Motif ID: YY1.p2

Z-value: 4.717


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
YY1 7528 YY1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
YY1hg19_v1_chr14_+_100705432_1007055800.125.0e-01Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_121824015 8.018


chr8_-_121823696 7.945 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr12_+_6647339 7.908 GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr1_+_148644010 7.091 NM_001144032
 PPIAL4E
peptidylprolyl isomerase A (cyclophilin A)-like 4E
chr5_-_149669187 6.611 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr19_-_47615802 6.264


chr17_+_65040651 6.057 NM_000727
 CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr17_+_26369935 6.022 NLK
nemo-like kinase
chr12_+_81101407 5.822 NM_002469
 MYF6
myogenic factor 6 (herculin)
chr22_-_36013303 5.447 NM_005368
NM_203378
 MB

myoglobin

chr17_-_62050200 5.372 NM_000334
 SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr19_-_55895602 5.365 NM_001190764
 TMEM238
transmembrane protein 238
chr5_-_149669400 5.288 NM_015981
NM_171825
 CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr1_-_200377488 4.704 ZNF281
zinc finger protein 281
chr1_-_154155594 4.615 TPM3
tropomyosin 3
chr2_+_149402559 4.527 NM_015630
 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_-_33793441 4.472 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr6_+_41020939 4.439 NM_006789
 APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr19_-_47615485 4.365 ZC3H4
zinc finger CCCH-type containing 4
chr1_-_154164551 4.349 NM_152263
 TPM3
tropomyosin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 57 entries
Enrichment   P-value GO Accession GO Term
6.09 2.16e-02 GO:0006941 striated muscle contraction
3.01 3.42e-02 GO:0006936 muscle contraction
2.79 2.93e-04 GO:0006412 translation
2.76 3.99e-05 GO:0044419 interspecies interaction between organisms
2.27 6.88e-05 GO:0045893 positive regulation of transcription, DNA-dependent
2.22 5.87e-05 GO:0010628 positive regulation of gene expression
2.16 2.61e-04 GO:0051254 positive regulation of RNA metabolic process
2.15 1.94e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.14 4.91e-02 GO:0032583 regulation of gene-specific transcription
2.12 2.04e-02 GO:0034621 cellular macromolecular complex subunit organization
2.09 2.66e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.02 1.81e-04 GO:0009891 positive regulation of biosynthetic process
1.99 4.31e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.99 1.27e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.98 2.45e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.97 3.53e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.95 1.13e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.90 8.45e-06 GO:0009893 positive regulation of metabolic process
1.86 4.78e-03 GO:0051704 multi-organism process
1.85 1.13e-02 GO:0043933 macromolecular complex subunit organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
Enrichment   P-value GO Accession GO Term
4.37 1.01e-02 GO:0000502 proteasome complex
2.30 4.50e-05 GO:0030529 ribonucleoprotein complex
2.07 5.33e-05 GO:0044451 nucleoplasm part
1.96 2.78e-08 GO:0005654 nucleoplasm
1.74 2.25e-07 GO:0031981 nuclear lumen
1.72 4.76e-09 GO:0070013 intracellular organelle lumen
1.71 5.16e-09 GO:0043233 organelle lumen
1.69 7.59e-08 GO:0044428 nuclear part
1.68 1.72e-08 GO:0031974 membrane-enclosed lumen
1.57 4.96e-05 GO:0005829 cytosol
1.56 8.55e-10 GO:0032991 macromolecular complex
1.47 1.50e-13 GO:0005634 nucleus
1.39 1.42e-03 GO:0043234 protein complex
1.36 9.96e-08 GO:0044446 intracellular organelle part
1.35 1.12e-07 GO:0044422 organelle part
1.35 2.44e-02 GO:0043228 non-membrane-bounded organelle
1.35 2.44e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.31 1.89e-12 GO:0005737 cytoplasm
1.30 9.16e-14 GO:0043227 membrane-bounded organelle
1.30 1.41e-13 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
12.51 9.44e-03 GO:0046965 retinoid X receptor binding
11.37 1.67e-02 GO:0017127 cholesterol transporter activity
10.43 2.77e-02 GO:0042974 retinoic acid receptor binding
9.62 4.36e-02 GO:0015248 sterol transporter activity
2.63 5.93e-04 GO:0008134 transcription factor binding
2.28 1.92e-02 GO:0016563 transcription activator activity
2.13 2.66e-02 GO:0003712 transcription cofactor activity
2.13 2.80e-02 GO:0000988 protein binding transcription factor activity
2.13 2.80e-02 GO:0000989 transcription factor binding transcription factor activity
2.02 2.86e-05 GO:0003723 RNA binding
1.77 2.73e-02 GO:0019899 enzyme binding
1.74 3.23e-03 GO:0030528 transcription regulator activity
1.45 1.65e-05 GO:0003676 nucleic acid binding
1.44 5.42e-03 GO:0000166 nucleotide binding
1.31 1.43e-09 GO:0005515 protein binding
1.09 4.59e-02 GO:0005488 binding