Motif ID: TFAP2B.p2

Z-value: 1.487


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v1_chr6_+_50786438_50786632-0.281.2e-01Click!


Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_160114318 3.255 NM_000636
NM_001024465
NM_001024466
 SOD2


superoxide dismutase 2, mitochondrial


chr6_-_160114186 3.124 SOD2
superoxide dismutase 2, mitochondrial
chr20_-_62130390 2.866 NM_001958
 EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr8_-_124553448 2.600 NM_001242463
NM_058229
 FBXO32

F-box protein 32

chr8_-_141645603 2.410 NM_001164623
NM_012154
 EIF2C2

eukaryotic translation initiation factor 2C, 2

chr5_+_7396030 2.264 NM_020546
 ADCY2
adenylate cyclase 2 (brain)
chr17_+_78234626 2.260 NM_020914
NM_020954
 RNF213

ring finger protein 213

chr2_+_241508103 2.219 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr3_-_38691118 2.177 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
 SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr1_+_236849753 2.135 NM_001103
 ACTN2
actinin, alpha 2
chr2_+_241507928 2.127 NM_018226
 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr20_+_57466509 2.114 GNAS
GNAS complex locus
chr2_-_240322620 2.108 NM_006037
 HDAC4
histone deacetylase 4
chr2_-_240322692 2.096 HDAC4
histone deacetylase 4
chr22_-_50699938 2.074 NM_002969
 MAPK12
mitogen-activated protein kinase 12
chr20_+_57466248 2.072 NM_000516
NM_001077488
NM_001077489
NM_080426
 GNAS



GNAS complex locus



chr6_+_157099262 2.047 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr1_-_33336289 2.009 NM_001171940
NM_153756
 FNDC5

fibronectin type III domain containing 5

chr5_-_78809658 2.003 NM_004272
 HOMER1
homer homolog 1 (Drosophila)
chr7_-_150946031 1.968 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
10.22 7.33e-04 GO:0042692 muscle cell differentiation
7.88 1.35e-03 GO:0007517 muscle organ development
7.49 7.46e-03 GO:0003012 muscle system process
7.46 4.34e-05 GO:0061061 muscle structure development
7.13 3.70e-02 GO:0006936 muscle contraction
3.12 2.97e-02 GO:0048468 cell development
2.29 2.22e-02 GO:0030154 cell differentiation
2.23 3.55e-02 GO:0048869 cellular developmental process
2.20 4.62e-03 GO:0071842 cellular component organization at cellular level
2.12 9.82e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.85 1.97e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
21.17 4.67e-04 GO:0030018 Z disc
16.76 1.52e-03 GO:0031674 I band
13.87 3.21e-07 GO:0030016 myofibril
13.14 2.12e-05 GO:0030017 sarcomere
13.09 5.70e-07 GO:0043292 contractile fiber
12.82 4.23e-06 GO:0044449 contractile fiber part
5.07 9.19e-03 GO:0015629 actin cytoskeleton
2.69 6.68e-04 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
107.23 1.69e-02 GO:0046975 histone methyltransferase activity (H3-K36 specific)
14.97 2.08e-02 GO:0008307 structural constituent of muscle
6.16 7.59e-05 GO:0003779 actin binding
5.01 1.43e-05 GO:0008092 cytoskeletal protein binding
1.72 2.50e-02 GO:0046872 metal ion binding
1.70 3.19e-02 GO:0043169 cation binding
1.69 3.37e-02 GO:0043167 ion binding