Motif ID: UCACAGU

Z-value: 1.144


Mature miRNA associated with seed UCACAGU:

NamemiRBase Accession
hsa-miR-27a MIMAT0000084
hsa-miR-27b MIMAT0000419



Activity profile for motif UCACAGU.

activity profile for motif UCACAGU


Sorted Z-values histogram for motif UCACAGU

Sorted Z-values for motif UCACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_50344255 3.832 NM_001220765
NM_001220766
NM_001220767
NM_001220768
NM_001220769
NM_001220770
NM_001220771
NM_001220772
NM_001220773
NM_001220774
NM_001220775
NM_001220776
NM_006060
IKZF1












IKAROS family zinc finger 1 (Ikaros)












chr7_-_27183225 2.837 NM_019102
HOXA5
homeobox A5
chr6_+_391738 2.747 NM_001195286
NM_002460
IRF4

interferon regulatory factor 4

chr19_+_45971249 2.591 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr2_+_204801453 2.563 NM_012092
ICOS
inducible T-cell co-stimulator
chr6_+_50786438 2.295 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr7_-_27213873 2.244 NM_018951
HOXA10
homeobox A10
chr2_-_235405692 2.212 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr1_-_108507474 2.088 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr6_-_24911194 2.088 NM_014722
FAM65B
family with sequence similarity 65, member B
chr1_-_200992824 2.086 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr11_+_121322848 2.062 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_-_47655723 2.050 NM_005764
PDZK1IP1
PDZK1 interacting protein 1
chr2_+_204571197 2.012 NM_001243077
NM_001243078
NM_006139
CD28


CD28 molecule


chr2_-_109605668 1.990 NM_022336
EDAR
ectodysplasin A receptor
chr1_-_108231122 1.966 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr14_+_92788924 1.916 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92790151 1.890 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr9_-_130712866 1.889 NM_203305
FAM102A
family with sequence similarity 102, member A
chr14_+_92789536 1.847 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_+_152880024 1.822 NM_002886
RAP2B
RAP2B, member of RAS oncogene family
chr17_+_30813928 1.741 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_-_36391448 1.702 NM_139239
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr19_+_45251933 1.679 NM_005178
BCL3
B-cell CLL/lymphoma 3
chr15_-_74726258 1.669 NM_001146029
NM_003612
SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

chr5_+_170210711 1.656 NM_014211
GABRP
gamma-aminobutyric acid (GABA) A receptor, pi
chr11_+_14665268 1.636 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr6_+_126111782 1.612 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr5_-_1524022 1.610 NM_024830
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr2_+_192542860 1.568 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr15_+_81071708 1.552 NM_018689
KIAA1199
KIAA1199
chr5_+_112312392 1.547 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr15_-_74726000 1.533 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr4_-_164534656 1.499 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr17_-_46692300 1.493 NM_024016
HOXB8
homeobox B8
chr3_-_129325175 1.474 NM_015103
PLXND1
plexin D1
chr7_+_26403944 1.468 NM_001199838
SNX10
sorting nexin 10
chr7_+_26331493 1.459 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr1_+_206680863 1.456 NM_182663
NM_182664
RASSF5

Ras association (RalGDS/AF-6) domain family member 5

chr9_-_130742803 1.433 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr17_-_53499055 1.426 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr5_-_111091947 1.423 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr17_-_73401788 1.403 NM_002086
NM_203506
GRB2

growth factor receptor-bound protein 2

chr9_+_129622935 1.378 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr15_+_81293286 1.375 NM_022566
MESDC1
mesoderm development candidate 1
chr4_-_42154894 1.373 NM_001159547
NM_207406
BEND4

BEN domain containing 4

chr7_+_26400503 1.371 NM_001199837
SNX10
sorting nexin 10
chr13_-_48987652 1.358 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr1_+_29213569 1.328 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr14_+_52734430 1.325 NM_000953
PTGDR
prostaglandin D2 receptor (DP)
chr12_-_92539614 1.319 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr9_+_127020462 1.310 NM_001166168
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr12_+_54422193 1.291 NM_004503
HOXC6
homeobox C6
chr10_+_112257624 1.251 NM_004419
DUSP5
dual specificity phosphatase 5
chr6_+_126102278 1.251 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr6_+_114178516 1.250 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr9_+_127019782 1.223 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr1_+_9711781 1.211 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr5_-_171615320 1.199 NM_005990
STK10
serine/threonine kinase 10
chr11_+_120081669 1.192 NM_178507
OAF
OAF homolog (Drosophila)
chr4_-_165304406 1.181 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr16_-_89007605 1.159 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr8_-_127570710 1.149 NM_174911
FAM84B
family with sequence similarity 84, member B
chr19_-_43969723 1.148 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr7_+_2557496 1.148 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_+_127054567 1.143 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr20_-_14318200 1.129 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr12_+_65004191 1.125 NM_178169
RASSF3
Ras association (RalGDS/AF-6) domain family member 3
chr13_-_74707913 1.120 NM_007249
KLF12
Kruppel-like factor 12
chr20_-_41818464 1.114 NM_007050
NM_133170
PTPRT

protein tyrosine phosphatase, receptor type, T

chrX_+_49832214 1.111 NM_000084
CLCN5
chloride channel 5
chr20_-_62610990 1.106 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr17_+_15848230 1.106 NM_000676
ADORA2B
adenosine A2b receptor
chr6_+_126240369 1.103 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr12_+_32112286 1.094 NM_018169
C12orf35
chromosome 12 open reading frame 35
chr5_-_157002739 1.090 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr18_+_55102777 1.081 NM_004852
ONECUT2
one cut homeobox 2
chr5_+_52284903 1.081 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr5_-_176981537 1.071 NM_001190946
FAM193B
family with sequence similarity 193, member B
chr21_+_33245304 1.070 NM_014586
HUNK
hormonally up-regulated Neu-associated kinase
chr11_-_128712340 1.058 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr4_+_56815036 1.042 NM_025009
CEP135
centrosomal protein 135kDa
chr7_+_2552162 1.032 NM_001166355
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_+_127054246 1.028 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr8_-_37756971 1.028 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr13_-_49018802 1.024 NM_005767
LPAR6
lysophosphatidic acid receptor 6
chr15_-_79383080 1.022 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr16_+_23847271 1.018 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr22_-_32026783 1.017 NM_014338
PISD
phosphatidylserine decarboxylase
chr12_+_15699277 1.011 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr2_-_39347562 1.004 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr3_-_39195101 1.002 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr19_-_13617037 0.998 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr15_-_51914770 0.975 NM_001174116
NM_001174117
NM_015263
DMXL2


Dmx-like 2


chr1_+_213123853 0.974 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr17_+_38474472 0.968 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr9_-_134151905 0.964 NM_033387
FAM78A
family with sequence similarity 78, member A
chr9_-_136857285 0.956 NM_001134398
NM_003371
VAV2

vav 2 guanine nucleotide exchange factor

chr13_-_49001042 0.955 NM_001162497
LPAR6
lysophosphatidic acid receptor 6
chr6_-_42419782 0.951 NM_033502
TRERF1
transcriptional regulating factor 1
chr12_-_77459198 0.950 NM_203394
E2F7
E2F transcription factor 7
chr7_+_45039777 0.946 NM_001167934
NM_001167935
NM_031443
CCM2


cerebral cavernous malformation 2


chr6_+_11538486 0.933 NM_001100829
TMEM170B
transmembrane protein 170B
chr7_+_7222142 0.931 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr6_+_41606193 0.929 NM_005586
MDFI
MyoD family inhibitor
chrX_+_17393537 0.920 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_+_28585959 0.918 NM_031459
SESN2
sestrin 2
chr10_+_8096633 0.909 NM_001002295
NM_002051
GATA3

GATA binding protein 3

chr14_+_103243813 0.902 NM_001199427
NM_003300
NM_145725
NM_145726
TRAF3



TNF receptor-associated factor 3



chr8_-_60031545 0.898 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr4_+_26862312 0.889 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2


chr2_-_201936389 0.888 NM_173822
FAM126B
family with sequence similarity 126, member B
chr20_+_3776385 0.880 NM_004358
NM_021872
NM_021873
CDC25B


cell division cycle 25 homolog B (S. pombe)


chr3_-_32023237 0.851 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr8_-_103136486 0.849 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
NCALD





neurocalcin delta





chr21_-_43373938 0.846 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr14_-_78083109 0.845 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr11_-_128737132 0.841 NM_153764
NM_153765
NM_153766
NM_153767
KCNJ1



potassium inwardly-rectifying channel, subfamily J, member 1



chr12_-_25403824 0.837 NM_004985
NM_033360
KRAS

v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

chr15_-_79298001 0.836 NM_153815
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr10_+_11047253 0.834 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr12_+_53773924 0.833 NM_001251825
NM_138473
SP1

Sp1 transcription factor

chr5_-_83016850 0.833 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr17_-_58603492 0.832 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr8_-_22550708 0.831 NM_004430
EGR3
early growth response 3
chr12_+_99038918 0.829 NM_001160
NM_013229
NM_181861
NM_181868
NM_181869
APAF1




apoptotic peptidase activating factor 1




chr16_-_70472920 0.828 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr1_+_110168048 0.823 NM_203404
AMPD2
adenosine monophosphate deaminase 2
chr17_-_56084656 0.819 NM_001078166
NM_006924
SRSF1

serine/arginine-rich splicing factor 1

chr12_+_53774422 0.818 NM_003109
SP1
Sp1 transcription factor
chr16_-_89043215 0.816 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr12_-_106641675 0.814 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr1_+_228194722 0.812 NM_033131
WNT3A
wingless-type MMTV integration site family, member 3A
chr4_+_38665587 0.802 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr12_-_22487566 0.795 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr3_-_128206704 0.790 NM_001145662
GATA2
GATA binding protein 2
chr1_+_101361589 0.790 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr8_+_80523048 0.788 NM_001199214
NM_007029
STMN2

stathmin-like 2

chr2_+_163200582 0.779 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr8_-_22550057 0.774 NM_001199881
EGR3
early growth response 3
chr1_+_244216506 0.773 NM_006352
ZNF238
zinc finger protein 238
chr4_+_77870864 0.769 NM_018243
SEPT11
septin 11
chr1_+_199996729 0.766 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr11_+_122526339 0.766 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr7_-_139876718 0.764 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr2_+_113403433 0.753 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr16_+_577833 0.753 NM_005632
SOLH
small optic lobes homolog (Drosophila)
chr17_-_28562953 0.752 NM_001045
SLC6A4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr19_+_11200037 0.752 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr2_+_85132762 0.750 NM_021103
TMSB10
thymosin beta 10
chr1_-_161039745 0.749 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr19_-_47734215 0.744 NM_014417
BBC3
BCL2 binding component 3
chr12_-_120703549 0.741 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr11_-_102826433 0.739 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chrX_+_49687212 0.737 NM_001127898
NM_001127899
CLCN5

chloride channel 5

chr10_-_60027630 0.736 NM_152230
IPMK
inositol polyphosphate multikinase
chr3_-_128212027 0.731 NM_032638
GATA2
GATA binding protein 2
chr10_+_11206928 0.726 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr11_-_88796815 0.724 NM_000842
GRM5
glutamate receptor, metabotropic 5
chr1_-_93646245 0.720 NM_001167830
NM_016040
TMED5

transmembrane emp24 protein transport domain containing 5

chr16_-_48644087 0.719 NM_153029
N4BP1
NEDD4 binding protein 1
chr17_+_25621105 0.719 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr17_-_40075238 0.718 NM_001096
NM_198830
ACLY

ATP citrate lyase

chr12_+_105501448 0.717 NM_015275
KIAA1033
KIAA1033
chr6_-_149806116 0.717 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr1_-_39338976 0.717 NM_012333
MYCBP
c-myc binding protein
chr8_+_125486949 0.715 NM_007218
RNF139
ring finger protein 139
chr16_-_11680146 0.712 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr17_+_37026111 0.712 NM_006148
LASP1
LIM and SH3 protein 1
chr18_-_74207145 0.711 NM_014643
ZNF516
zinc finger protein 516
chr5_+_14664764 0.709 NM_138348
FAM105B
family with sequence similarity 105, member B
chr16_-_68482373 0.707 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr18_-_3011944 0.704 NM_014646
LPIN2
lipin 2
chr2_+_74273449 0.703 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr12_-_65153189 0.697 NM_002076
GNS
glucosamine (N-acetyl)-6-sulfatase
chr1_+_23037329 0.695 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr1_+_206730456 0.693 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr14_+_56584854 0.692 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr13_+_24734788 0.690 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr8_-_22549901 0.688 NM_001199880
EGR3
early growth response 3
chr8_-_74791098 0.688 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr7_-_92465929 0.687 NM_001145306
CDK6
cyclin-dependent kinase 6
chrX_-_110654373 0.684 NM_000555
DCX
doublecortin
chr14_-_39901619 0.683 NM_203301
FBXO33
F-box protein 33
chr7_+_30174343 0.682 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr4_+_174089889 0.681 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr20_-_20693122 0.675 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr7_+_6144504 0.675 NM_032172
USP42
ubiquitin specific peptidase 42
chr16_-_11680756 0.672 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr12_+_54410641 0.671 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr12_+_15475190 0.656 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr5_+_82767492 0.655 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr8_-_103137134 0.650 NM_001040630
NCALD
neurocalcin delta
chr1_+_207070787 0.649 NM_001185156
NM_001185157
NM_001185158
NM_006850
IL24



interleukin 24



chr17_+_38498270 0.648 NM_001024809
RARA
retinoic acid receptor, alpha
chr18_+_13218777 0.644 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr17_+_38278789 0.643 NM_001012241
MSL1
male-specific lethal 1 homolog (Drosophila)
chr9_+_130830447 0.643 NM_001006641
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr18_+_13620866 0.643 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr9_+_137533643 0.641 NM_000093
COL5A1
collagen, type V, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.27 2.38e-03 GO:0007275 multicellular organismal development
241.26 8.23e-03 GO:0045082 positive regulation of interleukin-10 biosynthetic process
2.07 1.57e-02 GO:0032502 developmental process
2.15 1.69e-02 GO:0007165 signal transduction
2.44 1.93e-02 GO:0048522 positive regulation of cellular process
7.42 2.04e-02 GO:0002694 regulation of leukocyte activation
2.29 2.16e-02 GO:0048731 system development
160.84 2.46e-02 GO:0045074 regulation of interleukin-10 biosynthetic process
7.14 2.60e-02 GO:0050865 regulation of cell activation
1.80 3.20e-02 GO:0032501 multicellular organismal process
2.03 3.52e-02 GO:0023052 signaling
1.62 3.75e-02 GO:0050794 regulation of cellular process
2.90 4.04e-02 GO:0009653 anatomical structure morphogenesis
2.14 4.28e-02 GO:0048856 anatomical structure development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.13 4.09e-02 GO:0001071 nucleic acid binding transcription factor activity
3.13 4.09e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
6.25 4.23e-02 GO:0019900 kinase binding