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Motif ID: ZBTB16.p2

Z-value: 2.054

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_53600999	16.466	NM_000889	ITGB7	integrin, beta 7
chr12_-_53601051	14.567		ITGB7	integrin, beta 7
chr5_+_156607847	14.156	NM_005546	ITK	IL2-inducible T-cell kinase
chr12_-_10562142	13.888	NM_013431	KLRC4-KLRK1 KLRC4	KLRC4-KLRK1 readthrough killer cell lectin-like receptor subfamily C, member 4
chr5_+_57787260	13.303	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr13_-_99910548	12.659	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr1_+_172628157	12.589	NM_000639	FASLG	Fas ligand (TNF superfamily, member 6)
chr1_+_198608136	11.970	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr1_+_198608216	11.508		PTPRC	protein tyrosine phosphatase, receptor type, C
chr12_-_10282680	11.382	NM_022570 NM_197947 NM_197948 NM_197949 NM_197950 NM_197954	CLEC7A	C-type lectin domain family 7, member A
chr1_+_198608244	11.009		PTPRC	protein tyrosine phosphatase, receptor type, C
chr12_+_10460416	10.788	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr4_-_38784588	10.725	NM_001017388 NM_001195106 NM_001195107 NM_001195108 NM_030956	TLR10	toll-like receptor 10
chr14_-_106478129	10.654		IGHV4-31 IGHD IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr2_-_89292396	10.001		IGKC	immunoglobulin kappa constant
chr3_+_46395224	9.854	NM_001123041 NM_001123396	CCR2	chemokine (C-C motif) receptor 2
chr19_-_54824343	9.641	NM_021250 NM_181879 NM_181985 NM_181986	LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr12_+_69742130	9.573	NM_000239	LYZ	lysozyme
chr5_+_35856990	9.233	NM_002185	IL7R	interleukin 7 receptor
chr4_+_74606222	9.086	NM_000584	IL8	interleukin 8
chr9_-_117156684	7.935	NM_030767	AKNA	AT-hook transcription factor
chr12_+_69742140	7.836		LYZ	lysozyme
chr2_+_204801453	7.566	NM_012092	ICOS	inducible T-cell co-stimulator
chr14_-_106610338	7.502		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_+_9980076	7.435	NM_016523	KLRF1	killer cell lectin-like receptor subfamily F, member 1
chr3_+_186714335	7.430
chr3_+_32993065	7.333	NM_005508	CCR4	chemokine (C-C motif) receptor 4
chr11_-_104827421	7.130	NM_033306	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr19_+_14693895	7.066	NM_001204118 NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr14_-_106725620	6.930		IGHV4-31 IGHV3-23 IGHA1 IGHG1 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-23 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr6_-_159466019	6.557	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr14_+_88471467	6.517	NM_003608	GPR65	G protein-coupled receptor 65
chr2_+_202125222	6.393	NM_033356	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr19_-_14785626	6.276	NM_032571	EMR3	egf-like module containing, mucin-like, hormone receptor-like 3
chr19_-_14889347	6.243	NM_013447 NM_152916 NM_152917 NM_152918 NM_152919 NM_152920 NM_152921	EMR2	egf-like module containing, mucin-like, hormone receptor-like 2
chr5_+_96212167	6.037		ERAP2	endoplasmic reticulum aminopeptidase 2
chr10_+_90521162	5.827	NM_001102469	LIPN	lipase, family member N
chr7_+_26400503	5.758	NM_001199837	SNX10	sorting nexin 10
chr4_+_36283243	5.716	NM_001136536	DTHD1	death domain containing 1
chr12_-_10588543	5.701	NM_002260	KLRC2 KLRC3	killer cell lectin-like receptor subfamily C, member 2 killer cell lectin-like receptor subfamily C, member 3
chr12_+_54892567	5.571	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr13_-_46756291	5.525		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_192127591	5.446	NM_130782	RGS18	regulator of G-protein signaling 18
chr3_+_122044010	5.369	NM_005213	CSTA	cystatin A (stefin A)
chr11_-_118095708	5.307	NM_001098526	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr2_-_89619820	5.277		IGKC	immunoglobulin kappa constant
chr14_-_106725232	5.091		ZCWPW2 IGHV3-23 IGKV3-20 IGK@	zinc finger, CW type with PWWP domain 2 immunoglobulin heavy variable 3-23 immunoglobulin kappa variable 3-20 immunoglobulin kappa locus
chr3_+_46395574	5.084		CCR2	chemokine (C-C motif) receptor 2
chr11_+_122709205	5.081	NM_019604	CRTAM	cytotoxic and regulatory T cell molecule
chr8_-_37727937	4.971		RAB11FIP1	RAB11 family interacting protein 1 (class I)
chr5_+_54398473	4.917	NM_006144	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr6_-_31560497	4.860	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr3_+_108541544	4.716	NM_016388	TRAT1	T cell receptor associated transmembrane adaptor 1
chr7_-_36764000	4.690	NM_001177506 NM_001177507 NM_001637	AOAH	acyloxyacyl hydrolase (neutrophil)
chr21_+_43823970	4.661	NM_001001895 NM_001243467 NM_018961	UBASH3A	ubiquitin associated and SH3 domain containing A
chr12_-_9885859	4.643	NM_001253748 NM_001253750 NM_172004	CLECL1	C-type lectin-like 1
chr6_+_27777713	4.642	NM_003536	HIST1H3H	histone cluster 1, H3h
chr2_-_32490688	4.631	NM_001199139 NM_021209	NLRC4	NLR family, CARD domain containing 4
chr12_-_10562744	4.616	NM_001199805	KLRC4-KLRK1	KLRC4-KLRK1 readthrough
chr13_-_99959649	4.515	NM_004951	GPR183	G protein-coupled receptor 183
chr3_+_136649316	4.497	NM_001190796	NCK1	NCK adaptor protein 1
chr15_+_81489218	4.479	NM_001172128	IL16	interleukin 16
chr11_+_5710816	4.454	NM_001199573 NM_006074	TRIM22	tripartite motif containing 22
chr12_+_10103914	4.452	NM_001207010	CLEC12A	C-type lectin domain family 12, member A
chr16_-_21663908	4.365		IGSF6	immunoglobulin superfamily, member 6
chr4_-_39033981	4.354	NM_024943	TMEM156	transmembrane protein 156
chr15_+_58430394	4.343	NM_020980	AQP9	aquaporin 9
chr3_+_46283871	4.331	NM_001164680 NM_001837 NM_178328 NM_178329	CCR3	chemokine (C-C motif) receptor 3
chr14_-_107013122	4.321		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_+_111765725	4.300	NM_019903	ADD3	adducin 3 (gamma)
chr7_-_38313232	4.288	NM_001003799 NM_001003806	TARP TRGV9	TCR gamma alternate reading frame protein T cell receptor gamma variable 9
chr12_+_14538232	4.275		ATF7IP	activating transcription factor 7 interacting protein
chr7_+_106505876	4.261	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr19_-_48752921	4.215	NM_001184901 NM_001184903 NM_014959	CARD8	caspase recruitment domain family, member 8
chr22_+_22723972	4.082
chr2_+_204571379	4.025		CD28	CD28 molecule
chr11_-_104905849	4.011		CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr10_-_65028825	3.985	NM_004241	JMJD1C	jumonji domain containing 1C
chr19_-_51920841	3.959	NM_001171156 NM_001171157 NM_001171158 NM_001171159 NM_001171160 NM_001171161 NM_033130	SIGLEC10	sialic acid binding Ig-like lectin 10
chr3_+_121774208	3.953	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr6_+_167525294	3.935	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr9_+_273025	3.892	NM_001190458 NM_001193536	DOCK8	dedicator of cytokinesis 8
chrX_+_12885190	3.870	NM_016562	TLR7	toll-like receptor 7
chr18_+_61582744	3.841	NM_005024	SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr17_-_29648631	3.790	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr16_-_21663962	3.781	NM_005849	IGSF6	immunoglobulin superfamily, member 6
chr14_-_106714594	3.767
chr4_-_84035908	3.765	NM_001130715 NM_016619	PLAC8	placenta-specific 8
chr14_-_99737821	3.761	NM_022898 NM_138576	BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)
chr17_+_42634598	3.742	NM_001466	FZD2	frizzled family receptor 2
chr6_-_108145507	3.726	NM_198081	SCML4	sex comb on midleg-like 4 (Drosophila)
chr5_+_54320083	3.657	NM_002104	GZMK	granzyme K (granzyme 3; tryptase II)
chr14_-_106471439	3.638		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr14_-_99737554	3.623		BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)
chr12_+_60083125	3.609	NM_004731	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr12_-_10573041	3.605	NM_002261 NM_007333	KLRC3	killer cell lectin-like receptor subfamily C, member 3
chr3_+_98250742	3.598	NM_005290	GPR15	G protein-coupled receptor 15
chr11_-_104893894	3.591	NM_001136109 NM_001136110 NM_001136112 NM_004347	CASP5	caspase 5, apoptosis-related cysteine peptidase
chr19_-_20748540	3.567	NM_001159293	ZNF737	zinc finger protein 737
chr4_-_84035888	3.556		PLAC8	placenta-specific 8
chr15_-_55562483	3.544	NM_183234 NM_004580	RAB27A	RAB27A, member RAS oncogene family
chr22_+_23229959	3.533	NM_001178126	IGLL5 IGLC1	immunoglobulin lambda-like polypeptide 5 immunoglobulin lambda constant 1 (Mcg marker)
chr8_-_66701175	3.515	NM_002603	PDE7A	phosphodiesterase 7A
chr3_+_39371196	3.495	NM_005201	CCR8	chemokine (C-C motif) receptor 8
chr3_-_151102536	3.482	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr17_+_65936590	3.415		BPTF	bromodomain PHD finger transcription factor
chr11_-_104972147	3.339	NM_001007232 NM_001223 NM_033292 NM_033293 NM_033294 NM_033295	CARD17 CASP1	caspase recruitment domain family, member 17 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr19_-_48759141	3.328	NM_001184902 NM_001184904	CARD8	caspase recruitment domain family, member 8
chr2_+_161993465	3.311	NM_004180 NM_133484	TANK	TRAF family member-associated NFKB activator
chr3_-_56809594	3.294	NM_001128616	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr6_-_32977351	3.257	NM_002119	HLA-DOA	major histocompatibility complex, class II, DO alpha
chr19_+_48758931	3.229		LOC100505812	uncharacterized LOC100505812
chr12_-_10151689	3.219	NM_001099431 NM_016509	CLEC1B	C-type lectin domain family 1, member B
chr13_-_41556360	3.180	NM_001145353	ELF1	E74-like factor 1 (ets domain transcription factor)
chr14_+_70236266	3.147		SRSF5	serine/arginine-rich splicing factor 5
chr9_+_135854097	3.147	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr13_+_32313678	3.112	NM_001166058 NM_130806	RXFP2	relaxin/insulin-like family peptide receptor 2
chr1_+_160709038	3.103	NM_021181	SLAMF7	SLAM family member 7
chr1_-_111743297	3.102		DENND2D	DENN/MADD domain containing 2D
chr11_-_104916041	3.061	NM_001017534 NM_052889	CARD16	caspase recruitment domain family, member 16
chr16_-_12897632	3.058		CPPED1	calcineurin-like phosphoesterase domain containing 1
chr14_-_106877689	3.045		IGHV4-31 IGH@ IGHA1 IGHA2 IGHG1 IGHG4 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 4 (G4m marker) immunoglobulin heavy constant mu
chr1_-_20445991	3.011	NM_012400	PLA2G2D	phospholipase A2, group IID
chr6_-_49712055	3.010	NM_001190986 NM_006061	CRISP3	cysteine-rich secretory protein 3
chr5_-_94224601	2.995		MCTP1	multiple C2 domains, transmembrane 1
chr10_+_8097350	2.943		GATA3	GATA binding protein 3
chr14_-_106452693	2.931		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_23855456	2.904		RPL9	ribosomal protein L9
chr14_-_106691698	2.848
chr7_-_104909442	2.847	NM_182691	SRPK2	SRSF protein kinase 2
chr1_+_241695433	2.846	NM_003679	KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr19_-_55458864	2.843	NM_001127255 NM_139176 NM_206828	NLRP7	NLR family, pyrin domain containing 7
chr11_+_60146022	2.816		MS4A7	membrane-spanning 4-domains, subfamily A, member 7
chr16_-_12897693	2.814	NM_001099455 NM_018340	CPPED1	calcineurin-like phosphoesterase domain containing 1
chr3_+_122296432	2.793	NM_001113523	PARP15	poly (ADP-ribose) polymerase family, member 15
chr4_+_71091787	2.787	NM_152997	C4orf7	chromosome 4 open reading frame 7
chr7_+_28725597	2.783	NM_001011666	CREB5	cAMP responsive element binding protein 5
chrX_+_1387692	2.777	NM_001161529 NM_001161531 NM_001161532 NM_006140 NM_172245 NM_172246 NM_172249	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr2_+_202047620	2.771	NM_001206524 NM_001206542 NM_001230 NM_032974 NM_032976 NM_032977	CASP10	caspase 10, apoptosis-related cysteine peptidase
chr10_-_32667543	2.768		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr9_-_71590754	2.765
chr19_+_20277991	2.755	NM_052852	ZNF486	zinc finger protein 486
chr10_-_27057776	2.752		ABI1	abl-interactor 1
chr1_-_150738255	2.737		CTSS	cathepsin S
chr3_-_183273407	2.704	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr14_-_107211131	2.695		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_90049818	2.689	NM_001001323 NM_001682	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr1_+_174844655	2.675	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr1_+_247712395	2.673	NM_145278	C1orf150	chromosome 1 open reading frame 150
chr5_+_49961732	2.669	NM_001178055	PARP8	poly (ADP-ribose) polymerase family, member 8
chr12_+_15699277	2.625	NM_030668 NM_030669 NM_030670 NM_030671	PTPRO	protein tyrosine phosphatase, receptor type, O
chr4_+_15779887	2.618	NM_001775	CD38	CD38 molecule
chr17_-_3599298	2.558		P2RX5	purinergic receptor P2X, ligand-gated ion channel, 5
chr19_+_7504573	2.539	NM_001130955	ARHGEF18	Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr3_-_150920946	2.531	NM_013308	GPR171	G protein-coupled receptor 171
chr7_-_115670811	2.525		TFEC	transcription factor EC
chr13_-_41593405	2.512		ELF1	E74-like factor 1 (ets domain transcription factor)
chr4_+_40198526	2.496	NM_004310	RHOH	ras homolog gene family, member H
chr5_-_147162251	2.492	NM_014790	JAKMIP2	janus kinase and microtubule interacting protein 2
chr12_+_10124007	2.492	NM_138337 NM_201623	CLEC12A CLEC12B	C-type lectin domain family 12, member A C-type lectin domain family 12, member B
chr7_+_150264457	2.488	NM_018326	GIMAP4	GTPase, IMAP family member 4
chrY_+_1337692	2.488	NM_001161529 NM_001161531 NM_001161532 NM_006140 NM_172245 NM_172246 NM_172249	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr8_+_74903563	2.483	NM_001195797 NM_015364	LY96	lymphocyte antigen 96
chr12_-_80307690	2.460	NM_001143886	PPP1R12A	protein phosphatase 1, regulatory subunit 12A
chr10_+_70847817	2.456	NM_002727	SRGN	serglycin
chr13_-_41556188	2.437		ELF1	E74-like factor 1 (ets domain transcription factor)
chr2_+_204571197	2.431	NM_001243077 NM_001243078 NM_006139	CD28	CD28 molecule
chr11_+_60163486	2.425	NM_001079692 NM_032597	MS4A14	membrane-spanning 4-domains, subfamily A, member 14
chr14_-_45722332	2.405		MIS18BP1	MIS18 binding protein 1
chr17_+_61086897	2.404	NM_025185	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr7_-_115670774	2.404		TFEC	transcription factor EC
chr6_-_44233244	2.393		NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr8_+_24151579	2.376	NM_014265 NM_021777	ADAM28	ADAM metallopeptidase domain 28
chr2_-_38303265	2.374		CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1
chr6_-_33041266	2.370	NM_033554	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1
chr17_-_6983503	2.369	NM_006344 NM_182906	CLEC10A	C-type lectin domain family 10, member A
chr16_+_81812897	2.360	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_84647342	2.359	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr3_-_172241060	2.348	NM_001190943 NM_001190942 NM_003810	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
chr14_-_106692107	2.328		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chrX_-_19688991	2.312	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr8_+_11351509	2.299	NM_001715	BLK	B lymphoid tyrosine kinase
chr12_+_25205488	2.290		LRMP	lymphoid-restricted membrane protein
chr7_+_76090971	2.282	NM_001102594 NM_001102595 NM_020892	DTX2	deltex homolog 2 (Drosophila)
chr17_-_3599359	2.277		P2RX5	purinergic receptor P2X, ligand-gated ion channel, 5
chr6_-_46703429	2.271	NM_001168357	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr11_+_5710926	2.267		TRIM22	tripartite motif containing 22
chr19_+_37717365	2.261	NM_152604	ZNF383	zinc finger protein 383
chr3_-_151058439	2.261	NM_176876	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr20_-_1638359	2.253	NM_001039508 NM_018556 NM_080816	SIRPG	signal-regulatory protein gamma
chr20_-_1538303	2.229	NM_178460	SIRPD	signal-regulatory protein delta
chr11_+_63273523	2.225	NM_001142535 NM_001142536 NM_033101	LGALS12	lectin, galactoside-binding, soluble, 12
chr16_+_81812899	2.205		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr20_-_52199635	2.199	NM_006526	ZNF217	zinc finger protein 217
chr11_+_5641173	2.196	NM_001003827	TRIM34	tripartite motif containing 34
chr21_-_35884503	2.188		KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr4_+_15704752	2.175		BST1	bone marrow stromal cell antigen 1
chr2_-_38303307	2.173	NM_000104	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1
chr3_+_68053358	2.146	NM_213609	FAM19A1	family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr6_-_24877453	2.140	NM_015864	FAM65B	family with sequence similarity 65, member B

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.70	4.47e-22	GO:0002376	immune system process
4.46	2.45e-19	GO:0006955	immune response
3.92	6.06e-13	GO:0002682	regulation of immune system process
3.49	1.49e-11	GO:0006952	defense response
4.55	4.61e-11	GO:0002684	positive regulation of immune system process
4.50	6.21e-11	GO:0050776	regulation of immune response
5.13	5.13e-09	GO:0050778	positive regulation of immune response
2.30	2.02e-08	GO:0007166	cell surface receptor linked signaling pathway
6.33	2.66e-08	GO:0002757	immune response-activating signal transduction
5.38	3.18e-08	GO:0045321	leukocyte activation
3.11	3.28e-08	GO:0048584	positive regulation of response to stimulus
6.18	4.15e-08	GO:0002764	immune response-regulating signaling pathway
5.56	4.17e-08	GO:0002253	activation of immune response
2.24	4.80e-08	GO:0048583	regulation of response to stimulus
1.53	5.75e-08	GO:0050896	response to stimulus
8.16	1.47e-07	GO:0002429	immune response-activating cell surface receptor signaling pathway
7.85	2.69e-07	GO:0002768	immune response-regulating cell surface receptor signaling pathway
2.85	3.40e-07	GO:0009611	response to wounding
1.80	3.55e-07	GO:0007165	signal transduction
3.62	5.05e-07	GO:0001775	cell activation
5.97	6.79e-07	GO:0051251	positive regulation of lymphocyte activation
5.57	8.17e-07	GO:0046649	lymphocyte activation
5.23	9.81e-07	GO:0051249	regulation of lymphocyte activation
1.97	1.00e-06	GO:0006950	response to stress
5.56	2.27e-06	GO:0002696	positive regulation of leukocyte activation
5.47	3.02e-06	GO:0050867	positive regulation of cell activation
7.75	4.38e-06	GO:0050851	antigen receptor-mediated signaling pathway
1.69	5.27e-06	GO:0023052	signaling
4.75	5.70e-06	GO:0002694	regulation of leukocyte activation
4.56	1.14e-05	GO:0050865	regulation of cell activation
6.33	6.39e-05	GO:0042110	T cell activation
5.77	7.45e-05	GO:0050870	positive regulation of T cell activation
1.76	1.58e-04	GO:0048518	positive regulation of biological process
5.44	1.62e-04	GO:0002252	immune effector process
7.76	2.16e-04	GO:0050671	positive regulation of lymphocyte proliferation
7.66	2.49e-04	GO:0032946	positive regulation of mononuclear cell proliferation
7.55	2.87e-04	GO:0070665	positive regulation of leukocyte proliferation
3.87	3.90e-04	GO:0006954	inflammatory response
3.46	3.90e-04	GO:0045087	innate immune response
6.18	7.59e-04	GO:0050670	regulation of lymphocyte proliferation
10.84	7.66e-04	GO:0030888	regulation of B cell proliferation
1.54	8.08e-04	GO:0051716	cellular response to stimulus
6.12	8.47e-04	GO:0032944	regulation of mononuclear cell proliferation
3.82	9.45e-04	GO:0001817	regulation of cytokine production
12.87	1.14e-03	GO:0030890	positive regulation of B cell proliferation
5.94	1.17e-03	GO:0070663	regulation of leukocyte proliferation
8.58	1.22e-03	GO:0006968	cellular defense response
4.66	1.24e-03	GO:0050863	regulation of T cell activation
16.26	1.56e-03	GO:0050853	B cell receptor signaling pathway
15.45	2.20e-03	GO:0009595	detection of biotic stimulus
3.46	2.33e-03	GO:0051050	positive regulation of transport
1.31	2.67e-03	GO:0065007	biological regulation
2.16	5.83e-03	GO:0010941	regulation of cell death
2.45	6.27e-03	GO:0051049	regulation of transport
1.31	7.62e-03	GO:0050789	regulation of biological process
5.35	9.51e-03	GO:0007204	elevation of cytosolic calcium ion concentration
2.14	9.71e-03	GO:0043067	regulation of programmed cell death
2.76	1.16e-02	GO:0007596	blood coagulation
2.76	1.16e-02	GO:0050817	coagulation
25.75	1.27e-02	GO:0032700	negative regulation of interleukin-17 production
2.74	1.30e-02	GO:0007599	hemostasis
9.01	1.46e-02	GO:0071260	cellular response to mechanical stimulus
8.79	1.74e-02	GO:0050871	positive regulation of B cell activation
15.15	1.90e-02	GO:0032660	regulation of interleukin-17 production
2.10	1.90e-02	GO:0042981	regulation of apoptosis
6.18	2.01e-02	GO:0050852	T cell receptor signaling pathway
4.19	2.12e-02	GO:0031349	positive regulation of defense response
5.42	2.19e-02	GO:0030098	lymphocyte differentiation
5.37	2.41e-02	GO:0032103	positive regulation of response to external stimulus
6.87	2.76e-02	GO:0050864	regulation of B cell activation
4.76	2.88e-02	GO:0051480	cytosolic calcium ion homeostasis
5.80	3.41e-02	GO:0006959	humoral immune response
1.30	3.99e-02	GO:0050794	regulation of cellular process
1.63	4.05e-02	GO:0048522	positive regulation of cellular process
4.57	4.24e-02	GO:0002521	leukocyte differentiation

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.47	9.15e-04	GO:0005886	plasma membrane
1.47	1.05e-03	GO:0071944	cell periphery
1.96	2.52e-03	GO:0005887	integral to plasma membrane
1.92	3.99e-03	GO:0031226	intrinsic to plasma membrane
1.62	1.14e-02	GO:0044459	plasma membrane part

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
12.87	1.01e-06	GO:0003823	antigen binding
15.45	1.05e-06	GO:0001614	purinergic nucleotide receptor activity
15.45	1.05e-06	GO:0016502	nucleotide receptor activity
2.12	1.29e-06	GO:0004872	receptor activity
17.91	2.11e-06	GO:0001608	nucleotide receptor activity, G-protein coupled
17.91	2.11e-06	GO:0045028	purinergic nucleotide receptor activity, G-protein coupled
13.63	3.60e-06	GO:0035586	purinergic receptor activity
4.88	1.03e-05	GO:0005529	sugar binding
1.92	1.04e-05	GO:0004871	signal transducer activity
1.92	1.04e-05	GO:0060089	molecular transducer activity
3.25	2.46e-04	GO:0030246	carbohydrate binding
2.00	1.65e-03	GO:0004888	transmembrane receptor activity
25.75	2.70e-03	GO:0016493	C-C chemokine receptor activity
22.89	4.78e-03	GO:0019957	C-C chemokine binding
12.26	1.24e-02	GO:0015026	coreceptor activity
13.73	4.72e-02	GO:0008329	pattern recognition receptor activity