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Illumina Body Map 2, young vs old

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Results for CREB3L2

Z-value: 0.39

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Transcription factors associated with CREB3L2

Gene Symbol Gene ID Gene Info
CREB3L2
ENSG00000182158.10 cAMP responsive element binding protein 3 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3L2hg19_v2_chr7_-_137686791_137686821-0.028.9e-01Click!

Activity profile of CREB3L2 motif

Sorted Z-values of CREB3L2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_61584026 4.06 ENST00000370351.4
ENST00000370349.3
SLC17A9
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr20_+_61584398 3.39 ENST00000411611.1
SLC17A9
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr19_-_4670345 2.49 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr20_-_22559211 2.39 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr17_-_26695013 2.27 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr17_-_26694979 2.06 ENST00000438614.1
VTN
vitronectin
chr9_+_96928516 1.83 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr12_-_49318715 1.83 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr14_+_100789669 1.81 ENST00000361529.3
ENST00000557052.1
SLC25A47
solute carrier family 25, member 47
chr5_+_34656569 1.76 ENST00000428746.2
RAI14
retinoic acid induced 14
chr5_+_34656529 1.66 ENST00000513974.1
ENST00000512629.1
RAI14
retinoic acid induced 14
chr1_-_32801825 1.64 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr5_+_34656331 1.60 ENST00000265109.3
RAI14
retinoic acid induced 14
chr20_-_61051026 1.59 ENST00000252997.2
GATA5
GATA binding protein 5
chr10_+_102106829 1.54 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr7_-_100171270 1.54 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr14_-_106174960 1.52 ENST00000390547.2
IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_106054659 1.44 ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr20_+_31595406 1.41 ENST00000170150.3
BPIFB2
BPI fold containing family B, member 2
chr10_+_23216944 1.41 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
ARMC3
armadillo repeat containing 3
chr8_+_22225041 1.41 ENST00000289952.5
ENST00000524285.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr18_+_56806701 1.40 ENST00000587834.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr2_+_217498105 1.39 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr22_+_22681656 1.39 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr9_+_130478345 1.38 ENST00000373289.3
ENST00000393748.4
TTC16
tetratricopeptide repeat domain 16
chr3_+_122785895 1.36 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr8_+_22224760 1.32 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr19_-_11688500 1.32 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr20_-_2821271 1.31 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr5_-_138725594 1.30 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr18_+_56807096 1.30 ENST00000588875.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr18_+_9708162 1.29 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr19_-_42759300 1.26 ENST00000222329.4
ERF
Ets2 repressor factor
chr15_+_89181974 1.25 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_151561506 1.25 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr10_+_23217006 1.24 ENST00000376528.4
ENST00000447081.1
ARMC3
armadillo repeat containing 3
chr17_+_72270429 1.24 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr2_-_85108164 1.20 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr22_+_44568825 1.20 ENST00000422871.1
PARVG
parvin, gamma
chr5_-_138725560 1.20 ENST00000412103.2
ENST00000457570.2
MZB1
marginal zone B and B1 cell-specific protein
chr18_-_3013307 1.20 ENST00000584294.1
LPIN2
lipin 2
chr22_+_38864041 1.16 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr14_+_101293687 1.16 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr15_+_58724184 1.15 ENST00000433326.2
LIPC
lipase, hepatic
chr10_+_112257596 1.14 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr2_+_198365095 1.12 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr15_+_89182156 1.12 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr10_+_89419370 1.11 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr21_+_45875354 1.06 ENST00000291592.4
LRRC3
leucine rich repeat containing 3
chr3_+_184098065 1.06 ENST00000348986.3
CHRD
chordin
chr5_+_34656450 1.06 ENST00000514527.1
RAI14
retinoic acid induced 14
chr2_-_85108363 1.05 ENST00000335459.5
TRABD2A
TraB domain containing 2A
chr6_+_151561085 1.05 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_85108240 1.05 ENST00000409133.1
TRABD2A
TraB domain containing 2A
chr19_-_47164386 1.02 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr5_+_176730769 1.01 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr1_-_27240455 0.99 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr6_-_7911042 0.98 ENST00000379757.4
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr15_+_89182178 0.96 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_+_37455536 0.96 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr6_-_136871957 0.96 ENST00000354570.3
MAP7
microtubule-associated protein 7
chr17_+_48450575 0.95 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr7_+_29603394 0.95 ENST00000319694.2
PRR15
proline rich 15
chr11_+_120081475 0.94 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr1_+_1567474 0.93 ENST00000356026.5
MMP23B
matrix metallopeptidase 23B
chr3_-_123603137 0.91 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK
myosin light chain kinase
chr7_-_6523755 0.89 ENST00000436575.1
ENST00000258739.4
DAGLB
KDELR2
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr3_-_178789220 0.89 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr21_-_18985158 0.85 ENST00000339775.6
BTG3
BTG family, member 3
chr1_-_42921915 0.83 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr15_-_52404921 0.82 ENST00000561198.1
ENST00000260442.3
BCL2L10
BCL2-like 10 (apoptosis facilitator)
chr15_+_62359175 0.82 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr21_-_40720995 0.81 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr1_-_241520525 0.80 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr8_+_56014949 0.80 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr19_+_49458107 0.78 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr12_+_121416489 0.78 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr21_-_18985230 0.78 ENST00000457956.1
ENST00000348354.6
BTG3
BTG family, member 3
chr6_-_32811771 0.76 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr20_-_4795747 0.76 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr7_+_2671568 0.72 ENST00000258796.7
TTYH3
tweety family member 3
chr19_+_12305895 0.72 ENST00000451691.2
CTD-2666L21.1
CTD-2666L21.1
chr8_-_99129338 0.72 ENST00000520507.1
HRSP12
heat-responsive protein 12
chr16_+_215965 0.72 ENST00000356815.3
HBM
hemoglobin, mu
chrX_+_128913906 0.72 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr19_-_11688951 0.71 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr12_+_121416340 0.70 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr21_-_40720974 0.70 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr16_-_67185117 0.69 ENST00000449549.3
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr19_+_51774540 0.69 ENST00000600813.1
CTD-3187F8.11
CTD-3187F8.11
chr1_+_113392455 0.69 ENST00000456651.1
ENST00000422022.1
RP3-522D1.1
RP3-522D1.1
chr2_-_198364581 0.68 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr13_+_98794810 0.68 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr8_-_99129384 0.68 ENST00000521560.1
ENST00000254878.3
HRSP12
heat-responsive protein 12
chr1_-_11865982 0.67 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_11866207 0.66 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr3_-_57583185 0.66 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr7_+_100464760 0.66 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr1_-_91317072 0.65 ENST00000435649.2
ENST00000443802.1
RP4-665J23.1
RP4-665J23.1
chr1_+_28918712 0.65 ENST00000373826.3
RAB42
RAB42, member RAS oncogene family
chr17_+_74723031 0.64 ENST00000586200.1
METTL23
methyltransferase like 23
chr7_-_121036337 0.64 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
FAM3C
family with sequence similarity 3, member C
chr19_+_11350278 0.63 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr14_-_100070363 0.63 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr20_+_44519948 0.63 ENST00000354880.5
ENST00000191018.5
CTSA
cathepsin A
chr12_+_50355647 0.63 ENST00000293599.6
AQP5
aquaporin 5
chr3_-_57583052 0.63 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr11_+_45944190 0.62 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B
glycosyltransferase-like 1B
chr7_-_98030360 0.62 ENST00000005260.8
BAIAP2L1
BAI1-associated protein 2-like 1
chr19_+_51774520 0.62 ENST00000595566.1
ENST00000594261.1
CTD-3187F8.11
CTD-3187F8.11
chr2_+_207024306 0.61 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr10_-_97416400 0.60 ENST00000371224.2
ENST00000371221.3
ALDH18A1
aldehyde dehydrogenase 18 family, member A1
chr22_+_39916558 0.60 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr10_+_103892787 0.60 ENST00000278070.2
ENST00000413464.2
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chrX_-_48326764 0.60 ENST00000413668.1
ENST00000441948.1
SLC38A5
solute carrier family 38, member 5
chr3_-_57583130 0.60 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chrX_+_131157290 0.59 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr20_+_44520009 0.58 ENST00000607482.1
ENST00000372459.2
CTSA
cathepsin A
chr11_-_118972575 0.58 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr9_+_117350009 0.56 ENST00000374050.3
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr15_-_79383102 0.56 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr19_-_39805976 0.56 ENST00000248668.4
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr12_+_121416437 0.55 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A
HNF1 homeobox A
chr17_-_74722536 0.55 ENST00000585429.1
JMJD6
jumonji domain containing 6
chrX_-_48326683 0.55 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chrX_+_131157322 0.54 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr2_+_46926048 0.54 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr20_-_17662878 0.54 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1
ribosome binding protein 1
chrX_+_55246771 0.54 ENST00000289619.5
ENST00000374955.3
PAGE5
P antigen family, member 5 (prostate associated)
chrX_+_153686614 0.53 ENST00000369682.3
PLXNA3
plexin A3
chr2_-_65357225 0.53 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A
RAB1A, member RAS oncogene family
chr10_-_127464390 0.53 ENST00000368808.3
MMP21
matrix metallopeptidase 21
chrX_+_55246818 0.53 ENST00000374952.1
PAGE5
P antigen family, member 5 (prostate associated)
chr5_+_133984462 0.52 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr11_-_57282349 0.51 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr3_+_51428704 0.51 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr7_-_6523688 0.50 ENST00000490996.1
KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr7_+_16793160 0.49 ENST00000262067.4
TSPAN13
tetraspanin 13
chr19_-_40730820 0.49 ENST00000513948.1
CNTD2
cyclin N-terminal domain containing 2
chr2_+_113403434 0.48 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr20_-_44519839 0.46 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr20_-_2821756 0.46 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr2_+_241526126 0.46 ENST00000391984.2
ENST00000391982.2
ENST00000404753.3
ENST00000270364.7
ENST00000352879.4
ENST00000354082.4
CAPN10
calpain 10
chr17_+_39969183 0.45 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr1_-_111746966 0.45 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr8_-_143696833 0.45 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr11_+_32112431 0.45 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr17_+_74722912 0.44 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23
methyltransferase like 23
chr5_+_68710906 0.43 ENST00000325631.5
ENST00000454295.2
MARVELD2
MARVEL domain containing 2
chr19_-_13030071 0.43 ENST00000293695.7
SYCE2
synaptonemal complex central element protein 2
chr6_+_32811861 0.42 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr6_-_28891709 0.42 ENST00000377194.3
ENST00000377199.3
TRIM27
tripartite motif containing 27
chr5_-_158636512 0.42 ENST00000424310.2
RNF145
ring finger protein 145
chr8_-_144679264 0.41 ENST00000531953.1
ENST00000526133.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr22_-_35627045 0.41 ENST00000423311.1
CTA-714B7.5
CTA-714B7.5
chr15_-_52030293 0.41 ENST00000560491.1
ENST00000267838.3
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr7_-_8301869 0.40 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr6_+_167684651 0.40 ENST00000503433.1
UNC93A
unc-93 homolog A (C. elegans)
chr4_+_186347388 0.40 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr1_-_1167411 0.39 ENST00000263741.7
SDF4
stromal cell derived factor 4
chr1_-_11866034 0.39 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_-_155572164 0.38 ENST00000392845.3
ENST00000359479.3
SLC33A1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr5_+_68711023 0.38 ENST00000515844.1
MARVELD2
MARVEL domain containing 2
chr22_-_18257178 0.38 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr10_+_131265443 0.37 ENST00000306010.7
MGMT
O-6-methylguanine-DNA methyltransferase
chr21_-_28215332 0.37 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr2_+_201676908 0.37 ENST00000409226.1
ENST00000452790.2
BZW1
basic leucine zipper and W2 domains 1
chr11_-_777467 0.37 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
PDDC1
Parkinson disease 7 domain containing 1
chr5_-_176730676 0.37 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr11_+_67159416 0.36 ENST00000307980.2
ENST00000544620.1
RAD9A
RAD9 homolog A (S. pombe)
chr1_+_180123969 0.36 ENST00000367602.3
ENST00000367600.5
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr9_-_136242956 0.36 ENST00000371989.3
ENST00000485435.2
SURF4
surfeit 4
chr7_-_8302164 0.35 ENST00000447326.1
ENST00000406470.2
ICA1
islet cell autoantigen 1, 69kDa
chr21_+_37442239 0.35 ENST00000530908.1
ENST00000290349.6
ENST00000439427.2
ENST00000399191.3
CBR1
carbonyl reductase 1
chr7_+_23749945 0.35 ENST00000354639.3
ENST00000531170.1
ENST00000444333.2
ENST00000428484.1
STK31
serine/threonine kinase 31
chr9_+_130565147 0.34 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
FPGS
folylpolyglutamate synthase
chr11_+_67776012 0.33 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr6_+_32811885 0.33 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr5_+_152870215 0.32 ENST00000518142.1
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr19_-_44143939 0.32 ENST00000222374.2
CADM4
cell adhesion molecule 4
chr11_-_100999775 0.32 ENST00000263463.5
PGR
progesterone receptor
chr16_-_28074822 0.32 ENST00000395724.3
ENST00000380898.2
ENST00000447459.2
GSG1L
GSG1-like
chr15_-_40213080 0.32 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr16_+_2533020 0.32 ENST00000562105.1
TBC1D24
TBC1 domain family, member 24
chr11_-_111957451 0.32 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr2_+_201676256 0.31 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
BZW1
basic leucine zipper and W2 domains 1
chr4_+_119200215 0.31 ENST00000602573.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr1_+_110162448 0.30 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2
adenosine monophosphate deaminase 2
chr12_+_57623869 0.30 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr7_-_8301682 0.30 ENST00000396675.3
ENST00000430867.1
ICA1
islet cell autoantigen 1, 69kDa
chr10_+_6392278 0.29 ENST00000391437.1
DKFZP667F0711
DKFZP667F0711
chr19_-_10341948 0.29 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr10_-_49459800 0.29 ENST00000305531.3
FRMPD2
FERM and PDZ domain containing 2
chr11_-_61560053 0.28 ENST00000537328.1
TMEM258
transmembrane protein 258
chr1_-_45956822 0.28 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr12_+_57623477 0.28 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_+_228327943 0.28 ENST00000366726.1
ENST00000312726.4
ENST00000366728.2
ENST00000453943.1
ENST00000366723.1
ENST00000366722.1
ENST00000435153.1
ENST00000366721.1
GUK1
guanylate kinase 1
chr6_-_144329384 0.28 ENST00000417959.2
PLAGL1
pleiomorphic adenoma gene-like 1
chr2_-_27341966 0.28 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
CGREF1
cell growth regulator with EF-hand domain 1
chr3_+_51741072 0.25 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.7 2.0 GO:0035623 renal glucose absorption(GO:0035623)
0.7 3.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 1.5 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 2.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.4 1.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.3 1.1 GO:0000103 sulfate assimilation(GO:0000103)
0.3 3.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 0.8 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.3 2.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.7 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.9 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.2 2.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.5 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.2 2.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 2.7 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.1 1.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.5 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 2.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 7.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 2.7 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.6 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 1.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 1.1 GO:0015816 glycine transport(GO:0015816)
0.1 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 1.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.8 GO:0015879 carnitine transport(GO:0015879)
0.0 0.2 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 1.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 1.4 GO:0010226 response to lithium ion(GO:0010226)
0.0 1.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:1903142 C-5 methylation of cytosine(GO:0090116) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 1.9 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:1900016 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307) positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 2.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.4 GO:0009650 UV protection(GO:0009650)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 1.4 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 1.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 1.0 GO:0006970 response to osmotic stress(GO:0006970)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.5 2.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 2.7 GO:0005787 signal peptidase complex(GO:0005787)
0.2 1.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 0.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.7 GO:0044308 axonal spine(GO:0044308)
0.1 0.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:1990037 Lewy body core(GO:1990037)
0.1 1.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.9 GO:0070552 BRISC complex(GO:0070552)
0.1 0.3 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.2 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.7 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 3.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.0 5.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.2 GO:0005655 ribonuclease MRP complex(GO:0000172) nucleolar ribonuclease P complex(GO:0005655)
0.0 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.3 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 5.0 GO:0031301 integral component of organelle membrane(GO:0031301)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.1 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 1.4 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 1.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 1.8 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 1.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 2.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 1.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 0.5 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.6 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.7 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 2.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.1 GO:0045545 syndecan binding(GO:0045545)
0.1 0.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.9 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 2.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 2.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.8 GO:0089720 caspase binding(GO:0089720)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 3.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 4.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 4.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 2.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway