Motif ID: TBX4,5.p2

Z-value: 1.328


Transcription factors associated with TBX4,5.p2:

Gene SymbolEntrez IDGene Name
TBX4 9496 T-box 4
TBX5 6910 T-box 5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX5hg19_v1_chr12_-_114846191_114846246-0.222.3e-01Click!
TBX4hg19_v1_chr17_+_59533806_59533851-0.038.8e-01Click!


Activity profile for motif TBX4,5.p2.

activity profile for motif TBX4,5.p2


Sorted Z-values histogram for motif TBX4,5.p2

Sorted Z-values for motif TBX4,5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX4,5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_15016698 3.364 NM_004660
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr17_+_34431219 3.271 NM_002984
 CCL4
chemokine (C-C motif) ligand 4
chr1_-_156399183 2.975 NM_006365
 C1orf61
chromosome 1 open reading frame 61
chr17_+_34538464 2.761 NM_207007
NM_001001435
 CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chrY_+_15016018 2.315 NM_001122665
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr19_-_39108534 2.209 NM_001042600
NM_007181
 MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr1_+_26737306 2.198 LIN28A
lin-28 homolog A (C. elegans)
chr19_+_7828034 2.193 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
 CLEC4M








C-type lectin domain family 4, member M








chr19_+_7741934 2.181 NM_174918
 C19orf59
chromosome 19 open reading frame 59
chr11_+_60223281 2.012 NM_021950
NM_152866
 MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr6_-_130536417 2.008 NM_152552
 SAMD3
sterile alpha motif domain containing 3
chr5_-_131347518 1.934 NM_001205248
NM_001205251
NM_001205250
 ACSL6


acyl-CoA synthetase long-chain family member 6


chr1_-_202129731 1.905 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr12_-_6756597 1.897 ACRBP
acrosin binding protein
chr1_+_26737232 1.871 NM_024674
 LIN28A
lin-28 homolog A (C. elegans)
chr5_+_54320083 1.831 NM_002104
 GZMK
granzyme K (granzyme 3; tryptase II)
chr6_+_31543340 1.821 NM_000594
 TNF
tumor necrosis factor
chr5_-_131347249 1.791 NM_001009185
NM_001205247
NM_015256
 ACSL6


acyl-CoA synthetase long-chain family member 6


chr12_+_10183275 1.784 NM_207345
 CLEC9A
C-type lectin domain family 9, member A
chr9_+_137772653 1.779 NM_004108
NM_015837
 FCN2

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
165.57 1.98e-02 GO:0060544 regulation of necroptosis
165.57 1.98e-02 GO:0060545 positive regulation of necroptosis
165.57 1.98e-02 GO:0060553 induction of necroptosis
165.57 1.98e-02 GO:0060555 induction of necroptosis by extracellular signals
124.18 3.94e-02 GO:0010940 positive regulation of necrotic cell death
124.18 3.94e-02 GO:0070265 necrotic cell death
32.41 4.22e-02 GO:0043525 positive regulation of neuron apoptosis
17.44 3.20e-02 GO:0008037 cell recognition
6.55 3.54e-02 GO:0006954 inflammatory response
4.76 8.84e-04 GO:0006955 immune response
3.58 2.03e-03 GO:0002376 immune system process
2.31 3.18e-04 GO:0023052 signaling
2.22 5.72e-03 GO:0007165 signal transduction
1.95 2.91e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
3.68 1.31e-02 GO:0005615 extracellular space
2.36 2.76e-02 GO:0005576 extracellular region
1.82 3.11e-02 GO:0005886 plasma membrane
1.79 4.00e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
24.85 1.67e-03 GO:0003823 antigen binding
8.29 6.97e-03 GO:0005126 cytokine receptor binding
7.70 1.05e-02 GO:0005125 cytokine activity