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Illumina Body Map 2, young vs old

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Results for CDC5L

Z-value: 0.26

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Transcription factors associated with CDC5L

Gene Symbol Gene ID Gene Info
ENSG00000096401.7 cell division cycle 5 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDC5Lhg19_v2_chr6_+_44355257_443553150.291.1e-01Click!

Activity profile of CDC5L motif

Sorted Z-values of CDC5L motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_616711 8.34 ENST00000579494.1
clusterin-like 1 (retinal)
chr18_+_616672 7.97 ENST00000338387.7
clusterin-like 1 (retinal)
chr10_-_69597915 6.20 ENST00000225171.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_+_178276488 5.81 ENST00000432997.1
ENST00000455865.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr10_-_69597810 5.79 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr7_-_16921601 5.11 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
anterior gradient 3
chr8_-_124749609 5.06 ENST00000262219.6
ENST00000419625.1
annexin A13
chr9_-_28670283 4.79 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr10_-_69597828 4.13 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr16_+_80574854 3.67 ENST00000305904.6
ENST00000568035.1
dynein, light chain, roadblock-type 2
chr18_-_25616519 3.55 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chrX_+_36246735 3.52 ENST00000378653.3
chromosome X open reading frame 30
chr1_+_43613612 3.22 ENST00000335282.4
family with sequence similarity 183, member A
chr6_-_165723088 3.18 ENST00000230301.8
chromosome 6 open reading frame 118
chr5_-_35938674 3.15 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
calcyphosine-like
chr3_-_155394099 3.03 ENST00000414191.1
phospholipase C, eta 1
chr5_+_94727048 2.88 ENST00000283357.5
family with sequence similarity 81, member B
chr2_+_166095898 2.85 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr15_+_81391740 2.81 ENST00000561216.1
chromosome 15 open reading frame 26
chr18_-_24445729 2.77 ENST00000383168.4
aquaporin 4
chr11_-_13517565 2.68 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr8_+_24772455 2.63 ENST00000433454.2
neurofilament, medium polypeptide
chr17_+_45908974 2.62 ENST00000269025.4
leucine rich repeat containing 46
chr11_-_31014214 2.58 ENST00000406071.2
ENST00000339794.5
doublecortin domain containing 1
chr11_-_83984231 2.50 ENST00000330014.6
ENST00000537455.1
ENST00000376106.3
ENST00000418306.2
ENST00000531015.1
discs, large homolog 2 (Drosophila)
chr10_-_61495760 2.49 ENST00000395347.1
solute carrier family 16, member 9
chr19_-_10697895 2.46 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr16_+_4845379 2.39 ENST00000588606.1
ENST00000586005.1
small integral membrane protein 22
chr15_+_54901540 2.34 ENST00000539562.2
unc-13 homolog C (C. elegans)
chr4_-_168155577 2.34 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_204135450 2.31 ENST00000272190.8
ENST00000367195.2
renin
chrX_+_36254051 2.25 ENST00000378657.4
chromosome X open reading frame 30
chrX_+_103031758 2.24 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr3_+_35721106 2.23 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr15_+_32933866 2.20 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
secretogranin V (7B2 protein)
chr8_-_133637624 2.16 ENST00000522789.1
leucine rich repeat containing 6
chr9_-_93405352 2.15 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chr12_-_87232644 2.12 ENST00000549405.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_-_136847099 2.10 ENST00000438100.2
microtubule-associated protein 7
chr12_+_79439405 2.08 ENST00000552744.1
synaptotagmin I
chr8_+_35649365 2.06 ENST00000437887.1
Uncharacterized protein
chr3_-_155394152 2.06 ENST00000494598.1
phospholipase C, eta 1
chr6_+_80129989 2.05 ENST00000429444.1
RP1-232L24.3
chr6_-_136847610 2.04 ENST00000454590.1
ENST00000432797.2
microtubule-associated protein 7
chr1_+_38022572 2.04 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr3_+_35721182 2.04 ENST00000413378.1
ENST00000417925.1
cAMP-regulated phosphoprotein, 21kDa
chr12_-_21487829 2.03 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
solute carrier organic anion transporter family, member 1A2
chr1_-_154178803 2.00 ENST00000368525.3
chromosome 1 open reading frame 189
chr6_-_49681235 1.99 ENST00000339139.4
cysteine-rich secretory protein 2
chr1_+_15668240 1.97 ENST00000444385.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr3_+_63428982 1.93 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
synaptoporin
chr1_+_38022513 1.92 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr18_-_31628558 1.83 ENST00000535384.1
nucleolar protein 4
chr15_+_54305101 1.83 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr3_-_120365866 1.78 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr8_+_76452097 1.77 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr13_+_78315295 1.75 ENST00000351546.3
SLAIN motif family, member 1
chr13_+_78315348 1.74 ENST00000441784.1
SLAIN motif family, member 1
chrX_+_35937843 1.71 ENST00000297866.5
chromosome X open reading frame 22
chr3_+_107096188 1.71 ENST00000261058.1
coiled-coil domain containing 54
chr6_+_76599809 1.70 ENST00000430435.1
myosin VI
chr15_-_94614049 1.69 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
chr12_-_371994 1.68 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
solute carrier family 6 (neurotransmitter transporter), member 13
chr18_-_40857493 1.68 ENST00000255224.3
synaptotagmin IV
chr3_+_108321623 1.61 ENST00000497905.1
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr5_-_61031495 1.61 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
chr5_+_173473662 1.61 ENST00000519717.1
Neuron-specific protein family member 2
chr6_+_127898312 1.61 ENST00000329722.7
chromosome 6 open reading frame 58
chr7_-_14880892 1.61 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
diacylglycerol kinase, beta 90kDa
chr12_-_45307711 1.60 ENST00000333837.4
ENST00000551949.1
NEL-like 2 (chicken)
chr1_+_197237352 1.57 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chr17_-_7493390 1.56 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SRY (sex determining region Y)-box 15
chrX_+_107020963 1.56 ENST00000509000.2
nuclear cap binding protein subunit 2-like
chr2_-_100925967 1.55 ENST00000409647.1
LON peptidase N-terminal domain and ring finger 2
chr10_-_98118724 1.55 ENST00000393870.2
oligodendrocytic myelin paranodal and inner loop protein
chr18_+_50278430 1.54 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
deleted in colorectal carcinoma
chr10_-_81742364 1.54 ENST00000444384.3
surfactant protein D
chr14_+_62462541 1.53 ENST00000430451.2
synaptotagmin XVI
chr3_+_35721130 1.52 ENST00000432450.1
cAMP-regulated phosphoprotein, 21kDa
chr10_-_23528745 1.52 ENST00000376501.5
chromosome 10 open reading frame 115
chr12_+_79439461 1.51 ENST00000552624.1
synaptotagmin I
chr19_+_16830815 1.50 ENST00000549814.1
NACHT and WD repeat domain containing 1
chr12_-_39734783 1.49 ENST00000552961.1
kinesin family member 21A
chr17_-_57604200 1.48 ENST00000577478.1
RP11-567L7.6
chr18_-_24765248 1.48 ENST00000580774.1
ENST00000284224.8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr10_+_115511213 1.44 ENST00000361048.1
pleckstrin homology domain containing, family S member 1
chr21_+_34442439 1.44 ENST00000382348.1
ENST00000333063.5
oligodendrocyte transcription factor 1
chr15_+_81299370 1.44 ENST00000560091.1
chromosome 15 open reading frame 26
chrX_+_36065053 1.43 ENST00000313548.4
calponin homology domain containing 2
chr7_-_122339162 1.43 ENST00000340112.2
ring finger protein 133
chr5_+_147648393 1.43 ENST00000511106.1
ENST00000398450.4
serine peptidase inhibitor, Kazal type 13 (putative)
chr10_+_115511434 1.42 ENST00000369312.4
pleckstrin homology domain containing, family S member 1
chr3_-_116163830 1.42 ENST00000333617.4
limbic system-associated membrane protein
chr9_-_19786926 1.42 ENST00000341998.2
ENST00000286344.3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr2_+_210444748 1.42 ENST00000392194.1
microtubule-associated protein 2
chr1_-_86043921 1.41 ENST00000535924.2
dimethylarginine dimethylaminohydrolase 1
chr2_+_210517895 1.41 ENST00000447185.1
microtubule-associated protein 2
chr3_+_63428752 1.38 ENST00000295894.5
synaptoporin
chr11_-_102651343 1.37 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr10_+_46994087 1.37 ENST00000374317.1
G protein regulated inducer of neurite outgrowth 2
chr2_-_100939195 1.37 ENST00000393437.3
LON peptidase N-terminal domain and ring finger 2
chr9_-_21368075 1.36 ENST00000449498.1
interferon, alpha 13
chr18_-_10701979 1.35 ENST00000538948.1
ENST00000285141.4
piezo-type mechanosensitive ion channel component 2
chr2_-_175712479 1.34 ENST00000443238.1
chimerin 1
chr17_+_48911942 1.34 ENST00000426127.1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr7_+_29519486 1.31 ENST00000409041.4
chimerin 2
chr2_-_44550441 1.31 ENST00000420756.1
ENST00000444696.1
prolyl endopeptidase-like
chr2_+_200472779 1.31 ENST00000427045.1
ENST00000419243.1
AC093590.1
chr5_+_161495038 1.28 ENST00000393933.4
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr16_+_33204156 1.28 ENST00000398667.4
TP53 target 3C
chr13_+_78315528 1.27 ENST00000496045.1
SLAIN motif family, member 1
chr6_-_49712072 1.26 ENST00000423399.2
cysteine-rich secretory protein 3
chr18_-_31603603 1.26 ENST00000586553.1
nucleolar protein 4
chr16_-_5116025 1.26 ENST00000472572.3
ENST00000315997.5
ENST00000422873.1
ENST00000350219.4
chromosome 16 open reading frame 89
chr13_-_86373536 1.25 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr17_+_61151306 1.24 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr12_+_81664424 1.23 ENST00000549161.1
ENST00000550138.1
RP11-121G22.3
chr1_+_10509971 1.23 ENST00000320498.4
cortistatin
chrX_-_142605301 1.21 ENST00000370503.2
SPANX family, member N3
chr12_+_8309630 1.20 ENST00000396570.3
zinc finger protein 705A
chr1_+_50513686 1.20 ENST00000448907.2
ELAV like neuron-specific RNA binding protein 4
chr1_+_110254850 1.18 ENST00000369812.5
ENST00000256593.3
ENST00000369813.1
glutathione S-transferase mu 5
chr8_+_104892639 1.18 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr17_+_56315787 1.17 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr14_-_80678512 1.17 ENST00000553968.1
deiodinase, iodothyronine, type II
chr8_-_57233103 1.17 ENST00000303749.3
ENST00000522671.1
short chain dehydrogenase/reductase family 16C, member 5
chr2_-_2334888 1.17 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr5_+_140227048 1.17 ENST00000532602.1
protocadherin alpha 9
chr5_-_82969405 1.16 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr10_+_51549498 1.16 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr18_-_31802282 1.16 ENST00000535475.1
nucleolar protein 4
chr5_+_140174429 1.16 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
protocadherin alpha 2
chr13_+_78315466 1.16 ENST00000314070.5
ENST00000462234.1
SLAIN motif family, member 1
chr13_+_76334498 1.15 ENST00000534657.1
LIM domain 7
chr10_-_69425399 1.15 ENST00000330298.6
catenin (cadherin-associated protein), alpha 3
chr12_-_120189900 1.13 ENST00000546026.1
citron (rho-interacting, serine/threonine kinase 21)
chr2_-_241080069 1.12 ENST00000319460.1
otospiralin
chr10_-_104597286 1.12 ENST00000369887.3
cytochrome P450, family 17, subfamily A, polypeptide 1
chr7_+_5465382 1.12 ENST00000609130.1
RP11-1275H24.2
chr1_+_50571949 1.11 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr1_+_156308403 1.10 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSSK6 activating co-chaperone
chr6_-_137365402 1.10 ENST00000541547.1
interleukin 20 receptor, alpha
chr1_+_166958346 1.09 ENST00000367872.4
maelstrom spermatogenic transposon silencer
chr19_+_58545369 1.09 ENST00000391700.1
zinc finger and SCAN domain containing 1
chr4_-_87028478 1.08 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr3_-_112013071 1.08 ENST00000487372.1
ENST00000486574.1
ENST00000305815.5
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
chr3_+_107364683 1.07 ENST00000413213.1
bobby sox homolog (Drosophila)
chr10_-_62493223 1.07 ENST00000373827.2
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_132891461 1.06 ENST00000275198.1
trace amine associated receptor 6
chr3_-_108672609 1.06 ENST00000393963.3
ENST00000471108.1
guanylate cyclase activator 1C
chr5_+_140514782 1.06 ENST00000231134.5
protocadherin beta 5
chr6_-_88001706 1.06 ENST00000369576.2
gap junction protein, beta 7, 25kDa
chr8_-_79470728 1.06 ENST00000522807.1
ENST00000519242.1
ENST00000522302.1
RP11-594N15.2
chrX_-_15683147 1.02 ENST00000380342.3
transmembrane protein 27
chr19_+_58545434 1.02 ENST00000282326.1
ENST00000601162.1
zinc finger and SCAN domain containing 1
chr3_-_178865747 1.02 ENST00000435560.1
RP11-360P21.2
chr9_+_130890612 1.01 ENST00000443493.1
AL590708.2
chr4_-_87278857 1.00 ENST00000509464.1
ENST00000511167.1
mitogen-activated protein kinase 10
chr2_-_183387064 1.00 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr6_+_123317116 1.00 ENST00000275162.5
clavesin 2
chr2_-_113542063 0.99 ENST00000263339.3
interleukin 1, alpha
chr2_+_210444298 0.97 ENST00000445941.1
microtubule-associated protein 2
chr9_-_95166976 0.96 ENST00000447356.1
osteoglycin
chr4_-_150736962 0.95 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
chr2_+_166430619 0.95 ENST00000409420.1
cysteine-serine-rich nuclear protein 3
chr6_-_154568551 0.95 ENST00000519190.1
interaction protein for cytohesin exchange factors 1
chr6_-_154567984 0.95 ENST00000517438.1
interaction protein for cytohesin exchange factors 1
chr2_+_166326157 0.94 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
cysteine-serine-rich nuclear protein 3
chr21_-_46424517 0.94 ENST00000422199.1
long intergenic non-protein coding RNA 162
chr7_-_107443652 0.94 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
solute carrier family 26 (anion exchanger), member 3
chr6_-_50016364 0.93 ENST00000322246.4
defensin, beta 112
chr18_-_11148587 0.93 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
piezo-type mechanosensitive ion channel component 2
chr3_-_169587621 0.92 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
leucine rich repeat containing 31
chr12_+_52056548 0.92 ENST00000545061.1
ENST00000355133.3
sodium channel, voltage gated, type VIII, alpha subunit
chr19_+_52839490 0.92 ENST00000321287.8
zinc finger protein 610
chr12_+_12223867 0.92 ENST00000308721.5
BCL2-like 14 (apoptosis facilitator)
chr20_-_9819674 0.91 ENST00000378429.3
p21 protein (Cdc42/Rac)-activated kinase 7
chr3_+_108308845 0.91 ENST00000479138.1
DAZ interacting zinc finger protein 3
chr11_+_73661364 0.91 ENST00000339764.1
DnaJ (Hsp40) homolog, subfamily B, member 13
chr11_-_84028339 0.90 ENST00000398301.2
discs, large homolog 2 (Drosophila)
chr9_+_105757590 0.90 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr6_-_52705641 0.90 ENST00000370989.2
glutathione S-transferase alpha 5
chr14_+_62585332 0.89 ENST00000554895.1
long intergenic non-protein coding RNA 643
chr17_-_73775839 0.89 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3 histone, family 3B (H3.3B)
chr1_+_156338993 0.89 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
Rh family, B glycoprotein (gene/pseudogene)
chr10_+_90354503 0.88 ENST00000531458.1
lipase, family member J
chr11_-_111944704 0.88 ENST00000532211.1
PIH1 domain containing 2
chr12_+_100897130 0.88 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
nuclear receptor subfamily 1, group H, member 4
chr13_+_76378305 0.87 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr4_-_87281224 0.87 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr15_+_36338242 0.87 ENST00000560056.1
RP11-684B21.1
chr3_+_107364769 0.87 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
bobby sox homolog (Drosophila)
chr6_+_12718497 0.87 ENST00000379348.2
phosphatase and actin regulator 1
chr2_-_233641265 0.86 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
potassium inwardly-rectifying channel, subfamily J, member 13
chr15_+_45028719 0.85 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
tripartite motif containing 69
chr15_+_65822756 0.85 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
protein tyrosine phosphatase-like A domain containing 1
chr5_-_177207634 0.85 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr5_+_167181917 0.84 ENST00000519204.1
teneurin transmembrane protein 2
chr11_-_40315640 0.84 ENST00000278198.2
leucine rich repeat containing 4C
chr9_-_74675521 0.83 ENST00000377024.3
chromosome 9 open reading frame 57

Network of associatons between targets according to the STRING database.

First level regulatory network of CDC5L

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.9 2.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.6 1.9 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.6 3.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.6 1.7 GO:0048174 negative regulation of short-term neuronal synaptic plasticity(GO:0048174)
0.5 1.6 GO:0048627 myoblast development(GO:0048627)
0.5 4.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.4 1.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 1.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.4 2.3 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.4 3.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3 0.9 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 5.8 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.3 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.3 1.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 1.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 3.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.3 GO:0060005 vestibular reflex(GO:0060005)
0.2 0.6 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 0.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 0.5 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2 0.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 1.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.7 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 2.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 0.7 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 0.8 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.5 GO:0006533 aspartate catabolic process(GO:0006533)
0.2 2.0 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 2.3 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 0.6 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.7 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.5 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 2.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 2.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 2.7 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.0 GO:0035234 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) ectopic germ cell programmed cell death(GO:0035234)
0.1 0.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 2.2 GO:0006527 arginine catabolic process(GO:0006527) negative regulation of cellular response to hypoxia(GO:1900038)
0.1 2.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 2.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 2.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.3 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 1.1 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.1 2.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 4.4 GO:0046710 GDP metabolic process(GO:0046710) receptor localization to synapse(GO:0097120)
0.1 0.6 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.9 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.9 GO:0015671 oxygen transport(GO:0015671)
0.1 1.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 2.8 GO:0006833 water transport(GO:0006833)
0.1 0.3 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 1.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 4.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 1.3 GO:0097264 self proteolysis(GO:0097264)
0.1 2.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.7 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 1.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.6 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 1.3 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.8 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 2.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 4.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.2 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 1.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.8 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 4.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 1.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 1.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.4 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 2.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 1.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.0 3.8 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.5 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.9 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:1901731 protein secretion by platelet(GO:0070560) positive regulation of platelet aggregation(GO:1901731)
0.0 0.9 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 2.3 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.8 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 2.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 1.1 GO:0008380 RNA splicing(GO:0008380)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.7 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 8.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 2.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 3.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.4 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.3 GO:1901673 regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.4 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.4 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.0 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.2 GO:0070989 oxidative demethylation(GO:0070989)
0.0 2.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.8 GO:0044305 calyx of Held(GO:0044305)
0.4 4.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 3.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 1.7 GO:0032127 dense core granule membrane(GO:0032127)
0.3 0.9 GO:0033150 cytoskeletal calyx(GO:0033150)
0.3 3.7 GO:0036157 outer dynein arm(GO:0036157)
0.3 1.1 GO:0030849 autosome(GO:0030849)
0.3 0.8 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 1.6 GO:0005846 nuclear cap binding complex(GO:0005846)
0.2 5.7 GO:0005916 fascia adherens(GO:0005916)
0.2 2.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 2.6 GO:0005883 neurofilament(GO:0005883)
0.1 3.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 3.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 0.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 2.5 GO:0043194 axon initial segment(GO:0043194)
0.1 1.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 3.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 4.5 GO:0030286 dynein complex(GO:0030286)
0.0 1.4 GO:0042599 lamellar body(GO:0042599)
0.0 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 1.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.6 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 10.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 9.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 2.3 GO:0031514 motile cilium(GO:0031514)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 1.2 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.6 1.9 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.6 1.7 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.6 2.3 GO:0005042 netrin receptor activity(GO:0005042)
0.5 5.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 1.8 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 2.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.3 9.6 GO:0002162 dystroglycan binding(GO:0002162)
0.2 3.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 2.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0046848 hydroxyapatite binding(GO:0046848)
0.2 0.9 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 1.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 1.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.6 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 2.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 4.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 1.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 2.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 1.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 5.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 2.8 GO:0015250 water channel activity(GO:0015250)
0.2 1.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0016499 orexin receptor activity(GO:0016499)
0.1 1.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 3.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.6 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 1.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 2.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 3.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 2.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 3.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 3.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.7 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.6 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 2.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 4.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.6 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 1.1 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 2.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.5 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 1.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 2.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 2.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 3.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 1.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 3.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 2.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 5.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 4.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 5.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 6.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 6.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 4.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME OPSINS Genes involved in Opsins
0.0 1.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 3.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 3.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation