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Illumina Body Map 2, young vs old

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Results for CUX2

Z-value: 0.23

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Transcription factors associated with CUX2

Gene Symbol Gene ID Gene Info
ENSG00000111249.9 cut like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CUX2hg19_v2_chr12_+_111537227_1115372500.714.9e-06Click!

Activity profile of CUX2 motif

Sorted Z-values of CUX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_196912902 5.31 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr17_-_64216748 4.33 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_75100539 4.08 ENST00000420661.2
chromosome 1 open reading frame 173
chr19_-_58864848 3.87 ENST00000263100.3
alpha-1-B glycoprotein
chr3_+_35683651 3.84 ENST00000187397.4
cAMP-regulated phosphoprotein, 21kDa
chr18_+_29171689 3.75 ENST00000237014.3
transthyretin
chr3_+_35721106 3.58 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr4_+_74275057 3.57 ENST00000511370.1
albumin
chr13_-_46679185 3.44 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr1_-_159684371 3.31 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
C-reactive protein, pentraxin-related
chr3_+_52811596 3.17 ENST00000542827.1
ENST00000273283.2
inter-alpha-trypsin inhibitor heavy chain 1
chr13_-_46679144 3.06 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr4_+_69681710 3.06 ENST00000265403.7
ENST00000458688.2
UDP glucuronosyltransferase 2 family, polypeptide B10
chr3_+_35682913 3.04 ENST00000449196.1
cAMP-regulated phosphoprotein, 21kDa
chr3_+_35683775 2.98 ENST00000452563.1
cAMP-regulated phosphoprotein, 21kDa
chr14_-_21056121 2.83 ENST00000557105.1
ENST00000398008.2
ENST00000555841.1
ENST00000443456.2
ENST00000432835.2
ENST00000557503.1
ENST00000398009.2
ENST00000554842.1
ribonuclease, RNase A family, 11 (non-active)
chr5_-_135290705 2.81 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr1_+_57320437 2.81 ENST00000361249.3
complement component 8, alpha polypeptide
chr12_-_78753496 2.81 ENST00000548512.1
RP11-38F22.1
chr12_+_111471828 2.76 ENST00000261726.6
cut-like homeobox 2
chr3_+_35683816 2.68 ENST00000438577.1
cAMP-regulated phosphoprotein, 21kDa
chr2_+_211342432 2.59 ENST00000430249.2
carbamoyl-phosphate synthase 1, mitochondrial
chr14_+_88490894 2.57 ENST00000556033.1
ENST00000553929.1
ENST00000555996.1
ENST00000556673.1
ENST00000557339.1
ENST00000556684.1
long intergenic non-protein coding RNA 1146
chr4_-_72649763 2.50 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr17_-_64225508 2.46 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_187187098 2.42 ENST00000403665.2
ENST00000264692.4
coagulation factor XI
chr5_+_173472607 2.31 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr8_+_77593448 2.26 ENST00000521891.2
zinc finger homeobox 4
chr1_+_161190160 2.23 ENST00000594609.1
Uncharacterized protein
chr3_+_35721182 2.16 ENST00000413378.1
ENST00000417925.1
cAMP-regulated phosphoprotein, 21kDa
chr11_-_35440796 2.09 ENST00000278379.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_-_96829246 2.06 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr10_+_95517660 2.06 ENST00000371413.3
leucine-rich, glioma inactivated 1
chr10_+_95517616 2.05 ENST00000371418.4
leucine-rich, glioma inactivated 1
chr19_-_16008880 2.04 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr7_+_151653464 2.00 ENST00000431418.2
ENST00000392800.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr3_-_10452359 1.97 ENST00000452124.1
ATPase, Ca++ transporting, plasma membrane 2
chr8_+_77593474 1.96 ENST00000455469.2
ENST00000050961.6
zinc finger homeobox 4
chr11_-_35440579 1.95 ENST00000606205.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_49931818 1.91 ENST00000322066.3
defensin, beta 114
chr10_+_95517566 1.86 ENST00000542308.1
leucine-rich, glioma inactivated 1
chr19_+_45409011 1.81 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr3_-_148939598 1.76 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr13_-_62001982 1.71 ENST00000409186.1
protocadherin 20
chr20_-_22566089 1.70 ENST00000377115.4
forkhead box A2
chr15_+_51973680 1.66 ENST00000542355.2
secretogranin III
chr16_-_48281305 1.64 ENST00000356608.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr2_+_108863651 1.64 ENST00000329106.2
ENST00000376700.1
sulfotransferase family, cytosolic, 1C, member 3
chr3_-_108836977 1.64 ENST00000232603.5
MORC family CW-type zinc finger 1
chr22_-_50523843 1.63 ENST00000535444.1
ENST00000431262.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr19_+_3224700 1.59 ENST00000292672.2
ENST00000541430.2
CUGBP, Elav-like family member 5
chr3_-_42452050 1.59 ENST00000441172.1
ENST00000287748.3
lysozyme-like 4
chr11_-_49230184 1.58 ENST00000340334.7
ENST00000256999.2
folate hydrolase (prostate-specific membrane antigen) 1
chr12_-_10151773 1.57 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr11_+_58706944 1.56 ENST00000532726.1
glycine-N-acyltransferase-like 1
chr1_+_50571949 1.54 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr8_+_22601 1.51 ENST00000522481.3
ENST00000518652.1
Uncharacterized protein
chr11_-_49230144 1.47 ENST00000343844.4
folate hydrolase (prostate-specific membrane antigen) 1
chr12_+_20968608 1.46 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr4_+_187187337 1.45 ENST00000492972.2
coagulation factor XI
chrX_+_55246818 1.45 ENST00000374952.1
P antigen family, member 5 (prostate associated)
chr1_+_196857144 1.45 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr5_-_135290651 1.45 ENST00000522943.1
ENST00000514447.2
leukocyte cell-derived chemotaxin 2
chr9_-_27297126 1.43 ENST00000380031.1
ENST00000537675.1
ENST00000380032.3
equatorin, sperm acrosome associated
chr1_-_169733789 1.42 ENST00000454271.1
ENST00000609271.1
RP1-117P20.3
selectin E
chr3_+_53528659 1.41 ENST00000350061.5
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr3_+_35721130 1.41 ENST00000432450.1
cAMP-regulated phosphoprotein, 21kDa
chr1_+_152850787 1.41 ENST00000368765.3
sperm mitochondria-associated cysteine-rich protein
chr6_+_73076432 1.40 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr8_-_86290333 1.38 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr3_+_63428752 1.37 ENST00000295894.5
synaptoporin
chr19_-_36297632 1.36 ENST00000588266.2
proline dehydrogenase (oxidase) 2
chr1_-_197036364 1.36 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr4_-_139051839 1.36 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
long intergenic non-protein coding RNA 616
chr4_-_34271356 1.35 ENST00000514877.1
RP11-548L20.1
chr15_+_51973708 1.34 ENST00000558709.1
secretogranin III
chr15_-_79383102 1.33 ENST00000558480.2
ENST00000419573.3
Ras protein-specific guanine nucleotide-releasing factor 1
chr4_-_176733377 1.33 ENST00000505375.1
glycoprotein M6A
chr7_-_121944491 1.32 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr3_+_181429704 1.31 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr22_+_51176624 1.29 ENST00000216139.5
ENST00000529621.1
acrosin
chr3_+_134514093 1.29 ENST00000398015.3
EPH receptor B1
chr2_+_234959323 1.29 ENST00000373368.1
ENST00000168148.3
secreted phosphoprotein 2, 24kDa
chr12_-_133186983 1.28 ENST00000544018.2
leucine rich colipase-like 1
chr1_-_23340400 1.25 ENST00000440767.2
chromosome 1 open reading frame 234
chr1_-_68915610 1.25 ENST00000262340.5
retinal pigment epithelium-specific protein 65kDa
chr9_+_74729511 1.24 ENST00000545168.1
guanine deaminase
chr2_-_220174166 1.24 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
protein tyrosine phosphatase, receptor type, N
chr5_-_146302078 1.23 ENST00000508545.2
protein phosphatase 2, regulatory subunit B, beta
chr1_-_106161540 1.23 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
RP11-251P6.1
chr1_+_207262627 1.23 ENST00000391923.1
complement component 4 binding protein, beta
chr12_-_45269430 1.23 ENST00000395487.2
NEL-like 2 (chicken)
chr11_-_89653576 1.22 ENST00000420869.1
tripartite motif containing 49D1
chr6_-_154677866 1.22 ENST00000367220.4
interaction protein for cytohesin exchange factors 1
chr15_+_54901540 1.22 ENST00000539562.2
unc-13 homolog C (C. elegans)
chr5_-_110062384 1.22 ENST00000429839.2
transmembrane protein 232
chr3_-_172859017 1.22 ENST00000351008.3
spermatogenesis associated 16
chr22_-_50523760 1.21 ENST00000395876.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr20_-_52612705 1.21 ENST00000434986.2
breast carcinoma amplified sequence 1
chr11_-_57158109 1.20 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr11_-_110561721 1.19 ENST00000357139.3
Rho GTPase activating protein 20
chr8_-_86253888 1.19 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr2_+_211421262 1.19 ENST00000233072.5
carbamoyl-phosphate synthase 1, mitochondrial
chr17_+_43922241 1.18 ENST00000329196.5
signal peptide peptidase like 2C
chr6_-_49834240 1.18 ENST00000335847.4
cysteine-rich secretory protein 1
chrX_+_55246771 1.18 ENST00000289619.5
ENST00000374955.3
P antigen family, member 5 (prostate associated)
chr21_-_22175341 1.17 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
long intergenic non-protein coding RNA 320
chr1_-_76398077 1.16 ENST00000284142.6
ankyrin repeat and SOCS box containing 17
chr6_-_49834209 1.16 ENST00000507853.1
cysteine-rich secretory protein 1
chr8_+_104892639 1.16 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr13_+_78315528 1.16 ENST00000496045.1
SLAIN motif family, member 1
chr8_-_38008783 1.15 ENST00000276449.4
steroidogenic acute regulatory protein
chr12_+_75728419 1.13 ENST00000378695.4
ENST00000312442.2
GLI pathogenesis-related 1 like 1
chr3_+_26735991 1.13 ENST00000456208.2
leucine rich repeat containing 3B
chr6_-_154677900 1.12 ENST00000265198.4
ENST00000520261.1
interaction protein for cytohesin exchange factors 1
chr10_+_51549498 1.12 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr1_+_240255166 1.11 ENST00000319653.9
formin 2
chr3_-_165555200 1.10 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr5_-_55412774 1.09 ENST00000434982.2
ankyrin repeat domain 55
chr10_+_5238793 1.09 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr7_-_96132835 1.07 ENST00000356686.1
chromosome 7 open reading frame 76
chr22_-_50523807 1.07 ENST00000442311.1
ENST00000538737.1
megalencephalic leukoencephalopathy with subcortical cysts 1
chrX_-_80457385 1.07 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chr14_-_47812321 1.07 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MAM domain containing glycosylphosphatidylinositol anchor 2
chr11_-_49230084 1.05 ENST00000356696.3
folate hydrolase (prostate-specific membrane antigen) 1
chr4_+_71263599 1.05 ENST00000399575.2
proline rich, lacrimal 1
chr17_+_56315787 1.05 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr12_-_45270151 1.04 ENST00000429094.2
NEL-like 2 (chicken)
chr12_-_45270077 1.03 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr2_-_152830479 1.03 ENST00000360283.6
calcium channel, voltage-dependent, beta 4 subunit
chr5_-_110062349 1.03 ENST00000511883.2
ENST00000455884.2
transmembrane protein 232
chr20_-_52612468 1.02 ENST00000422805.1
breast carcinoma amplified sequence 1
chr2_+_102953608 1.02 ENST00000311734.2
ENST00000409584.1
interleukin 1 receptor-like 1
chr12_-_7818474 1.02 ENST00000229304.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr12_-_55375622 1.01 ENST00000316577.8
thymocyte expressed, positive selection associated 1
chr9_-_21187598 1.01 ENST00000421715.1
interferon, alpha 4
chrX_-_9734004 1.01 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr18_+_50278430 1.01 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
deleted in colorectal carcinoma
chr8_+_36641842 0.99 ENST00000523973.1
ENST00000399881.3
potassium channel, subfamily U, member 1
chr14_-_21055874 0.99 ENST00000553849.1
ribonuclease, RNase A family, 11 (non-active)
chr9_+_105757590 0.99 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr3_+_51863433 0.99 ENST00000444293.1
IQ motif containing F3
chr11_-_62997124 0.98 ENST00000306494.6
solute carrier family 22, member 25
chr2_+_234959376 0.98 ENST00000425558.1
secreted phosphoprotein 2, 24kDa
chr10_+_124670121 0.98 ENST00000368894.1
family with sequence similarity 24, member A
chr7_-_14942283 0.98 ENST00000402815.1
diacylglycerol kinase, beta 90kDa
chr6_+_127898312 0.97 ENST00000329722.7
chromosome 6 open reading frame 58
chr10_+_68685764 0.97 ENST00000361320.4
leucine rich repeat transmembrane neuronal 3
chr3_+_100354442 0.96 ENST00000475887.1
G protein-coupled receptor 128
chr22_-_50523688 0.96 ENST00000450140.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr12_-_45269769 0.96 ENST00000548826.1
NEL-like 2 (chicken)
chr3_-_108836945 0.95 ENST00000483760.1
MORC family CW-type zinc finger 1
chr8_-_120651020 0.94 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_-_88425025 0.94 ENST00000297203.2
chromosome 7 open reading frame 62
chr16_+_58283814 0.94 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chr15_+_42651691 0.94 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
calpain 3, (p94)
chr4_+_69962212 0.94 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr1_-_19615744 0.93 ENST00000361640.4
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr12_-_45269251 0.92 ENST00000553120.1
NEL-like 2 (chicken)
chr4_-_70505358 0.92 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UDP glucuronosyltransferase 2 family, polypeptide A2
chr7_-_18067478 0.92 ENST00000506618.2
phosphoribosyl pyrophosphate synthetase 1-like 1
chr4_-_34041504 0.92 ENST00000512581.1
ENST00000505018.1
RP11-79E3.3
chr19_-_3786354 0.91 ENST00000395040.2
ENST00000310132.6
megakaryocyte-associated tyrosine kinase
chr4_+_159442878 0.91 ENST00000307765.5
ENST00000423548.1
relaxin/insulin-like family peptide receptor 1
chr19_+_54466179 0.91 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr5_+_121465207 0.90 ENST00000296600.4
zinc finger protein 474
chr5_-_140683612 0.90 ENST00000239451.4
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
chr11_+_60467047 0.90 ENST00000300226.2
membrane-spanning 4-domains, subfamily A, member 8
chr14_-_74892805 0.90 ENST00000331628.3
ENST00000554953.1
synapse differentiation inducing 1-like
chr4_-_110736505 0.89 ENST00000609440.1
RP11-602N24.3
chr1_+_207262578 0.89 ENST00000243611.5
ENST00000367076.3
complement component 4 binding protein, beta
chr1_+_28099683 0.89 ENST00000373943.4
syntaxin 12
chr7_-_14942467 0.88 ENST00000407950.1
ENST00000444700.2
diacylglycerol kinase, beta 90kDa
chr12_-_81763184 0.87 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrX_+_49178536 0.87 ENST00000442437.2
G antigen 12J
chr6_+_35748783 0.87 ENST00000373861.5
ENST00000542261.1
colipase-like 1
chrX_+_30261847 0.87 ENST00000378981.3
ENST00000397550.1
melanoma antigen family B, 1
chr4_+_155484155 0.86 ENST00000509493.1
fibrinogen beta chain
chr4_+_71587669 0.86 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr11_-_47736896 0.85 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
ATP/GTP binding protein-like 2
chr12_-_64784306 0.84 ENST00000543259.1
chromosome 12 open reading frame 56
chr15_+_42697065 0.84 ENST00000565559.1
calpain 3, (p94)
chr10_+_124320156 0.84 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr12_-_81763127 0.83 ENST00000541017.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr22_+_18721427 0.83 ENST00000342888.3
Uncharacterized protein
chr4_+_159443090 0.82 ENST00000343542.5
ENST00000470033.1
relaxin/insulin-like family peptide receptor 1
chr19_+_18726786 0.82 ENST00000594709.1
transmembrane protein 59-like
chr10_-_79398250 0.82 ENST00000286627.5
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_+_69962185 0.81 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr22_+_41074754 0.81 ENST00000249016.4
melanin-concentrating hormone receptor 1
chr4_+_74347400 0.81 ENST00000226355.3
afamin
chr10_-_28270795 0.80 ENST00000545014.1
armadillo repeat containing 4
chr11_+_125658006 0.80 ENST00000445202.1
prostate and testis expressed 3
chr4_-_150736962 0.80 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
chrX_+_49363665 0.79 ENST00000381700.6
G antigen 1
chr11_+_134144139 0.79 ENST00000389887.5
galactosidase, beta 1-like 3
chr1_+_207262540 0.79 ENST00000452902.2
complement component 4 binding protein, beta
chr2_-_152830441 0.79 ENST00000534999.1
ENST00000397327.2
calcium channel, voltage-dependent, beta 4 subunit
chr7_+_128349106 0.79 ENST00000485070.1
family with sequence similarity 71, member F1
chr1_+_66820058 0.78 ENST00000480109.2
phosphodiesterase 4B, cAMP-specific

Network of associatons between targets according to the STRING database.

First level regulatory network of CUX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.3 3.8 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
1.2 3.6 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.8 3.9 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.7 2.0 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.6 6.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.6 1.8 GO:2000646 lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646)
0.5 2.0 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.4 1.3 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.4 1.7 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 0.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.4 1.2 GO:0006147 guanine catabolic process(GO:0006147)
0.4 4.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 5.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 1.1 GO:0017143 insecticide metabolic process(GO:0017143)
0.4 1.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.4 2.6 GO:0044026 DNA hypermethylation(GO:0044026)
0.4 1.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 2.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.3 1.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.3 2.7 GO:0007341 penetration of zona pellucida(GO:0007341)
0.3 3.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 3.2 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 1.9 GO:0061760 antifungal innate immune response(GO:0061760)
0.3 1.2 GO:1990502 dense core granule maturation(GO:1990502)
0.3 1.2 GO:0002215 defense response to nematode(GO:0002215)
0.3 1.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 5.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 0.8 GO:2001202 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.3 3.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 1.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 2.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.8 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.3 1.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.3 1.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.2 4.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 1.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 3.3 GO:0008228 opsonization(GO:0008228)
0.2 0.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 0.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 1.0 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.2 0.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 1.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) membrane depolarization during SA node cell action potential(GO:0086046)
0.2 3.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 1.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 2.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.9 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 3.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 2.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.9 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 2.8 GO:0007614 short-term memory(GO:0007614)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.5 GO:0051180 vitamin transport(GO:0051180)
0.1 1.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.7 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.3 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.4 GO:0001808 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.1 2.3 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 1.5 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.5 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 1.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 3.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 2.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.2 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 1.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 17.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 1.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 1.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.7 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.4 GO:0015865 purine nucleotide transport(GO:0015865)
0.1 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 3.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.8 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 3.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 3.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 2.2 GO:0032094 response to food(GO:0032094)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.6 GO:0030220 platelet formation(GO:0030220)
0.0 1.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 0.5 GO:0050957 equilibrioception(GO:0050957)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 2.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.4 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.7 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 2.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.0 2.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.5 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 5.4 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 1.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.1 GO:0044782 cilium organization(GO:0044782)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 1.0 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.4 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:1902953 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.3 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 2.0 GO:0046849 bone remodeling(GO:0046849)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.9 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 2.7 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0045634 regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.4 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.0 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 1.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 2.1 GO:0007605 sensory perception of sound(GO:0007605)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 9.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.5 1.0 GO:0033150 cytoskeletal calyx(GO:0033150)
0.4 1.3 GO:0043159 acrosomal matrix(GO:0043159)
0.3 1.4 GO:0002081 outer acrosomal membrane(GO:0002081)
0.3 2.7 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2 1.8 GO:0044305 calyx of Held(GO:0044305)
0.2 0.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.1 2.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 0.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.7 GO:0030673 axolemma(GO:0030673)
0.1 1.1 GO:0030061 mitochondrial crista(GO:0030061)
0.1 2.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 4.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 3.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 12.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 5.9 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 2.4 GO:0031201 SNARE complex(GO:0031201)
0.0 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.6 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 4.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 3.0 GO:0043204 perikaryon(GO:0043204)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.9 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
1.0 6.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.9 3.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.9 4.4 GO:0033265 choline binding(GO:0033265)
0.8 2.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.7 2.0 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.7 2.0 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.5 1.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4 1.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.4 2.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.4 1.6 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.4 3.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 1.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 1.0 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.3 1.3 GO:0004040 amidase activity(GO:0004040)
0.3 2.6 GO:0004064 arylesterase activity(GO:0004064)
0.3 2.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 7.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 3.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.8 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.9 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 0.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 2.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 0.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 3.6 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 3.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 3.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 2.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 5.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 1.9 GO:0015216 purine nucleotide transmembrane transporter activity(GO:0015216)
0.1 1.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.1 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.3 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 3.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 2.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.8 GO:0055103 titin binding(GO:0031432) ligase regulator activity(GO:0055103)
0.1 0.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.8 GO:0035198 miRNA binding(GO:0035198)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 2.2 GO:0001848 complement binding(GO:0001848)
0.1 21.2 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 2.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0045142 triplex DNA binding(GO:0045142)
0.0 0.6 GO:0032052 bile acid binding(GO:0032052)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.0 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 4.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 3.9 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0031403 lithium ion binding(GO:0031403)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.9 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 6.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 10.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 7.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 6.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 6.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 3.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 3.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.8 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 5.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus