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Illumina Body Map 2, young vs old

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Results for AACGGAA

Z-value: 0.17

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miRNA associated with seed AACGGAA

NamemiRBASE accession
hsa-miR-191-5p
MIMAT0000440

Activity profile of AACGGAA motif

Sorted Z-values of AACGGAA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_69061594 0.65 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr8_-_134115118 0.23 ENST00000395352.3
ENST00000338087.5
SLA
Src-like-adaptor
chr17_-_46623441 0.19 ENST00000330070.4
HOXB2
homeobox B2
chr2_+_27193480 0.17 ENST00000233121.2
ENST00000405074.3
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr5_+_149887672 0.16 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr1_-_19283163 0.15 ENST00000455833.2
IFFO2
intermediate filament family orphan 2
chr12_-_58240470 0.14 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr12_+_122242597 0.14 ENST00000267197.5
SETD1B
SET domain containing 1B
chr2_-_208634287 0.13 ENST00000295417.3
FZD5
frizzled family receptor 5
chr7_-_92463210 0.11 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr10_+_114709999 0.11 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_-_117319236 0.10 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_-_17766198 0.10 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr22_+_51112800 0.10 ENST00000414786.2
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr8_-_141645645 0.10 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chrX_-_109561294 0.10 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_-_71801980 0.09 ENST00000329008.5
CALN1
calneuron 1
chr19_-_15560730 0.08 ENST00000389282.4
ENST00000263381.7
WIZ
widely interspaced zinc finger motifs
chrX_-_41782249 0.07 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr6_+_116601265 0.05 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr2_-_128643496 0.04 ENST00000272647.5
AMMECR1L
AMMECR1-like
chr6_+_21593972 0.04 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr11_-_67980744 0.03 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr16_-_71843047 0.03 ENST00000299980.4
ENST00000393512.3
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr19_+_3359561 0.02 ENST00000589123.1
ENST00000346156.5
ENST00000395111.3
ENST00000586919.1
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr7_-_17980091 0.02 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr3_-_52090461 0.02 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr3_-_18466787 0.02 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr1_+_33722080 0.02 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr17_-_7232585 0.01 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr1_+_61547894 0.01 ENST00000403491.3
NFIA
nuclear factor I/A
chr16_-_4897266 0.00 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)

Network of associatons between targets according to the STRING database.

First level regulatory network of AACGGAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773) positive regulation of long-term neuronal synaptic plasticity(GO:0048170) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)