Motif ID: ZNF238.p2

Z-value: 2.876


Transcription factors associated with ZNF238.p2:

Gene SymbolEntrez IDGene Name
ZNF238 10472 zinc finger protein 238

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF238hg19_v1_chr1_+_244214552_244214560-0.421.6e-02Click!


Activity profile for motif ZNF238.p2.

activity profile for motif ZNF238.p2


Sorted Z-values histogram for motif ZNF238.p2

Sorted Z-values for motif ZNF238.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF238.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_55512801 35.583 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_-_123065836 20.427 CLMP
CXADR-like membrane protein
chr1_-_168698412 20.091 NM_001937
DPT
dermatopontin
chr19_-_11305186 18.171 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr19_+_11649578 18.109 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr17_+_47653176 16.837 NM_007225
NXPH3
neurexophilin 3
chr17_+_47653474 16.373 NXPH3
neurexophilin 3
chr5_-_44388666 14.909 NM_004465
FGF10
fibroblast growth factor 10
chr15_+_49715374 14.891 NM_002009
FGF7
fibroblast growth factor 7
chr2_+_189839078 14.606 NM_000090
COL3A1
collagen, type III, alpha 1
chr11_-_68780667 14.571 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr2_+_189839113 14.257 COL3A1
collagen, type III, alpha 1
chr2_+_189839132 13.637 COL3A1
collagen, type III, alpha 1
chr17_+_77020229 11.625 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chrX_+_99899162 11.389 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr1_-_17307107 11.110 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr1_+_53527822 11.097 NM_001199081
PODN
podocan
chr17_+_77020278 10.714 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_-_203320185 10.092 FMOD
fibromodulin
chr1_+_53527723 10.032 NM_001199080
NM_001199082
NM_153703
PODN


podocan


chrX_+_13587693 9.973 NM_001167890
NM_015507
EGFL6

EGF-like-domain, multiple 6

chr11_+_76494132 9.870 NM_015516
TSKU
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr1_-_203320287 9.580 NM_002023
FMOD
fibromodulin
chr16_-_65155881 8.776 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr20_+_30063090 8.750 NM_014012
REM1
RAS (RAD and GEM)-like GTP-binding 1
chrX_-_101771641 8.750 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr13_+_113777112 8.664 NM_000504
F10
coagulation factor X
chr14_-_38725253 8.608 CLEC14A
C-type lectin domain family 14, member A
chrX_+_99899388 8.237 SRPX2
sushi-repeat containing protein, X-linked 2
chrX_+_100333835 8.116 NM_021637
TMEM35
transmembrane protein 35
chr16_-_65155965 8.093 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr2_-_163099877 8.078 NM_004460
FAP
fibroblast activation protein, alpha
chr1_-_203320249 7.968


chr17_-_53809444 7.519 NM_001099640
TMEM100
transmembrane protein 100
chr14_+_94577078 7.502 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr14_-_38725539 7.385 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr1_-_171621750 7.383 NM_000261
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr1_+_19972259 7.324 NM_001204086
NBL1
neuroblastoma, suppression of tumorigenicity 1
chrX_+_99839789 7.267 NM_022144
TNMD
tenomodulin
chr10_-_131762017 7.258 NM_001005463
EBF3
early B-cell factor 3
chr1_-_16344438 7.116 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr16_-_65155984 7.108 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_-_104443914 7.053 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr4_-_152149042 6.752 NM_001243349
SH3D19
SH3 domain containing 19
chr12_-_104443698 6.506 GLT8D2
glycosyltransferase 8 domain containing 2
chr5_-_178772430 6.183 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr11_-_11643542 6.166 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr17_+_36584692 6.094 NM_001199417
ARHGAP23
Rho GTPase activating protein 23
chr9_-_129884998 6.092 NM_012098
ANGPTL2
angiopoietin-like 2
chr12_-_29936685 6.039 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr9_+_72658496 5.859 NM_153267
MAMDC2
MAM domain containing 2
chr12_+_58005217 5.783 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr17_-_67138013 5.758 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr7_-_135433366 5.663 NM_205855
FAM180A
family with sequence similarity 180, member A
chr8_+_24241797 5.541 NM_001145271
NM_001145272
NM_014479
ADAMDEC1


ADAM-like, decysin 1


chr2_+_201473942 5.466 AOX1
aldehyde oxidase 1
chr12_+_13349716 5.422 EMP1
epithelial membrane protein 1
chr20_+_56725982 5.405 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr5_+_172068188 5.356 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr5_-_178772328 5.299 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr5_+_15500539 5.247 FBXL7
F-box and leucine-rich repeat protein 7
chr11_+_75273100 5.207 NM_001207014
NM_001235
SERPINH1

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

chr9_-_129884961 5.163 ANGPTL2
angiopoietin-like 2
chr1_+_212781969 5.115 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr9_+_72658735 5.074 MAMDC2
MAM domain containing 2
chr11_+_46299585 5.073 CREB3L1
cAMP responsive element binding protein 3-like 1
chr9_-_124984018 5.072 NM_001242335
LHX6
LIM homeobox 6
chr11_+_46299554 5.050 CREB3L1
cAMP responsive element binding protein 3-like 1
chr5_+_15500288 5.017 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr3_+_100211408 4.907 NM_018004
TMEM45A
transmembrane protein 45A
chr11_+_75273245 4.904 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr13_-_86373328 4.825 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_212782103 4.786 ATF3
activating transcription factor 3
chr2_+_108994366 4.764 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr4_+_15376174 4.729 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr17_+_60705042 4.713 MRC2
mannose receptor, C type 2
chr7_+_45197366 4.641 NM_005856
RAMP3
receptor (G protein-coupled) activity modifying protein 3
chr12_+_13349720 4.613 EMP1
epithelial membrane protein 1
chr4_+_166794409 4.535 NM_001204760
NM_012464
TLL1

tolloid-like 1

chr9_+_124329398 4.509 NM_032552
DAB2IP
DAB2 interacting protein
chr17_+_48133331 4.199 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr15_-_74043815 4.119 NM_001039614
C15orf59
chromosome 15 open reading frame 59
chr8_-_49833823 4.101 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr12_+_2162388 4.075 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr8_-_17555158 4.053 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr8_+_1772095 4.023 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr20_+_3713316 4.005 NM_001197327
NM_052970
HSPA12B

heat shock 70kD protein 12B

chr17_-_53800074 3.964 NM_018286
TMEM100
transmembrane protein 100
chr19_-_36001336 3.945 NM_001126059
DMKN
dermokine
chr17_-_15168590 3.931 NM_000304
PMP22
peripheral myelin protein 22
chr3_+_100211554 3.914 TMEM45A
transmembrane protein 45A
chr4_+_113970784 3.891 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr5_+_31799030 3.885 NM_178140
PDZD2
PDZ domain containing 2
chr16_+_57392694 3.868 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr19_-_46272496 3.847 NM_175875
SIX5
SIX homeobox 5
chr17_+_60705051 3.812 MRC2
mannose receptor, C type 2
chr1_-_156647088 3.794 NM_006617
NES
nestin
chr14_-_61748510 3.751 NM_001017970
TMEM30B
transmembrane protein 30B
chr12_-_106532447 3.664 NUAK1
NUAK family, SNF1-like kinase, 1
chr11_-_33722285 3.631 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr1_-_27709781 3.584 NM_207397
CD164L2
CD164 sialomucin-like 2
chr12_-_102874158 3.568 IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_+_32612686 3.537 NM_002986
CCL11
chemokine (C-C motif) ligand 11
chr1_+_110993748 3.457 NM_032414
PROK1
prokineticin 1
chr12_+_26348268 3.440 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr10_+_99473478 3.384 MARVELD1
MARVEL domain containing 1
chr7_+_30737600 3.379 INMT
indolethylamine N-methyltransferase
chr6_+_44195008 3.375 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr11_-_57004674 3.306 NM_005161
APLNR
apelin receptor
chr8_+_17354562 3.294 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr18_+_29078026 3.249 NM_001943
DSG2
desmoglein 2
chr12_+_41086189 3.239 NM_001843
NM_175038
CNTN1

contactin 1

chr17_-_62050200 3.237 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr17_-_42345434 3.198 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr14_-_21271002 3.182 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr1_+_44446176 3.168 NM_001005417
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr2_-_65659634 3.147 NM_181784
SPRED2
sprouty-related, EVH1 domain containing 2
chr14_-_106746056 3.130


chr18_+_54814292 3.066 BOD1P
biorientation of chromosomes in cell division 1 pseudogene
chr16_-_11375094 3.057 NM_002761
PRM1
protamine 1
chr18_-_52969714 3.042 NM_001243236
TCF4
transcription factor 4
chr2_-_1748240 3.028 PXDN
peroxidasin homolog (Drosophila)
chr1_+_233749749 3.004 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr1_+_64936475 3.004 NM_020925
CACHD1
cache domain containing 1
chr11_+_2159910 3.001


chr9_-_34710062 2.990 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr6_-_163148800 2.959 NM_004562
NM_013987
NM_013988
PARK2


parkinson protein 2, E3 ubiquitin protein ligase (parkin)


chr20_-_6103562 2.957 FERMT1
fermitin family member 1
chr10_+_99473456 2.956 NM_031484
MARVELD1
MARVEL domain containing 1
chr20_+_13202417 2.953 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr21_-_40033617 2.945 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr9_+_87283453 2.883 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr19_-_18902077 2.879 NM_000095
COMP
cartilage oligomeric matrix protein
chr3_-_189838907 2.861 NM_018192
LEPREL1
leprecan-like 1
chr11_+_46299161 2.724 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr20_-_49253425 2.713 NM_080829
FAM65C
family with sequence similarity 65, member C
chr5_+_140782367 2.652 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr1_-_178840079 2.637 NM_004673
ANGPTL1
angiopoietin-like 1
chr12_+_26348488 2.635 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr5_-_134369841 2.629 NM_002653
PITX1
paired-like homeodomain 1
chr6_+_163149001 2.614 NM_001080379
PACRG
PARK2 co-regulated
chr19_-_22193720 2.606 NM_007153
ZNF208
zinc finger protein 208
chr11_-_2159472 2.579 IGF2
insulin-like growth factor 2 (somatomedin A)
chr18_+_6834431 2.548 NM_001010000
ARHGAP28
Rho GTPase activating protein 28
chr12_-_15942116 2.537 EPS8
epidermal growth factor receptor pathway substrate 8
chr19_+_7828034 2.532 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr16_-_31146992 2.513 PRSS8
protease, serine, 8
chr11_-_57089670 2.488 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr20_+_30225690 2.476 NM_032609
COX4I2
cytochrome c oxidase subunit IV isoform 2 (lung)
chr4_+_153864134 2.468 NM_033393
FHDC1
FH2 domain containing 1
chr14_-_107199126 2.456 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106573348 2.440 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr6_-_39197225 2.434 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr2_+_71162995 2.432 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr11_+_114310107 2.384 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr2_+_159651828 2.380 NM_001017920
DAPL1
death associated protein-like 1
chr16_-_70099755 2.379 PDXDC2P
pyridoxal-dependent decarboxylase domain containing 2, pseudogene
chr2_-_1748285 2.366 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chrX_+_153170528 2.363 NM_000054
NM_001146151
AVPR2

arginine vasopressin receptor 2

chr1_+_213123853 2.355 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr14_+_95047792 2.353 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr19_+_3585541 2.304 NM_133261
GIPC3
GIPC PDZ domain containing family, member 3
chr3_+_46919235 2.301 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr7_+_144015217 2.237 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr2_+_239756672 2.205 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr1_-_208059254 2.203


chr11_-_62457370 2.192 NM_203422
LRRN4CL
LRRN4 C-terminal like
chr8_-_145770680 2.192 ARHGAP39
Rho GTPase activating protein 39
chr3_+_30647901 2.164 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr12_-_53343607 2.162 KRT8
keratin 8
chr16_-_1280162 2.120 NM_024164
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr8_+_92114846 2.118 NM_001129890
LRRC69
leucine rich repeat containing 69
chr4_-_105416050 2.116 CXXC4
CXXC finger protein 4
chrX_-_10588458 2.111 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr11_-_2159784 2.107 IGF2
insulin-like growth factor 2 (somatomedin A)
chr5_-_148758787 2.106 NM_014443
IL17B
interleukin 17B
chr19_-_49243836 2.094 NM_017805
RASIP1
Ras interacting protein 1
chr6_-_30523933 2.093 GNL1
guanine nucleotide binding protein-like 1
chr6_-_163148716 2.086 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr11_-_5537815 2.059 NM_145053
UBQLNL
ubiquilin-like
chr1_+_204042191 2.057 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr6_-_30523502 2.030 GNL1
guanine nucleotide binding protein-like 1
chr14_+_104605441 2.010 KIF26A
kinesin family member 26A
chrX_-_110513750 1.927 NM_014289
CAPN6
calpain 6
chr12_+_52300691 1.921 ACVRL1
activin A receptor type II-like 1
chr8_+_38965049 1.903 NM_145004
ADAM32
ADAM metallopeptidase domain 32
chr16_-_31147062 1.901 NM_002773
PRSS8
protease, serine, 8
chr11_+_5602106 1.898 NM_001005162
OR52B6
olfactory receptor, family 52, subfamily B, member 6
chrX_+_43515531 1.892 MAOA
monoamine oxidase A
chr17_-_34195745 1.892 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr12_-_53298765 1.887 NM_002273
KRT8
keratin 8
chrX_-_154563735 1.886 NM_001289
CLIC2
chloride intracellular channel 2
chr17_+_17398334 1.884


chr11_+_10326618 1.880 NM_001124
ADM
adrenomedullin
chr17_+_45908992 1.839 NM_033413
LRRC46
leucine rich repeat containing 46
chr21_-_43373938 1.814 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr1_+_183155173 1.807 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr19_-_35625610 1.790 LGI4
leucine-rich repeat LGI family, member 4
chr16_+_15068985 1.788 PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr16_-_29910340 1.779 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2






Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.61 1.29e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.95 7.66e-16 GO:0005576 extracellular region
3.94 8.35e-11 GO:0005615 extracellular space
3.44 1.62e-10 GO:0044421 extracellular region part
3.96 9.93e-05 GO:0031012 extracellular matrix
3.89 1.05e-03 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
6.48 6.58e-05 GO:0005539 glycosaminoglycan binding
5.99 1.53e-04 GO:0001871 pattern binding
5.99 1.53e-04 GO:0030247 polysaccharide binding
3.70 7.33e-04 GO:0030246 carbohydrate binding
11.90 1.88e-03 GO:0003823 antigen binding
6.43 2.10e-03 GO:0008201 heparin binding
3.13 3.17e-02 GO:0004175 endopeptidase activity
2.17 3.21e-02 GO:0005102 receptor binding