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Illumina Body Map 2, young vs old

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Results for AGGUAGU

Z-value: 0.04

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miRNA associated with seed AGGUAGU

NamemiRBASE accession
hsa-miR-196a-5p
MIMAT0000226
hsa-miR-196b-5p
MIMAT0001080

Activity profile of AGGUAGU motif

Sorted Z-values of AGGUAGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27196267 4.05 ENST00000242159.3
HOXA7
homeobox A7
chr12_+_54402790 3.21 ENST00000040584.4
HOXC8
homeobox C8
chr18_+_6834472 2.92 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
ARHGAP28
Rho GTPase activating protein 28
chr9_-_16870704 2.84 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr7_+_94023873 2.73 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr17_-_48278983 2.68 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr2_+_189839046 2.54 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr17_-_46688334 2.34 ENST00000239165.7
HOXB7
homeobox B7
chr7_-_27183263 2.34 ENST00000222726.3
HOXA5
homeobox A5
chr5_-_153857819 2.32 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr17_-_46682321 2.28 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chrX_+_105066524 2.25 ENST00000243300.9
ENST00000428173.2
NRK
Nik related kinase
chr7_-_27219632 2.12 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr3_-_120003941 1.80 ENST00000464295.1
GPR156
G protein-coupled receptor 156
chr6_-_94129244 1.75 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr7_-_27205136 1.54 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr5_-_158526756 1.52 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr18_+_19749386 1.49 ENST00000269216.3
GATA6
GATA binding protein 6
chrX_-_132549506 1.47 ENST00000370828.3
GPC4
glypican 4
chr9_+_132934835 1.45 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr5_+_38846101 1.34 ENST00000274276.3
OSMR
oncostatin M receptor
chr15_-_65715401 1.33 ENST00000352385.2
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr6_-_35464727 1.32 ENST00000402886.3
TEAD3
TEA domain family member 3
chr1_+_164528866 1.28 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr19_-_47975417 1.24 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr22_+_48972118 1.21 ENST00000358295.5
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr12_+_66217911 1.20 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr12_-_59313270 1.17 ENST00000379141.4
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr11_+_63580855 1.16 ENST00000294244.4
C11orf84
chromosome 11 open reading frame 84
chr9_+_109625378 1.15 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr17_+_8213590 1.10 ENST00000361926.3
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr11_+_63870660 1.09 ENST00000246841.3
FLRT1
fibronectin leucine rich transmembrane protein 1
chr3_-_48229846 0.98 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr3_-_21792838 0.94 ENST00000281523.2
ZNF385D
zinc finger protein 385D
chr16_+_29789561 0.93 ENST00000400752.4
ZG16
zymogen granule protein 16
chr19_-_51054299 0.92 ENST00000599957.1
LRRC4B
leucine rich repeat containing 4B
chr7_+_94285637 0.92 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr5_+_172068232 0.91 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr9_-_125693757 0.82 ENST00000373656.3
ZBTB26
zinc finger and BTB domain containing 26
chr9_+_19408999 0.80 ENST00000340967.2
ACER2
alkaline ceramidase 2
chr20_+_306221 0.79 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr7_-_83824169 0.78 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_-_42419649 0.77 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr8_+_121137333 0.72 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1
collagen, type XIV, alpha 1
chr1_-_86622421 0.68 ENST00000370571.2
COL24A1
collagen, type XXIV, alpha 1
chr12_-_25102252 0.68 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_+_65004292 0.68 ENST00000542104.1
ENST00000336061.2
RASSF3
Ras association (RalGDS/AF-6) domain family member 3
chr17_+_47074758 0.67 ENST00000290341.3
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr3_+_61547585 0.65 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr7_+_89841000 0.61 ENST00000287908.3
STEAP2
STEAP family member 2, metalloreductase
chr1_-_92351769 0.60 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr8_-_82754427 0.53 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
SNX16
sorting nexin 16
chr14_-_20020272 0.50 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chr21_-_39870339 0.50 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr4_-_42154895 0.49 ENST00000502486.1
ENST00000504360.1
BEND4
BEN domain containing 4
chr19_+_32836499 0.49 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr9_-_79520989 0.46 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr8_+_22102626 0.45 ENST00000519237.1
ENST00000397802.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr2_+_232260254 0.44 ENST00000287590.5
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr16_-_4987065 0.44 ENST00000590782.2
ENST00000345988.2
PPL
periplakin
chr1_+_65210772 0.41 ENST00000371072.4
ENST00000294428.3
RAVER2
ribonucleoprotein, PTB-binding 2
chr15_-_44486632 0.40 ENST00000484674.1
FRMD5
FERM domain containing 5
chr7_-_120498357 0.39 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr5_+_178286925 0.38 ENST00000322434.3
ZNF354B
zinc finger protein 354B
chr10_-_38146510 0.38 ENST00000395867.3
ZNF248
zinc finger protein 248
chr6_-_134373732 0.37 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chrX_-_83757399 0.37 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr4_+_106473768 0.36 ENST00000265154.2
ENST00000420470.2
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr14_+_19553365 0.36 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr6_-_33267101 0.35 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr4_+_55095264 0.34 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr18_-_74207146 0.34 ENST00000443185.2
ZNF516
zinc finger protein 516
chr7_+_114055052 0.33 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr8_-_28243934 0.32 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395
zinc finger protein 395
chr3_-_47823298 0.32 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr18_+_76740189 0.32 ENST00000537592.2
ENST00000575389.2
SALL3
spalt-like transcription factor 3
chr2_+_204192942 0.31 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr21_+_42539701 0.30 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2
beta-site APP-cleaving enzyme 2
chr9_+_6413317 0.30 ENST00000276893.5
ENST00000381373.3
UHRF2
ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
chr9_+_133710453 0.29 ENST00000318560.5
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr8_+_58907104 0.28 ENST00000361488.3
FAM110B
family with sequence similarity 110, member B
chr12_-_123450986 0.28 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr4_-_100575781 0.27 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr12_-_57472522 0.27 ENST00000379391.3
ENST00000300128.4
TMEM194A
transmembrane protein 194A
chr3_+_50712672 0.26 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr10_+_72238517 0.26 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr9_-_127533519 0.26 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chrX_+_17393543 0.25 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_-_50574856 0.25 ENST00000342183.5
NRXN1
neurexin 1
chr2_+_170590321 0.25 ENST00000392647.2
KLHL23
kelch-like family member 23
chr9_+_128509624 0.24 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr8_+_81397876 0.24 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr12_-_42877764 0.23 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr3_-_28390581 0.23 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr16_+_69221028 0.23 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr19_+_531713 0.23 ENST00000215574.4
CDC34
cell division cycle 34
chr5_+_153825510 0.22 ENST00000297109.6
SAP30L
SAP30-like
chr19_+_14063278 0.22 ENST00000254337.6
DCAF15
DDB1 and CUL4 associated factor 15
chr4_+_17616253 0.21 ENST00000237380.7
MED28
mediator complex subunit 28
chr1_-_17766198 0.21 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr12_+_110940005 0.20 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9B
RAD9 homolog B (S. pombe)
chr10_+_68685764 0.20 ENST00000361320.4
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr9_+_99212403 0.20 ENST00000375251.3
ENST00000375249.4
HABP4
hyaluronan binding protein 4
chr3_+_110790590 0.20 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr15_+_66994561 0.19 ENST00000288840.5
SMAD6
SMAD family member 6
chr16_+_22217577 0.19 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr14_-_57735528 0.18 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr1_+_50574585 0.18 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr7_-_98741642 0.17 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr15_+_36887069 0.16 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr16_+_447209 0.16 ENST00000382940.4
ENST00000219479.2
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr6_+_133562472 0.16 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4
eyes absent homolog 4 (Drosophila)
chr3_+_49209023 0.16 ENST00000332780.2
KLHDC8B
kelch domain containing 8B
chr15_+_38544476 0.16 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr6_-_99797522 0.15 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chrX_-_134186144 0.14 ENST00000370775.2
FAM127B
family with sequence similarity 127, member B
chrX_+_134166333 0.14 ENST00000257013.7
FAM127A
family with sequence similarity 127, member A
chr1_+_109102652 0.13 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr11_-_110583451 0.13 ENST00000260283.4
ENST00000528829.1
ARHGAP20
Rho GTPase activating protein 20
chr1_+_153232160 0.12 ENST00000368742.3
LOR
loricrin
chr1_+_113615794 0.12 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr6_+_134274322 0.11 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr12_-_102874416 0.11 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_-_46608272 0.11 ENST00000577092.1
ENST00000239174.6
HOXB1
homeobox B1
chr17_+_30771279 0.09 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr12_-_77459306 0.09 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7
E2F transcription factor 7
chr12_-_112123726 0.09 ENST00000419234.4
BRAP
BRCA1 associated protein
chr12_+_118814344 0.09 ENST00000397564.2
SUDS3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr10_+_98592009 0.08 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr15_-_50411412 0.08 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr12_+_4382917 0.07 ENST00000261254.3
CCND2
cyclin D2
chr14_+_72399833 0.06 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr9_-_135819987 0.05 ENST00000298552.3
ENST00000403810.1
TSC1
tuberous sclerosis 1
chr14_-_81687197 0.04 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr12_-_76478686 0.04 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chrX_+_95939711 0.04 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr12_+_123868320 0.04 ENST00000402868.3
ENST00000330479.4
SETD8
SET domain containing (lysine methyltransferase) 8
chr18_+_9475668 0.04 ENST00000383432.3
RALBP1
ralA binding protein 1
chr17_+_38375574 0.04 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr2_+_179345173 0.03 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr7_+_35840542 0.03 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr9_-_111929560 0.03 ENST00000561981.2
FRRS1L
ferric-chelate reductase 1-like
chr4_+_20702059 0.03 ENST00000444671.2
ENST00000510700.1
ENST00000506745.1
ENST00000514663.1
ENST00000509469.1
ENST00000515339.1
ENST00000513861.1
ENST00000502374.1
ENST00000538990.1
ENST00000511160.1
ENST00000504630.1
ENST00000513590.1
ENST00000514292.1
ENST00000502938.1
ENST00000509625.1
ENST00000505160.1
ENST00000507634.1
ENST00000513459.1
ENST00000511089.1
PACRGL
PARK2 co-regulated-like
chr9_+_110045537 0.02 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr12_-_29534074 0.02 ENST00000546839.1
ENST00000360150.4
ENST00000552155.1
ENST00000550353.1
ENST00000548441.1
ENST00000552132.1
ERGIC2
ERGIC and golgi 2
chr17_+_53342311 0.02 ENST00000226067.5
HLF
hepatic leukemia factor
chr17_-_61850894 0.02 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr18_+_67068228 0.02 ENST00000382713.5
DOK6
docking protein 6
chr6_+_107349392 0.02 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203
chromosome 6 open reading frame 203
chr9_-_14693417 0.02 ENST00000380916.4
ZDHHC21
zinc finger, DHHC-type containing 21
chr5_-_74326724 0.02 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr16_-_4166186 0.01 ENST00000294016.3
ADCY9
adenylate cyclase 9
chrX_-_24045303 0.01 ENST00000328046.8
KLHL15
kelch-like family member 15
chr21_+_47878757 0.01 ENST00000400274.1
ENST00000427143.2
ENST00000318711.7
ENST00000457905.3
ENST00000466639.1
ENST00000435722.3
ENST00000417564.2
DIP2A
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr18_-_18691739 0.01 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr3_-_150264272 0.01 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr2_-_39664405 0.00 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr1_-_179198702 0.00 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr16_-_30621663 0.00 ENST00000287461.3
ZNF689
zinc finger protein 689
chr2_+_242641442 0.00 ENST00000313552.6
ENST00000406941.1
ING5
inhibitor of growth family, member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of AGGUAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0060435 bronchiole development(GO:0060435)
0.8 2.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.7 2.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 2.7 GO:0044691 tooth eruption(GO:0044691)
0.6 2.3 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.5 1.5 GO:0007493 endodermal cell fate determination(GO:0007493)
0.3 4.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 1.2 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.3 2.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 2.7 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.8 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 1.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.9 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 0.8 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.7 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.7 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 1.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.3 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 0.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.5 GO:0042118 endothelial cell activation(GO:0042118)
0.1 2.8 GO:0003416 endochondral bone growth(GO:0003416)
0.1 0.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 2.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.4 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 2.3 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.3 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 2.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 5.5 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.0 1.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 1.5 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0018146 keratan sulfate biosynthetic process(GO:0018146) keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0005584 collagen type I trimer(GO:0005584)
0.4 1.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 2.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.7 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 1.0 GO:0031045 dense core granule(GO:0031045)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 4.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 1.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 1.2 GO:0035501 MH1 domain binding(GO:0035501)
0.3 0.8 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 1.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 0.6 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.2 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.7 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 2.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.1 1.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 1.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 10.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 3.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis