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Illumina Body Map 2, young vs old

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Results for CAGUGCA

Z-value: 0.87

Motif logo

miRNA associated with seed CAGUGCA

NamemiRBASE accession
MIMAT0000243
MIMAT0000759
MIMAT0000438

Activity profile of CAGUGCA motif

Sorted Z-values of CAGUGCA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_141645645 1.93 ENST00000519980.1
ENST00000220592.5
argonaute RISC catalytic component 2
chr19_-_40324255 1.88 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr5_+_7396141 1.88 ENST00000338316.4
adenylate cyclase 2 (brain)
chr16_+_11762270 1.88 ENST00000329565.5
stannin
chr1_+_145438469 1.82 ENST00000369317.4
thioredoxin interacting protein
chr5_-_59189545 1.76 ENST00000340635.6
phosphodiesterase 4D, cAMP-specific
chr6_+_17281573 1.74 ENST00000379052.5
RNA binding motif protein 24
chr21_-_28338732 1.67 ENST00000284987.5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr12_-_26278030 1.63 ENST00000242728.4
basic helix-loop-helix family, member e41
chr11_+_113930291 1.55 ENST00000335953.4
zinc finger and BTB domain containing 16
chr1_+_101702417 1.47 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr6_+_144471643 1.37 ENST00000367568.4
syntaxin 11
chr3_+_69812877 1.36 ENST00000457080.1
ENST00000328528.6
microphthalmia-associated transcription factor
chr2_+_121103706 1.34 ENST00000295228.3
inhibin, beta B
chr5_+_102594403 1.29 ENST00000319933.2
chromosome 5 open reading frame 30
chr8_-_66754172 1.24 ENST00000401827.3
phosphodiesterase 7A
chr3_+_180630090 1.24 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr6_-_91006461 1.23 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr12_-_76478686 1.17 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr18_+_59000815 1.16 ENST00000262717.4
cadherin 20, type 2
chr20_+_57267669 1.12 ENST00000356091.6
aminopeptidase-like 1
chr5_-_172198190 1.11 ENST00000239223.3
dual specificity phosphatase 1
chr7_-_139876812 1.09 ENST00000397560.2
lysine (K)-specific demethylase 7A
chr3_-_71774516 1.08 ENST00000425534.3
eukaryotic translation initiation factor 4E family member 3
chr2_+_70142189 1.06 ENST00000264444.2
MAX dimerization protein 1
chr3_-_160283348 1.06 ENST00000334256.4
karyopherin alpha 4 (importin alpha 3)
chr12_+_54402790 1.04 ENST00000040584.4
homeobox C8
chr10_+_60094735 1.02 ENST00000373910.4
ubiquitin-conjugating enzyme E2D 1
chr7_-_15726296 1.02 ENST00000262041.5
mesenchyme homeobox 2
chr3_-_125313934 1.01 ENST00000296220.5
oxysterol binding protein-like 11
chr2_+_28974668 1.00 ENST00000296122.6
ENST00000395366.2
protein phosphatase 1, catalytic subunit, beta isozyme
chr19_+_13135386 0.96 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_-_1532106 0.91 ENST00000301335.5
ENST00000382147.4
solute carrier family 43 (amino acid system L transporter), member 2
chr4_-_42659102 0.88 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr1_+_12227035 0.88 ENST00000376259.3
ENST00000536782.1
tumor necrosis factor receptor superfamily, member 1B
chr11_+_109964087 0.87 ENST00000278590.3
zinc finger CCCH-type containing 12C
chr19_+_7598890 0.86 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
patatin-like phospholipase domain containing 6
chr10_+_47894023 0.85 ENST00000358474.5
family with sequence similarity 21, member B
chr8_+_145159376 0.85 ENST00000322428.5
MAF1 homolog (S. cerevisiae)
chr18_+_43753974 0.85 ENST00000282059.6
ENST00000321319.6
chromosome 18 open reading frame 25
chr17_-_66287257 0.84 ENST00000327268.4
solute carrier family 16, member 6
chr20_-_48330377 0.81 ENST00000371711.4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr2_+_56411131 0.80 ENST00000407595.2
coiled-coil domain containing 85A
chrX_-_74376108 0.79 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr3_-_122233723 0.79 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
karyopherin alpha 1 (importin alpha 5)
chr3_+_138066539 0.78 ENST00000289104.4
muscle RAS oncogene homolog
chr5_-_78809950 0.76 ENST00000334082.6
homer homolog 1 (Drosophila)
chr3_+_9691117 0.76 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
myotubularin related protein 14
chr1_+_78470530 0.76 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_+_97736197 0.76 ENST00000297293.5
lemur tyrosine kinase 2
chr17_-_79885576 0.75 ENST00000574686.1
ENST00000357736.4
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr5_+_96271141 0.75 ENST00000231368.5
leucyl/cystinyl aminopeptidase
chr17_+_80477571 0.75 ENST00000335255.5
forkhead box K2
chr8_+_61591337 0.74 ENST00000423902.2
chromodomain helicase DNA binding protein 7
chr5_-_90679145 0.74 ENST00000265138.3
arrestin domain containing 3
chr17_-_7232585 0.73 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
neuralized E3 ubiquitin protein ligase 4
chr4_+_6784401 0.72 ENST00000425103.1
ENST00000307659.5
KIAA0232
chr12_-_8088871 0.71 ENST00000075120.7
solute carrier family 2 (facilitated glucose transporter), member 3
chr5_+_95997918 0.71 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
calpastatin
chr9_-_110251836 0.68 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr1_-_51984908 0.67 ENST00000371730.2
epidermal growth factor receptor pathway substrate 15
chr2_-_39348137 0.67 ENST00000426016.1
son of sevenless homolog 1 (Drosophila)
chr1_+_244214577 0.67 ENST00000358704.4
zinc finger and BTB domain containing 18
chr17_+_54671047 0.67 ENST00000332822.4
noggin
chr13_+_98605902 0.66 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
importin 5
chr7_-_95225768 0.65 ENST00000005178.5
pyruvate dehydrogenase kinase, isozyme 4
chr1_+_36273743 0.64 ENST00000373210.3
argonaute RISC catalytic component 4
chr1_+_66797687 0.64 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chr2_-_24583168 0.64 ENST00000361999.3
intersectin 2
chr10_+_24755416 0.63 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr13_+_73632897 0.63 ENST00000377687.4
Kruppel-like factor 5 (intestinal)
chrX_+_118108571 0.63 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr7_-_6312206 0.62 ENST00000350796.3
cytohesin 3
chr15_-_52861394 0.62 ENST00000563277.1
ENST00000566423.1
cAMP-regulated phosphoprotein, 19kDa
chr6_+_64345698 0.62 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHD finger protein 3
chr7_-_86688990 0.62 ENST00000450689.2
KIAA1324-like
chr14_-_61190754 0.61 ENST00000216513.4
SIX homeobox 4
chr11_-_46940074 0.61 ENST00000378623.1
ENST00000534404.1
low density lipoprotein receptor-related protein 4
chr17_+_46125707 0.61 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
nuclear factor, erythroid 2-like 1
chr1_-_173991434 0.61 ENST00000367696.2
ring finger and CCCH-type domains 1
chr12_-_56694142 0.58 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chr1_-_153895377 0.58 ENST00000368655.4
GATA zinc finger domain containing 2B
chr2_+_241508039 0.58 ENST00000270357.4
arginyl aminopeptidase (aminopeptidase B)-like 1
chr1_-_10856694 0.57 ENST00000377022.3
ENST00000344008.5
castor zinc finger 1
chr2_+_228336849 0.57 ENST00000409979.2
ENST00000310078.8
ArfGAP with FG repeats 1
chr20_+_13202418 0.56 ENST00000262487.4
isthmin 1, angiogenesis inhibitor
chr15_-_41408409 0.56 ENST00000361937.3
INO80 complex subunit
chr7_+_138916231 0.55 ENST00000473989.3
ENST00000288561.8
ubinuclein 2
chr19_+_926000 0.55 ENST00000263620.3
AT rich interactive domain 3A (BRIGHT-like)
chr2_-_105946491 0.55 ENST00000393359.2
transforming growth factor, beta receptor associated protein 1
chr3_+_47324424 0.53 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
kelch-like family member 18
chr3_-_197476560 0.53 ENST00000273582.5
KIAA0226
chr12_+_68042495 0.52 ENST00000344096.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr3_-_53381539 0.52 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
decapping mRNA 1A
chr1_-_46598284 0.51 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr11_+_33278811 0.51 ENST00000303296.4
ENST00000379016.3
homeodomain interacting protein kinase 3
chr9_-_36400213 0.51 ENST00000259605.6
ENST00000353739.4
ring finger protein 38
chr1_-_27930102 0.51 ENST00000247087.5
ENST00000374011.2
AT hook, DNA binding motif, containing 1
chr16_-_85045131 0.49 ENST00000313732.4
zinc finger, DHHC-type containing 7
chr19_-_4066890 0.49 ENST00000322357.4
zinc finger and BTB domain containing 7A
chr1_-_217262969 0.48 ENST00000361525.3
estrogen-related receptor gamma
chr20_-_5591626 0.48 ENST00000379019.4
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr1_-_205180664 0.48 ENST00000367161.3
ENST00000367162.3
ENST00000367160.4
dual serine/threonine and tyrosine protein kinase
chr21_-_44846999 0.48 ENST00000270162.6
salt-inducible kinase 1
chr14_-_35182994 0.48 ENST00000341223.3
cofilin 2 (muscle)
chr14_-_93582148 0.48 ENST00000267615.6
ENST00000553452.1
inositol-tetrakisphosphate 1-kinase
chr2_-_36825281 0.48 ENST00000405912.3
ENST00000379245.4
fasciculation and elongation protein zeta 2 (zygin II)
chr16_-_30107491 0.47 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
yippee-like 3 (Drosophila)
chr9_+_137218362 0.47 ENST00000481739.1
retinoid X receptor, alpha
chr16_-_73082274 0.47 ENST00000268489.5
zinc finger homeobox 3
chr1_-_154842741 0.47 ENST00000271915.4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr11_+_59522532 0.47 ENST00000337979.4
ENST00000535361.1
syntaxin 3
chr1_-_38325256 0.47 ENST00000373036.4
metal-regulatory transcription factor 1
chr11_-_1593150 0.47 ENST00000397374.3
dual specificity phosphatase 8
chr8_-_22550815 0.46 ENST00000317216.2
early growth response 3
chr18_-_12657988 0.46 ENST00000410092.3
ENST00000409402.4
spire-type actin nucleation factor 1
chr1_+_41249539 0.45 ENST00000347132.5
ENST00000509682.2
potassium voltage-gated channel, KQT-like subfamily, member 4
chr4_+_142557717 0.45 ENST00000320650.4
ENST00000296545.7
interleukin 15
chr4_-_120550146 0.45 ENST00000354960.3
phosphodiesterase 5A, cGMP-specific
chr16_-_77468945 0.44 ENST00000282849.5
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr11_+_818902 0.44 ENST00000336615.4
patatin-like phospholipase domain containing 2
chr1_-_214724566 0.44 ENST00000366956.5
protein tyrosine phosphatase, non-receptor type 14
chr17_+_55333876 0.44 ENST00000284073.2
musashi RNA-binding protein 2
chr5_-_39074479 0.44 ENST00000514735.1
ENST00000296782.5
ENST00000357387.3
RPTOR independent companion of MTOR, complex 2
chr15_-_61521495 0.43 ENST00000335670.6
RAR-related orphan receptor A
chr1_-_109584608 0.43 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WD repeat domain 47
chr12_-_54813229 0.43 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr13_+_28813645 0.42 ENST00000282391.5
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr8_-_116681221 0.42 ENST00000395715.3
trichorhinophalangeal syndrome I
chr11_-_10315741 0.42 ENST00000256190.8
SET binding factor 2
chr17_-_58469474 0.42 ENST00000300896.4
ubiquitin specific peptidase 32
chr19_-_55770311 0.41 ENST00000412770.2
protein phosphatase 6, regulatory subunit 1
chr12_-_50101165 0.41 ENST00000352151.5
ENST00000335154.5
ENST00000293590.5
formin-like 3
chr9_+_128024067 0.40 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GTPase activating protein and VPS9 domains 1
chr1_-_154928562 0.40 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chrX_+_109246285 0.40 ENST00000372073.1
ENST00000372068.2
ENST00000288381.4
transmembrane protein 164
chr14_-_50698276 0.39 ENST00000216373.5
son of sevenless homolog 2 (Drosophila)
chr10_-_3827417 0.39 ENST00000497571.1
ENST00000542957.1
Kruppel-like factor 6
chr3_-_53080047 0.39 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chr5_-_98262240 0.39 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr18_+_60190226 0.39 ENST00000269499.5
zinc finger, CCHC domain containing 2
chr5_+_125935960 0.39 ENST00000297540.4
phosphorylated adaptor for RNA export
chr6_+_143929307 0.38 ENST00000427704.2
ENST00000305766.6
phosphatase and actin regulator 2
chr14_-_55878538 0.38 ENST00000247178.5
autophagy related 14
chr11_-_59436453 0.38 ENST00000300146.9
protein associated with topoisomerase II homolog 1 (yeast)
chr22_+_18121562 0.38 ENST00000355028.3
BCL2-like 13 (apoptosis facilitator)
chr7_+_77325738 0.38 ENST00000334955.8
round spermatid basic protein 1-like
chr18_-_45456930 0.37 ENST00000262160.6
ENST00000587269.1
SMAD family member 2
chr5_+_173315283 0.37 ENST00000265085.5
cytoplasmic polyadenylation element binding protein 4
chr7_+_56119323 0.37 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
chaperonin containing TCP1, subunit 6A (zeta 1)
chr10_+_102295616 0.37 ENST00000299163.6
hypoxia inducible factor 1, alpha subunit inhibitor
chr17_+_5031687 0.37 ENST00000250066.6
ENST00000304328.5
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr6_-_88876058 0.36 ENST00000369501.2
cannabinoid receptor 1 (brain)
chr18_-_53255766 0.36 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr8_+_144679984 0.36 ENST00000504548.2
ENST00000321385.3
tigger transposable element derived 5
chr12_-_8025442 0.36 ENST00000340749.5
ENST00000535295.1
ENST00000539234.1
solute carrier family 2 (facilitated glucose transporter), member 14
chr11_+_61717842 0.36 ENST00000449131.2
bestrophin 1
chr15_+_51200859 0.36 ENST00000261842.5
adaptor-related protein complex 4, epsilon 1 subunit
chr15_+_41221536 0.35 ENST00000249749.5
delta-like 4 (Drosophila)
chr6_+_15246501 0.35 ENST00000341776.2
jumonji, AT rich interactive domain 2
chr3_-_100120223 0.34 ENST00000284320.5
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr19_+_8483272 0.34 ENST00000602117.1
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr7_-_107204337 0.34 ENST00000605888.1
ENST00000347053.3
component of oligomeric golgi complex 5
chr2_+_86947296 0.33 ENST00000283632.4
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_-_30585009 0.33 ENST00000376511.2
protein phosphatase 1, regulatory subunit 10
chr10_+_89622870 0.33 ENST00000371953.3
phosphatase and tensin homolog
chr17_-_53499310 0.33 ENST00000262065.3
monocyte to macrophage differentiation-associated
chr6_+_161412759 0.33 ENST00000366919.2
ENST00000392142.4
ENST00000366920.2
ENST00000348824.7
mitogen-activated protein kinase kinase kinase 4
chr1_-_229694406 0.32 ENST00000344517.4
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr9_-_26947453 0.32 ENST00000397292.3
phospholipase A2-activating protein
chr2_-_9695847 0.32 ENST00000310823.3
ENST00000497134.1
ADAM metallopeptidase domain 17
chr1_+_112938803 0.31 ENST00000271277.6
CTTNBP2 N-terminal like
chr12_+_110719032 0.31 ENST00000395494.2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr3_+_9773409 0.31 ENST00000433861.2
ENST00000424362.1
ENST00000383829.2
ENST00000302054.3
ENST00000420291.1
bromodomain and PHD finger containing, 1
chr6_+_163835669 0.30 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI, KH domain containing, RNA binding
chrX_+_77166172 0.30 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr6_+_147525541 0.30 ENST00000367481.3
ENST00000546097.1
syntaxin binding protein 5 (tomosyn)
chr19_+_10654561 0.30 ENST00000309469.4
autophagy related 4D, cysteine peptidase
chr3_+_5163905 0.30 ENST00000256496.3
ENST00000419534.2
ADP-ribosylation factor-like 8B
chr6_-_16761678 0.30 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr21_-_47706205 0.29 ENST00000397708.1
minichromosome maintenance complex component 3 associated protein
chrX_+_149861836 0.29 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
myotubularin related protein 1
chr1_-_67896095 0.29 ENST00000370994.4
SERPINE1 mRNA binding protein 1
chr2_+_26256938 0.29 ENST00000264710.4
RAB10, member RAS oncogene family
chr6_+_44094627 0.28 ENST00000259746.9
transmembrane protein 63B
chr1_+_218519577 0.28 ENST00000366930.4
ENST00000366929.4
transforming growth factor, beta 2
chr10_-_50603497 0.28 ENST00000374139.2
dorsal root ganglia homeobox
chr18_+_8609402 0.28 ENST00000329286.6
RAB12, member RAS oncogene family
chr12_-_57030115 0.28 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
bromodomain adjacent to zinc finger domain, 2A
chr22_+_40573921 0.27 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr20_+_34359905 0.27 ENST00000374012.3
ENST00000439301.1
ENST00000339089.6
ENST00000374000.4
PHD finger protein 20
chr2_-_55237484 0.27 ENST00000394609.2
reticulon 4
chr14_-_68283291 0.27 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr16_-_69419871 0.27 ENST00000603068.1
ENST00000254942.3
ENST00000567296.2
telomeric repeat binding factor 2
chr2_-_180129484 0.27 ENST00000428443.3
SEC14 and spectrin domains 1
chr17_+_30813576 0.27 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr1_-_52344471 0.27 ENST00000352171.7
ENST00000354831.7
nardilysin (N-arginine dibasic convertase)
chr20_+_43514315 0.27 ENST00000353703.4
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr6_+_107811162 0.27 ENST00000317357.5
sine oculis binding protein homolog (Drosophila)
chr3_+_43328004 0.26 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNF related kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of CAGUGCA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4 1.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 2.9 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.4 1.7 GO:0044691 tooth eruption(GO:0044691)
0.2 0.7 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.5 GO:0070372 ERK1 and ERK2 cascade(GO:0070371) regulation of ERK1 and ERK2 cascade(GO:0070372)
0.2 1.6 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.2 0.9 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 0.6 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 0.8 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.1 GO:0001757 somite specification(GO:0001757)
0.2 1.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.7 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.2 0.8 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 0.5 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.2 0.6 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.4 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.8 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.7 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.7 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.3 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.4 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 1.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.3 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.3 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.6 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.4 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 1.8 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 1.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 1.0 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.4 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 1.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.2 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.3 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538)
0.1 1.3 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 0.3 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 3.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.6 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.8 GO:0002347 response to tumor cell(GO:0002347)
0.1 1.0 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.5 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.8 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0032489 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 1.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0070662 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.4 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.4 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.3 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 2.0 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 1.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.8 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.3 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.0 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.7 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.3 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 1.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.1 GO:0042587 glycogen granule(GO:0042587)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.5 GO:0033263 CORVET complex(GO:0033263)
0.1 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.8 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 2.0 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 3.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0098808 mRNA cap binding(GO:0098808)
0.4 1.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 0.8 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.2 1.0 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.2 0.6 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 1.6 GO:0043426 MRF binding(GO:0043426)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.8 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.5 GO:0052831 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 2.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 1.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.3 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 1.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.3 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 3.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.7 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 2.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 1.2 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling