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Illumina Body Map 2, young vs old

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Results for AGUGGUU

Z-value: 0.23

Motif logo

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miRNA associated with seed AGUGGUU

NamemiRBASE accession
hsa-miR-140-5p
MIMAT0000431

Activity profile of AGUGGUU motif

Sorted Z-values of AGUGGUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_228135599 3.29 ENST00000272164.5
WNT9A
wingless-type MMTV integration site family, member 9A
chr2_-_217560248 2.95 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr5_+_32788945 2.60 ENST00000326958.1
AC026703.1
AC026703.1
chr6_+_168841817 2.50 ENST00000356284.2
ENST00000354536.5
SMOC2
SPARC related modular calcium binding 2
chr5_+_32711419 2.17 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr15_-_48937982 1.95 ENST00000316623.5
FBN1
fibrillin 1
chr5_-_172756506 1.93 ENST00000265087.4
STC2
stanniocalcin 2
chr4_-_174451370 1.83 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr7_-_120498357 1.80 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr4_+_124320665 1.74 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr4_-_152147579 1.73 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chr11_+_46299199 1.57 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr5_-_141704566 1.53 ENST00000344120.4
ENST00000434127.2
SPRY4
sprouty homolog 4 (Drosophila)
chr21_-_28338732 1.52 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr1_-_68299130 1.51 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr8_+_142402089 1.47 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr8_+_70378852 1.44 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr1_+_182992545 1.38 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr14_+_69726656 1.38 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr1_+_220701456 1.36 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr11_-_46940074 1.33 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr11_+_12695944 1.33 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_+_159141397 1.31 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr4_+_55095264 1.31 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr14_+_85996471 1.25 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr12_+_2162447 1.11 ENST00000335762.5
ENST00000399655.1
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr3_+_139654018 1.11 ENST00000458420.3
CLSTN2
calsyntenin 2
chr12_-_7245125 1.08 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr20_+_6748311 1.03 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr3_-_46037299 1.01 ENST00000296137.2
FYCO1
FYVE and coiled-coil domain containing 1
chr2_-_183903133 1.00 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr3_+_32147997 1.00 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr1_-_117210290 0.97 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr9_-_73029540 0.96 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr20_-_10654639 0.96 ENST00000254958.5
JAG1
jagged 1
chr9_+_112810878 0.94 ENST00000434623.2
ENST00000374525.1
AKAP2
A kinase (PRKA) anchor protein 2
chr4_+_77356248 0.92 ENST00000296043.6
SHROOM3
shroom family member 3
chr1_+_82266053 0.90 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr14_+_37131058 0.90 ENST00000361487.6
PAX9
paired box 9
chr14_+_37667118 0.87 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
MIPOL1
mirror-image polydactyly 1
chr19_-_41196534 0.85 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr6_+_43737939 0.84 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr1_+_78470530 0.78 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr15_-_56757329 0.77 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr17_+_40932610 0.75 ENST00000246914.5
WNK4
WNK lysine deficient protein kinase 4
chr3_+_174577070 0.72 ENST00000454872.1
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr9_+_112542572 0.70 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr7_-_42276612 0.70 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr7_-_79082867 0.70 ENST00000419488.1
ENST00000354212.4
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr16_+_69221028 0.68 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr1_+_64239657 0.66 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr6_+_21593972 0.65 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr15_+_38544476 0.65 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr15_-_83876758 0.65 ENST00000299633.4
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr4_-_111544254 0.62 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr2_-_213403565 0.60 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr17_+_31254892 0.59 ENST00000394642.3
ENST00000579849.1
TMEM98
transmembrane protein 98
chr15_-_30114622 0.58 ENST00000495972.2
ENST00000346128.6
TJP1
tight junction protein 1
chr17_+_46908350 0.51 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr6_+_53883708 0.51 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chr3_-_124774802 0.50 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chrX_-_154563889 0.49 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr7_-_44924939 0.49 ENST00000395699.2
PURB
purine-rich element binding protein B
chrX_+_37208521 0.48 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr19_+_48972459 0.46 ENST00000427476.1
CYTH2
cytohesin 2
chr3_+_57741957 0.45 ENST00000295951.3
SLMAP
sarcolemma associated protein
chr8_-_66754172 0.45 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr6_+_57037089 0.45 ENST00000370693.5
BAG2
BCL2-associated athanogene 2
chr10_+_60272814 0.45 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr10_+_70091812 0.44 ENST00000265866.7
HNRNPH3
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr1_-_33338076 0.44 ENST00000496770.1
FNDC5
fibronectin type III domain containing 5
chr3_-_149688896 0.44 ENST00000239940.7
PFN2
profilin 2
chrX_+_107069063 0.43 ENST00000262843.6
MID2
midline 2
chr1_+_175036966 0.42 ENST00000239462.4
TNN
tenascin N
chr18_+_32073253 0.42 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr8_-_80680078 0.41 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr12_+_113659234 0.41 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1
two pore segment channel 1
chr6_+_149068464 0.41 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr1_+_11994715 0.37 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr1_-_40137710 0.37 ENST00000235628.1
NT5C1A
5'-nucleotidase, cytosolic IA
chr12_+_45609893 0.37 ENST00000320560.8
ANO6
anoctamin 6
chr16_-_66785699 0.37 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr8_+_38854418 0.36 ENST00000481513.1
ENST00000487273.2
ADAM9
ADAM metallopeptidase domain 9
chr18_-_24445729 0.35 ENST00000383168.4
AQP4
aquaporin 4
chr9_+_132934835 0.34 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr7_+_114055052 0.34 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr11_+_9406169 0.34 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr15_-_42264702 0.34 ENST00000220325.4
EHD4
EH-domain containing 4
chr3_-_50396978 0.34 ENST00000266025.3
TMEM115
transmembrane protein 115
chr7_-_117513540 0.33 ENST00000160373.3
CTTNBP2
cortactin binding protein 2
chr4_+_78978724 0.32 ENST00000325942.6
ENST00000264895.6
ENST00000264899.6
FRAS1
Fraser syndrome 1
chr5_-_16936340 0.31 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr5_+_98104978 0.30 ENST00000308234.7
RGMB
repulsive guidance molecule family member b
chrX_+_70752917 0.29 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr4_-_146859623 0.29 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr12_+_107168342 0.28 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr14_+_96000930 0.27 ENST00000331334.4
GLRX5
glutaredoxin 5
chr7_+_128379346 0.27 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr5_-_77844974 0.26 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr10_+_60028818 0.25 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr6_-_82462425 0.25 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr6_+_143929307 0.24 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr2_+_14775215 0.24 ENST00000581929.1
AC011897.1
Uncharacterized protein
chr14_+_23775971 0.24 ENST00000250405.5
BCL2L2
BCL2-like 2
chr19_-_49258606 0.23 ENST00000310160.3
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr7_-_112430647 0.22 ENST00000312814.6
TMEM168
transmembrane protein 168
chr7_-_127032741 0.21 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800
zinc finger protein 800
chr16_-_57513657 0.20 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4
docking protein 4
chr17_-_41977964 0.19 ENST00000377184.3
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr8_-_99837856 0.16 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr3_+_180630090 0.16 ENST00000357559.4
ENST00000305586.7
FXR1
fragile X mental retardation, autosomal homolog 1
chrX_-_83442915 0.15 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr12_-_56652111 0.15 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr10_-_104262426 0.15 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr12_-_111021110 0.15 ENST00000354300.3
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr9_+_132815985 0.15 ENST00000372410.3
GPR107
G protein-coupled receptor 107
chr14_-_100070363 0.14 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr15_+_81071684 0.13 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
KIAA1199
chr13_+_42622781 0.12 ENST00000337343.4
ENST00000261491.5
ENST00000379274.2
DGKH
diacylglycerol kinase, eta
chr15_+_91073111 0.12 ENST00000420329.2
CRTC3
CREB regulated transcription coactivator 3
chr20_+_43991668 0.11 ENST00000243918.5
ENST00000426004.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr9_+_98534605 0.11 ENST00000600140.1
DKFZP434H0512
Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512
chr19_+_39616410 0.11 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr6_-_31628512 0.11 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr13_+_22245522 0.10 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr4_+_174292058 0.10 ENST00000296504.3
SAP30
Sin3A-associated protein, 30kDa
chr20_-_30310336 0.10 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr5_-_34916871 0.09 ENST00000382038.2
RAD1
RAD1 homolog (S. pombe)
chr7_-_75988321 0.09 ENST00000307630.3
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chrX_-_77395186 0.09 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr19_-_51523275 0.09 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr1_+_101702417 0.09 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr2_-_178128528 0.09 ENST00000397063.4
ENST00000421929.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr20_-_32308028 0.08 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4
peroxisomal membrane protein 4, 24kDa
chr7_-_98741642 0.07 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr7_+_39663061 0.07 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr16_-_20911641 0.07 ENST00000564349.1
ENST00000324344.4
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chr14_-_82000140 0.07 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr3_+_20081515 0.06 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chrX_+_28605516 0.06 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr2_+_179059365 0.06 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr16_-_70323422 0.06 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr10_+_126490354 0.05 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr4_+_184826418 0.05 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr14_-_55878538 0.05 ENST00000247178.5
ATG14
autophagy related 14
chr1_+_26348259 0.05 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr17_+_38219063 0.05 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA
thyroid hormone receptor, alpha
chrX_-_70288234 0.05 ENST00000276105.3
ENST00000374274.3
SNX12
sorting nexin 12
chr2_+_242255275 0.05 ENST00000391971.2
SEPT2
septin 2
chr12_-_111180644 0.05 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
chr11_+_74459876 0.05 ENST00000299563.4
RNF169
ring finger protein 169
chr18_-_57027194 0.05 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr17_+_4710391 0.04 ENST00000263088.6
ENST00000572940.1
PLD2
phospholipase D2
chr20_+_1099233 0.04 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr11_-_66115032 0.04 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr5_-_180242534 0.04 ENST00000333055.3
ENST00000513431.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr8_-_141645645 0.04 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chrX_-_73834449 0.03 ENST00000332687.6
ENST00000349225.2
RLIM
ring finger protein, LIM domain interacting
chr6_+_4890226 0.03 ENST00000343762.5
CDYL
chromodomain protein, Y-like
chr1_-_205719295 0.03 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr7_+_5322561 0.02 ENST00000396872.3
ENST00000444741.1
ENST00000297195.4
ENST00000406453.3
SLC29A4
solute carrier family 29 (equilibrative nucleoside transporter), member 4
chr5_+_72251793 0.02 ENST00000430046.2
ENST00000341845.6
FCHO2
FCH domain only 2
chr9_-_35754253 0.02 ENST00000436428.2
MSMP
microseminoprotein, prostate associated
chr18_-_45456930 0.02 ENST00000262160.6
ENST00000587269.1
SMAD2
SMAD family member 2
chr18_-_55253989 0.02 ENST00000262093.5
FECH
ferrochelatase
chr5_-_89825328 0.01 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr16_+_69599861 0.01 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr20_+_19997948 0.01 ENST00000310450.4
ENST00000398602.2
NAA20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr9_-_99801592 0.01 ENST00000259470.5
CTSV
cathepsin V
chr22_-_24951054 0.00 ENST00000447813.2
ENST00000402766.1
ENST00000407471.3
ENST00000435822.1
GUCD1
guanylyl cyclase domain containing 1
chr16_+_67596310 0.00 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr9_+_131174024 0.00 ENST00000420034.1
ENST00000372842.1
CERCAM
cerebral endothelial cell adhesion molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGGUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.4 1.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.4 1.7 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.4 1.5 GO:0044691 tooth eruption(GO:0044691)
0.4 1.8 GO:0061032 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.3 1.0 GO:0060129 regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 1.0 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.3 0.8 GO:1903570 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.9 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.2 1.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.7 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.6 GO:0003289 atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.2 0.9 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 1.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.6 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 1.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.2 2.8 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 1.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 1.0 GO:0051414 response to cortisol(GO:0051414)
0.1 0.6 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 1.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 2.9 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 1.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.5 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.6 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 2.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.4 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.0 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0045176 apical protein localization(GO:0045176)
0.0 1.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.9 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0046085 purine nucleoside monophosphate catabolic process(GO:0009128) adenosine metabolic process(GO:0046085)
0.0 1.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.7 GO:0014002 astrocyte development(GO:0014002)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 1.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0003091 renal water homeostasis(GO:0003091)
0.0 2.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0043260 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.3 3.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 1.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.3 GO:0016600 flotillin complex(GO:0016600)
0.1 2.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 6.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.3 1.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 1.3 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.3 2.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 3.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 3.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 1.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.5 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 2.4 GO:0005109 frizzled binding(GO:0005109)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 3.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions