 5
chr4_+_160188997	0.644	NM_014247	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2
chr15_+_91411884	0.640	NM_002569	FURIN	furin (paired basic amino acid cleaving enzyme)
chr1_+_174933904	0.639	NM_001243764	RABGAP1L	RAB GTPase activating protein 1-like
chr12_-_51663969	0.630	NM_001033873 NM_001031628	SMAGP	small cell adhesion glycoprotein
chr15_-_34502269	0.625	NM_024713	C15orf29	chromosome 15 open reading frame 29
chr10_+_11047253	0.612	NM_001025077	CELF2	CUGBP, Elav-like family member 2
chrY_-_24242153	0.611	NM_001002758 NM_004676	PRY2 PRY	PTPN13-like, Y-linked 2 PTPN13-like, Y-linked
chr1_+_45266035	0.610	NM_004073	PLK3	polo-like kinase 3
chr3_-_58200397	0.589	NM_004944	DNASE1L3	deoxyribonuclease I-like 3
chr17_-_61523544	0.584	NM_001017916 NM_001915	CYB561	cytochrome b-561
chr11_+_60524339	0.583	NM_001098835 NM_152717	MS4A15	membrane-spanning 4-domains, subfamily A, member 15
chr12_+_96252705	0.582	NM_003095	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr19_+_55174123	0.575	NM_001081438 NM_006847	LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
chr11_+_129685732	0.574	NM_138788	TMEM45B	transmembrane protein 45B
chr17_+_7482961	0.572		CD68	CD68 molecule
chr17_+_7482938	0.571		CD68	CD68 molecule
chr20_+_825284	0.566	NM_031424	FAM110A	family with sequence similarity 110, member A
chrX_+_23685658	0.561		PRDX4	peroxiredoxin 4
chr3_+_52812438	0.558	NM_001166434	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr11_+_59856136	0.556	NM_000139	MS4A2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
5.12	6.11e-07	GO:0006955	immune response
3.92	9.51e-07	GO:0002376	immune system process
1.78	4.86e-05	GO:0050896	response to stimulus
3.65	1.57e-03	GO:0009611	response to wounding
87.06	1.93e-03	GO:0032692	negative regulation of interleukin-1 production
3.87	6.70e-03	GO:0002682	regulation of immune system process
6.13	8.12e-03	GO:0001817	regulation of cytokine production
2.49	8.77e-03	GO:0048583	regulation of response to stimulus
5.90	1.10e-02	GO:0006954	inflammatory response
4.66	1.17e-02	GO:0050776	regulation of immune response
14.52	1.24e-02	GO:0050864	regulation of B cell activation
6.74	1.26e-02	GO:0051249	regulation of lymphocyte activation
6.12	2.52e-02	GO:0002694	regulation of leukocyte activation
2.17	2.76e-02	GO:0006950	response to stress
4.22	2.89e-02	GO:0001775	cell activation
5.89	3.31e-02	GO:0050865	regulation of cell activation
18.34	3.41e-02	GO:0030888	regulation of B cell proliferation
18.34	3.41e-02	GO:0050707	regulation of cytokine secretion
16.99	4.62e-02	GO:0050871	positive regulation of B cell activation

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.29	4.03e-03	GO:0005576	extracellular region
14.83	1.36e-02	GO:0031093	platelet alpha granule lumen
14.52	1.48e-02	GO:0034774	secretory granule lumen
13.94	1.73e-02	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
13.40	2.02e-02	GO:0031983	vesicle lumen
12.23	2.88e-02	GO:0031091	platelet alpha granule

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
30.48	3.09e-07	GO:0003823	antigen binding
15.15	1.70e-02	GO:0008009	chemokine activity
13.66	2.54e-02	GO:0042379	chemokine receptor binding