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Illumina Body Map 2, young vs old

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Results for CAGUAGU

Z-value: 0.04

Motif logo

miRNA associated with seed CAGUAGU

NamemiRBASE accession
MIMAT0000232
MIMAT0004563
MIMAT0014992

Activity profile of CAGUAGU motif

Sorted Z-values of CAGUAGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_172756506 2.21 ENST00000265087.4
stanniocalcin 2
chr15_+_41221536 2.09 ENST00000249749.5
delta-like 4 (Drosophila)
chr6_-_75915757 2.06 ENST00000322507.8
collagen, type XII, alpha 1
chr3_+_61547585 1.98 ENST00000295874.10
ENST00000474889.1
protein tyrosine phosphatase, receptor type, G
chr7_-_19157248 1.96 ENST00000242261.5
twist family bHLH transcription factor 1
chr1_-_57045228 1.91 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr7_+_116139424 1.87 ENST00000222693.4
caveolin 2
chr9_+_2621798 1.75 ENST00000382100.3
very low density lipoprotein receptor
chr2_+_46524537 1.73 ENST00000263734.3
endothelial PAS domain protein 1
chr15_-_56209306 1.62 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr1_-_228135599 1.52 ENST00000272164.5
wingless-type MMTV integration site family, member 9A
chr2_+_36582857 1.49 ENST00000280527.2
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr1_+_162602244 1.49 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr11_+_101981169 1.46 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
Yes-associated protein 1
chr11_+_111473108 1.44 ENST00000304987.3
salt-inducible kinase 2
chr1_+_29563011 1.32 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
protein tyrosine phosphatase, receptor type, U
chr5_-_121413974 1.32 ENST00000231004.4
lysyl oxidase
chr4_+_55095264 1.31 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chrX_+_118108571 1.27 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr4_+_123747834 1.26 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr5_-_158526756 1.21 ENST00000313708.6
ENST00000517373.1
early B-cell factor 1
chr14_-_52535712 1.19 ENST00000216286.5
ENST00000541773.1
nidogen 2 (osteonidogen)
chr12_-_102874416 1.19 ENST00000392904.1
ENST00000337514.6
insulin-like growth factor 1 (somatomedin C)
chr12_-_16761007 1.18 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr3_-_24536253 1.17 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
thyroid hormone receptor, beta
chr1_+_61547894 1.11 ENST00000403491.3
nuclear factor I/A
chr3_-_98620500 1.11 ENST00000326840.6
discoidin, CUB and LCCL domain containing 2
chrX_-_8700171 1.10 ENST00000262648.3
Kallmann syndrome 1 sequence
chr6_-_139695757 1.10 ENST00000367651.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr4_-_129208940 1.08 ENST00000296425.5
progesterone receptor membrane component 2
chr11_+_12695944 1.02 ENST00000361905.4
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr12_-_80084862 1.01 ENST00000328827.4
PRKC, apoptosis, WT1, regulator
chr7_-_135433534 1.01 ENST00000338588.3
family with sequence similarity 180, member A
chr6_+_1312675 1.00 ENST00000296839.2
forkhead box Q1
chr11_+_832944 0.98 ENST00000322008.4
ENST00000397421.1
ENST00000529810.1
ENST00000526693.1
ENST00000525333.1
ENST00000524748.1
ENST00000527341.1
CD151 molecule (Raph blood group)
chr1_-_94079648 0.96 ENST00000370247.3
breast cancer anti-estrogen resistance 3
chr11_-_110583451 0.90 ENST00000260283.4
ENST00000528829.1
Rho GTPase activating protein 20
chr10_+_102106829 0.87 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr5_+_137801160 0.82 ENST00000239938.4
early growth response 1
chr10_+_74033672 0.82 ENST00000307365.3
DNA-damage-inducible transcript 4
chr13_-_76056250 0.82 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1 domain family, member 4
chr15_+_84322827 0.81 ENST00000286744.5
ENST00000567476.1
ADAMTS-like 3
chr10_+_5454505 0.79 ENST00000355029.4
neuroepithelial cell transforming 1
chr13_-_86373536 0.79 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr6_+_89790490 0.79 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr15_-_77363513 0.77 ENST00000267970.4
tetraspanin 3
chr11_+_120207787 0.77 ENST00000397843.2
ENST00000356641.3
Rho guanine nucleotide exchange factor (GEF) 12
chr14_-_35182994 0.76 ENST00000341223.3
cofilin 2 (muscle)
chr17_-_48546232 0.73 ENST00000258969.4
chondroadherin
chr7_-_27219632 0.72 ENST00000470747.4
Uncharacterized protein
chr4_-_73434498 0.71 ENST00000286657.4
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr10_-_13570533 0.67 ENST00000396900.2
ENST00000396898.2
BEN domain containing 7
chr1_+_165796753 0.66 ENST00000367879.4
uridine-cytidine kinase 2
chr10_+_72238517 0.64 ENST00000263563.6
phosphatase domain containing, paladin 1
chr12_+_19592602 0.63 ENST00000398864.3
ENST00000266508.9
AE binding protein 2
chr10_-_15762124 0.63 ENST00000378076.3
integrin, alpha 8
chr5_+_52083730 0.62 ENST00000282588.6
ENST00000274311.2
integrin, alpha 1
pelota homolog (Drosophila)
chr10_+_31608054 0.62 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
zinc finger E-box binding homeobox 1
chr15_-_49447835 0.62 ENST00000388901.5
ENST00000299259.6
COP9 signalosome subunit 2
chr12_-_77272765 0.60 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
cysteine and glycine-rich protein 2
chr11_-_44331679 0.59 ENST00000329255.3
ALX homeobox 4
chr2_-_216300784 0.58 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr2_+_159825143 0.58 ENST00000454300.1
ENST00000263635.6
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr11_+_33278811 0.57 ENST00000303296.4
ENST00000379016.3
homeodomain interacting protein kinase 3
chr7_-_129592700 0.55 ENST00000472396.1
ENST00000355621.3
ubiquitin-conjugating enzyme E2H
chr7_-_27205136 0.55 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr10_+_115803650 0.53 ENST00000369295.2
adrenoceptor beta 1
chr2_-_47168906 0.51 ENST00000444761.2
ENST00000409147.1
multiple coagulation factor deficiency 2
chr12_-_31479045 0.46 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr6_+_47445467 0.45 ENST00000359314.5
CD2-associated protein
chr3_+_110790590 0.45 ENST00000485303.1
poliovirus receptor-related 3
chr5_-_16936340 0.45 ENST00000507288.1
ENST00000513610.1
myosin X
chr2_+_148602058 0.45 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
activin A receptor, type IIA
chr4_-_74124502 0.43 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ankyrin repeat domain 17
chr12_-_120687948 0.43 ENST00000458477.2
paxillin
chr6_+_7107999 0.42 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr3_-_11762202 0.42 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
vestigial like 4 (Drosophila)
chr1_+_184356188 0.41 ENST00000235307.6
chromosome 1 open reading frame 21
chr19_+_41222998 0.41 ENST00000263370.2
inositol-trisphosphate 3-kinase C
chr5_-_148930960 0.38 ENST00000261798.5
ENST00000377843.2
casein kinase 1, alpha 1
chr12_-_56652111 0.38 ENST00000267116.7
ankyrin repeat domain 52
chrX_-_77150985 0.38 ENST00000358075.6
magnesium transporter 1
chr12_+_53774423 0.37 ENST00000426431.2
Sp1 transcription factor
chr5_-_179780312 0.37 ENST00000253778.8
glutamine-fructose-6-phosphate transaminase 2
chr15_-_37390482 0.37 ENST00000559085.1
ENST00000397624.3
Meis homeobox 2
chr21_-_36260980 0.36 ENST00000344691.4
ENST00000358356.5
runt-related transcription factor 1
chrX_+_16804544 0.36 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr8_-_42397037 0.36 ENST00000342228.3
solute carrier family 20 (phosphate transporter), member 2
chr15_+_41523335 0.34 ENST00000334660.5
calcineurin-like EF-hand protein 1
chr20_-_14318248 0.34 ENST00000378053.3
ENST00000341420.4
fibronectin leucine rich transmembrane protein 3
chr5_+_129240151 0.33 ENST00000305031.4
chondroitin sulfate synthase 3
chrX_+_119495934 0.33 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr3_+_152017181 0.33 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
muscleblind-like splicing regulator 1
chr5_-_77590480 0.33 ENST00000519295.1
ENST00000255194.6
adaptor-related protein complex 3, beta 1 subunit
chr6_+_35182176 0.32 ENST00000394681.1
ENST00000274938.7
signal peptide, CUB domain, EGF-like 3
chrX_+_76709648 0.30 ENST00000439435.1
fibroblast growth factor 16
chr9_-_107690420 0.30 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_-_158485387 0.30 ENST00000243349.8
activin A receptor, type IC
chr14_+_23067146 0.29 ENST00000428304.2
abhydrolase domain containing 4
chr2_-_204400113 0.28 ENST00000319170.5
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr10_+_112257596 0.28 ENST00000369583.3
dual specificity phosphatase 5
chr7_-_75988321 0.27 ENST00000307630.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr6_-_24721054 0.27 ENST00000378119.4
chromosome 6 open reading frame 62
chr15_+_49715293 0.26 ENST00000267843.4
ENST00000560270.1
fibroblast growth factor 7
chr13_+_58206655 0.25 ENST00000377918.3
protocadherin 17
chr11_+_129939779 0.25 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
amyloid beta (A4) precursor-like protein 2
chr6_+_53659746 0.24 ENST00000370888.1
leucine rich repeat containing 1
chr15_-_61521495 0.24 ENST00000335670.6
RAR-related orphan receptor A
chr8_-_66754172 0.23 ENST00000401827.3
phosphodiesterase 7A
chr7_+_128379346 0.23 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr1_+_15943995 0.21 ENST00000480945.1
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr3_+_38206975 0.21 ENST00000446845.1
ENST00000311806.3
oxidative stress responsive 1
chr6_+_10556215 0.21 ENST00000316170.3
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr1_+_2985760 0.21 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PR domain containing 16
chr2_+_85198216 0.21 ENST00000456682.1
ENST00000409785.4
potassium channel modulatory factor 1
chr19_+_1407517 0.20 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr5_+_75699040 0.19 ENST00000274364.6
IQ motif containing GTPase activating protein 2
chr1_-_177939041 0.19 ENST00000308284.6
SEC16 homolog B (S. cerevisiae)
chr14_-_27066636 0.18 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
neuro-oncological ventral antigen 1
chr17_+_36861735 0.18 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chrX_+_40944871 0.17 ENST00000378308.2
ENST00000324545.8
ubiquitin specific peptidase 9, X-linked
chr17_+_5185552 0.17 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
rabaptin, RAB GTPase binding effector protein 1
chr2_+_173292301 0.17 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
integrin, alpha 6
chr4_-_39979576 0.16 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr4_-_76957214 0.16 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr7_-_83824169 0.16 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_-_7382834 0.16 ENST00000380599.4
zinc finger and BTB domain containing 4
chr1_-_184723942 0.16 ENST00000318130.8
ER degradation enhancer, mannosidase alpha-like 3
chr13_+_48877895 0.15 ENST00000267163.4
retinoblastoma 1
chr3_-_105587879 0.15 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr1_-_93645818 0.15 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr16_+_81348528 0.15 ENST00000568107.2
gigaxonin
chr19_+_4969116 0.14 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
lysine (K)-specific demethylase 4B
chr2_+_138721850 0.14 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr8_+_37553261 0.14 ENST00000331569.4
zinc finger protein 703
chr1_-_29450399 0.14 ENST00000521452.1
transmembrane protein 200B
chrX_+_78003204 0.14 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr5_-_100238956 0.14 ENST00000231461.5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr16_+_58549378 0.13 ENST00000310682.2
ENST00000394266.4
ENST00000219315.4
SET domain containing 6
chr17_-_1303462 0.12 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr7_-_105752651 0.12 ENST00000470347.1
ENST00000455385.2
synaptophysin-like 1
chr3_+_122513642 0.11 ENST00000261038.5
disrupted in renal carcinoma 2
chr3_-_52931557 0.11 ENST00000504329.1
ENST00000355083.5
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr8_+_81397876 0.11 ENST00000430430.1
zinc finger and BTB domain containing 10
chr3_-_185655795 0.11 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
transformer 2 beta homolog (Drosophila)
chr4_-_76598296 0.11 ENST00000395719.3
GTPase activating protein (SH3 domain) binding protein 2
chr1_+_87170247 0.11 ENST00000370558.4
SH3-domain GRB2-like endophilin B1
chr15_+_83478370 0.11 ENST00000286760.4
WAS protein homolog associated with actin, golgi membranes and microtubules
chr4_+_148538517 0.10 ENST00000296582.3
ENST00000508208.1
transmembrane protein 184C
chr5_+_173315283 0.10 ENST00000265085.5
cytoplasmic polyadenylation element binding protein 4
chr10_+_20105157 0.10 ENST00000377242.3
ENST00000377252.4
plexin domain containing 2
chr1_-_46152174 0.10 ENST00000290795.3
ENST00000355105.3
GC-rich promoter binding protein 1-like 1
chr12_-_57030115 0.10 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
bromodomain adjacent to zinc finger domain, 2A
chrX_+_107683096 0.10 ENST00000328300.6
ENST00000361603.2
collagen, type IV, alpha 5
chr15_+_43425672 0.09 ENST00000260403.2
transmembrane protein 62
chr1_+_65613217 0.09 ENST00000545314.1
adenylate kinase 4
chr14_+_75745477 0.09 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FBJ murine osteosarcoma viral oncogene homolog
chr2_+_45878790 0.09 ENST00000306156.3
protein kinase C, epsilon
chr20_+_33814457 0.09 ENST00000246186.6
matrix metallopeptidase 24 (membrane-inserted)
chr7_-_95064264 0.08 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
paraoxonase 2
chr8_+_26149007 0.08 ENST00000380737.3
ENST00000524169.1
protein phosphatase 2, regulatory subunit B, alpha
chr3_-_167813672 0.08 ENST00000470487.1
golgi integral membrane protein 4
chr8_+_125551338 0.08 ENST00000276689.3
ENST00000518008.1
ENST00000522532.1
ENST00000517367.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr16_-_1464688 0.08 ENST00000389221.4
ENST00000508903.2
ENST00000397462.1
ENST00000301712.5
unkempt family zinc finger-like
chr2_+_42396472 0.08 ENST00000318522.5
ENST00000402711.2
echinoderm microtubule associated protein like 4
chr1_-_52344471 0.07 ENST00000352171.7
ENST00000354831.7
nardilysin (N-arginine dibasic convertase)
chr9_+_125703282 0.07 ENST00000373647.4
ENST00000402311.1
RAB GTPase activating protein 1
chr3_+_37284668 0.06 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
golgin A4
chr18_+_32073253 0.05 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
dystrobrevin, alpha
chr1_+_167190066 0.05 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU class 2 homeobox 1
chr2_-_164592497 0.05 ENST00000333129.3
ENST00000409634.1
fidgetin
chr14_-_64010046 0.05 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr3_+_180630090 0.04 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chrX_+_117861535 0.04 ENST00000371666.3
ENST00000371642.1
interleukin 13 receptor, alpha 1
chr20_+_35201857 0.04 ENST00000373874.2
TGFB-induced factor homeobox 2
chr9_+_33817461 0.03 ENST00000263228.3
ubiquitin-conjugating enzyme E2R 2
chr7_-_76829125 0.03 ENST00000248598.5
fibrinogen-like 2
chr1_-_19578003 0.03 ENST00000375199.3
ENST00000375208.3
ENST00000356068.2
ENST00000477853.1
ER membrane protein complex subunit 1
chr5_+_139493665 0.03 ENST00000331327.3
purine-rich element binding protein A
chr21_+_46494466 0.02 ENST00000539173.1
ENST00000389863.4
ENST00000348831.4
ENST00000437626.1
adenosine deaminase, RNA-specific, B1
chr14_+_103058948 0.02 ENST00000262241.6
REST corepressor 1
chr2_-_73053126 0.02 ENST00000272427.6
ENST00000410104.1
exocyst complex component 6B
chr5_+_149109825 0.02 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr8_+_67579807 0.02 ENST00000519289.1
ENST00000519561.1
ENST00000521889.1
C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr2_+_110371905 0.01 ENST00000356454.3
sosondowah ankyrin repeat domain family member C
chr1_-_235491462 0.01 ENST00000418304.1
ENST00000264183.3
ENST00000349213.3
AT rich interactive domain 4B (RBP1-like)
chr9_+_129567282 0.01 ENST00000449886.1
ENST00000373464.4
ENST00000450858.1
zinc finger and BTB domain containing 43
chr8_+_123793633 0.01 ENST00000314393.4
zinc fingers and homeoboxes 2
chr6_+_26365443 0.00 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr1_-_70820357 0.00 ENST00000370944.4
ENST00000262346.6
ankyrin repeat domain 13C
chr8_-_124286735 0.00 ENST00000395571.3
zinc fingers and homeoboxes 1
chr17_+_38219063 0.00 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
thyroid hormone receptor, alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of CAGUAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4 1.3 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.3 2.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.3 0.9 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 2.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 0.8 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.3 1.6 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.2 1.7 GO:0034436 glycoprotein transport(GO:0034436)
0.2 1.2 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 1.9 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 1.2 GO:0008050 female courtship behavior(GO:0008050)
0.2 1.1 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.2 0.6 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.2 1.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 1.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.5 GO:0003099 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.2 0.7 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 1.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 0.7 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 2.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.6 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.1 4.9 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.5 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 1.5 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 1.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:1990709 presynaptic active zone organization(GO:1990709)
0.1 0.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.4 GO:0060011 sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011)
0.1 0.4 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.3 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.2 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 1.1 GO:0072189 ureter development(GO:0072189)
0.0 0.8 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.8 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 1.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.0 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 1.2 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.4 GO:0006048 fructose 6-phosphate metabolic process(GO:0006002) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.1 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.9 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.4 2.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 0.6 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 0.6 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 1.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 1.7 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 1.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.0 GO:0005604 basement membrane(GO:0005604)
0.0 5.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.4 1.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 1.3 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.2 1.7 GO:0050815 phosphoserine binding(GO:0050815)
0.2 2.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 0.5 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.2 0.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0038100 nodal binding(GO:0038100)
0.1 0.9 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 3.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.1 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.1 GO:0005112 Notch binding(GO:0005112)
0.1 2.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0098821 inhibin binding(GO:0034711) BMP receptor activity(GO:0098821)
0.0 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 2.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 1.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 5.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 5.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 3.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 2.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors