Motif ID: UAUUGCU

Z-value: 1.910


Mature miRNA associated with seed UAUUGCU:

NamemiRBase Accession
hsa-miR-137 MIMAT0000429



Activity profile for motif UAUUGCU.

activity profile for motif UAUUGCU


Sorted Z-values histogram for motif UAUUGCU

Sorted Z-values for motif UAUUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAUUGCU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_236849753 8.267 NM_001103
 ACTN2
actinin, alpha 2
chr5_-_149669400 6.726 NM_015981
NM_171825
 CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr19_-_2721337 6.584 NM_145173
 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr2_+_155555092 5.929 NM_002239
 KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr5_+_7396030 5.834 NM_020546
 ADCY2
adenylate cyclase 2 (brain)
chr8_-_22014263 5.478 NM_139278
 LGI3
leucine-rich repeat LGI family, member 3
chr8_-_24814028 5.352 NM_006158
 NEFL
neurofilament, light polypeptide
chr13_+_23755059 5.282 NM_000231
 SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr9_-_101470836 5.245 NM_005458
 GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_-_84419108 5.215 NM_001242793
NM_001242794
NM_014841
 SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr20_+_24449834 5.177 NM_024893
 SYNDIG1
synapse differentiation inducing 1
chr11_-_18813127 5.047 NM_001039970
NM_006906
NM_032781
 PTPN5


protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)


chr1_-_33338081 5.032 NM_001171941
 FNDC5
fibronectin type III domain containing 5
chr11_-_790103 4.972 NM_016564
 CEND1
cell cycle exit and neuronal differentiation 1
chr19_-_11591439 4.952 NM_001420
NM_032281
 ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr6_-_84418705 4.928 NM_001242792
 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr22_+_42372763 4.751 NM_019106
NM_145733
 SEPT3

septin 3

chr7_-_44105162 4.735 NM_000290
 PGAM2
phosphoglycerate mutase 2 (muscle)
chr2_-_213403280 4.707 NM_001042599
NM_005235
 ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr20_-_55841671 4.629 NM_001719
 BMP7
bone morphogenetic protein 7

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
Enrichment   P-value GO Accession GO Term
11.33 7.68e-05 GO:0007612 learning
8.82 2.39e-06 GO:0006836 neurotransmitter transport
7.12 3.82e-04 GO:0007611 learning or memory
6.51 9.42e-04 GO:0050890 cognition
5.73 4.24e-13 GO:0007268 synaptic transmission
5.57 4.35e-14 GO:0019226 transmission of nerve impulse
5.57 4.35e-14 GO:0035637 multicellular organismal signaling
5.57 3.24e-02 GO:0050804 regulation of synaptic transmission
5.45 1.43e-02 GO:0006814 sodium ion transport
5.01 1.20e-02 GO:0006813 potassium ion transport
4.09 9.55e-04 GO:0007610 behavior
3.74 3.92e-09 GO:0007267 cell-cell signaling
3.63 8.97e-03 GO:0015672 monovalent inorganic cation transport
3.59 1.05e-02 GO:0044057 regulation of system process
3.43 5.12e-04 GO:0030001 metal ion transport
3.12 6.97e-08 GO:0007154 cell communication
3.05 2.09e-03 GO:0006812 cation transport
2.94 6.30e-03 GO:0048666 neuron development
2.68 5.67e-04 GO:0006811 ion transport
2.46 6.64e-06 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
Enrichment   P-value GO Accession GO Term
69.21 4.18e-02 GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
21.30 5.55e-03 GO:0008328 ionotropic glutamate receptor complex
13.85 3.47e-02 GO:0044304 main axon
11.08 1.10e-04 GO:0044309 neuron spine
10.10 1.09e-03 GO:0043197 dendritic spine
9.11 4.16e-02 GO:0030018 Z disc
8.76 4.07e-05 GO:0014069 postsynaptic density
7.29 2.79e-03 GO:0033267 axon part
6.99 3.42e-04 GO:0019717 synaptosome
6.67 1.65e-05 GO:0034703 cation channel complex
6.07 5.63e-15 GO:0045202 synapse
6.01 1.46e-10 GO:0044456 synapse part
5.53 2.04e-05 GO:0030425 dendrite
5.15 2.11e-03 GO:0045211 postsynaptic membrane
5.06 3.86e-10 GO:0043005 neuron projection
5.00 7.62e-05 GO:0034702 ion channel complex
4.90 4.79e-02 GO:0044449 contractile fiber part
4.48 7.69e-03 GO:0043025 neuronal cell body
4.35 1.00e-02 GO:0044297 cell body
4.33 1.06e-02 GO:0030424 axon

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
69.21 4.73e-02 GO:0070080 titin Z domain binding
29.67 2.28e-02 GO:0031432 titin binding
23.07 4.39e-03 GO:0005251 delayed rectifier potassium channel activity
17.31 2.54e-05 GO:0008066 glutamate receptor activity
15.38 2.53e-02 GO:0005234 extracellular-glutamate-gated ion channel activity
15.38 2.53e-02 GO:0005328 neurotransmitter:sodium symporter activity
6.83 4.33e-06 GO:0022843 voltage-gated cation channel activity
6.30 2.82e-02 GO:0005262 calcium channel activity
5.19 1.35e-04 GO:0005244 voltage-gated ion channel activity
5.19 1.35e-04 GO:0022832 voltage-gated channel activity
4.60 3.75e-06 GO:0022836 gated channel activity
4.46 7.20e-05 GO:0005261 cation channel activity
4.00 8.88e-06 GO:0005216 ion channel activity
3.94 1.17e-05 GO:0022838 substrate-specific channel activity
3.82 2.00e-05 GO:0015267 channel activity
3.81 2.09e-05 GO:0022803 passive transmembrane transporter activity
3.10 2.31e-04 GO:0008324 cation transmembrane transporter activity
2.85 9.74e-05 GO:0015075 ion transmembrane transporter activity
2.52 7.33e-04 GO:0022891 substrate-specific transmembrane transporter activity
2.34 3.24e-03 GO:0022857 transmembrane transporter activity