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Illumina Body Map 2, young vs old

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Results for ARID5A

Z-value: 0.20

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Transcription factors associated with ARID5A

Gene Symbol Gene ID Gene Info
ENSG00000196843.11 AT-rich interaction domain 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARID5Ahg19_v2_chr2_+_97202480_972024990.364.1e-02Click!

Activity profile of ARID5A motif

Sorted Z-values of ARID5A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_217724767 4.67 ENST00000236979.2
transition protein 1 (during histone to protamine replacement)
chr6_-_49834240 3.72 ENST00000335847.4
cysteine-rich secretory protein 1
chr6_-_49834209 3.63 ENST00000507853.1
cysteine-rich secretory protein 1
chr3_-_150421728 3.45 ENST00000295910.6
ENST00000491361.1
family with sequence similarity 194, member A
chr4_-_177116772 3.34 ENST00000280191.2
spermatogenesis associated 4
chr1_+_40713573 3.20 ENST00000372766.3
transmembrane and coiled-coil domains 2
chr8_+_24298531 3.16 ENST00000175238.6
ADAM metallopeptidase domain 7
chr7_+_142031986 2.99 ENST00000547918.2
T cell receptor beta variable 7-1 (non-functional)
chr8_+_24298597 2.79 ENST00000380789.1
ADAM metallopeptidase domain 7
chr18_-_61329118 2.56 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr2_+_152214098 2.50 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr5_+_159848807 2.45 ENST00000352433.5
pituitary tumor-transforming 1
chr16_-_11375179 2.40 ENST00000312511.3
protamine 1
chr5_+_159848854 2.40 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr11_+_61976137 2.36 ENST00000244930.4
secretoglobin, family 2A, member 1
chr11_-_26588634 2.30 ENST00000436318.2
ENST00000281268.8
mucin 15, cell surface associated
chrX_+_37850026 2.09 ENST00000341016.3
chromosome X open reading frame 27
chr7_-_38339890 2.06 ENST00000390341.2
T cell receptor gamma variable 10 (non-functional)
chr1_-_76398077 2.02 ENST00000284142.6
ankyrin repeat and SOCS box containing 17
chrX_+_36053908 1.95 ENST00000378660.2
calponin homology domain containing 2
chr3_-_150421752 1.89 ENST00000498386.1
family with sequence similarity 194, member A
chr10_+_127661942 1.88 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chrX_+_107288239 1.86 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr16_+_86229728 1.86 ENST00000601250.1
long intergenic non-protein coding RNA 1082
chr8_+_24298438 1.85 ENST00000441335.2
ADAM metallopeptidase domain 7
chr20_+_31870927 1.83 ENST00000253354.1
BPI fold containing family B, member 1
chr18_-_69449517 1.82 ENST00000584810.1
Uncharacterized protein
chr15_+_45248880 1.80 ENST00000340827.3
chromosome 15 open reading frame 43
chr3_-_107596910 1.78 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chrX_+_27608490 1.77 ENST00000451261.2
DDB1 and CUL4 associated factor 8-like 2
chr10_-_23528745 1.77 ENST00000376501.5
chromosome 10 open reading frame 115
chrX_+_36246735 1.76 ENST00000378653.3
chromosome X open reading frame 30
chr5_-_59668541 1.74 ENST00000514552.1
phosphodiesterase 4D, cAMP-specific
chr5_-_131879205 1.71 ENST00000231454.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr19_-_42947121 1.71 ENST00000601181.1
chemokine (C-X-C motif) ligand 17
chr2_+_79252822 1.70 ENST00000272324.5
regenerating islet-derived 3 gamma
chrX_+_107288280 1.69 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr1_-_99999571 1.67 ENST00000438829.2
RP11-413P11.1
chr2_+_74011316 1.67 ENST00000409561.1
chromosome 2 open reading frame 78
chr13_+_75126978 1.67 ENST00000596240.1
ENST00000451336.2
long intergenic non-protein coding RNA 347
chr2_+_149974684 1.66 ENST00000450639.1
LY6/PLAUR domain containing 6B
chr1_+_94798754 1.65 ENST00000418242.1
RP11-148B18.3
chr2_+_79252804 1.65 ENST00000393897.2
regenerating islet-derived 3 gamma
chr9_-_34381536 1.64 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
chromosome 9 open reading frame 24
chr9_-_34381511 1.60 ENST00000379124.1
chromosome 9 open reading frame 24
chr10_+_118083919 1.60 ENST00000333254.3
coiled-coil domain containing 172
chr6_-_49931818 1.59 ENST00000322066.3
defensin, beta 114
chr11_-_102595512 1.56 ENST00000438475.2
matrix metallopeptidase 8 (neutrophil collagenase)
chr5_-_156593273 1.56 ENST00000302938.4
family with sequence similarity 71, member B
chrX_+_79675965 1.56 ENST00000308293.5
family with sequence similarity 46, member D
chr10_+_32856764 1.54 ENST00000375030.2
ENST00000375028.3
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr7_-_91808441 1.53 ENST00000437357.1
ENST00000458448.1
leucine-rich repeats and death domain containing 1
chr12_+_85430110 1.53 ENST00000393212.3
ENST00000393217.2
leucine-rich repeats and IQ motif containing 1
chr3_-_167191814 1.52 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr11_-_125648690 1.52 ENST00000436890.2
ENST00000358524.3
prostate and testis expressed 2
chr20_-_5426332 1.51 ENST00000420529.1
long intergenic non-protein coding RNA 658
chrX_+_55246771 1.50 ENST00000289619.5
ENST00000374955.3
P antigen family, member 5 (prostate associated)
chr11_+_60102304 1.50 ENST00000300182.4
membrane-spanning 4-domains, subfamily A, member 6E
chr9_-_23779367 1.50 ENST00000440102.1
ELAV like neuron-specific RNA binding protein 2
chr1_-_213020991 1.47 ENST00000332912.3
chromosome 1 open reading frame 227
chrX_+_107288197 1.45 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr11_+_60197040 1.45 ENST00000300190.2
membrane-spanning 4-domains, subfamily A, member 5
chr20_+_17680587 1.42 ENST00000427254.1
ENST00000377805.3
barrier to autointegration factor 2
chr1_+_158815588 1.41 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chrX_+_36065053 1.40 ENST00000313548.4
calponin homology domain containing 2
chr10_-_30918669 1.40 ENST00000375318.2
lysozyme-like 2
chr6_-_49712147 1.39 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr8_-_57472154 1.39 ENST00000499425.1
ENST00000523664.1
ENST00000518943.1
ENST00000524338.1
long intergenic non-protein coding RNA 968
chrX_+_36254051 1.39 ENST00000378657.4
chromosome X open reading frame 30
chr13_+_43355732 1.38 ENST00000313851.1
family with sequence similarity 216, member B
chr7_+_16566449 1.37 ENST00000401542.2
leucine rich repeat containing 72
chr1_-_89736434 1.37 ENST00000370459.3
guanylate binding protein 5
chr15_+_22368478 1.36 ENST00000332663.2
olfactory receptor, family 4, subfamily M, member 2
chr6_+_139135648 1.34 ENST00000541398.1
epithelial cell transforming sequence 2 oncogene-like
chr4_+_71248795 1.34 ENST00000304915.3
submaxillary gland androgen regulated protein 3B
chr1_-_85358850 1.34 ENST00000370611.3
lysophosphatidic acid receptor 3
chr16_-_52061283 1.34 ENST00000566314.1
chromosome 16 open reading frame 97
chr13_+_43355683 1.31 ENST00000537894.1
family with sequence similarity 216, member B
chr6_+_132455526 1.31 ENST00000443303.1
long intergenic non-protein coding RNA 1013
chr19_+_56368803 1.30 ENST00000587891.1
NLR family, pyrin domain containing 4
chr4_+_68424434 1.29 ENST00000265404.2
ENST00000396225.1
signal transducing adaptor family member 1
chr8_-_19102999 1.27 ENST00000517949.1
RP11-1080G15.1
chr16_-_58328923 1.26 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
protease, serine, 54
chr2_-_69180083 1.26 ENST00000328895.4
gastrokine 2
chr3_+_26735991 1.26 ENST00000456208.2
leucine rich repeat containing 3B
chr8_+_36641842 1.25 ENST00000523973.1
ENST00000399881.3
potassium channel, subfamily U, member 1
chr4_+_94125100 1.24 ENST00000512631.1
glutamate receptor, ionotropic, delta 2
chr12_-_45269430 1.23 ENST00000395487.2
NEL-like 2 (chicken)
chr9_-_24545850 1.22 ENST00000543880.2
ENST00000418122.1
IZUMO family member 3
chr10_-_22498950 1.21 ENST00000422359.2
endogenous Bornavirus-like nucleoprotein 1
chr1_+_170904612 1.21 ENST00000367759.4
ENST00000367758.3
maestro heat-like repeat family member 9
chr3_+_14716606 1.18 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
chromosome 3 open reading frame 20
chr5_-_61031495 1.18 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
chr3_+_94657016 1.18 ENST00000462219.1
long intergenic non-protein coding RNA 879
chr10_-_75118471 1.17 ENST00000340329.3
tetratricopeptide repeat domain 18
chr20_+_55904815 1.17 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11 meiotic protein covalently bound to DSB
chr12_+_8608522 1.17 ENST00000382073.3
C-type lectin domain family 6, member A
chr17_+_61473104 1.16 ENST00000583016.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr17_-_46262541 1.16 ENST00000579336.1
src kinase associated phosphoprotein 1
chr6_-_49712072 1.15 ENST00000423399.2
cysteine-rich secretory protein 3
chr7_+_142000747 1.15 ENST00000455382.2
T cell receptor beta variable 2
chr4_-_122148620 1.14 ENST00000509841.1
TNFAIP3 interacting protein 3
chr9_-_107299137 1.14 ENST00000374781.2
olfactory receptor, family 13, subfamily C, member 3
chr3_-_157221128 1.13 ENST00000392833.2
ENST00000362010.2
ventricular zone expressed PH domain-containing 1
chr20_+_17680599 1.13 ENST00000246090.5
barrier to autointegration factor 2
chr11_+_60282862 1.12 ENST00000378186.2
ENST00000378185.2
ENST00000437058.2
ENST00000527948.1
membrane-spanning 4-domains, subfamily A, member 13
chr15_-_41522889 1.11 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
exonuclease 3'-5' domain containing 1
chr6_-_136571400 1.10 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
mitochondrial fission regulator 2
chr19_-_56704421 1.10 ENST00000358992.3
zinc finger and SCAN domain containing 5B
chr7_-_48068671 1.08 ENST00000297325.4
Sad1 and UNC84 domain containing 3
chr6_+_15401075 1.07 ENST00000541660.1
jumonji, AT rich interactive domain 2
chr6_-_130543958 1.07 ENST00000437477.2
ENST00000439090.2
sterile alpha motif domain containing 3
chr7_-_16921601 1.06 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
anterior gradient 3
chr1_-_149459549 1.06 ENST00000369175.3
family with sequence similarity 72, member C
chr22_-_50523843 1.05 ENST00000535444.1
ENST00000431262.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_+_130279178 1.04 ENST00000358511.6
ENST00000453409.2
collagen, type VI, alpha 6
chr2_-_166930131 1.04 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
sodium channel, voltage-gated, type I, alpha subunit
chr6_+_132455118 1.03 ENST00000458028.1
long intergenic non-protein coding RNA 1013
chr6_-_49712091 1.03 ENST00000371159.4
cysteine-rich secretory protein 3
chr5_+_54398463 1.02 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr11_+_71544246 1.01 ENST00000328698.1
defensin, beta 108B
chr12_+_9980113 1.01 ENST00000537723.1
killer cell lectin-like receptor subfamily F, member 1
chr12_+_9980069 0.99 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
killer cell lectin-like receptor subfamily F, member 1
chr12_+_10460549 0.99 ENST00000543420.1
ENST00000543777.1
killer cell lectin-like receptor subfamily D, member 1
chr16_+_31366536 0.99 ENST00000562522.1
integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_+_77333117 0.99 ENST00000477717.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr14_+_39944025 0.98 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr12_+_81664424 0.98 ENST00000549161.1
ENST00000550138.1
RP11-121G22.3
chr19_+_55014085 0.98 ENST00000351841.2
leukocyte-associated immunoglobulin-like receptor 2
chr6_-_49712123 0.97 ENST00000263045.4
cysteine-rich secretory protein 3
chr16_-_58328884 0.97 ENST00000569079.1
protease, serine, 54
chr12_-_4758159 0.97 ENST00000545990.2
A kinase (PRKA) anchor protein 3
chr2_-_69180012 0.97 ENST00000481498.1
gastrokine 2
chr5_-_131892501 0.97 ENST00000450655.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr11_+_60197069 0.96 ENST00000528905.1
ENST00000528093.1
membrane-spanning 4-domains, subfamily A, member 5
chrX_+_8432871 0.96 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
variable charge, X-linked 3B
chr16_-_58328870 0.95 ENST00000543437.1
protease, serine, 54
chr10_+_97759848 0.94 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
coiled-coil and C2 domain containing 2B
chr14_-_25045446 0.94 ENST00000216336.2
cathepsin G
chr10_+_97709725 0.94 ENST00000472454.2
Protein LOC100652732
chr10_+_47746929 0.92 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
annexin A8-like 2
Protein LOC100996760
chr2_-_39456673 0.90 ENST00000378803.1
ENST00000395035.3
cyclin-dependent kinase-like 4
chr14_+_20295608 0.88 ENST00000568211.1
ENST00000315947.1
olfactory receptor, family 4, subfamily N, member 2
chr5_+_57787254 0.88 ENST00000502276.1
ENST00000396776.2
ENST00000511930.1
GRB2-binding adaptor protein, transmembrane
chr10_+_106113515 0.88 ENST00000369704.3
ENST00000312902.5
coiled-coil domain containing 147
chrX_+_55246818 0.87 ENST00000374952.1
P antigen family, member 5 (prostate associated)
chr22_-_32766972 0.87 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr8_+_7682694 0.87 ENST00000335186.2
defensin, beta 106A
chr6_+_31707725 0.87 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
mutS homolog 5
chr12_+_40787194 0.86 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr7_-_38295997 0.86 ENST00000390334.1
T cell receptor gamma joining P2
chr3_-_108672742 0.85 ENST00000261047.3
guanylate cyclase activator 1C
chr21_+_43823983 0.85 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr14_-_21029090 0.84 ENST00000338904.3
ENST00000554964.1
ENST00000555230.1
ENST00000557068.1
ENST00000404716.3
ENST00000556208.1
ENST00000553541.1
ENST00000429244.2
ENST00000553706.1
ENST00000557209.1
ribonuclease, RNase A family, 9 (non-active)
chr22_-_32767017 0.83 ENST00000400234.1
RFPL3 antisense
chr7_+_50135433 0.83 ENST00000297001.6
chromosome 7 open reading frame 72
chrX_-_142804516 0.83 ENST00000370498.1
SPANX family, member N2
chrX_-_107682702 0.82 ENST00000372216.4
collagen, type IV, alpha 6
chr12_-_45315625 0.81 ENST00000552993.1
NEL-like 2 (chicken)
chrX_+_114423963 0.81 ENST00000424776.3
RNA binding motif protein, X-linked-like 3
chr12_-_15082050 0.81 ENST00000540097.1
endoplasmic reticulum protein 27
chr2_-_46621306 0.81 ENST00000418415.1
AC016912.3
chr1_+_209602771 0.80 ENST00000440276.1
MIR205 host gene (non-protein coding)
chr12_-_45269251 0.80 ENST00000553120.1
NEL-like 2 (chicken)
chr6_-_133055896 0.79 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
vanin 3
chr17_-_71223839 0.79 ENST00000579872.1
ENST00000580032.1
family with sequence similarity 104, member A
chr18_-_19994830 0.79 ENST00000525417.1
cutaneous T-cell lymphoma-associated antigen 1
chr4_+_100737954 0.79 ENST00000296414.7
ENST00000512369.1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr5_-_19988339 0.78 ENST00000382275.1
cadherin 18, type 2
chrX_-_154493791 0.78 ENST00000369454.3
RAB39B, member RAS oncogene family
chr11_-_26744908 0.77 ENST00000533617.1
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr11_+_128563652 0.76 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_133084580 0.76 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
vanin 2
chr20_+_15177480 0.76 ENST00000402914.1
MACRO domain containing 2
chr2_-_208989225 0.75 ENST00000264376.4
crystallin, gamma D
chr2_-_118943930 0.75 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
chr9_+_71357171 0.75 ENST00000440050.1
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr3_+_94657086 0.74 ENST00000463200.1
long intergenic non-protein coding RNA 879
chr2_+_90024732 0.74 ENST00000390268.2
immunoglobulin kappa variable 2D-26
chr22_+_32754139 0.74 ENST00000382088.3
ret finger protein-like 3
chr6_+_26199737 0.73 ENST00000359985.1
histone cluster 1, H2bf
chr12_+_70219052 0.73 ENST00000552032.2
ENST00000547771.2
myelin regulatory factor-like
chr12_-_10542617 0.72 ENST00000240618.6
killer cell lectin-like receptor subfamily K, member 1
chr19_+_55014013 0.71 ENST00000301202.2
leukocyte-associated immunoglobulin-like receptor 2
chr12_-_10607084 0.70 ENST00000408006.3
ENST00000544822.1
ENST00000536188.1
killer cell lectin-like receptor subfamily C, member 1
chr14_+_22788560 0.70 ENST00000390468.1
T cell receptor alpha variable 41
chr15_-_58571445 0.70 ENST00000558231.1
aldehyde dehydrogenase 1 family, member A2
chr1_+_152178320 0.70 ENST00000429352.1
RP11-107M16.2
chr7_+_135710494 0.70 ENST00000440744.2
AC024084.1
chr12_-_10562356 0.69 ENST00000309384.1
killer cell lectin-like receptor subfamily C, member 4
chr8_+_55528627 0.69 ENST00000220676.1
retinitis pigmentosa 1 (autosomal dominant)
chr18_+_61223393 0.69 ENST00000269491.1
ENST00000382768.1
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr22_-_32860427 0.69 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPI fold containing family C
chr22_-_23922448 0.67 ENST00000438703.1
ENST00000330377.2
immunoglobulin lambda-like polypeptide 1
chr17_-_43339453 0.67 ENST00000543122.1
spermatogenesis associated 32
chr2_+_101223490 0.67 ENST00000414647.1
ENST00000424342.1
AC068538.4
chr14_+_56584414 0.67 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr22_-_29457832 0.66 ENST00000216071.4
chromosome 22 open reading frame 31
chr7_-_130066571 0.66 ENST00000492389.1
centrosomal protein 41kDa
chr4_-_90756769 0.66 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)

Network of associatons between targets according to the STRING database.

First level regulatory network of ARID5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.9 2.7 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.7 4.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.6 2.6 GO:0035425 autocrine signaling(GO:0035425)
0.5 1.4 GO:0072616 interleukin-18 secretion(GO:0072616)
0.4 1.3 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.4 2.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.4 7.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 1.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 0.7 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 0.7 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.2 3.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 1.8 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 0.9 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.2 0.8 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 0.5 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) B cell cytokine production(GO:0002368)
