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Illumina Body Map 2, young vs old

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Results for CDX2

Z-value: 0.16

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Transcription factors associated with CDX2

Gene Symbol Gene ID Gene Info
CDX2
ENSG00000165556.9 caudal type homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX2hg19_v2_chr13_-_28545276_28545276-0.291.1e-01Click!

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_105937068 1.67 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_-_237167718 1.66 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chrX_+_105936982 1.60 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr22_+_32455111 1.59 ENST00000543737.1
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_+_39944025 1.33 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr12_-_112443767 1.26 ENST00000550233.1
ENST00000546962.1
ENST00000550800.2
TMEM116
transmembrane protein 116
chr10_-_94301107 1.26 ENST00000436178.1
IDE
insulin-degrading enzyme
chr12_-_112443830 1.26 ENST00000550037.1
ENST00000549425.1
TMEM116
transmembrane protein 116
chrM_+_10464 1.17 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr10_-_103599591 1.14 ENST00000348850.5
KCNIP2
Kv channel interacting protein 2
chr17_+_58018269 1.11 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr6_+_111408698 1.07 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr1_+_74701062 0.90 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr5_+_36608280 0.90 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_72649763 0.89 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr10_-_24770632 0.88 ENST00000596413.1
AL353583.1
AL353583.1
chr22_+_17956618 0.88 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr7_+_138915102 0.88 ENST00000486663.1
UBN2
ubinuclein 2
chrX_-_15619076 0.88 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr9_-_98189055 0.87 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr11_+_112047087 0.87 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr6_+_53948328 0.85 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr5_+_36606700 0.83 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_155484155 0.82 ENST00000509493.1
FGB
fibrinogen beta chain
chr2_-_40657397 0.81 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_-_108672742 0.79 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr6_+_78400375 0.79 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr4_-_140222358 0.78 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr11_-_3663212 0.78 ENST00000397067.3
ART5
ADP-ribosyltransferase 5
chr3_-_108672609 0.78 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr4_+_155484103 0.77 ENST00000302068.4
FGB
fibrinogen beta chain
chr3_-_18480173 0.75 ENST00000414509.1
SATB1
SATB homeobox 1
chr9_-_28670283 0.75 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr6_+_12958137 0.70 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr1_+_154401791 0.69 ENST00000476006.1
IL6R
interleukin 6 receptor
chr17_+_45286706 0.69 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr7_+_35756092 0.69 ENST00000458087.3
AC018647.3
AC018647.3
chr20_-_36152914 0.68 ENST00000397131.1
BLCAP
bladder cancer associated protein
chr3_-_18480260 0.66 ENST00000454909.2
SATB1
SATB homeobox 1
chrM_+_10053 0.63 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr6_+_47666275 0.62 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr1_+_52682052 0.62 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr2_-_122262593 0.62 ENST00000418989.1
CLASP1
cytoplasmic linker associated protein 1
chr4_+_146539415 0.59 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr10_-_115614127 0.58 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chrX_-_30993201 0.58 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_+_115614370 0.58 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr6_+_143447322 0.55 ENST00000458219.1
AIG1
androgen-induced 1
chr3_+_125687987 0.53 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr6_+_25754927 0.53 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr22_+_41956767 0.53 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr7_+_80275663 0.53 ENST00000413265.1
CD36
CD36 molecule (thrombospondin receptor)
chr20_-_7921090 0.51 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr20_+_42984330 0.50 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr7_+_35756186 0.50 ENST00000430518.1
AC018647.3
AC018647.3
chr10_-_129691195 0.50 ENST00000368671.3
CLRN3
clarin 3
chr16_-_66907139 0.50 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr2_-_51259292 0.50 ENST00000401669.2
NRXN1
neurexin 1
chr4_-_169239921 0.50 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr18_-_52989217 0.50 ENST00000570287.2
TCF4
transcription factor 4
chr13_-_50020554 0.49 ENST00000400396.1
AL136218.1
Sarcoma antigen NY-SAR-79; Uncharacterized protein
chr2_-_51259229 0.49 ENST00000405472.3
NRXN1
neurexin 1
chr3_-_155011483 0.49 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr12_+_32687221 0.48 ENST00000525053.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_+_109685630 0.48 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr11_-_93271058 0.48 ENST00000527149.1
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr16_+_25123148 0.48 ENST00000570981.1
LCMT1
leucine carboxyl methyltransferase 1
chr5_-_148442584 0.47 ENST00000394358.2
ENST00000512049.1
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr1_-_160231451 0.46 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr13_-_62001982 0.46 ENST00000409186.1
PCDH20
protocadherin 20
chr16_+_19619083 0.45 ENST00000538552.1
C16orf62
chromosome 16 open reading frame 62
chr7_+_80275621 0.45 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr17_-_80797886 0.44 ENST00000572562.1
ZNF750
zinc finger protein 750
chr7_-_107204918 0.43 ENST00000297135.3
COG5
component of oligomeric golgi complex 5
chr7_+_80275953 0.43 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr7_+_80275752 0.43 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr10_+_60759378 0.41 ENST00000432535.1
LINC00844
long intergenic non-protein coding RNA 844
chr11_+_46366918 0.41 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr18_+_68002675 0.41 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr3_-_67705006 0.40 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
SUCLG2
succinate-CoA ligase, GDP-forming, beta subunit
chr2_+_120687335 0.40 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr18_+_3252206 0.40 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_+_12524965 0.40 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr6_-_138833630 0.40 ENST00000533765.1
NHSL1
NHS-like 1
chr12_+_19389814 0.40 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr5_+_98109322 0.39 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr6_+_118869452 0.39 ENST00000357525.5
PLN
phospholamban
chr10_+_24755416 0.38 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr3_+_57875711 0.38 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr11_+_27062860 0.37 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_+_25123041 0.37 ENST00000399069.3
ENST00000380966.4
LCMT1
leucine carboxyl methyltransferase 1
chr4_-_48683188 0.37 ENST00000505759.1
FRYL
FRY-like
chr11_+_22688150 0.37 ENST00000454584.2
GAS2
growth arrest-specific 2
chr1_+_89246647 0.37 ENST00000544045.1
PKN2
protein kinase N2
chr16_+_56782118 0.37 ENST00000566678.1
NUP93
nucleoporin 93kDa
chr2_+_210443993 0.37 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr17_-_39646116 0.36 ENST00000328119.6
KRT36
keratin 36
chr18_+_3252265 0.36 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_45686457 0.36 ENST00000441606.2
ANO6
anoctamin 6
chr1_+_220267429 0.36 ENST00000366922.1
ENST00000302637.5
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr8_+_38662960 0.35 ENST00000524193.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr10_+_76871229 0.35 ENST00000372690.3
SAMD8
sterile alpha motif domain containing 8
chr14_-_72458326 0.35 ENST00000542853.1
AC005477.1
AC005477.1
chr10_-_127505167 0.35 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr12_-_95774672 0.35 ENST00000549961.1
RP11-167N24.6
Uncharacterized protein
chr9_+_2029019 0.35 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_171757346 0.33 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
FNDC3B
fibronectin type III domain containing 3B
chr3_-_196911002 0.33 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr5_-_58295712 0.33 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_35270552 0.33 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr9_-_95055923 0.32 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr10_+_85933494 0.31 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr6_+_143759575 0.30 ENST00000595616.1
AL031320.1
AL031320.1
chr14_+_53173910 0.30 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr7_+_135710494 0.30 ENST00000440744.2
AC024084.1
AC024084.1
chr15_+_67835517 0.29 ENST00000395476.2
MAP2K5
mitogen-activated protein kinase kinase 5
chr2_-_176046391 0.29 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr16_-_25122735 0.28 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr12_-_118796971 0.28 ENST00000542902.1
TAOK3
TAO kinase 3
chrX_-_135962923 0.27 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr10_-_5660118 0.27 ENST00000427341.1
RP11-336A10.4
RP11-336A10.4
chr14_+_53173890 0.27 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr3_+_57875738 0.27 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr6_+_158733692 0.26 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr11_+_12302492 0.26 ENST00000533534.1
MICALCL
MICAL C-terminal like
chr2_-_95787738 0.26 ENST00000272418.2
MRPS5
mitochondrial ribosomal protein S5
chr9_-_130889990 0.26 ENST00000449878.1
PTGES2
prostaglandin E synthase 2
chr9_-_73029540 0.25 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr11_+_22688615 0.25 ENST00000533363.1
GAS2
growth arrest-specific 2
chr20_-_25320367 0.25 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr3_+_41241596 0.24 ENST00000450969.1
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr20_-_56647116 0.24 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1
RP13-379L11.1
chr5_+_72143988 0.24 ENST00000506351.2
TNPO1
transportin 1
chr11_+_89764274 0.24 ENST00000448984.1
ENST00000432771.1
TRIM49C
tripartite motif containing 49C
chr8_+_107738343 0.24 ENST00000521592.1
OXR1
oxidation resistance 1
chr6_-_133035185 0.24 ENST00000367928.4
VNN1
vanin 1
chr1_-_54355430 0.24 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr1_-_198990166 0.23 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr15_-_41836441 0.23 ENST00000567866.1
ENST00000561603.1
ENST00000304330.4
ENST00000566863.1
RPAP1
RNA polymerase II associated protein 1
chr2_-_8977714 0.23 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
KIDINS220
kinase D-interacting substrate, 220kDa
chr13_+_24144509 0.23 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr9_-_37384431 0.23 ENST00000452923.1
RP11-397D12.4
RP11-397D12.4
chr9_-_95055956 0.23 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr12_-_10962767 0.23 ENST00000240691.2
TAS2R9
taste receptor, type 2, member 9
chr4_+_95972822 0.23 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr2_+_108863651 0.22 ENST00000329106.2
ENST00000376700.1
SULT1C3
sulfotransferase family, cytosolic, 1C, member 3
chr20_+_2276639 0.22 ENST00000381458.5
TGM3
transglutaminase 3
chr19_+_21106028 0.21 ENST00000597314.1
ENST00000601924.1
ZNF85
zinc finger protein 85
chr12_-_76879852 0.21 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr6_-_26189304 0.21 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr8_+_85095013 0.21 ENST00000522613.1
RALYL
RALY RNA binding protein-like
chr3_+_15045419 0.21 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chrX_+_107037451 0.20 ENST00000372379.2
NCBP2L
nuclear cap binding protein subunit 2-like
chrX_-_135962876 0.20 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr15_+_86686953 0.20 ENST00000421325.2
AGBL1
ATP/GTP binding protein-like 1
chr5_-_148033693 0.20 ENST00000377888.3
ENST00000360693.3
HTR4
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr2_+_210444298 0.19 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr2_+_208423840 0.19 ENST00000539789.1
CREB1
cAMP responsive element binding protein 1
chr7_+_137761167 0.18 ENST00000432161.1
AKR1D1
aldo-keto reductase family 1, member D1
chr12_+_1800179 0.18 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr9_-_95056010 0.18 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr14_+_35514323 0.17 ENST00000555211.1
FAM177A1
family with sequence similarity 177, member A1
chr7_+_6121296 0.17 ENST00000428901.1
AC004895.4
AC004895.4
chr11_+_71900703 0.17 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr5_-_16738451 0.17 ENST00000274203.9
ENST00000515803.1
MYO10
myosin X
chr12_+_64173583 0.17 ENST00000261234.6
TMEM5
transmembrane protein 5
chr1_+_46152886 0.17 ENST00000372025.4
TMEM69
transmembrane protein 69
chr1_+_53480598 0.17 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr8_+_52730143 0.17 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr8_-_86162077 0.16 ENST00000551479.1
RP11-219B4.6
Uncharacterized protein
chr12_-_72104152 0.16 ENST00000549710.1
RP11-498M15.1
RP11-498M15.1
chr3_-_156534754 0.16 ENST00000472943.1
ENST00000473352.1
LINC00886
long intergenic non-protein coding RNA 886
chr17_+_68071389 0.16 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr10_+_47657581 0.16 ENST00000441923.2
ANTXRL
anthrax toxin receptor-like
chr9_-_86571628 0.16 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr20_+_56964169 0.16 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr12_+_56546223 0.16 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr6_+_134274322 0.15 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr21_-_28338732 0.15 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr5_-_111093167 0.15 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr2_+_187371440 0.15 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr9_+_134065506 0.15 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr3_-_123710893 0.15 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1
rhophilin associated tail protein 1
chr8_+_145215928 0.15 ENST00000528919.1
MROH1
maestro heat-like repeat family member 1
chr6_-_127840453 0.14 ENST00000556132.1
SOGA3
SOGA family member 3
chr2_+_151485403 0.14 ENST00000413247.1
ENST00000423428.1
ENST00000427615.1
ENST00000443811.1
AC104777.4
AC104777.4
chr2_+_233415363 0.14 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chr8_-_143859197 0.14 ENST00000395192.2
LYNX1
Ly6/neurotoxin 1
chr14_+_52456327 0.13 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr7_-_111032971 0.13 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_65996599 0.13 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr2_+_208423891 0.13 ENST00000448277.1
ENST00000457101.1
CREB1
cAMP responsive element binding protein 1
chr4_+_26165074 0.13 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr12_+_56546363 0.13 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr4_+_70894130 0.13 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr12_-_118796910 0.13 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr16_+_66613351 0.13 ENST00000379486.2
ENST00000268595.2
CMTM2
CKLF-like MARVEL transmembrane domain containing 2
chr19_-_53636125 0.12 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
ZNF415
zinc finger protein 415
chr2_+_109204743 0.12 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_+_13885252 0.12 ENST00000221576.4
C19orf53
chromosome 19 open reading frame 53

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0042214 terpene metabolic process(GO:0042214)
0.3 0.8 GO:0006481 C-terminal protein methylation(GO:0006481)
0.3 1.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 3.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.8 GO:1901143 insulin catabolic process(GO:1901143)
0.2 1.6 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.2 0.9 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) receptor-mediated virion attachment to host cell(GO:0046813)
0.2 0.7 GO:0002384 hepatic immune response(GO:0002384)
0.2 1.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.7 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.8 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.6 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.4 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 1.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 1.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 1.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 0.4 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.5 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 1.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0044691 tooth eruption(GO:0044691)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.0 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.9 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 1.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) vascular wound healing(GO:0061042)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031592 centrosomal corona(GO:0031592)
0.1 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 1.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 2.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.8 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0031626 beta-endorphin binding(GO:0031626)
0.3 0.9 GO:1902271 D3 vitamins binding(GO:1902271)
0.3 0.8 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.3 1.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.3 1.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.7 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.5 GO:0052853 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 1.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.8 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.1 1.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.4 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells