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Illumina Body Map 2, young vs old

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Results for BRCA1

Z-value: 0.10

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Transcription factors associated with BRCA1

Gene Symbol Gene ID Gene Info
BRCA1
ENSG00000012048.15 BRCA1 DNA repair associated

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BRCA1hg19_v2_chr17_-_41277370_412774190.345.4e-02Click!

Activity profile of BRCA1 motif

Sorted Z-values of BRCA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_41738931 1.04 ENST00000329168.3
ENST00000549132.1
MEOX1
mesenchyme homeobox 1
chr17_-_41739283 1.01 ENST00000393661.2
ENST00000318579.4
MEOX1
mesenchyme homeobox 1
chr14_-_60097524 1.00 ENST00000342503.4
RTN1
reticulon 1
chr14_-_60097297 0.97 ENST00000395090.1
RTN1
reticulon 1
chr2_+_196522032 0.82 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr6_+_12717892 0.76 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr6_-_110797799 0.72 ENST00000456137.2
ENST00000368919.3
ENST00000439654.1
SLC22A16
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr6_+_123100620 0.71 ENST00000368444.3
FABP7
fatty acid binding protein 7, brain
chr19_-_48059113 0.66 ENST00000391901.3
ENST00000314121.4
ENST00000448976.1
ZNF541
zinc finger protein 541
chr2_-_158182322 0.66 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr2_+_196521458 0.65 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr11_+_124789146 0.62 ENST00000408930.5
HEPN1
hepatocellular carcinoma, down-regulated 1
chr19_+_45971246 0.59 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr2_-_158182410 0.58 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr2_+_196521903 0.55 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr4_+_619347 0.54 ENST00000255622.6
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr17_+_74372662 0.51 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr4_+_619386 0.51 ENST00000496514.1
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr12_+_122880045 0.51 ENST00000539034.1
ENST00000535976.1
RP11-450K4.1
RP11-450K4.1
chr8_-_116681221 0.48 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr6_-_110797591 0.47 ENST00000424139.1
ENST00000437378.1
SLC22A16
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr2_+_196521845 0.46 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr18_-_49557 0.44 ENST00000308911.6
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr6_-_110797642 0.42 ENST00000434949.1
SLC22A16
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr10_-_95209 0.40 ENST00000332708.5
ENST00000309812.4
TUBB8
tubulin, beta 8 class VIII
chr10_+_122610853 0.39 ENST00000604585.1
WDR11
WD repeat domain 11
chr8_-_16859690 0.38 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr9_-_43133544 0.38 ENST00000254835.2
ANKRD20A3
ankyrin repeat domain 20 family, member A3
chr10_+_104404644 0.35 ENST00000462202.2
TRIM8
tripartite motif containing 8
chr2_-_158182105 0.35 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr14_+_22631122 0.34 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr7_-_23510086 0.34 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr12_-_117319236 0.34 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr8_-_116681123 0.34 ENST00000519674.1
TRPS1
trichorhinophalangeal syndrome I
chr14_+_32030582 0.34 ENST00000550649.1
ENST00000281081.7
NUBPL
nucleotide binding protein-like
chr13_+_103046954 0.34 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr12_-_24715307 0.33 ENST00000538905.1
RP11-444D3.1
RP11-444D3.1
chr10_-_95504 0.33 ENST00000447903.2
TUBB8
tubulin, beta 8 class VIII
chr13_-_99910673 0.32 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr4_-_48782259 0.32 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr5_-_142023766 0.32 ENST00000394496.2
FGF1
fibroblast growth factor 1 (acidic)
chr20_+_9049682 0.30 ENST00000334005.3
ENST00000378473.3
PLCB4
phospholipase C, beta 4
chr3_+_184056614 0.30 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr17_-_8702667 0.30 ENST00000329805.4
MFSD6L
major facilitator superfamily domain containing 6-like
chrX_-_46187069 0.29 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr12_-_95510743 0.29 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr6_+_16129308 0.28 ENST00000356840.3
ENST00000349606.4
MYLIP
myosin regulatory light chain interacting protein
chr9_-_124976154 0.27 ENST00000482062.1
LHX6
LIM homeobox 6
chr12_-_12491608 0.27 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr19_-_6057282 0.25 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr11_+_47291645 0.25 ENST00000395336.3
ENST00000402192.2
MADD
MAP-kinase activating death domain
chr11_-_71823266 0.24 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr19_-_40324767 0.24 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr12_-_67072714 0.24 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
GRIP1
glutamate receptor interacting protein 1
chr3_-_176914191 0.23 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_160147176 0.23 ENST00000470705.1
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr5_+_140079919 0.23 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr2_-_179914760 0.22 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr2_-_134326009 0.21 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr2_-_25194476 0.21 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr7_-_78400598 0.21 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_+_49644470 0.21 ENST00000508866.2
USP27X
ubiquitin specific peptidase 27, X-linked
chr6_+_78400375 0.21 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr20_-_34025999 0.19 ENST00000374369.3
GDF5
growth differentiation factor 5
chr10_+_122610687 0.19 ENST00000263461.6
WDR11
WD repeat domain 11
chr12_+_510742 0.19 ENST00000239830.4
CCDC77
coiled-coil domain containing 77
chr5_-_68665084 0.19 ENST00000509462.1
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr1_-_173020056 0.18 ENST00000239468.2
ENST00000404377.3
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr13_-_99910620 0.18 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr12_+_510795 0.17 ENST00000412006.2
CCDC77
coiled-coil domain containing 77
chr12_-_49449107 0.17 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr11_+_47291193 0.17 ENST00000428807.1
ENST00000402799.1
ENST00000406482.1
ENST00000349238.3
ENST00000311027.5
ENST00000407859.3
ENST00000395344.3
ENST00000444117.1
MADD
MAP-kinase activating death domain
chr14_-_75179774 0.17 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
AREL1
AC007956.1
apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chrX_+_10124977 0.17 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr7_-_78400364 0.17 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_140186647 0.17 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr1_-_115301235 0.17 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr1_-_170043709 0.16 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
KIFAP3
kinesin-associated protein 3
chr17_-_60142609 0.16 ENST00000397786.2
MED13
mediator complex subunit 13
chr1_+_161736072 0.15 ENST00000367942.3
ATF6
activating transcription factor 6
chr13_-_31038370 0.15 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr13_-_50018241 0.14 ENST00000409308.1
CAB39L
calcium binding protein 39-like
chr7_+_44646177 0.14 ENST00000443864.2
ENST00000447398.1
ENST00000449767.1
ENST00000419661.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr5_+_145583107 0.14 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr10_-_75385711 0.13 ENST00000433394.1
USP54
ubiquitin specific peptidase 54
chr11_-_13484713 0.13 ENST00000526841.1
ENST00000529708.1
ENST00000278174.5
ENST00000528120.1
BTBD10
BTB (POZ) domain containing 10
chr19_+_45394477 0.13 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr8_+_37553261 0.13 ENST00000331569.4
ZNF703
zinc finger protein 703
chr9_-_86593238 0.12 ENST00000351839.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr3_+_187461442 0.12 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chr7_+_44646162 0.12 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr20_-_48530230 0.11 ENST00000422556.1
SPATA2
spermatogenesis associated 2
chr6_+_33172407 0.11 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr12_-_122879969 0.10 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr3_+_185303962 0.10 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr13_-_50018140 0.10 ENST00000410043.1
ENST00000347776.5
CAB39L
calcium binding protein 39-like
chr1_+_10271674 0.09 ENST00000377086.1
KIF1B
kinesin family member 1B
chr19_-_37663332 0.09 ENST00000392157.2
ZNF585A
zinc finger protein 585A
chr6_-_137314371 0.09 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
RP11-55K22.5
chr15_+_67430339 0.09 ENST00000439724.3
SMAD3
SMAD family member 3
chr19_-_37663572 0.08 ENST00000588354.1
ENST00000292841.5
ENST00000355533.2
ENST00000356958.4
ZNF585A
zinc finger protein 585A
chr10_+_92631709 0.08 ENST00000413330.1
ENST00000277882.3
RPP30
ribonuclease P/MRP 30kDa subunit
chr3_-_127455200 0.08 ENST00000398101.3
MGLL
monoglyceride lipase
chr7_+_99717230 0.07 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr15_-_88799948 0.07 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr8_+_97773457 0.07 ENST00000521142.1
CPQ
carboxypeptidase Q
chr13_+_27825706 0.06 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21
ribosomal protein L21
chr2_+_108994466 0.05 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chrX_+_150565038 0.05 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr5_-_124082279 0.05 ENST00000513986.1
ZNF608
zinc finger protein 608
chr13_+_30002846 0.05 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr10_-_61900762 0.04 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_152118276 0.04 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr18_-_23671139 0.04 ENST00000579061.1
ENST00000542420.2
SS18
synovial sarcoma translocation, chromosome 18
chr5_+_145583156 0.04 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr12_+_96196875 0.03 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr19_+_46000479 0.03 ENST00000456399.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr5_-_68664989 0.03 ENST00000508954.1
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr5_-_68665296 0.02 ENST00000512152.1
ENST00000503245.1
ENST00000512561.1
ENST00000380822.4
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr6_+_42981922 0.02 ENST00000326974.4
ENST00000244670.8
KLHDC3
kelch domain containing 3
chr10_+_28822636 0.02 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chrX_-_70288234 0.02 ENST00000276105.3
ENST00000374274.3
SNX12
sorting nexin 12
chr13_+_30002741 0.02 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr5_-_68665469 0.02 ENST00000217893.5
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr11_-_110583912 0.01 ENST00000533353.1
ENST00000527598.1
ARHGAP20
Rho GTPase activating protein 20
chr7_-_99716940 0.01 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chrX_-_77150911 0.01 ENST00000373336.3
MAGT1
magnesium transporter 1
chr12_-_49418407 0.01 ENST00000526209.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr8_+_97773202 0.00 ENST00000519484.1
CPQ
carboxypeptidase Q
chr7_-_6010263 0.00 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr1_-_217250231 0.00 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of BRCA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.3 2.1 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.7 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.5 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.4 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.6 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.0 0.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.4 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 1.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.7 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.3 GO:0035766 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.7 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0033269 internode region of axon(GO:0033269)
0.1 0.7 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 1.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 1.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0015288 porin activity(GO:0015288)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha