Motif ID: UCCAGUU

Z-value: 2.052


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145 MIMAT0000437



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_121103670 4.457 NM_002193
 INHBB
inhibin, beta B
chr1_+_86046434 4.429 NM_001554
 CYR61
cysteine-rich, angiogenic inducer, 61
chr21_-_39870303 4.191 NM_001136155
NM_182918
 ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr7_+_116139619 3.986 NM_001206747
NM_001233
NM_198212
 CAV2


caveolin 2


chr8_-_12990731 3.682 NM_006094
 DLC1
deleted in liver cancer 1
chr8_-_12973752 3.645 NM_001164271
 DLC1
deleted in liver cancer 1
chr11_-_86666211 3.555 NM_012193
 FZD4
frizzled family receptor 4
chr8_-_119964059 3.540 NM_002546
 TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr7_+_116140097 3.455 NM_001206748
 CAV2
caveolin 2
chr7_-_131241321 3.390 NM_001018111
NM_005397
 PODXL

podocalyxin-like

chr9_+_112403067 3.316 NM_001037293
 PALM2
paralemmin 2
chr5_-_121412805 3.288 NM_001178102
 LOX
lysyl oxidase
chr9_-_112213663 3.034 NM_001145369
NM_001145370
 PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr9_-_112191105 3.023 NM_001145371
NM_001145372
 PTPN3

protein tyrosine phosphatase, non-receptor type 3

chrX_-_99891690 3.022 NM_003270
 TSPAN6
tetraspanin 6
chr1_-_147232684 3.007 NM_181703
 GJA5
gap junction protein, alpha 5, 40kDa
chr1_-_147245483 2.983 NM_005266
 GJA5
gap junction protein, alpha 5, 40kDa
chr6_+_151646634 2.945 NM_144497
 AKAP12
A kinase (PRKA) anchor protein 12
chr9_-_14398981 2.901 NM_001190738
 NFIB
nuclear factor I/B
chr21_-_28339405 2.818 NM_007038
 ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
Enrichment   P-value GO Accession GO Term
59.26 8.58e-03 GO:0007016 cytoskeletal anchoring at plasma membrane
44.45 2.22e-02 GO:0048009 insulin-like growth factor receptor signaling pathway
5.96 1.22e-02 GO:0051270 regulation of cellular component movement
5.89 3.93e-02 GO:0030334 regulation of cell migration
5.81 4.29e-02 GO:2000145 regulation of cell motility
4.29 3.02e-02 GO:0009967 positive regulation of signal transduction
4.09 4.61e-02 GO:0010647 positive regulation of cell communication
4.07 4.87e-02 GO:0023056 positive regulation of signaling
3.45 1.57e-02 GO:0040011 locomotion
3.23 2.24e-04 GO:0009966 regulation of signal transduction
2.93 6.80e-04 GO:0023051 regulation of signaling
2.93 2.13e-03 GO:0009653 anatomical structure morphogenesis
2.55 8.02e-03 GO:0048583 regulation of response to stimulus
2.43 4.12e-02 GO:0007166 cell surface receptor linked signaling pathway
2.29 9.56e-03 GO:0048522 positive regulation of cellular process
2.28 2.24e-02 GO:0042221 response to chemical stimulus
2.27 3.54e-04 GO:0048856 anatomical structure development
2.26 1.39e-05 GO:0032502 developmental process
2.19 3.49e-04 GO:0007275 multicellular organismal development
2.11 2.14e-02 GO:0048731 system development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
10.59 1.29e-02 GO:0030027 lamellipodium
7.22 2.18e-02 GO:0045121 membrane raft
6.96 7.83e-03 GO:0031252 cell leading edge
2.45 4.79e-04 GO:0044459 plasma membrane part
2.00 1.07e-04 GO:0005886 plasma membrane
1.97 1.61e-04 GO:0071944 cell periphery
1.46 1.41e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
118.52 1.25e-02 GO:0034186 apolipoprotein A-I binding
88.89 2.48e-02 GO:0005010 insulin-like growth factor receptor activity
21.34 4.81e-02 GO:0050840 extracellular matrix binding
5.11 8.91e-03 GO:0003779 actin binding
3.81 1.91e-02 GO:0008092 cytoskeletal protein binding
1.60 2.31e-04 GO:0005515 protein binding