0.2 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 4.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 1.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 1.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.7 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 2.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.9 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.9 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 1.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.6 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 1.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0003409 optic cup structural organization(GO:0003409)
0.1 1.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 4.8 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.1 1.9 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 2.5 GO:0030728 ovulation(GO:0030728)
0.1 1.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.7 GO:0035799 ureter maturation(GO:0035799)
0.1 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.5 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:0060369 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 1.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.2 GO:1900275 negative regulation of phospholipase C activity(GO:1900275) regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.6 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 2.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 1.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 2.0 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.4 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 2.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 1.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.6 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.1 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 1.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 3.1 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.5 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.7 GO:0031297 replication fork processing(GO:0031297)
0.0 1.5 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 2.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 4.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.3 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.2 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 1.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.0 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.1 GO:1990923 PET complex(GO:1990923)
0.2 0.6 GO:0097679 other organism cytoplasm(GO:0097679)
0.2 3.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.9 GO:1990742 microvesicle(GO:1990742)
0.1 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 8.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.5 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0032437 cuticular plate(GO:0032437)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 1.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 1.1 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.2 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.9 GO:0032300 mismatch repair complex(GO:0032300)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 1.0 GO:0045178 basal part of cell(GO:0045178)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 1.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.4 2.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.4 2.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 1.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.7 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 1.1 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 1.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 3.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 1.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 2.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.6 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.1 1.5 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 6.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 7.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 9.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 2.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 1.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 4.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.0 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.0 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 15.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 8.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.2 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 4.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 2.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers