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Illumina Body Map 2, young vs old

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Results for AAUCUCU

Z-value: 0.43

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miRNA associated with seed AAUCUCU

NamemiRBASE accession
hsa-miR-216b-5p
MIMAT0004959

Activity profile of AAUCUCU motif

Sorted Z-values of AAUCUCU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_67678818 1.06 ENST00000334583.6
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr11_+_60739140 0.88 ENST00000313421.7
CD6
CD6 molecule
chr14_+_71108460 0.81 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr11_+_12308447 0.59 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr19_-_4066890 0.47 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_+_21467642 0.47 ENST00000222584.3
ENST00000432066.2
SP4
Sp4 transcription factor
chr12_+_111471828 0.45 ENST00000261726.6
CUX2
cut-like homeobox 2
chr6_+_114178512 0.40 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr9_-_20622478 0.40 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_+_42749759 0.40 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr10_+_11206925 0.30 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr13_-_31038370 0.27 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr17_+_64298944 0.22 ENST00000413366.3
PRKCA
protein kinase C, alpha
chrX_+_122993827 0.19 ENST00000371199.3
XIAP
X-linked inhibitor of apoptosis
chr12_+_60083118 0.16 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_-_153895377 0.15 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr3_-_113465065 0.14 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr14_+_57735614 0.12 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr4_+_99916765 0.12 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr16_-_46723066 0.09 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr14_+_62037287 0.08 ENST00000556569.1
RP11-47I22.3
Uncharacterized protein
chr16_-_67840442 0.08 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RANBP10
RAN binding protein 10
chr5_+_149109825 0.07 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr17_+_30677136 0.07 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
ZNF207
zinc finger protein 207
chr2_-_242212227 0.06 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP
high density lipoprotein binding protein
chr1_+_107683644 0.06 ENST00000370067.1
NTNG1
netrin G1
chr7_+_35840542 0.05 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr2_+_48010221 0.04 ENST00000234420.5
MSH6
mutS homolog 6
chr8_+_48920960 0.03 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr8_+_76452097 0.02 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr15_-_100258029 0.01 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr18_+_59854480 0.01 ENST00000256858.6
ENST00000398130.2
KIAA1468
KIAA1468

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUCUCU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:1903179 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0007614 short-term memory(GO:0007614)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation