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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: TBP.p2

Z-value: 4.533

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_142829169	30.403	NM_002652	PIP	prolactin-induced protein
chr11_+_18287807	24.664	NM_000331 NM_001178006 NM_199161	SAA1	serum amyloid A1
chr11_-_18270167	24.602	NM_001199744 NM_001127380 NM_030754	SAA2-SAA4 SAA2	SAA2-SAA4 readthrough serum amyloid A2
chr1_-_59042827	16.187		TACSTD2	tumor-associated calcium signal transducer 2
chr3_+_193853930	15.115	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr12_+_52627007	14.659		KRT7	keratin 7
chr21_-_43735462	14.357		TFF3	trefoil factor 3 (intestinal)
chr19_+_18496966	14.303	NM_004864	GDF15	growth differentiation factor 15
chr11_-_5248180	13.687	NM_000518	HBB	hemoglobin, beta
chr17_-_39780762	13.363	NM_000422	KRT17	keratin 17
chr3_+_193853937	13.330		HES1	hairy and enhancer of split 1, (Drosophila)
chr2_-_151344145	13.217	NM_005168	RND3	Rho family GTPase 3
chr16_-_56701904	12.639	NM_005950	MT1G	metallothionein 1G
chr21_-_43735705	12.636	NM_003226	TFF3	trefoil factor 3 (intestinal)
chr15_-_62457481	12.617	NM_001007595	C2CD4B	C2 calcium-dependent domain containing 4B
chr17_+_32683470	11.798	NM_005408	CCL13	chemokine (C-C motif) ligand 13
chr2_-_216300770	11.602	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr19_-_36247917	11.589	NM_144617	HSPB6	heat shock protein, alpha-crystallin-related, B6
chr15_+_45722762	11.500	NM_032413 NM_197955	C15orf48	chromosome 15 open reading frame 48
chr17_-_34344933	11.425	NM_005064 NM_145898	CCL23	chemokine (C-C motif) ligand 23
chr12_-_53298765	11.311	NM_002273	KRT8	keratin 8
chr12_-_15038724	11.250	NM_000900 NM_001190839	MGP	matrix Gla protein
chr12_-_11463353	11.219	NM_002723	PRB4	proline-rich protein BstNI subfamily 4
chr11_+_43963809	11.155	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr16_+_56672577	11.094	NM_005946	MT1A	metallothionein 1A
chr7_+_100770378	10.910	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr17_-_48278987	10.601	NM_000088	COL1A1	collagen, type I, alpha 1
chr3_+_149192479	10.359		TM4SF4	transmembrane 4 L six family member 4
chr11_-_5255712	10.298	NM_000519	HBD	hemoglobin, delta
chr6_+_31913852	10.062		CFB	complement factor B
chr8_-_6735438	9.984	NM_005218	DEFB1	defensin, beta 1
chr7_-_16844606	9.984	NM_006408	AGR2	anterior gradient 2 homolog (Xenopus laevis)
chr14_-_53417808	9.939	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr1_-_169703178	9.512	NM_000450	SELE	selectin E
chr19_+_840970	9.483	NM_002777	PRTN3	proteinase 3
chr1_-_168698412	9.478	NM_001937	DPT	dermatopontin
chr6_+_32006092	9.416	NM_000500 NM_001128590	CYP21A2	cytochrome P450, family 21, subfamily A, polypeptide 2
chr5_-_42811959	9.188	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr10_+_81370694	9.105	NM_001093770 NM_001164644 NM_001164645 NM_001164646 NM_001164647 NM_005411	SFTPA1	surfactant protein A1
chr10_-_45474210	9.105	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr4_+_25657434	9.068	NM_001177998 NM_006424	SLC34A2	solute carrier family 34 (sodium phosphate), member 2
chr19_-_41356193	9.053	NM_000762	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6
chr5_+_78407603	9.036	NM_001713	BHMT	betaine--homocysteine S-methyltransferase
chr19_+_41430123	8.740		CYP2B7P1	cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr6_+_132129154	8.735	NM_006208	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr11_-_102651321	8.592	NM_002425	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr3_+_148583042	8.548	NM_001870	CPA3	carboxypeptidase A3 (mast cell)
chr17_-_39661803	8.461	NM_002274 NM_153490	KRT13	keratin 13
chr16_+_215972	8.451	NM_001003938	HBM	hemoglobin, mu
chr12_-_52886971	8.415	NM_005554	KRT6A	keratin 6A
chr7_+_94024201	8.352		COL1A2	collagen, type I, alpha 2
chr1_-_20306093	8.285	NM_001161729	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)
chr16_+_1290677	8.138	NM_003294	TPSB2 TPSAB1	tryptase beta 2 (gene/pseudogene) tryptase alpha/beta 1
chr11_-_2182408	8.025	NM_000207 NM_001185097 NM_001185098 NM_001042376	INS INS-IGF2	insulin INS-IGF2 readthrough
chr21_-_43786602	7.979	NM_003225	TFF1	trefoil factor 1
chr11_-_2950593	7.918	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr16_-_1280162	7.545	NM_024164	TPSB2 TPSAB1	tryptase beta 2 (gene/pseudogene) tryptase alpha/beta 1
chr4_-_74964836	7.508		CXCL2	chemokine (C-X-C motif) ligand 2
chr9_+_130911731	7.428	NM_005564	LCN2	lipocalin 2
chr12_+_13044352	7.403		GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr8_-_82395401	7.368	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr11_-_102714240	7.347	NM_002422	MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr20_+_30193083	7.320	NM_002165 NM_181353	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr13_+_53602829	7.309	NM_006418	OLFM4	olfactomedin 4
chr11_-_102826433	7.285	NM_002427	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr1_-_230849863	7.106		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr11_-_76381787	7.076	NM_001128922	LRRC32	leucine rich repeat containing 32
chr15_+_75041182	7.066	NM_000761	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2
chr7_+_30951414	6.887	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr20_+_3052265	6.842	NM_000915	OXT	oxytocin, prepropeptide
chr6_+_127898318	6.737	NM_001010905	C6orf58	chromosome 6 open reading frame 58
chr21_+_47518012	6.633	NM_001849 NM_058174 NM_058175	COL6A2	collagen, type VI, alpha 2
chr15_+_62359175	6.621	NM_207322	C2CD4A	C2 calcium-dependent domain containing 4A
chr5_-_115152322	6.556	NM_001801	CDO1	cysteine dioxygenase, type I
chr17_-_48278874	6.500		COL1A1	collagen, type I, alpha 1
chr19_+_41497182	6.378	NM_000767	CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chr9_-_117880411	6.259	NM_002160	TNC	tenascin C
chr2_+_228678556	6.251	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr12_-_52867521	6.223	NM_173086	KRT6C	keratin 6C
chr16_-_15950850	6.194	NM_001040113 NM_001040114 NM_002474 NM_022844	MYH11	myosin, heavy chain 11, smooth muscle
chr20_-_44540685	6.106		PLTP	phospholipid transfer protein
chr1_-_95007139	6.055	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr4_-_74904329	6.020	NM_002090	CXCL3	chemokine (C-X-C motif) ligand 3
chr6_+_131894343	6.008	NM_000045 NM_001244438	ARG1	arginase, liver
chr16_+_78056411	5.978	NM_005752	CLEC3A	C-type lectin domain family 3, member A
chr16_+_71392615	5.970	NM_001740 NM_007088	CALB2	calbindin 2
chr15_+_41221530	5.965	NM_019074	DLL4	delta-like 4 (Drosophila)
chr1_+_161228516	5.905	NM_001102566	PCP4L1	Purkinje cell protein 4 like 1
chr3_+_148415657	5.866	NM_000685 NM_004835 NM_009585 NM_031850	AGTR1	angiotensin II receptor, type 1
chr17_+_32612686	5.790	NM_002986	CCL11	chemokine (C-C motif) ligand 11
chr19_-_6720585	5.774	NM_000064	C3	complement component 3
chr19_-_18902077	5.737	NM_000095	COMP	cartilage oligomeric matrix protein
chr7_-_94285477	5.708	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr10_-_100027943	5.664	NM_032211	LOXL4	lysyl oxidase-like 4
chr5_-_54468833	5.640	NM_001145734 NM_001170402 NM_152623	CDC20B	cell division cycle 20 homolog B (S. cerevisiae)
chr15_-_63674074	5.565	NM_001218 NM_206925	CA12	carbonic anhydrase XII
chr17_-_48546174	5.563	NM_001267	CHAD	chondroadherin
chr20_+_238376	5.518	NM_207469	DEFB132	defensin, beta 132
chr16_+_56716378	5.457	NM_005952	MT1X	metallothionein 1X
chr10_+_17851342	5.407	NM_002438	MRC1	mannose receptor, C type 1
chr19_+_840963	5.338		PRTN3	proteinase 3
chr7_-_94285372	5.301		SGCE	sarcoglycan, epsilon
chr12_-_88974094	5.270	NM_000899 NM_003994	KITLG	KIT ligand
chr20_+_31823801	5.244	NM_001243193 NM_016583 NM_130852	BPIFA1	BPI fold containing family A, member 1
chr7_-_94285426	5.216		SGCE	sarcoglycan, epsilon
chr22_+_31480981	5.173	NM_001207018	SMTN	smoothelin
chr10_+_96698409	5.122	NM_000771	CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
chr18_+_56887389	5.023	NM_001012512 NM_001012513 NM_002091	GRP	gastrin-releasing peptide
chr16_+_57406398	4.975	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr17_-_39041436	4.967	NM_019010	KRT20	keratin 20
chr19_+_46367517	4.946	NM_004497	FOXA3	forkhead box A3
chr17_-_39684499	4.910		KRT19	keratin 19
chr3_-_195310770	4.842		APOD	apolipoprotein D
chr1_+_86046434	4.827	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr1_-_230849847	4.822		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_8086347	4.755		ERRFI1	ERBB receptor feedback inhibitor 1
chr8_+_22019167	4.752	NM_001172357 NM_001172410 NM_003018	SFTPC	surfactant protein C
chr1_+_152881022	4.643	NM_005547	IVL	involucrin
chr17_+_38171613	4.641	NM_000759 NM_001178147 NM_172219 NM_172220	CSF3	colony stimulating factor 3 (granulocyte)
chr19_+_41594367	4.619	NM_000766	CYP2A13	cytochrome P450, family 2, subfamily A, polypeptide 13
chr16_+_71392637	4.608		CALB2	calbindin 2
chr8_-_86253863	4.607	NM_001164830	CA1	carbonic anhydrase I
chr16_+_56659679	4.575		MT1E	metallothionein 1E
chr17_-_39675078	4.433	NM_002275	KRT15	keratin 15
chr11_+_61976139	4.419	NM_002407	SCGB2A1	secretoglobin, family 2A, member 1
chr12_+_11081833	4.388	NM_005042 NM_001110213	PRH2	proline-rich protein HaeIII subfamily 2
chr15_-_63673918	4.387		CA12	carbonic anhydrase XII
chr8_+_19796840	4.273		LPL	lipoprotein lipase
chr17_+_32582295	4.269	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr9_+_117092068	4.242	NM_000608	ORM2	orosomucoid 2
chr11_+_75273245	4.215		SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr9_-_33447527	4.214	NM_004925	AQP3	aquaporin 3 (Gill blood group)
chr12_-_52845862	4.168	NM_005555	KRT6B	keratin 6B
chr16_+_56659584	4.156	NM_175617	MT1E	metallothionein 1E
chr7_+_75931991	4.150		HSPB1	heat shock 27kDa protein 1
chr8_-_23021447	4.128	NM_003840	TNFRSF10D	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr2_-_21266809	4.119		APOB	apolipoprotein B (including Ag(x) antigen)
chrX_+_46940235	4.086		RGN	regucalcin (senescence marker protein-30)
chr10_+_96522457	4.062	NM_000769	CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
chr1_-_201465700	4.057	NM_001193572	CSRP1	cysteine and glycine-rich protein 1
chr1_+_16085245	4.022	NM_017556	FBLIM1	filamin binding LIM protein 1
chr19_+_859658	3.999	NM_001928	CFD	complement factor D (adipsin)
chr1_-_153029987	3.997	NM_005988	SPRR2A	small proline-rich protein 2A
chr9_-_34691135	3.994	NM_006274	CCL19	chemokine (C-C motif) ligand 19
chr7_+_127881330	3.992	NM_000230	LEP	leptin
chr11_-_116693907	3.938	NM_000482	APOA4	apolipoprotein A-IV
chr20_-_43977023	3.888	NM_002999	SDC4	syndecan 4
chr6_+_19837599	3.887	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr1_+_186265404	3.855	NM_001127708 NM_001127709 NM_001127710 NM_005807	PRG4	proteoglycan 4
chr19_-_39303739	3.831	NM_006149	LGALS4	lectin, galactoside-binding, soluble, 4
chr2_-_21266915	3.828	NM_000384	APOB	apolipoprotein B (including Ag(x) antigen)
chr11_-_102595623	3.827	NM_002424	MMP8	matrix metallopeptidase 8 (neutrophil collagenase)
chr5_-_179780314	3.808	NM_005110	GFPT2	glutamine-fructose-6-phosphate transaminase 2
chr17_-_39768939	3.770	NM_005557	KRT16	keratin 16
chr4_-_107957452	3.763	NM_014421	DKK2	dickkopf 2 homolog (Xenopus laevis)
chr5_+_132209354	3.673	NM_052971	LEAP2	liver expressed antimicrobial peptide 2
chr7_-_41742666	3.665	NM_002192	INHBA	inhibin, beta A
chr11_+_62037629	3.654	NM_002411	SCGB2A2	secretoglobin, family 2A, member 2
chr9_+_117085302	3.643	NM_000607	ORM1	orosomucoid 1
chr16_+_202853	3.634	NM_005332	HBZ	hemoglobin, zeta
chr11_+_1074869	3.632	NM_002457	MUC2	mucin 2, oligomeric mucus/gel-forming
chr1_+_192544856	3.619	NM_002922	RGS1	regulator of G-protein signaling 1
chr19_+_10381763	3.592		ICAM1	intercellular adhesion molecule 1
chr6_-_30080866	3.572	NM_007028	TRIM31	tripartite motif containing 31
chr9_+_139557378	3.535	NM_016215	EGFL7	EGF-like-domain, multiple 7
chr6_+_26156558	3.518	NM_005321	HIST1H1E	histone cluster 1, H1e
chr6_-_27860927	3.513	NM_003514	HIST1H2AM	histone cluster 1, H2am
chr12_-_11548485	3.507	NM_006248	PRB1 PRB2	proline-rich protein BstNI subfamily 1 proline-rich protein BstNI subfamily 2
chr2_-_75426613	3.492	NM_001058 NM_015727	TACR1	tachykinin receptor 1
chr12_+_50344523	3.486	NM_000486	AQP2	aquaporin 2 (collecting duct)
chr17_+_38599651	3.428	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr12_-_53074172	3.403	NM_006121	KRT1	keratin 1
chr11_-_62457001	3.391		LRRN4CL	LRRN4 C-terminal like
chr8_-_27472188	3.387		CLU	clusterin
chr8_-_23261626	3.380		LOXL2	lysyl oxidase-like 2
chr11_-_102745666	3.339	NM_002426	MMP12	matrix metallopeptidase 12 (macrophage elastase)
chr10_+_24497719	3.300	NM_001098501 NM_019590	KIAA1217	KIAA1217
chr15_-_75017710	3.292	NM_000499	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1
chr12_-_7281374	3.257	NM_031491	RBP5	retinol binding protein 5, cellular
chr1_+_149822627	3.253	NM_001040874 NM_003516	HIST2H2AA4 HIST2H2AA3	histone cluster 2, H2aa4 histone cluster 2, H2aa3
chr7_+_75931829	3.232	NM_001540	HSPB1	heat shock 27kDa protein 1
chr19_+_13049413	3.210	NM_004343	CALR	calreticulin
chr8_-_23261632	3.209		LOXL2	lysyl oxidase-like 2
chr10_+_18098332	3.169	NM_002438	MRC1	mannose receptor, C type 1
chr6_-_26189303	3.161	NM_003539	HIST1H4D	histone cluster 1, H4d
chr8_-_23261591	3.138		LOXL2	lysyl oxidase-like 2
chr7_-_559479	3.135	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr11_+_65190267	3.119		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr17_-_79818406	3.115		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr11_-_4718948	3.109	NM_030774	OR51E2	olfactory receptor, family 51, subfamily E, member 2
chr19_-_33793441	3.106		CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha
chr19_-_33793429	3.075	NM_004364	CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha
chr19_+_12902286	3.069
chr21_-_28217272	3.056		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_-_33793321	3.038
chr1_-_149814264	3.038	NM_001040874 NM_003516	HIST2H2AA4 HIST2H2AA3	histone cluster 2, H2aa4 histone cluster 2, H2aa3
chr6_+_153071931	2.956	NM_003381 NM_194435	VIP	vasoactive intestinal peptide
chr1_+_17575592	2.949	NM_016233	PADI3	peptidyl arginine deiminase, type III
chr7_+_24323806	2.946	NM_000905	NPY	neuropeptide Y
chr1_+_40420802	2.942		MFSD2A	major facilitator superfamily domain containing 2A

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.63	5.36e-18	GO:0042221	response to chemical stimulus
3.35	5.24e-12	GO:0070887	cellular response to chemical stimulus
2.24	1.83e-11	GO:0006950	response to stress
1.70	3.37e-11	GO:0032501	multicellular organismal process
1.89	5.23e-11	GO:0032502	developmental process
3.40	1.38e-10	GO:0006952	defense response
1.98	2.33e-10	GO:0048856	anatomical structure development
1.58	3.40e-10	GO:0050896	response to stimulus
2.37	4.96e-10	GO:0048513	organ development
5.57	5.33e-10	GO:0010035	response to inorganic substance
5.43	1.01e-09	GO:0006954	inflammatory response
1.88	1.94e-09	GO:0007275	multicellular organismal development
2.00	4.02e-09	GO:0048731	system development
3.68	4.14e-09	GO:0009725	response to hormone stimulus
3.09	4.48e-09	GO:0009611	response to wounding
3.44	1.64e-08	GO:0009719	response to endogenous stimulus
2.63	1.88e-08	GO:0010033	response to organic substance
2.88	3.10e-08	GO:0009605	response to external stimulus
3.44	1.03e-07	GO:0048878	chemical homeostasis
2.10	1.25e-07	GO:0065008	regulation of biological quality
11.88	3.40e-07	GO:0002526	acute inflammatory response
2.78	4.48e-07	GO:0042127	regulation of cell proliferation
2.80	9.20e-07	GO:0050793	regulation of developmental process
5.15	1.07e-06	GO:0032101	regulation of response to external stimulus
40.08	1.62e-06	GO:0042738	exogenous drug catabolic process
1.65	1.78e-06	GO:0051716	cellular response to stimulus
3.81	3.37e-06	GO:0051707	response to other organism
3.48	3.51e-06	GO:0009607	response to biotic stimulus
2.76	3.80e-06	GO:0042592	homeostatic process
19.44	4.96e-06	GO:0034367	macromolecular complex remodeling
19.44	4.96e-06	GO:0034368	protein-lipid complex remodeling
19.44	4.96e-06	GO:0034369	plasma lipoprotein particle remodeling
4.70	5.70e-06	GO:0009617	response to bacterium
2.71	6.31e-06	GO:0051704	multi-organism process
2.75	6.41e-06	GO:0009888	tissue development
2.36	7.49e-06	GO:0051239	regulation of multicellular organismal process
4.17	1.01e-05	GO:0009991	response to extracellular stimulus
32.07	1.18e-05	GO:0042737	drug catabolic process
4.31	1.19e-05	GO:0031667	response to nutrient levels
3.53	1.72e-05	GO:0051094	positive regulation of developmental process
4.40	1.81e-05	GO:0048545	response to steroid hormone stimulus
16.45	2.27e-05	GO:0071825	protein-lipid complex subunit organization
16.45	2.27e-05	GO:0071827	plasma lipoprotein particle organization
15.27	4.37e-05	GO:0070301	cellular response to hydrogen peroxide
1.79	5.90e-05	GO:0048518	positive regulation of biological process
3.31	6.53e-05	GO:0009628	response to abiotic stimulus
6.68	9.55e-05	GO:0008217	regulation of blood pressure
5.22	1.01e-04	GO:0010038	response to metal ion
6.56	1.20e-04	GO:0050727	regulation of inflammatory response
2.68	1.94e-04	GO:2000026	regulation of multicellular organismal development
15.59	2.85e-04	GO:0017144	drug metabolic process
15.59	2.85e-04	GO:0042743	hydrogen peroxide metabolic process
12.22	2.96e-04	GO:0097006	regulation of plasma lipoprotein particle levels
2.08	3.28e-04	GO:0009653	anatomical structure morphogenesis
4.02	3.91e-04	GO:0006875	cellular metal ion homeostasis
4.73	3.97e-04	GO:0006979	response to oxidative stress
8.22	4.55e-04	GO:0042542	response to hydrogen peroxide
2.86	4.63e-04	GO:0009887	organ morphogenesis
2.37	5.59e-04	GO:0032879	regulation of localization
5.27	5.98e-04	GO:0002237	response to molecule of bacterial origin
3.88	6.70e-04	GO:0055065	metal ion homeostasis
3.10	7.26e-04	GO:0072358	cardiovascular system development
3.10	7.26e-04	GO:0072359	circulatory system development
26.72	7.68e-04	GO:0034374	low-density lipoprotein particle remodeling
2.92	8.03e-04	GO:0019725	cellular homeostasis
2.16	8.55e-04	GO:0002376	immune system process
2.47	8.66e-04	GO:0043933	macromolecular complex subunit organization
13.36	9.14e-04	GO:0071241	cellular response to inorganic substance
3.79	9.47e-04	GO:0001944	vasculature development
3.14	1.01e-03	GO:0055082	cellular chemical homeostasis
2.88	1.10e-03	GO:0006928	cellular component movement
6.61	1.13e-03	GO:0000302	response to reactive oxygen species
2.95	1.14e-03	GO:0008284	positive regulation of cell proliferation
3.74	1.19e-03	GO:0042493	response to drug
5.39	1.22e-03	GO:0032496	response to lipopolysaccharide
10.18	1.33e-03	GO:0034614	cellular response to reactive oxygen species
7.32	1.39e-03	GO:0033189	response to vitamin A
3.87	1.42e-03	GO:0001568	blood vessel development
2.46	1.51e-03	GO:0051128	regulation of cellular component organization
2.41	1.54e-03	GO:0040011	locomotion
1.74	1.58e-03	GO:0048522	positive regulation of cellular process
3.64	1.74e-03	GO:0030003	cellular cation homeostasis
3.43	2.32e-03	GO:0043434	response to peptide hormone stimulus
5.53	2.46e-03	GO:0033273	response to vitamin
3.10	3.74e-03	GO:0016477	cell migration
20.56	3.75e-03	GO:0010744	positive regulation of macrophage derived foam cell differentiation
8.91	3.86e-03	GO:0045766	positive regulation of angiogenesis
4.22	3.96e-03	GO:0008544	epidermis development
3.59	4.08e-03	GO:0040012	regulation of locomotion
3.76	4.24e-03	GO:0030334	regulation of cell migration
4.79	4.59e-03	GO:0030335	positive regulation of cell migration
4.79	4.59e-03	GO:2000147	positive regulation of cell motility
13.94	4.62e-03	GO:0071248	cellular response to metal ion
10.69	4.65e-03	GO:0003014	renal system process
3.71	5.01e-03	GO:2000145	regulation of cell motility
10.39	5.68e-03	GO:0044236	multicellular organismal metabolic process
19.09	5.74e-03	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
4.70	5.77e-03	GO:0050900	leukocyte migration
2.70	5.90e-03	GO:0050878	regulation of body fluid levels
30.54	6.05e-03	GO:0010873	positive regulation of cholesterol esterification
4.63	6.70e-03	GO:0040017	positive regulation of locomotion
3.32	6.80e-03	GO:0055080	cation homeostasis
10.11	6.90e-03	GO:0006953	acute-phase response
2.98	7.00e-03	GO:0006873	cellular ion homeostasis
1.70	8.16e-03	GO:0048519	negative regulation of biological process
17.82	8.48e-03	GO:0044058	regulation of digestive system process
3.93	9.50e-03	GO:0048514	blood vessel morphogenesis
4.49	9.62e-03	GO:0051272	positive regulation of cellular component movement
7.92	9.66e-03	GO:0051591	response to cAMP
12.34	1.01e-02	GO:0010743	regulation of macrophage derived foam cell differentiation
4.82	1.04e-02	GO:0006805	xenobiotic metabolic process
4.82	1.04e-02	GO:0071466	cellular response to xenobiotic stimulus
3.22	1.08e-02	GO:0051240	positive regulation of multicellular organismal process
4.79	1.12e-02	GO:0009410	response to xenobiotic stimulus
9.36	1.19e-02	GO:0072593	reactive oxygen species metabolic process
26.72	1.19e-02	GO:0003078	regulation of natriuresis
26.72	1.19e-02	GO:0044062	regulation of excretion
11.88	1.27e-02	GO:0044243	multicellular organismal catabolic process
7.64	1.28e-02	GO:0045834	positive regulation of lipid metabolic process
4.72	1.31e-02	GO:0019216	regulation of lipid metabolic process
4.05	1.40e-02	GO:0007584	response to nutrient
6.42	1.51e-02	GO:0002576	platelet degranulation
5.63	1.58e-02	GO:0045765	regulation of angiogenesis
2.44	1.58e-02	GO:0045595	regulation of cell differentiation
11.45	1.59e-02	GO:0032963	collagen metabolic process
3.98	1.68e-02	GO:0003013	circulatory system process
3.98	1.68e-02	GO:0008015	blood circulation
15.72	1.70e-02	GO:0010226	response to lithium ion
2.82	1.72e-02	GO:0048870	cell motility
2.82	1.72e-02	GO:0051674	localization of cell
5.57	1.73e-02	GO:0009266	response to temperature stimulus
5.57	1.73e-02	GO:0032103	positive regulation of response to external stimulus
3.38	1.74e-02	GO:0051270	regulation of cellular component movement
23.75	2.12e-02	GO:0010872	regulation of cholesterol esterification
7.13	2.16e-02	GO:0034599	cellular response to oxidative stress
5.40	2.28e-02	GO:0009612	response to mechanical stimulus
14.85	2.31e-02	GO:0042744	hydrogen peroxide catabolic process
10.69	2.44e-02	GO:0044259	multicellular organismal macromolecule metabolic process
2.75	2.48e-02	GO:0050801	ion homeostasis
2.37	2.69e-02	GO:0002682	regulation of immune system process
4.78	2.74e-02	GO:0051789	response to protein stimulus
3.13	2.78e-02	GO:0045597	positive regulation of cell differentiation
1.26	2.88e-02	GO:0065007	biological regulation
4.74	2.96e-02	GO:0031960	response to corticosteroid stimulus
6.79	3.11e-02	GO:0032526	response to retinoic acid
3.21	3.35e-02	GO:0034097	response to cytokine stimulus
21.38	3.48e-02	GO:0071285	cellular response to lithium ion
7.96	3.60e-02	GO:0019218	regulation of steroid metabolic process
40.08	3.91e-02	GO:0015793	glycerol transport
40.08	3.91e-02	GO:0030185	nitric oxide transport
40.08	3.91e-02	GO:0033860	regulation of NAD(P)H oxidase activity
40.08	3.91e-02	GO:0043589	skin morphogenesis
2.28	4.05e-02	GO:0006955	immune response
7.80	4.15e-02	GO:0050729	positive regulation of inflammatory response
9.72	4.34e-02	GO:0070555	response to interleukin-1
7.64	4.76e-02	GO:0034612	response to tumor necrosis factor
3.86	4.80e-02	GO:0006874	cellular calcium ion homeostasis
2.30	4.84e-02	GO:0051049	regulation of transport
6.38	4.92e-02	GO:0014075	response to amine stimulus

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
3.78	1.16e-45	GO:0005576	extracellular region
6.17	1.03e-42	GO:0005615	extracellular space
5.30	1.77e-42	GO:0044421	extracellular region part
4.59	1.88e-10	GO:0031012	extracellular matrix
5.08	1.01e-06	GO:0030141	stored secretory granule
4.02	2.29e-06	GO:0005578	proteinaceous extracellular matrix
26.72	5.68e-06	GO:0005833	hemoglobin complex
9.25	7.24e-05	GO:0031983	vesicle lumen
8.02	2.56e-04	GO:0000786	nucleosome
8.91	4.37e-04	GO:0034774	secretory granule lumen
10.69	5.27e-04	GO:0032994	protein-lipid complex
10.69	5.27e-04	GO:0034358	plasma lipoprotein particle
4.43	5.53e-04	GO:0005882	intermediate filament
8.55	6.02e-04	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
3.84	2.88e-03	GO:0045111	intermediate filament cytoskeleton
7.96	4.08e-03	GO:0031093	platelet alpha granule lumen
5.07	1.16e-02	GO:0032993	protein-DNA complex
11.14	1.19e-02	GO:0034364	high-density lipoprotein particle
6.57	1.46e-02	GO:0031091	platelet alpha granule
3.20	2.11e-02	GO:0005792	microsome
3.09	3.01e-02	GO:0042598	vesicular fraction
22.91	3.72e-02	GO:0005577	fibrinogen complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
3.08	7.88e-12	GO:0005102	receptor binding
6.20	1.86e-10	GO:0005506	iron ion binding
15.44	2.45e-10	GO:0019825	oxygen binding
8.26	2.85e-10	GO:0020037	heme binding
7.75	9.07e-10	GO:0046906	tetrapyrrole binding
3.25	1.51e-07	GO:0005198	structural molecule activity
5.60	7.95e-07	GO:0001664	G-protein-coupled receptor binding
5.24	8.77e-07	GO:0005125	cytokine activity
11.62	2.30e-06	GO:0008009	chemokine activity
10.48	6.64e-06	GO:0042379	chemokine receptor binding
24.67	1.49e-05	GO:0005344	oxygen transporter activity
3.52	2.04e-05	GO:0030246	carbohydrate binding
7.35	6.12e-05	GO:0004497	monooxygenase activity
6.48	7.11e-05	GO:0005179	hormone activity
1.17	1.42e-04	GO:0005488	binding
42.76	1.45e-04	GO:0046870	cadmium ion binding
5.78	2.49e-04	GO:0008201	heparin binding
9.72	3.14e-04	GO:0043498	cell surface binding
4.71	3.85e-04	GO:0008083	growth factor activity
13.36	9.86e-04	GO:0070330	aromatase activity
8.22	1.17e-03	GO:0005507	copper ion binding
1.29	1.53e-03	GO:0005515	protein binding
12.34	1.64e-03	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
4.16	1.66e-03	GO:0005126	cytokine receptor binding
4.37	2.07e-03	GO:0001871	pattern binding
4.37	2.07e-03	GO:0030247	polysaccharide binding
4.68	2.29e-03	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
6.02	4.17e-03	GO:0005201	extracellular matrix structural constituent
4.09	4.26e-03	GO:0009055	electron carrier activity
4.37	4.69e-03	GO:0005539	glycosaminoglycan binding
40.08	6.36e-03	GO:0015168	glycerol transmembrane transporter activity
40.08	6.36e-03	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
40.08	6.36e-03	GO:0034875	caffeine oxidase activity
6.02	1.23e-02	GO:0005200	structural constituent of cytoskeleton
2.57	2.57e-02	GO:0008289	lipid binding
4.50	4.18e-02	GO:0019838	growth factor binding