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Illumina Body Map 2, young vs old

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Results for DBP

Z-value: 0.25

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Transcription factors associated with DBP

Gene Symbol Gene ID Gene Info
DBP
ENSG00000105516.6 D-box binding PAR bZIP transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DBPhg19_v2_chr19_-_49140609_49140643-0.431.5e-02Click!

Activity profile of DBP motif

Sorted Z-values of DBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_88427568 5.47 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr2_-_180610767 5.10 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr20_-_14318248 4.69 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr4_-_176733377 4.35 ENST00000505375.1
GPM6A
glycoprotein M6A
chr8_+_85618155 3.74 ENST00000523850.1
ENST00000521376.1
RALYL
RALY RNA binding protein-like
chr2_+_234602305 3.37 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chrX_-_10851762 3.29 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr6_-_94129244 3.24 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr8_+_99076509 3.04 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr1_+_154540246 2.95 ENST00000368476.3
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr10_+_74653330 2.94 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr8_+_99076750 2.93 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr4_-_186732048 2.86 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr5_-_95550754 2.81 ENST00000502437.1
RP11-254I22.3
RP11-254I22.3
chr4_-_23891693 2.77 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr15_-_27018175 2.67 ENST00000311550.5
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_+_210517895 2.65 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr12_+_79371565 2.64 ENST00000551304.1
SYT1
synaptotagmin I
chr2_+_234601512 2.63 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr9_-_112083229 2.48 ENST00000374566.3
ENST00000374557.4
EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr2_-_21266935 2.48 ENST00000233242.1
APOB
apolipoprotein B
chr2_-_216257849 2.47 ENST00000456923.1
FN1
fibronectin 1
chr20_-_22559211 2.44 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr10_-_98118724 2.43 ENST00000393870.2
OPALIN
oligodendrocytic myelin paranodal and inner loop protein
chr4_+_88754113 2.42 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr7_+_114055052 2.36 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr17_+_72426891 2.33 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr18_-_25616519 2.27 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr3_-_48471454 2.24 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr13_+_44947941 2.24 ENST00000379179.3
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr12_-_99548645 2.20 ENST00000549025.2
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_+_210444748 2.17 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr15_+_69854027 2.15 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr12_+_7169887 2.12 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr11_-_31832581 2.12 ENST00000379111.2
PAX6
paired box 6
chr7_+_103969104 2.08 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
LHFPL3
lipoma HMGIC fusion partner-like 3
chr1_+_57320437 2.06 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr16_+_7382745 2.06 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr21_+_17791648 2.05 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_162039558 2.04 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr15_+_58702742 1.98 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr2_+_210444142 1.96 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr2_+_169658928 1.95 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr8_+_85095553 1.92 ENST00000521268.1
RALYL
RALY RNA binding protein-like
chr13_+_93879085 1.91 ENST00000377047.4
GPC6
glypican 6
chr4_-_176733897 1.90 ENST00000393658.2
GPM6A
glycoprotein M6A
chr2_+_182850743 1.90 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_169659121 1.90 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr2_+_166326157 1.89 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr4_+_88754069 1.88 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr1_-_85870177 1.86 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr19_-_22715280 1.82 ENST00000593802.1
ZNF98
zinc finger protein 98
chr15_+_78632666 1.76 ENST00000299529.6
CRABP1
cellular retinoic acid binding protein 1
chr3_+_72201910 1.72 ENST00000469178.1
ENST00000485404.1
LINC00870
long intergenic non-protein coding RNA 870
chr15_+_80733570 1.71 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chrX_+_28605516 1.70 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr18_+_31185530 1.69 ENST00000586327.1
ASXL3
additional sex combs like 3 (Drosophila)
chr10_+_60936921 1.68 ENST00000373878.3
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr15_+_48483736 1.63 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr2_+_95963052 1.62 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr8_+_85095769 1.62 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr21_+_17791838 1.61 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_82266053 1.60 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr8_-_17533838 1.58 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr6_-_117747015 1.58 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr7_-_121784285 1.57 ENST00000417368.2
AASS
aminoadipate-semialdehyde synthase
chr11_-_47206965 1.55 ENST00000525725.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr6_-_31514516 1.54 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr7_+_35756186 1.52 ENST00000430518.1
AC018647.3
AC018647.3
chr5_+_161495038 1.51 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr16_+_2059872 1.49 ENST00000567649.1
NPW
neuropeptide W
chr5_+_161494770 1.48 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_+_210444298 1.48 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr5_-_27038683 1.48 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)
chr3_+_184097836 1.47 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr4_-_76555657 1.47 ENST00000307465.4
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr12_-_6483969 1.46 ENST00000396966.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr5_+_161494521 1.45 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr17_-_56492989 1.43 ENST00000583753.1
RNF43
ring finger protein 43
chr14_+_29234870 1.42 ENST00000382535.3
FOXG1
forkhead box G1
chr3_-_145878954 1.42 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr1_-_196577489 1.42 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
KCNT2
potassium channel, subfamily T, member 2
chr4_-_20985632 1.39 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr17_-_34308524 1.36 ENST00000293275.3
CCL16
chemokine (C-C motif) ligand 16
chr14_-_73360796 1.35 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr3_+_123813509 1.35 ENST00000460856.1
ENST00000240874.3
KALRN
kalirin, RhoGEF kinase
chr15_+_71389281 1.35 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr17_-_37764128 1.34 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr21_+_34398153 1.33 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
OLIG2
oligodendrocyte lineage transcription factor 2
chr8_-_102803163 1.31 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr11_+_112832090 1.31 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr2_-_152830479 1.31 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_-_31514333 1.26 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr16_+_67022633 1.26 ENST00000398354.1
ENST00000326686.5
CES4A
carboxylesterase 4A
chr5_-_124080203 1.25 ENST00000504926.1
ZNF608
zinc finger protein 608
chrX_-_151619746 1.24 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr7_+_35756092 1.23 ENST00000458087.3
AC018647.3
AC018647.3
chr14_-_24047965 1.22 ENST00000397118.3
ENST00000356300.4
JPH4
junctophilin 4
chr6_+_10528560 1.21 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr15_+_34261089 1.20 ENST00000383263.5
CHRM5
cholinergic receptor, muscarinic 5
chr11_+_394196 1.20 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr6_+_53976285 1.20 ENST00000514433.1
MLIP
muscular LMNA-interacting protein
chr6_+_53976235 1.19 ENST00000502396.1
ENST00000358276.5
MLIP
muscular LMNA-interacting protein
chr16_+_29789561 1.19 ENST00000400752.4
ZG16
zymogen granule protein 16
chr4_+_158142750 1.18 ENST00000505888.1
ENST00000449365.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr10_-_79397316 1.18 ENST00000372421.5
ENST00000457953.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_+_35721106 1.18 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr10_+_24755416 1.18 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr18_+_18943554 1.17 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr10_+_695888 1.17 ENST00000441152.2
PRR26
proline rich 26
chr2_-_21266816 1.17 ENST00000399256.4
APOB
apolipoprotein B
chr11_-_84634447 1.16 ENST00000532653.1
DLG2
discs, large homolog 2 (Drosophila)
chr10_-_104178857 1.15 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr3_+_184097905 1.14 ENST00000450923.1
CHRD
chordin
chr16_+_67022582 1.14 ENST00000541479.1
ENST00000338718.4
CES4A
carboxylesterase 4A
chr5_-_45696253 1.14 ENST00000303230.4
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr6_+_3118926 1.14 ENST00000380379.5
BPHL
biphenyl hydrolase-like (serine hydrolase)
chr10_-_79397202 1.13 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr15_+_34260921 1.13 ENST00000560035.1
CHRM5
cholinergic receptor, muscarinic 5
chr3_+_40141502 1.13 ENST00000539167.1
MYRIP
myosin VIIA and Rab interacting protein
chr10_-_79397391 1.10 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_+_19183671 1.09 ENST00000562711.2
SYT17
synaptotagmin XVII
chr2_-_164592497 1.09 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr7_-_50633078 1.09 ENST00000444124.2
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr15_+_71228826 1.08 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr4_-_87281196 1.06 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr4_+_71587669 1.04 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr16_+_67022476 1.03 ENST00000540947.2
CES4A
carboxylesterase 4A
chr6_-_138866823 1.03 ENST00000342260.5
NHSL1
NHS-like 1
chr3_+_190333097 1.02 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr16_-_75282088 1.02 ENST00000542031.2
BCAR1
breast cancer anti-estrogen resistance 1
chr8_+_65492756 1.02 ENST00000321870.1
BHLHE22
basic helix-loop-helix family, member e22
chr1_+_114522049 1.01 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr14_-_23652849 0.99 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr3_+_184098065 0.99 ENST00000348986.3
CHRD
chordin
chr4_-_186732241 0.95 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr4_+_113970772 0.94 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr12_-_99548524 0.94 ENST00000549558.2
ENST00000550693.2
ENST00000549493.2
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_71588372 0.94 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr4_-_87279641 0.93 ENST00000512689.1
MAPK10
mitogen-activated protein kinase 10
chr1_+_61547405 0.92 ENST00000371189.4
NFIA
nuclear factor I/A
chr9_-_13165457 0.91 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr11_+_112832202 0.91 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr20_+_44650348 0.90 ENST00000454036.2
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr5_-_67829357 0.89 ENST00000515199.1
CTC-537E7.2
CTC-537E7.2
chr3_-_23958402 0.87 ENST00000415901.2
ENST00000416026.2
ENST00000412028.1
ENST00000388759.3
ENST00000437230.1
NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr7_-_22234381 0.87 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr8_-_18711866 0.87 ENST00000519851.1
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_227505289 0.86 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr13_-_67802549 0.85 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr14_+_32963433 0.85 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr4_-_184243561 0.85 ENST00000514470.1
ENST00000541814.1
CLDN24
claudin 24
chr5_-_41510725 0.84 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr8_+_16884740 0.84 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr8_-_40755333 0.84 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chrX_-_83442915 0.83 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr22_+_38201114 0.83 ENST00000340857.2
H1F0
H1 histone family, member 0
chr6_+_33168189 0.81 ENST00000444757.1
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr2_+_166430619 0.81 ENST00000409420.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr3_+_35721182 0.79 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr18_-_35145981 0.79 ENST00000420428.2
ENST00000412753.1
CELF4
CUGBP, Elav-like family member 4
chr10_+_68685764 0.79 ENST00000361320.4
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr13_+_31506818 0.78 ENST00000380473.3
TEX26
testis expressed 26
chr10_-_100995540 0.77 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chr6_-_56819385 0.77 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr4_-_100242549 0.77 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_+_394145 0.76 ENST00000528036.1
PKP3
plakophilin 3
chr4_-_87278857 0.76 ENST00000509464.1
ENST00000511167.1
MAPK10
mitogen-activated protein kinase 10
chr6_+_33168597 0.75 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr17_-_27333311 0.74 ENST00000317338.12
ENST00000585644.1
SEZ6
seizure related 6 homolog (mouse)
chr6_+_33168637 0.74 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr17_-_48546232 0.74 ENST00000258969.4
CHAD
chondroadherin
chr4_-_87281224 0.74 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr6_-_55740352 0.74 ENST00000370830.3
BMP5
bone morphogenetic protein 5
chr8_-_29120580 0.73 ENST00000524189.1
KIF13B
kinesin family member 13B
chrX_-_24045303 0.73 ENST00000328046.8
KLHL15
kelch-like family member 15
chr3_+_123813543 0.73 ENST00000360013.3
KALRN
kalirin, RhoGEF kinase
chr1_+_82165350 0.73 ENST00000359929.3
LPHN2
latrophilin 2
chr11_-_84634217 0.73 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chrX_-_124097620 0.72 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr4_+_114214125 0.72 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr12_+_18891045 0.71 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr1_+_61547894 0.71 ENST00000403491.3
NFIA
nuclear factor I/A
chr8_+_77316233 0.70 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
RP11-706J10.3
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr4_+_106473768 0.70 ENST00000265154.2
ENST00000420470.2
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr8_+_77593474 0.69 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr8_-_114449112 0.69 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr17_-_48546324 0.68 ENST00000508540.1
CHAD
chondroadherin
chr2_-_183731882 0.67 ENST00000295113.4
FRZB
frizzled-related protein
chr10_-_48050538 0.66 ENST00000420079.2
ASAH2C
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2C
chrX_+_149531524 0.66 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr16_-_58328923 0.65 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr4_-_87279520 0.65 ENST00000506773.1
MAPK10
mitogen-activated protein kinase 10
chr2_+_105050794 0.64 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr8_-_54755459 0.64 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr11_+_112832133 0.62 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr12_-_18890940 0.62 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr5_-_16916624 0.62 ENST00000513882.1
MYO10
myosin X
chr20_+_11898507 0.62 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr16_-_58328870 0.62 ENST00000543437.1
PRSS54
protease, serine, 54

Network of associatons between targets according to the STRING database.

First level regulatory network of DBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.9 2.7 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.8 2.5 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.8 2.3 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.7 2.9 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.7 2.0 GO:1903947 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.6 2.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.5 6.0 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5 3.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.4 3.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 1.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 2.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 2.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.4 1.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.4 1.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 1.4 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.4 1.8 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.3 5.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.3 4.0 GO:0034465 response to carbon monoxide(GO:0034465)
0.3 1.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.3 5.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 1.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.3 7.1 GO:0071420 cellular response to histamine(GO:0071420)
0.3 0.9 GO:0040040 thermosensory behavior(GO:0040040)
0.3 4.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 1.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.3 1.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 2.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.3 2.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.2 2.5 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 3.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 2.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 2.0 GO:0002159 desmosome assembly(GO:0002159)
0.2 3.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.5 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.2 0.5 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 0.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 1.7 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 4.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 1.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 2.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.7 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.1 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0007343 egg activation(GO:0007343)
0.1 1.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 7.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.4 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.7 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 3.4 GO:0060074 synapse maturation(GO:0060074)
0.1 1.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 1.9 GO:0006527 arginine catabolic process(GO:0006527) negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.8 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 1.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 2.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.8 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 3.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 4.1 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.1 0.2 GO:0060279 negative regulation of B cell differentiation(GO:0045578) positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 2.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 2.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.0 GO:0097475 motor neuron migration(GO:0097475)
0.1 8.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 2.5 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.5 GO:1902993 positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 1.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 2.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 2.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.8 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 2.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 3.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 1.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 5.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 1.6 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc II ion transmembrane transport(GO:0071577)
0.0 0.8 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 2.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.0 GO:0015695 organic cation transport(GO:0015695)
0.0 1.0 GO:0048012 cellular response to hepatocyte growth factor stimulus(GO:0035729) hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 2.5 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.5 GO:0021554 optic nerve development(GO:0021554)
0.0 1.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.9 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.0 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0048702 protein sulfation(GO:0006477) embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 3.0 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 2.8 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 3.3 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.3 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 2.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.1 GO:0001942 hair follicle development(GO:0001942)
0.0 1.5 GO:0007631 feeding behavior(GO:0007631)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 2.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 3.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 1.1 GO:0098855 HCN channel complex(GO:0098855)
0.3 5.5 GO:0045179 apical cortex(GO:0045179)
0.3 2.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 11.0 GO:0044295 axonal growth cone(GO:0044295)
0.2 8.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 2.1 GO:0005579 membrane attack complex(GO:0005579)
0.2 2.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 2.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 4.4 GO:0097440 apical dendrite(GO:0097440)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 2.6 GO:0016342 catenin complex(GO:0016342)
0.1 2.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 2.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.9 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 12.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.9 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 2.3 GO:0071437 invadopodium(GO:0071437)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 2.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.1 GO:0031045 dense core granule(GO:0031045)
0.0 4.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 3.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 3.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 6.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 2.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 5.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 4.2 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.8 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.8 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.7 4.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 1.4 GO:0030305 heparanase activity(GO:0030305)
0.5 1.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.5 3.6 GO:0035473 lipase binding(GO:0035473)
0.4 4.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.4 5.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.4 3.6 GO:0045545 syndecan binding(GO:0045545)
0.4 1.4 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 4.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 3.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 9.1 GO:0002162 dystroglycan binding(GO:0002162)
0.3 1.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 2.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 1.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 2.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.9 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 4.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.0 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 6.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 4.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.1 0.8 GO:0042835 BRE binding(GO:0042835)
0.1 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 3.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 2.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 5.4 GO:0002039 p53 binding(GO:0002039)
0.0 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 2.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 3.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 1.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 3.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 2.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 1.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 2.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.2 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 2.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 7.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 4.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.6 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.4 ST ADRENERGIC Adrenergic Pathway
0.0 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 PID FGF PATHWAY FGF signaling pathway
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.8 PID P73PATHWAY p73 transcription factor network
0.0 5.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.7 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 6.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 2.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 4.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 4.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 3.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 4.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 4.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 2.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 5.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events