Motif ID: UGUGCUU

Z-value: 3.288


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
hsa-miR-218 MIMAT0000275



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_19322763 15.433 NM_004386
 NCAN
neurocan
chr11_-_35441501 14.795 NM_001195728
NM_001252652
 SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr11_-_45307617 14.617 NM_001247987
NM_020826
 SYT13

synaptotagmin XIII

chr11_+_62475113 14.236 NM_012202
 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr5_-_176057324 13.556 NM_001001502
NM_003085
 SNCB

synuclein, beta

chr11_-_35441099 13.409 NM_004171
 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_-_6383572 13.287 NM_181876
 PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr1_+_110693131 12.932 NM_001010898
 SLC6A17
solute carrier family 6, member 17
chr4_-_6557404 12.400 NM_001206995
 PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr4_-_6422844 12.310 NM_001206996
 PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr9_-_93405066 11.790 NM_017594
 DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr4_-_6565326 11.790 NM_001206994
 PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr5_-_160975124 10.966 NM_000813
NM_021911
 GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr2_-_2334887 10.961 NM_015025
 MYT1L
myelin transcription factor 1-like
chr3_-_179754516 10.169 NM_016559
 PEX5L
peroxisomal biogenesis factor 5-like
chr5_+_139175385 10.006 NM_032289
 PSD2
pleckstrin and Sec7 domain containing 2
chrX_+_12156584 9.840 NM_014728
 FRMPD4
FERM and PDZ domain containing 4
chr3_-_192445344 9.719 NM_004113
 FGF12
fibroblast growth factor 12
chr19_-_2721337 9.516 NM_145173
 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr6_+_118228688 9.515 NM_001029858
 SLC35F1
solute carrier family 35, member F1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 46 entries
Enrichment   P-value GO Accession GO Term
20.75 2.97e-02 GO:0048488 synaptic vesicle endocytosis
10.70 1.83e-02 GO:0048489 synaptic vesicle transport
7.83 3.13e-06 GO:0006836 neurotransmitter transport
5.87 4.83e-17 GO:0007268 synaptic transmission
5.61 1.09e-17 GO:0019226 transmission of nerve impulse
5.61 1.09e-17 GO:0035637 multicellular organismal signaling
5.26 5.22e-04 GO:0006813 potassium ion transport
4.50 7.64e-03 GO:0030900 forebrain development
4.24 1.45e-15 GO:0007267 cell-cell signaling
3.94 7.99e-07 GO:0048812 neuron projection morphogenesis
3.86 5.16e-06 GO:0007409 axonogenesis
3.72 1.08e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
3.72 5.78e-04 GO:0007411 axon guidance
3.70 1.69e-06 GO:0031175 neuron projection development
3.64 1.69e-09 GO:0030182 neuron differentiation
3.63 1.86e-07 GO:0048666 neuron development
3.59 3.25e-06 GO:0007417 central nervous system development
3.54 2.02e-11 GO:0048699 generation of neurons
3.51 1.05e-05 GO:0048858 cell projection morphogenesis
3.48 1.26e-05 GO:0032990 cell part morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 38 entries
Enrichment   P-value GO Accession GO Term
24.45 3.42e-02 GO:0030673 axolemma
17.12 1.69e-04 GO:0044304 main axon
13.43 3.56e-02 GO:0032589 neuron projection membrane
12.34 3.95e-05 GO:0042734 presynaptic membrane
11.41 1.39e-05 GO:0030672 synaptic vesicle membrane
8.26 1.64e-05 GO:0033267 axon part
7.87 7.34e-06 GO:0008021 synaptic vesicle
7.33 3.17e-19 GO:0044456 synapse part
7.13 3.55e-02 GO:0043197 dendritic spine
6.92 3.17e-05 GO:0019717 synaptosome
6.85 4.46e-02 GO:0044309 neuron spine
6.62 7.25e-22 GO:0045202 synapse
6.50 1.91e-03 GO:0014069 postsynaptic density
6.24 2.44e-02 GO:0031256 leading edge membrane
6.04 3.48e-03 GO:0030665 clathrin coated vesicle membrane
5.91 4.21e-03 GO:0008076 voltage-gated potassium channel complex
5.91 4.21e-03 GO:0034705 potassium channel complex
5.51 2.73e-06 GO:0030424 axon
5.50 1.46e-04 GO:0034703 cation channel complex
5.40 6.80e-05 GO:0045211 postsynaptic membrane

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
5.82 2.37e-03 GO:0005249 voltage-gated potassium channel activity
5.63 5.80e-05 GO:0022843 voltage-gated cation channel activity
5.44 6.24e-04 GO:0005267 potassium channel activity
4.58 3.10e-04 GO:0005244 voltage-gated ion channel activity
4.58 3.10e-04 GO:0022832 voltage-gated channel activity
4.57 1.98e-02 GO:0015276 ligand-gated ion channel activity
4.57 1.98e-02 GO:0022834 ligand-gated channel activity
4.55 2.01e-07 GO:0022836 gated channel activity
4.11 6.29e-05 GO:0005261 cation channel activity
4.05 2.32e-07 GO:0005216 ion channel activity
4.01 1.39e-07 GO:0015267 channel activity
4.00 1.47e-07 GO:0022803 passive transmembrane transporter activity
3.98 3.27e-07 GO:0022838 substrate-specific channel activity
2.75 2.81e-05 GO:0015075 ion transmembrane transporter activity
2.66 2.62e-03 GO:0008324 cation transmembrane transporter activity
2.43 3.49e-04 GO:0022891 substrate-specific transmembrane transporter activity
2.38 2.75e-04 GO:0022857 transmembrane transporter activity
2.11 1.03e-03 GO:0005215 transporter activity
2.09 9.36e-03 GO:0022892 substrate-specific transporter activity