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Illumina Body Map 2, young vs old

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Results for AUGGCUU

Z-value: 0.75

Motif logo

miRNA associated with seed AUGGCUU

NamemiRBASE accession
MIMAT0000428
MIMAT0000758

Activity profile of AUGGCUU motif

Sorted Z-values of AUGGCUU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_175223313 7.61 ENST00000359546.4
complexin 2
chr8_+_24772455 5.97 ENST00000433454.2
neurofilament, medium polypeptide
chr9_-_19786926 4.93 ENST00000341998.2
ENST00000286344.3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr9_-_93405352 4.46 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chr6_+_123317116 4.40 ENST00000275162.5
clavesin 2
chrX_+_12156582 4.33 ENST00000380682.1
FERM and PDZ domain containing 4
chr1_+_181452678 4.20 ENST00000367570.1
ENST00000526775.1
ENST00000357570.5
ENST00000358338.5
ENST00000367567.4
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr5_-_45696253 4.20 ENST00000303230.4
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr19_+_589893 4.12 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr15_+_27111510 4.11 ENST00000335625.5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr19_-_17799008 3.97 ENST00000519716.2
unc-13 homolog A (C. elegans)
chr3_+_49591881 3.75 ENST00000296452.4
bassoon presynaptic cytomatrix protein
chr2_+_166095898 3.73 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr12_-_14133053 3.61 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chrX_-_154493791 3.55 ENST00000369454.3
RAB39B, member RAS oncogene family
chr12_+_79258547 3.47 ENST00000457153.2
synaptotagmin I
chr1_+_209757051 3.39 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
calcium/calmodulin-dependent protein kinase IG
chr4_+_47033345 3.35 ENST00000295454.3
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr5_-_160973649 3.29 ENST00000393959.1
ENST00000517547.1
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr6_-_99797522 3.25 ENST00000389677.5
failed axon connections homolog (Drosophila)
chr15_+_59730348 3.19 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr7_+_31092076 3.16 ENST00000304166.4
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
chr17_-_9929581 3.05 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr15_+_91643442 2.95 ENST00000394232.1
synaptic vesicle glycoprotein 2B
chr5_-_136834982 2.91 ENST00000510689.1
ENST00000394945.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr2_-_2334888 2.90 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr11_-_118047376 2.89 ENST00000278947.5
sodium channel, voltage-gated, type II, beta subunit
chr2_-_40679186 2.85 ENST00000406785.2
solute carrier family 8 (sodium/calcium exchanger), member 1
chr16_+_58497567 2.82 ENST00000258187.5
NDRG family member 4
chr9_+_77112244 2.72 ENST00000376896.3
RAR-related orphan receptor B
chr19_-_55954230 2.70 ENST00000376325.4
shisa family member 7
chr10_-_1779663 2.67 ENST00000381312.1
adenosine deaminase, RNA-specific, B2 (non-functional)
chr19_-_38714847 2.53 ENST00000420980.2
ENST00000355526.4
D4, zinc and double PHD fingers family 1
chr8_+_104831472 2.50 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chr6_+_96463840 2.47 ENST00000302103.5
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr17_-_78450398 2.45 ENST00000306773.4
neuronal pentraxin I
chrX_-_24690771 2.42 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chr1_+_159141397 2.39 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
cell adhesion molecule 3
chr11_+_62475130 2.39 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr7_+_30174426 2.38 ENST00000324453.8
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_-_229478236 2.36 ENST00000366687.1
ENST00000452552.1
centriole, cilia and spindle-associated protein
chr16_-_755819 2.33 ENST00000397621.1
F-box and leucine-rich repeat protein 16
chr5_+_112043186 2.31 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
adenomatous polyposis coli
chr1_+_107683644 2.30 ENST00000370067.1
netrin G1
chr8_-_27115903 2.30 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr6_+_24126350 2.27 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr18_+_72201829 2.26 ENST00000582365.1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr8_+_1449532 2.22 ENST00000421627.2
discs, large (Drosophila) homolog-associated protein 2
chr17_-_7832753 2.19 ENST00000303790.2
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr20_-_9819479 2.17 ENST00000378423.1
ENST00000353224.5
p21 protein (Cdc42/Rac)-activated kinase 7
chr3_-_56502375 2.16 ENST00000288221.6
ELKS/RAB6-interacting/CAST family member 2
chr19_-_51141196 2.12 ENST00000338916.4
synaptotagmin III
chr6_+_138483058 2.11 ENST00000251691.4
KIAA1244
chr15_-_48470558 2.00 ENST00000324324.7
myelin expression factor 2
chr13_-_67804445 1.82 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
protocadherin 9
chr12_+_111471828 1.81 ENST00000261726.6
cut-like homeobox 2
chr5_-_147162078 1.81 ENST00000507386.1
janus kinase and microtubule interacting protein 2
chr6_+_72596604 1.78 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
regulating synaptic membrane exocytosis 1
chr1_+_42846443 1.78 ENST00000410070.2
ENST00000431473.3
ribosomal modification protein rimK-like family member A
chr2_+_155554797 1.75 ENST00000295101.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr17_+_11144580 1.72 ENST00000441885.3
ENST00000432116.3
ENST00000409168.3
shisa family member 6
chr17_+_40834580 1.71 ENST00000264638.4
contactin associated protein 1
chr3_+_159943362 1.69 ENST00000326474.3
chromosome 3 open reading frame 80
chr20_+_42875887 1.68 ENST00000342560.5
ganglioside induced differentiation associated protein 1-like 1
chrX_+_152783131 1.65 ENST00000349466.2
ENST00000370186.1
ATPase, Ca++ transporting, plasma membrane 3
chr4_-_819901 1.64 ENST00000304062.6
complexin 1
chr1_+_161228517 1.62 ENST00000504449.1
Purkinje cell protein 4 like 1
chr8_-_133493200 1.60 ENST00000388996.4
potassium voltage-gated channel, KQT-like subfamily, member 3
chr12_+_108525517 1.59 ENST00000332082.4
WSC domain containing 2
chr7_-_86688990 1.57 ENST00000450689.2
KIAA1324-like
chr17_+_56833184 1.56 ENST00000308249.2
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr16_+_8768422 1.55 ENST00000268251.8
ENST00000564714.1
4-aminobutyrate aminotransferase
chr7_+_140774032 1.53 ENST00000565468.1
transmembrane protein 178B
chr1_+_171810606 1.50 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
dynamin 3
chr18_+_55018044 1.50 ENST00000324000.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr19_-_2702681 1.45 ENST00000382159.3
guanine nucleotide binding protein (G protein), gamma 7
chr5_+_82767284 1.43 ENST00000265077.3
versican
chr4_+_57371509 1.43 ENST00000360096.2
ADP-ribosylation factor-like 9
chr1_+_162039558 1.40 ENST00000530878.1
ENST00000361897.5
nitric oxide synthase 1 (neuronal) adaptor protein
chr18_+_905104 1.39 ENST00000579794.1
adenylate cyclase activating polypeptide 1 (pituitary)
chrX_-_13956737 1.37 ENST00000454189.2
glycoprotein M6B
chr11_+_121322832 1.37 ENST00000260197.7
sortilin-related receptor, L(DLR class) A repeats containing
chr18_+_32558208 1.34 ENST00000436190.2
microtubule-associated protein, RP/EB family, member 2
chr7_-_87849340 1.32 ENST00000419179.1
ENST00000265729.2
sorcin
chr12_+_101188547 1.30 ENST00000546991.1
ENST00000392979.3
anoctamin 4
chr6_+_11094266 1.27 ENST00000416247.2
small integral membrane protein 13
chr4_-_87281224 1.25 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr1_-_233431458 1.25 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr7_-_32338917 1.23 ENST00000396193.1
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr1_-_155942086 1.22 ENST00000368315.4
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr2_-_47798044 1.20 ENST00000327876.4
potassium channel, subfamily K, member 12
chr11_-_1593150 1.19 ENST00000397374.3
dual specificity phosphatase 8
chr20_-_48099182 1.18 ENST00000371741.4
potassium voltage-gated channel, Shab-related subfamily, member 1
chr10_-_62149433 1.14 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_38259540 1.14 ENST00000397631.3
mannosidase, endo-alpha-like
chr4_+_93225550 1.13 ENST00000282020.4
glutamate receptor, ionotropic, delta 2
chr21_-_39288743 1.13 ENST00000609713.1
potassium inwardly-rectifying channel, subfamily J, member 6
chr1_-_37499726 1.13 ENST00000373091.3
ENST00000373093.4
glutamate receptor, ionotropic, kainate 3
chr4_+_99182593 1.10 ENST00000508213.1
ENST00000408927.3
ENST00000514122.1
ENST00000453712.2
ENST00000511212.1
ENST00000408900.3
ENST00000339360.5
RAP1, GTP-GDP dissociation stimulator 1
chr11_-_13484713 1.09 ENST00000526841.1
ENST00000529708.1
ENST00000278174.5
ENST00000528120.1
BTB (POZ) domain containing 10
chr2_-_213403565 1.08 ENST00000342788.4
ENST00000436443.1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr2_-_175351744 1.06 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
G protein-coupled receptor 155
chr10_+_105253661 1.05 ENST00000369780.4
neuralized E3 ubiquitin protein ligase 1
chr19_-_44143939 1.04 ENST00000222374.2
cell adhesion molecule 4
chr11_-_119599794 1.03 ENST00000264025.3
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chrX_+_37430822 1.02 ENST00000378621.3
ENST00000378619.3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr8_+_94929168 1.01 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_-_117186946 1.00 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr4_-_42659102 1.00 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr22_-_37099555 0.97 ENST00000300105.6
calcium channel, voltage-dependent, gamma subunit 2
chr7_-_117513540 0.97 ENST00000160373.3
cortactin binding protein 2
chr15_-_34628951 0.95 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr17_-_8066250 0.94 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr1_-_72748417 0.94 ENST00000357731.5
neuronal growth regulator 1
chr6_-_11044509 0.90 ENST00000354666.3
ELOVL fatty acid elongase 2
chr7_+_152456829 0.89 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ARP3 actin-related protein 3 homolog B (yeast)
chr8_-_18871159 0.89 ENST00000327040.8
ENST00000440756.2
pleckstrin and Sec7 domain containing 3
chr8_-_4852218 0.87 ENST00000400186.3
ENST00000602723.1
CUB and Sushi multiple domains 1
chr11_+_20620946 0.86 ENST00000525748.1
solute carrier family 6 (neurotransmitter transporter), member 5
chr17_-_56494713 0.85 ENST00000407977.2
ring finger protein 43
chr7_-_71801980 0.82 ENST00000329008.5
calneuron 1
chr1_-_101360331 0.80 ENST00000416479.1
ENST00000370113.3
exostosin-like glycosyltransferase 2
chr12_-_25102252 0.79 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr9_-_127905736 0.77 ENST00000336505.6
ENST00000373549.4
suppressor of cancer cell invasion
chr9_-_73736511 0.76 ENST00000377110.3
ENST00000377111.2
transient receptor potential cation channel, subfamily M, member 3
chr11_-_95657231 0.73 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
myotubularin related protein 2
chrX_+_37865804 0.73 ENST00000297875.2
ENST00000357972.5
synaptotagmin-like 5
chr1_-_166944652 0.73 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
immunoglobulin-like domain containing receptor 2
chr2_-_175499294 0.73 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr7_-_75988321 0.71 ENST00000307630.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr9_+_15553055 0.71 ENST00000380701.3
coiled-coil domain containing 171
chr10_+_103113802 0.70 ENST00000370187.3
beta-transducin repeat containing E3 ubiquitin protein ligase
chr3_+_138066539 0.69 ENST00000289104.4
muscle RAS oncogene homolog
chr6_+_87865262 0.69 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr21_-_32931290 0.68 ENST00000286827.3
T-cell lymphoma invasion and metastasis 1
chr13_+_98086445 0.68 ENST00000245304.4
RAP2A, member of RAS oncogene family
chr20_+_57766075 0.68 ENST00000371030.2
zinc finger protein 831
chr12_+_104850740 0.67 ENST00000547956.1
ENST00000549260.1
ENST00000303694.5
carbohydrate (chondroitin 4) sulfotransferase 11
chr10_+_76586348 0.67 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr8_-_89339705 0.67 ENST00000286614.6
matrix metallopeptidase 16 (membrane-inserted)
chr18_+_32073253 0.66 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
dystrobrevin, alpha
chr6_+_33387868 0.66 ENST00000418600.2
synaptic Ras GTPase activating protein 1
chrX_-_53310791 0.65 ENST00000375365.2
IQ motif and Sec7 domain 2
chr8_-_145559943 0.65 ENST00000332135.4
scratch family zinc finger 1
chr3_-_119813264 0.65 ENST00000264235.8
glycogen synthase kinase 3 beta
chr18_+_8717369 0.62 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA family member 2
chr3_+_142442841 0.61 ENST00000476941.1
ENST00000273482.6
transient receptor potential cation channel, subfamily C, member 1
chr7_-_83824169 0.60 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr16_-_47177874 0.59 ENST00000562435.1
neuropilin (NRP) and tolloid (TLL)-like 2
chr1_-_33338076 0.58 ENST00000496770.1
fibronectin type III domain containing 5
chr5_+_75378997 0.58 ENST00000502798.2
synaptic vesicle glycoprotein 2C
chr18_+_59854480 0.58 ENST00000256858.6
ENST00000398130.2
KIAA1468
chrX_+_152953505 0.58 ENST00000253122.5
solute carrier family 6 (neurotransmitter transporter), member 8
chr1_-_40137710 0.57 ENST00000235628.1
5'-nucleotidase, cytosolic IA
chr10_-_89577910 0.57 ENST00000308448.7
ENST00000541004.1
ATPase family, AAA domain containing 1
chr1_+_203595903 0.55 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATPase, Ca++ transporting, plasma membrane 4
chr1_+_97187318 0.55 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
polypyrimidine tract binding protein 2
chr11_-_94964354 0.55 ENST00000536441.1
sestrin 3
chr13_+_80055284 0.55 ENST00000218652.7
Nedd4 family interacting protein 2
chr14_+_23775971 0.53 ENST00000250405.5
BCL2-like 2
chr11_-_77532050 0.53 ENST00000308488.6
remodeling and spacing factor 1
chr12_+_56367697 0.53 ENST00000553116.1
ENST00000360299.5
ENST00000548068.1
ENST00000549915.1
ENST00000551459.1
ENST00000448789.2
RAB5B, member RAS oncogene family
chr9_-_79520989 0.53 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr2_-_129076151 0.53 ENST00000259241.6
heparan sulfate 6-O-sulfotransferase 1
chr12_-_58027138 0.53 ENST00000341156.4
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr10_+_25463951 0.52 ENST00000376351.3
G protein-coupled receptor 158
chr19_-_40324255 0.51 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr1_-_150208291 0.51 ENST00000533654.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_-_94254821 0.50 ENST00000393140.1
proline rich membrane anchor 1
chr6_-_94129244 0.50 ENST00000369303.4
ENST00000369297.1
EPH receptor A7
chr1_+_110527308 0.49 ENST00000369799.5
adenosylhomocysteinase-like 1
chr15_-_45815005 0.49 ENST00000261867.4
solute carrier family 30 (zinc transporter), member 4
chr12_+_27396901 0.48 ENST00000541191.1
ENST00000389032.3
serine/threonine kinase 38 like
chr2_+_7057523 0.48 ENST00000320892.6
ring finger protein 144A
chrX_+_103411189 0.47 ENST00000493442.1
family with sequence similarity 199, X-linked
chr1_-_231004220 0.47 ENST00000366663.5
chromosome 1 open reading frame 198
chr1_-_154842741 0.46 ENST00000271915.4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr16_-_71758602 0.45 ENST00000568954.1
PH domain and leucine rich repeat protein phosphatase 2
chr10_+_97515409 0.44 ENST00000371207.3
ENST00000543964.1
ectonucleoside triphosphate diphosphohydrolase 1
chr5_-_35230771 0.44 ENST00000342362.5
prolactin receptor
chr11_+_22214708 0.43 ENST00000324559.8
anoctamin 5
chr1_-_166845515 0.43 ENST00000367874.4
transcriptional adaptor 1
chr10_-_99052382 0.43 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr15_-_33360085 0.42 ENST00000334528.9
formin 1
chr3_+_169684553 0.42 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr12_+_4382917 0.40 ENST00000261254.3
cyclin D2
chrX_-_135849484 0.40 ENST00000370620.1
ENST00000535227.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_+_71768043 0.39 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB kinase activator 1B
chr1_-_76076793 0.39 ENST00000370859.3
solute carrier family 44, member 5
chr8_-_143696833 0.39 ENST00000356613.2
activity-regulated cytoskeleton-associated protein
chr3_+_105085734 0.39 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr5_-_36152031 0.38 ENST00000296603.4
LMBR1 domain containing 2
chr12_+_57984965 0.38 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr10_+_99185917 0.37 ENST00000334828.5
phosphoglycerate mutase 1 (brain)
chr17_-_44896047 0.37 ENST00000225512.5
wingless-type MMTV integration site family, member 3
chr11_-_108093329 0.36 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr1_-_71546690 0.35 ENST00000254821.6
zinc finger, RAN-binding domain containing 2
chr15_-_100258029 0.35 ENST00000378904.2
DKFZP779J2370
chr11_+_19138670 0.35 ENST00000446113.2
ENST00000399351.3
zinc finger, DHHC-type containing 13
chr7_+_99613195 0.34 ENST00000324306.6
zinc finger with KRAB and SCAN domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of AUGGCUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.7 4.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.6 7.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.6 3.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.6 4.0 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.5 1.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.5 1.4 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.5 1.4 GO:0090273 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.5 1.4 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4 2.9 GO:0046684 response to pyrethroid(GO:0046684)
0.4 1.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.3 4.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.3 2.4 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 2.9 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.3 5.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 1.5 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 1.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 7.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 6.6 GO:0071420 cellular response to histamine(GO:0071420)
0.3 2.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.3 4.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 1.0 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 1.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 0.7 GO:0033037 polysaccharide localization(GO:0033037)
0.2 1.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 3.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 2.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 4.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.6 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.2 1.0 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 1.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 1.7 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.2 2.5 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 1.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 1.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 3.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 1.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 2.8 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 1.4 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.7 GO:0002175 protein localization to paranode region of axon(GO:0002175) neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.9 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 4.9 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.7 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 4.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 1.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 2.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.8 GO:0007614 short-term memory(GO:0007614)
0.1 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 3.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 3.1 GO:0048665 neuron fate specification(GO:0048665)
0.1 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.7 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 4.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 3.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 4.3 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.7 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 2.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 3.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 1.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 0.7 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 3.7 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.5 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 3.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0008050 courtship behavior(GO:0007619) female courtship behavior(GO:0008050)
0.0 0.5 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.3 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 4.0 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 2.2 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 1.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.7 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.7 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 3.0 GO:0050808 synapse organization(GO:0050808)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0098855 HCN channel complex(GO:0098855)
0.9 9.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.5 8.2 GO:0005883 neurofilament(GO:0005883)
0.5 1.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.4 4.0 GO:0044305 calyx of Held(GO:0044305)
0.4 5.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 0.9 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 1.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.3 1.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 10.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 6.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.2 2.4 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.2 5.7 GO:0033268 node of Ranvier(GO:0033268)
0.2 10.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 2.2 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.7 GO:0033010 paranodal junction(GO:0033010)
0.1 5.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.3 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 1.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.4 GO:0071565 nBAF complex(GO:0071565)
0.1 5.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.1 3.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.1 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 4.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 7.2 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 3.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 6.7 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 3.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 3.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.6 3.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.6 4.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 1.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.5 2.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 1.8 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.4 3.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4 2.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 2.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 3.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 1.5 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 14.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 3.6 GO:0016594 glycine binding(GO:0016594)
0.3 0.8 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.3 1.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 7.5 GO:0050811 GABA receptor binding(GO:0050811)
0.2 2.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 0.9 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 1.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 0.6 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 0.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.7 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 3.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 4.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.8 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 2.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.5 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 3.5 GO:0031489 myosin V binding(GO:0031489)
0.1 1.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 4.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 3.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 3.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 7.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 1.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 4.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0005114 transforming growth factor beta receptor activity, type I(GO:0005025) type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 7.3 GO:0015631 tubulin binding(GO:0015631)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.2 PID REELIN PATHWAY Reelin signaling pathway
0.1 4.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 4.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 6.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 9.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 8.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 3.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 2.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 10.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 6.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation