Motif ID: YY1.p2

Z-value: 4.717


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
YY1 7528 YY1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
YY1hg19_v1_chr14_+_100705432_1007055800.125.0e-01Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_121824015 8.018


chr8_-_121823696 7.945 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr12_+_6647339 7.908 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr1_+_148644010 7.091 NM_001144032
PPIAL4E
peptidylprolyl isomerase A (cyclophilin A)-like 4E
chr5_-_149669187 6.611 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr19_-_47615802 6.264


chr17_+_65040651 6.057 NM_000727
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr17_+_26369935 6.022 NLK
nemo-like kinase
chr12_+_81101407 5.822 NM_002469
MYF6
myogenic factor 6 (herculin)
chr22_-_36013303 5.447 NM_005368
NM_203378
MB

myoglobin

chr17_-_62050200 5.372 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr19_-_55895602 5.365 NM_001190764
TMEM238
transmembrane protein 238
chr5_-_149669400 5.288 NM_015981
NM_171825
CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr1_-_200377488 4.704 ZNF281
zinc finger protein 281
chr1_-_154155594 4.615 TPM3
tropomyosin 3
chr2_+_149402559 4.527 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_-_33793441 4.472 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr6_+_41020939 4.439 NM_006789
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr19_-_47615485 4.365 ZC3H4
zinc finger CCCH-type containing 4
chr1_-_154164551 4.349 NM_152263
TPM3
tropomyosin 3
chr18_-_74728677 4.336 MBP
myelin basic protein
chr7_+_148892553 4.282 NM_003575
ZNF282
zinc finger protein 282
chr3_-_69171536 4.260 NM_198271
LMOD3
leiomodin 3 (fetal)
chr1_-_144931967 4.255 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_+_42190825 4.214 TRAK1
trafficking protein, kinesin binding 1
chr8_-_121824268 4.169 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr5_+_148206155 4.062 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr8_-_121824287 3.984 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr1_-_148202535 3.956 NM_001164261
NM_001164262
PPIAL4D
PPIAL4F
peptidylprolyl isomerase A (cyclophilin A)-like 4D
peptidylprolyl isomerase A (cyclophilin A)-like 4F
chr1_-_144364203 3.942 NM_178230
NM_001143883
NM_001135789
PPIAL4A
PPIAL4G
PPIAL4B
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4A
peptidylprolyl isomerase A (cyclophilin A)-like 4G
peptidylprolyl isomerase A (cyclophilin A)-like 4B
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr17_-_49124128 3.933 NM_001251971
SPAG9
sperm associated antigen 9
chr1_-_143767849 3.930 NM_001123068
PPIAL4G
peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr8_-_145025043 3.894 NM_201380
PLEC
plectin
chr1_+_167905796 3.879 NM_001017977
NM_001198956
NM_001198957
NM_018442
DCAF6



DDB1 and CUL4 associated factor 6



chr17_+_26369617 3.846 NM_016231
NLK
nemo-like kinase
chr3_+_42727010 3.792 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr12_-_89745753 3.790 DUSP6
dual specificity phosphatase 6
chr18_-_74729049 3.783 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr12_-_49392909 3.719 NM_015086
DDN
dendrin
chr15_-_41408409 3.691 INO80
INO80 homolog (S. cerevisiae)
chr3_+_45636176 3.651 NM_014240
LIMD1
LIM domains containing 1
chr20_-_3765747 3.643 CENPB
centromere protein B, 80kDa
chr2_+_241808161 3.643 NM_000030
AGXT
alanine-glyoxylate aminotransferase
chr15_-_41408329 3.633 NM_017553
INO80
INO80 homolog (S. cerevisiae)
chrX_-_153285262 3.623 IRAK1
interleukin-1 receptor-associated kinase 1
chrY_+_2803409 3.600 NM_001145275
NM_003411
ZFY

zinc finger protein, Y-linked

chr8_+_121823538 3.589


chr20_-_50179167 3.587 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chrX_+_48456122 3.570 WDR13
WD repeat domain 13
chr18_+_11851388 3.568 NM_020412
CHMP1B
charged multivesicular body protein 1B
chr18_-_74728963 3.517 MBP
myelin basic protein
chr17_-_42466840 3.485 NM_000419
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr17_-_1531543 3.460 SLC43A2
solute carrier family 43, member 2
chr5_-_180670732 3.432 GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_+_167905921 3.426 DCAF6
DDB1 and CUL4 associated factor 6
chr6_+_43265994 3.374 NM_006672
NM_153320
SLC22A7

solute carrier family 22 (organic anion transporter), member 7

chr20_+_30697291 3.333 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr20_-_34243118 3.299 RBM12
RNA binding motif protein 12
chr1_-_154155680 3.291 TPM3
tropomyosin 3
chr22_-_24110054 3.283 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr15_-_60884615 3.240 NM_134262
RORA
RAR-related orphan receptor A
chr5_+_139876504 3.233 ANKHD1
ankyrin repeat and KH domain containing 1
chr1_-_154155646 3.219 TPM3
tropomyosin 3
chr18_-_72920989 3.214


chr1_+_27101217 3.211 ARID1A
AT rich interactive domain 1A (SWI-like)
chr20_+_30697512 3.210 TM9SF4
transmembrane 9 superfamily protein member 4
chrX_-_46618471 3.186 NM_032591
SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr7_-_139477437 3.182 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chrX_-_46618596 3.167 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr14_+_100705432 3.166 YY1
YY1 transcription factor
chr1_+_167906055 3.158 DCAF6
DDB1 and CUL4 associated factor 6
chr2_+_149402321 3.119 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr2_+_128175989 3.111 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr17_+_72832064 3.073 TMEM104
transmembrane protein 104
chr1_-_200377262 3.073 ZNF281
zinc finger protein 281
chr5_+_70944968 3.059 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr19_+_46850344 3.039 PPP5C
protein phosphatase 5, catalytic subunit
chr1_-_211751719 3.029 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr21_+_43639202 3.028 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr1_-_154155637 3.016 TPM3
tropomyosin 3
chr3_-_12705329 2.997 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr12_+_122459791 2.991 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr1_-_55681024 2.978 NM_015306
USP24
ubiquitin specific peptidase 24
chr1_-_154155636 2.945 TPM3
tropomyosin 3
chr2_-_97509733 2.929 NM_144994
ANKRD23
ankyrin repeat domain 23
chr19_-_3985343 2.901 EEF2
eukaryotic translation elongation factor 2
chr5_+_176562084 2.878 NSD1
nuclear receptor binding SET domain protein 1
chr1_-_154155698 2.874 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chr16_-_4322695 2.856 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr3_+_197677049 2.855 NM_000996
RPL35A
ribosomal protein L35a
chr2_-_44065888 2.855 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr1_-_154155685 2.843 TPM3
tropomyosin 3
chr11_-_129872719 2.840 NM_020228
NM_199437
PRDM10

PR domain containing 10

chr3_-_126194710 2.813 ZXDC
ZXD family zinc finger C
chr17_-_76719671 2.805 CYTH1
cytohesin 1
chr19_+_4791727 2.805 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr3_+_50654600 2.791 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr3_+_50654868 2.782 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr11_+_4470524 2.779 NM_001005172
OR52K2
olfactory receptor, family 52, subfamily K, member 2
chr19_+_46850245 2.762 NM_001204284
NM_006247
PPP5C

protein phosphatase 5, catalytic subunit

chr19_+_49468587 2.756 FTL
ferritin, light polypeptide
chr2_-_211179765 2.744 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr19_+_49468557 2.740 NM_000146
FTL
ferritin, light polypeptide
chr19_+_4791757 2.717 FEM1A
fem-1 homolog a (C. elegans)
chrX_+_48456220 2.715 NM_001166426
WDR13
WD repeat domain 13
chr16_+_47495166 2.703 NM_000293
NM_001031835
PHKB

phosphorylase kinase, beta

chr1_-_144931707 2.700 PDE4DIP
phosphodiesterase 4D interacting protein
chr4_-_23891608 2.695 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_+_244214576 2.693 ZNF238
zinc finger protein 238
chr19_-_39322411 2.686 NM_001398
ECH1
enoyl CoA hydratase 1, peroxisomal
chr3_-_12705612 2.676 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr20_-_50179338 2.653 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr7_+_150065968 2.652 REPIN1
replication initiator 1
chr14_-_95599794 2.641 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr11_-_6462129 2.640 NM_000613
HPX
hemopexin
chr1_+_149553002 2.639 NM_178230
NM_001143883
NM_001135789
PPIAL4A
PPIAL4G
PPIAL4B
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4A
peptidylprolyl isomerase A (cyclophilin A)-like 4G
peptidylprolyl isomerase A (cyclophilin A)-like 4B
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr17_-_4851797 2.638 NM_005022
PFN1
profilin 1
chr17_-_4851827 2.632 PFN1
profilin 1
chr3_+_50654558 2.632 NM_001243925
NM_004635
MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3

chr3_-_171177851 2.632 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr7_-_150884918 2.624 NM_080871
ASB10
ankyrin repeat and SOCS box containing 10
chr6_+_43266008 2.619 SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr9_-_123342258 2.600 NM_001011649
NM_018249
CDK5RAP2

CDK5 regulatory subunit associated protein 2

chr19_+_4791756 2.600 FEM1A
fem-1 homolog a (C. elegans)
chr2_+_44066102 2.587 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr10_-_70092648 2.585 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr1_+_222885895 2.569 NM_144695
BROX
BRO1 domain and CAAX motif containing
chr21_+_17102286 2.566 USP25
ubiquitin specific peptidase 25
chr2_+_128176019 2.546 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr7_-_37025696 2.544 ELMO1
engulfment and cell motility 1
chr15_-_90347534 2.542 ANPEP
alanyl (membrane) aminopeptidase
chr2_+_200819928 2.536 NM_024520
C2orf47
chromosome 2 open reading frame 47
chr1_-_211751953 2.532 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr17_-_9694613 2.521 NM_001105571
NM_001220493
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr13_-_76055872 2.508 NM_014832
TBC1D4
TBC1 domain family, member 4
chr6_+_42883726 2.501 NM_001243168
NM_001243169
NM_001243170
NM_138296
PTCRA



pre T-cell antigen receptor alpha



chr19_+_16771912 2.485 NM_024074
TMEM38A
transmembrane protein 38A
chr17_+_36861398 2.484 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_+_50654589 2.469 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr8_+_9953061 2.466 NM_001135671
NM_001199729
MSRA

methionine sulfoxide reductase A

chr19_+_2269526 2.466 OAZ1
ornithine decarboxylase antizyme 1
chr17_+_45727558 2.465 KPNB1
karyopherin (importin) beta 1
chr21_+_34922923 2.456 SON
SON DNA binding protein
chr1_-_149858114 2.452 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr5_-_180670874 2.450 NM_006098
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chrX_-_153285334 2.443 NM_001025242
NM_001025243
NM_001569
IRAK1


interleukin-1 receptor-associated kinase 1


chr15_-_25684161 2.425 NM_000462
NM_130839
UBE3A

ubiquitin protein ligase E3A

chr12_-_4554779 2.421 NM_020996
FGF6
fibroblast growth factor 6
chr15_-_67546968 2.414 NM_024666
AAGAB
alpha- and gamma-adaptin binding protein
chr11_-_118900078 2.408 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr21_+_17102370 2.403 NM_013396
USP25
ubiquitin specific peptidase 25
chr1_+_145507556 2.403 NM_005105
RBM8A
RNA binding motif protein 8A
chr12_+_57849086 2.393 NM_031479
INHBE
inhibin, beta E
chr11_-_61124223 2.377 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr19_+_2269529 2.375 OAZ1
ornithine decarboxylase antizyme 1
chr1_+_244214552 2.372 NM_205768
ZNF238
zinc finger protein 238
chr10_-_32636084 2.367 NM_025209
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr6_+_108882104 2.366 FOXO3
forkhead box O3
chr2_+_178257371 2.359 NM_003659
AGPS
alkylglycerone phosphate synthase
chrY_+_22737610 2.338 NM_004681
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr20_-_36152952 2.335 NM_001167823
BLCAP
bladder cancer associated protein
chr10_+_81073763 2.330 ZMIZ1
zinc finger, MIZ-type containing 1
chr16_+_47495225 2.317 PHKB
phosphorylase kinase, beta
chr3_-_128840343 2.315 RAB43
RAB43, member RAS oncogene family
chr11_-_62996998 2.314 NM_199352
SLC22A25
solute carrier family 22, member 25
chr2_-_21228189 2.284 APOB
apolipoprotein B (including Ag(x) antigen)
chr9_-_123476578 2.278 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr11_+_111473099 2.273 NM_015191
SIK2
salt-inducible kinase 2
chr11_+_33350076 2.271 HIPK3
homeodomain interacting protein kinase 3
chr10_-_32635842 2.268 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr20_-_49547451 2.267 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr1_+_27023932 2.266 ARID1A
AT rich interactive domain 1A (SWI-like)
chr10_+_104503724 2.266 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr3_+_42190736 2.264 TRAK1
trafficking protein, kinesin binding 1
chr7_+_123295860 2.264 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr12_+_56862300 2.263 NM_207344
SPRYD4
SPRY domain containing 4
chr14_-_23504353 2.261 NM_001144932
NM_002797
NM_001130725
PSMB5


proteasome (prosome, macropain) subunit, beta type, 5


chr19_+_2269515 2.255 NM_004152
OAZ1
SPPL2B
ornithine decarboxylase antizyme 1
signal peptide peptidase-like 2B
chr17_-_40169670 2.247 NM_003315
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr16_-_68057098 2.246 DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr5_+_176560882 2.244 NSD1
nuclear receptor binding SET domain protein 1
chr16_-_68057120 2.240 DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr1_-_162381805 2.239 NM_053282
SH2D1B
SH2 domain containing 1B
chr19_-_13044524 2.238 FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr6_+_27775898 2.235 NM_003509
HIST1H2AI
HIST1H2AM
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H2am
histone cluster 1, H3f
chr2_+_178257488 2.235 AGPS
alkylglycerone phosphate synthase
chr3_+_134514044 2.222 NM_004441
EPHB1
EPH receptor B1
chr6_+_111408780 2.219 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr19_-_14224979 2.216 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr17_+_74732629 2.214 NM_001242534
MFSD11
major facilitator superfamily domain containing 11
chr17_-_2240677 2.204 NM_018128
TSR1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr19_-_13044528 2.197 NM_004461
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr15_-_25684059 2.196 UBE3A
ubiquitin protein ligase E3A
chr12_-_49960221 2.185 NM_001012300
MCRS1
microspherule protein 1
chr18_+_55102777 2.183 NM_004852
ONECUT2
one cut homeobox 2
chr11_-_62559423 2.166 NM_001080501
TMEM223
transmembrane protein 223
chr17_-_41856180 2.158 NM_004090
DUSP3
dual specificity phosphatase 3
chr12_+_98987389 2.153 NM_002635
NM_005888
NM_213611
SLC25A3


solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3


chr1_-_154155664 2.152 TPM3
tropomyosin 3
chr15_-_90347173 2.151 ANPEP
alanyl (membrane) aminopeptidase

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.47 3.28e-15 GO:0044237 cellular metabolic process
1.56 2.20e-12 GO:0044260 cellular macromolecule metabolic process
1.37 2.26e-11 GO:0008152 metabolic process
1.40 2.60e-11 GO:0044238 primary metabolic process
1.46 1.69e-09 GO:0043170 macromolecule metabolic process
1.57 9.26e-08 GO:0034641 cellular nitrogen compound metabolic process
1.62 1.48e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.79 3.12e-07 GO:0010467 gene expression
1.54 4.53e-07 GO:0006807 nitrogen compound metabolic process
1.64 5.70e-07 GO:0044267 cellular protein metabolic process
1.17 1.89e-06 GO:0009987 cellular process
1.78 2.18e-06 GO:0016070 RNA metabolic process
1.97 3.53e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.90 8.45e-06 GO:0009893 positive regulation of metabolic process
1.60 1.12e-05 GO:0044249 cellular biosynthetic process
2.76 3.99e-05 GO:0044419 interspecies interaction between organisms
1.99 4.31e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.56 5.43e-05 GO:0009058 biosynthetic process
2.22 5.87e-05 GO:0010628 positive regulation of gene expression
2.27 6.88e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.60 7.82e-05 GO:0090304 nucleic acid metabolic process
1.52 1.11e-04 GO:0048518 positive regulation of biological process
2.02 1.81e-04 GO:0009891 positive regulation of biosynthetic process
2.16 2.61e-04 GO:0051254 positive regulation of RNA metabolic process
2.09 2.66e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.79 2.93e-04 GO:0006412 translation
1.41 4.19e-04 GO:0080090 regulation of primary metabolic process
1.66 4.73e-04 GO:0034645 cellular macromolecule biosynthetic process
1.80 5.39e-04 GO:0031325 positive regulation of cellular metabolic process
1.46 5.70e-04 GO:0019538 protein metabolic process
1.51 8.12e-04 GO:0048522 positive regulation of cellular process
1.64 8.28e-04 GO:0009059 macromolecule biosynthetic process
1.41 9.24e-04 GO:0060255 regulation of macromolecule metabolic process
1.95 1.13e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.54 1.16e-03 GO:0048523 negative regulation of cellular process
1.99 1.27e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.36 2.35e-03 GO:0019222 regulation of metabolic process
1.98 2.45e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 2.74e-03 GO:0031323 regulation of cellular metabolic process
1.86 4.78e-03 GO:0051704 multi-organism process
1.48 5.32e-03 GO:0048519 negative regulation of biological process
1.56 6.88e-03 GO:0044281 small molecule metabolic process
1.77 7.35e-03 GO:0042981 regulation of apoptosis
1.75 8.46e-03 GO:0010941 regulation of cell death
1.76 9.77e-03 GO:0043067 regulation of programmed cell death
1.85 1.13e-02 GO:0043933 macromolecular complex subunit organization
1.77 1.45e-02 GO:0032774 RNA biosynthetic process
1.72 1.74e-02 GO:0051246 regulation of protein metabolic process
1.44 1.82e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.15 1.94e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.12 2.04e-02 GO:0034621 cellular macromolecular complex subunit organization
6.09 2.16e-02 GO:0006941 striated muscle contraction
1.43 2.53e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.42 2.65e-02 GO:0010468 regulation of gene expression
1.40 2.71e-02 GO:0051171 regulation of nitrogen compound metabolic process
3.01 3.42e-02 GO:0006936 muscle contraction
2.14 4.91e-02 GO:0032583 regulation of gene-specific transcription

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.25 8.43e-20 GO:0044424 intracellular part
1.24 2.57e-19 GO:0005622 intracellular
1.27 7.50e-14 GO:0043226 organelle
1.30 9.16e-14 GO:0043227 membrane-bounded organelle
1.27 9.86e-14 GO:0043229 intracellular organelle
1.30 1.41e-13 GO:0043231 intracellular membrane-bounded organelle
1.47 1.50e-13 GO:0005634 nucleus
1.31 1.89e-12 GO:0005737 cytoplasm
1.56 8.55e-10 GO:0032991 macromolecular complex
1.72 4.76e-09 GO:0070013 intracellular organelle lumen
1.71 5.16e-09 GO:0043233 organelle lumen
1.68 1.72e-08 GO:0031974 membrane-enclosed lumen
1.96 2.78e-08 GO:0005654 nucleoplasm
1.69 7.59e-08 GO:0044428 nuclear part
1.36 9.96e-08 GO:0044446 intracellular organelle part
1.35 1.12e-07 GO:0044422 organelle part
1.74 2.25e-07 GO:0031981 nuclear lumen
1.29 1.27e-05 GO:0044444 cytoplasmic part
2.30 4.50e-05 GO:0030529 ribonucleoprotein complex
1.57 4.96e-05 GO:0005829 cytosol
2.07 5.33e-05 GO:0044451 nucleoplasm part
1.06 2.22e-04 GO:0044464 cell part
1.06 2.27e-04 GO:0005623 cell
1.39 1.42e-03 GO:0043234 protein complex
4.37 1.01e-02 GO:0000502 proteasome complex
1.35 2.44e-02 GO:0043228 non-membrane-bounded organelle
1.35 2.44e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.31 1.43e-09 GO:0005515 protein binding
1.45 1.65e-05 GO:0003676 nucleic acid binding
2.02 2.86e-05 GO:0003723 RNA binding
2.63 5.93e-04 GO:0008134 transcription factor binding
1.74 3.23e-03 GO:0030528 transcription regulator activity
1.44 5.42e-03 GO:0000166 nucleotide binding
12.51 9.44e-03 GO:0046965 retinoid X receptor binding
11.37 1.67e-02 GO:0017127 cholesterol transporter activity
2.28 1.92e-02 GO:0016563 transcription activator activity
2.13 2.66e-02 GO:0003712 transcription cofactor activity
1.77 2.73e-02 GO:0019899 enzyme binding
10.43 2.77e-02 GO:0042974 retinoic acid receptor binding
2.13 2.80e-02 GO:0000988 protein binding transcription factor activity
2.13 2.80e-02 GO:0000989 transcription factor binding transcription factor activity
9.62 4.36e-02 GO:0015248 sterol transporter activity
1.09 4.59e-02 GO:0005488 binding