Motif ID: ZBTB6.p2

Z-value: 1.356


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB6hg19_v1_chr9_-_125675571_1256756080.336.2e-02Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_230579198 3.692 NM_139072
 DNER
delta/notch-like EGF repeat containing
chr5_+_139175385 3.657 NM_032289
 PSD2
pleckstrin and Sec7 domain containing 2
chr14_+_24540742 3.320 NM_006032
 CPNE6
copine VI (neuronal)
chr8_+_104512975 3.293 NM_001100117
 RIMS2
regulating synaptic membrane exocytosis 2
chr3_+_181429711 3.251 NM_003106
 SOX2
SRY (sex determining region Y)-box 2
chr9_+_34958320 2.988 KIAA1045
KIAA1045
chr22_+_26565424 2.917 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
 SEZ6L





seizure related 6 homolog (mouse)-like





chr3_+_10857867 2.651 NM_014229
 SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr5_+_175298604 2.615 CPLX2
complexin 2
chr4_+_159131642 2.527 TMEM144
transmembrane protein 144
chr1_-_160039946 2.458 NM_002241
 KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr11_+_33563772 2.421 NM_012194
 C11orf41
chromosome 11 open reading frame 41
chr22_-_39240016 2.417 NM_014293
 NPTXR
neuronal pentraxin receptor
chr9_+_87284625 2.398 NM_001007097
 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr5_+_175298492 2.305 NM_001008220
 CPLX2
complexin 2
chr9_+_87284680 2.298 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr3_+_181430075 2.288 SOX2
SRY (sex determining region Y)-box 2
chr12_-_6809595 2.277 NM_001244015
 C12orf53
chromosome 12 open reading frame 53
chr5_+_175308843 2.275 CPLX2
complexin 2
chr4_-_163085117 2.272 NM_001128427
NM_001128428
NM_020116
 FSTL5


follistatin-like 5



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
8.50 4.32e-02 GO:0006836 neurotransmitter transport
6.16 1.22e-06 GO:0007268 synaptic transmission
5.81 9.90e-07 GO:0019226 transmission of nerve impulse
5.81 9.90e-07 GO:0035637 multicellular organismal signaling
4.22 2.62e-05 GO:0007267 cell-cell signaling
4.08 1.04e-02 GO:0007417 central nervous system development
3.60 2.58e-08 GO:0007399 nervous system development
3.50 1.37e-04 GO:0007154 cell communication
3.46 1.60e-02 GO:0030182 neuron differentiation
3.37 3.38e-03 GO:0048699 generation of neurons
3.35 1.93e-03 GO:0022008 neurogenesis
2.97 3.08e-02 GO:0048468 cell development
1.99 1.78e-02 GO:0048731 system development
1.94 1.33e-03 GO:0023052 signaling
1.89 3.02e-02 GO:0048856 anatomical structure development
1.83 3.91e-02 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
Enrichment   P-value GO Accession GO Term
12.84 2.89e-02 GO:0030672 synaptic vesicle membrane
8.76 7.09e-03 GO:0019717 synaptosome
8.50 3.40e-02 GO:0030665 clathrin coated vesicle membrane
8.30 3.79e-02 GO:0008021 synaptic vesicle
6.92 6.97e-04 GO:0030425 dendrite
6.80 2.63e-03 GO:0043025 neuronal cell body
6.61 3.24e-03 GO:0044297 cell body
6.41 1.27e-07 GO:0043005 neuron projection
6.33 1.54e-07 GO:0045202 synapse
6.02 8.16e-05 GO:0044456 synapse part
3.54 8.54e-05 GO:0042995 cell projection
3.32 1.66e-02 GO:0030054 cell junction
2.88 4.08e-04 GO:0005887 integral to plasma membrane
2.82 5.59e-04 GO:0031226 intrinsic to plasma membrane
2.42 6.57e-05 GO:0044459 plasma membrane part
1.93 2.75e-05 GO:0071944 cell periphery
1.92 4.65e-05 GO:0005886 plasma membrane
1.73 9.21e-05 GO:0031224 intrinsic to membrane
1.71 6.51e-06 GO:0044425 membrane part
1.70 2.86e-04 GO:0016021 integral to membrane

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
11.46 1.14e-02 GO:0004714 transmembrane receptor protein tyrosine kinase activity
3.46 4.32e-03 GO:0005509 calcium ion binding