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Illumina Body Map 2, young vs old

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Results for ALX3

Z-value: 0.06

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Transcription factors associated with ALX3

Gene Symbol Gene ID Gene Info
ALX3
ENSG00000156150.6 ALX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX3hg19_v2_chr1_-_110613276_1106133220.048.4e-01Click!

Activity profile of ALX3 motif

Sorted Z-values of ALX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89161432 15.23 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr2_-_89161064 15.01 ENST00000390241.2
IGKJ2
immunoglobulin kappa joining 2
chr2_-_89160770 11.46 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr4_-_25865159 4.81 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr7_-_87342564 4.20 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr2_+_90077680 4.04 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr14_-_106494587 3.83 ENST00000390597.2
IGHV2-5
immunoglobulin heavy variable 2-5
chr14_-_107049312 3.72 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr14_-_106668095 3.66 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr13_-_46742630 3.65 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_17638059 3.61 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr2_-_89385283 3.58 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr2_-_89476644 3.57 ENST00000484817.1
IGKV2-24
immunoglobulin kappa variable 2-24
chr14_+_22670455 3.40 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr2_+_90211643 3.29 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr2_+_135596180 3.23 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr7_+_37723336 3.22 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr12_-_10282742 3.12 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr16_+_12059050 3.04 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_-_92952433 3.01 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr14_+_22465771 2.97 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr20_+_57594309 2.88 ENST00000217133.1
TUBB1
tubulin, beta 1 class VI
chr14_-_106552755 2.86 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr7_+_37723450 2.80 ENST00000447769.1
GPR141
G protein-coupled receptor 141
chr16_+_72088376 2.79 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr12_-_10282836 2.79 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr6_+_160542821 2.78 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr2_+_90043607 2.74 ENST00000462693.1
IGKV2D-24
immunoglobulin kappa variable 2D-24 (non-functional)
chr12_-_10282681 2.67 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr5_-_173217916 2.66 ENST00000523617.1
CTB-43E15.4
CTB-43E15.4
chr12_+_8666126 2.65 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr15_+_58702742 2.62 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr2_+_135596106 2.58 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr16_-_28634874 2.55 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_+_17638041 2.51 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr15_+_94899183 2.46 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr2_+_90273679 2.45 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr3_-_191000172 2.45 ENST00000427544.2
UTS2B
urotensin 2B
chr15_-_20193370 2.43 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr9_-_117111222 2.39 ENST00000374079.4
AKNA
AT-hook transcription factor
chr15_+_96904487 2.38 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr2_-_89340242 2.38 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr19_-_51920952 2.38 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr3_+_121774202 2.34 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr2_+_102615416 2.28 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr2_+_218994002 2.26 ENST00000428565.1
CXCR2
chemokine (C-X-C motif) receptor 2
chr3_+_186692745 2.26 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr2_-_225811747 2.21 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr18_+_29171689 2.19 ENST00000237014.3
TTR
transthyretin
chr21_-_15918618 2.17 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr2_+_68961934 2.14 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr6_+_161123270 2.12 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr9_+_95709733 2.10 ENST00000375482.3
FGD3
FYVE, RhoGEF and PH domain containing 3
chr6_-_138833630 2.10 ENST00000533765.1
NHSL1
NHS-like 1
chr2_+_68961905 2.03 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr19_-_52307357 2.02 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr6_+_160542870 2.00 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr4_+_86525299 1.99 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr18_-_67624160 1.98 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr20_-_7238861 1.97 ENST00000428954.1
RP11-19D2.1
RP11-19D2.1
chr16_-_28608424 1.93 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_+_12059091 1.87 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr19_-_58864848 1.87 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr17_-_64225508 1.81 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_130339710 1.81 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_+_151591422 1.77 ENST00000362032.5
SUCNR1
succinate receptor 1
chr5_+_53686658 1.75 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr2_+_68962014 1.75 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr16_+_31271274 1.74 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr14_-_52436247 1.72 ENST00000597846.1
AL358333.1
HCG2013195; Uncharacterized protein
chr14_+_22977587 1.63 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr3_-_101039402 1.61 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr4_-_48116540 1.59 ENST00000506073.1
TXK
TXK tyrosine kinase
chr4_-_36245561 1.58 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_186353756 1.56 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr1_+_117544366 1.56 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr16_-_28621298 1.54 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr9_+_90112767 1.51 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr18_-_67624412 1.45 ENST00000580335.1
CD226
CD226 molecule
chr16_-_28621312 1.44 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr18_-_67623906 1.41 ENST00000583955.1
CD226
CD226 molecule
chr10_-_99030395 1.40 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr16_-_28608364 1.36 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_150738261 1.34 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr16_-_28621353 1.34 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_+_16500599 1.34 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr9_+_90112590 1.33 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chrX_-_77225135 1.32 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr9_+_90112741 1.31 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr6_+_26402517 1.29 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr17_-_57229155 1.28 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr4_-_164534657 1.27 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr19_-_3557570 1.27 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr6_+_26402465 1.26 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr5_+_176811431 1.25 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr4_-_89442940 1.24 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr1_+_84630645 1.23 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_173217931 1.23 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4
chr12_+_56435637 1.23 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr2_+_103035102 1.20 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr12_+_16500571 1.19 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr2_-_8715616 1.19 ENST00000418358.1
AC011747.3
AC011747.3
chr1_+_84630574 1.19 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_36304201 1.19 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr14_-_78083112 1.17 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr9_-_4666421 1.16 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr11_+_118398178 1.15 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr16_-_30122717 1.15 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr7_-_38315919 1.15 ENST00000390339.1
TRGJP1
T cell receptor gamma joining P1
chr16_-_55866997 1.14 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr10_+_696000 1.14 ENST00000381489.5
PRR26
proline rich 26
chr19_+_50016411 1.12 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr4_+_37455536 1.12 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr2_+_166095898 1.11 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr4_-_19458597 1.10 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr9_-_75488984 1.09 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chr22_+_42834029 1.09 ENST00000428765.1
CTA-126B4.7
CTA-126B4.7
chr10_+_5135981 1.07 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr12_+_16500037 1.04 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr2_-_169887827 1.04 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr4_-_185275104 1.01 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr7_-_142124565 1.01 ENST00000390376.2
TRBV6-8
T cell receptor beta variable 6-8
chr18_-_44181442 1.00 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr10_-_90611566 1.00 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr9_+_90112117 0.99 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr9_-_115095123 0.99 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr4_+_71859156 0.98 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr2_-_101925055 0.97 ENST00000295317.3
RNF149
ring finger protein 149
chr20_-_50722183 0.97 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr8_+_92261516 0.97 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr1_+_186265399 0.95 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr11_-_62521614 0.95 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr5_+_136070614 0.95 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr12_+_15699286 0.94 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr19_+_50016610 0.93 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr8_-_623547 0.93 ENST00000522893.1
ERICH1
glutamate-rich 1
chr5_-_98262240 0.90 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr11_+_327171 0.89 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr13_+_78315295 0.89 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr15_+_64680003 0.88 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr7_-_144435985 0.88 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr13_+_78315348 0.87 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr20_-_33735070 0.87 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr1_+_225600404 0.87 ENST00000366845.2
AC092811.1
AC092811.1
chr16_-_28937027 0.86 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr4_+_80584903 0.86 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr11_+_35201826 0.86 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr1_-_24126051 0.86 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr6_-_32095968 0.85 ENST00000375203.3
ENST00000375201.4
ATF6B
activating transcription factor 6 beta
chr7_-_142251148 0.85 ENST00000390360.3
TRBV6-4
T cell receptor beta variable 6-4
chr5_+_150639360 0.84 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr8_-_93978216 0.84 ENST00000517751.1
ENST00000524107.1
TRIQK
triple QxxK/R motif containing
chr1_+_115572415 0.84 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr6_-_7313381 0.83 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1
signal sequence receptor, alpha
chr1_+_66820058 0.82 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr14_+_22947861 0.80 ENST00000390482.1
TRAJ57
T cell receptor alpha joining 57
chr4_+_95128748 0.78 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_-_36515177 0.78 ENST00000229812.7
STK38
serine/threonine kinase 38
chr3_+_45927994 0.78 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr6_+_78400375 0.76 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr14_+_55494323 0.75 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr8_-_93978309 0.75 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr18_+_29027696 0.75 ENST00000257189.4
DSG3
desmoglein 3
chr5_-_20575959 0.74 ENST00000507958.1
CDH18
cadherin 18, type 2
chr8_-_93978357 0.73 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr3_+_138340049 0.72 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr15_+_58724184 0.72 ENST00000433326.2
LIPC
lipase, hepatic
chr6_+_26440700 0.72 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr2_+_102953608 0.71 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr15_+_48483736 0.71 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr5_-_94417314 0.71 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_93978333 0.71 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr12_-_10022735 0.70 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr17_-_38821373 0.70 ENST00000394052.3
KRT222
keratin 222
chr5_-_94417186 0.70 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_-_24126023 0.69 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr4_+_86699834 0.69 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr12_+_66582919 0.68 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr7_-_111424506 0.68 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr4_+_26324474 0.67 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_120243545 0.67 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr3_+_138340067 0.65 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr14_+_39736582 0.65 ENST00000556148.1
ENST00000348007.3
CTAGE5
CTAGE family, member 5
chr5_+_96840389 0.64 ENST00000504012.1
RP11-1E3.1
RP11-1E3.1
chr17_-_39191107 0.64 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr1_+_28261533 0.63 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr7_+_150020363 0.63 ENST00000359623.4
ENST00000493307.1
LRRC61
leucine rich repeat containing 61
chr5_+_66300464 0.63 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_-_295730 0.63 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr9_-_115095229 0.61 ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chr6_+_28317685 0.60 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr11_-_71823266 0.59 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr8_-_93978346 0.58 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr11_+_46193466 0.57 ENST00000533793.1
RP11-702F3.3
RP11-702F3.3
chrX_+_56100757 0.57 ENST00000433279.1
AL353698.1
Uncharacterized protein
chrX_+_108779004 0.54 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chrX_+_107288280 0.54 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr12_-_118796910 0.53 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr10_-_74283694 0.52 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
MICU1
mitochondrial calcium uptake 1
chr12_+_104337515 0.52 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
1.0 3.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.9 2.8 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.8 5.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.8 4.8 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.8 2.3 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.7 2.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.7 4.8 GO:0048241 epinephrine transport(GO:0048241)
0.6 5.4 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.6 2.3 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.5 2.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.4 8.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.4 1.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.4 2.3 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.4 10.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.4 1.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.3 1.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.3 0.9 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.8 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.3 1.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 2.4 GO:0097338 response to clozapine(GO:0097338)
0.2 1.6 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 3.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 3.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.8 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 0.9 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.2 5.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 0.9 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 1.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.2 0.9 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2 1.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.5 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.2 26.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 3.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.1 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 2.1 GO:0097475 motor neuron migration(GO:0097475)
0.1 2.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.7 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 1.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.5 GO:0019388 galactose catabolic process(GO:0019388)
0.1 2.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.7 GO:0060847 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 2.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.9 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.8 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 35.2 GO:0002250 adaptive immune response(GO:0002250)
0.1 1.0 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.4 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 1.0 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.5 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 2.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 1.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.7 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.8 GO:0033189 response to vitamin A(GO:0033189)
0.0 1.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0035973 aggrephagy(GO:0035973)
0.0 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.2 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:0050776 regulation of immune response(GO:0050776)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 1.6 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 2.9 GO:0051225 spindle assembly(GO:0051225)
0.0 2.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 1.0 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 1.7 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 0.8 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 1.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 1.3 GO:0036021 endolysosome lumen(GO:0036021)
0.1 6.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 3.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 5.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 1.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 2.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 2.3 GO:0042629 mast cell granule(GO:0042629)
0.0 5.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 5.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 4.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 2.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 3.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 2.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 10.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.2 4.8 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.7 2.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.7 4.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.5 2.8 GO:0030492 hemoglobin binding(GO:0030492)
0.5 2.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.4 2.1 GO:0019770 IgG receptor activity(GO:0019770)
0.4 1.5 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.4 2.3 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.4 1.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.3 1.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 1.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3 1.9 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.3 1.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 1.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 2.0 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.2 0.7 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 0.7 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 1.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 2.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 8.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 1.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 3.6 GO:0043295 glutathione binding(GO:0043295)
0.2 3.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 1.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.0 GO:0050733 RS domain binding(GO:0050733)
0.1 29.4 GO:0003823 antigen binding(GO:0003823)
0.1 8.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.7 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.5 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 2.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 5.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 5.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.9 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 1.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 2.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 1.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0000150 recombinase activity(GO:0000150)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 2.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 5.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 3.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.0 5.0 GO:0051020 GTPase binding(GO:0051020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 5.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 5.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 3.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 4.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 7.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 10.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 5.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 5.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 3.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 3.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 4.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 9.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling